Clinical trials: Observational Study
Blood Platelet Disorders, Cardiac Surgery
Observational Study of Platelet Dysfunction Assessed by Thromboelastography in Cardiovascular Surgery (DISPLATEG)
Perioperative bleeding requiring blood transfusion is common during cardiovascular surgery, especially in procedures requiring cardiopulmonary bypass. Adenosine diphosphate (ADP) plays a fundamental role in platelet function.
- Conditions
- Blood Platelet Disorders, Cardiac Surgery, Postoperative Bleeding
- Trial name
- DISPLATEG (NCT06961175)
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
Alpine Accident, Frostbite
10-years Nationwide Alpine Accidents in Austria
This observational study intends to analyze the characteristic of specific accidents happened in Austrian's mountainous regions.
- Conditions
- Alpine Accident, Frostbite, Cardiopulmonary Arrest With Successful Resuscitation, Lightning Injuries
- Trial name
- NCT03405467
- Testing
- general and specific data
- Where
- Austria
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Endometrial Neoplasms
An Observational Study Based on Endometrial Cancer Risk Screening Model
The goal of this observational study is to test the efficiency of our endometrial cancer risk screening calculator, and improve the endometrial cancer risk screening model to form a stable and reliable non-invasive auxiliary…
- Trial name
- NCT05634798
- Testing
- no intervention
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
RSV Infection in Children Less Than 5 Years of Age, General Anesthesia
The Effect of Sevoflurane on Airway Hyperreactivity During the Perioperative Period.
To investigate the effects of sevoflurane on respiratory parameters and respiratory inflammation in healthy and RSV-infected under general anesthesia and to propose suitable perioperative airway protection measures for children…
- Trial name
- NCT06694675
- Testing
- Sevoflurane (Volatile Anesthetic), propofol
- Where
- 2 sites in China
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- First Hospital of China Medical University
Acute Respiratory Failure, Mechanical Ventilation
A Study of Communication Between Clinicians, Patients, and Families in the Intensive Care Unit (ICU)
The purpose of this study is to investigate a specific approach to patient care called a time-limited trial (TLT). This approach is sometimes used for people who develop critical illness and are cared for in an intensive care…
- Conditions
- Acute Respiratory Failure, Mechanical Ventilation, Life-Supporting Treatments, Communication
- Trial name
- TIME (NCT06042621)
- Where
- 5 sites in United States
- Volunteers
- 7,818 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Pain, Estradiol
Estrogen and Propofol Injection Pain
This prospective observational study investigates the relationship between serum estrogen concentration and the incidence and severity of propofol injection pain (PIP) in female patients undergoing general anesthesia.
- Conditions
- Pain, Estradiol, Assisted Reproductive Techniques
- Trial name
- NCT06929416
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Hemostasis, Perioperative Bleeding
Appropriateness of Hemostatic Agent Use in Cardiovascular Surgery (HAEMOVAX)
Hemostatic agents are widely used in cardiac and vascular surgery to support intraoperative bleeding control. Despite their clinical relevance and substantial economic impact, little is known about real-world patterns of use…
- Conditions
- Hemostasis, Perioperative Bleeding, Cardiovascular Surgery, Cardiac Surgery
- Trial name
- HAEMOVAX (NCT07699016)
- Testing
- observational study
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Milan
Healthy
An Observational Study to Assess Respiratory Syncytial Virus (RSV) Respiratory Events Among Premature Infants
The primary objective is to assess the burden of respiratory disease in outpatient settings among 32 to 35 weeks' gestational age (wGA) infants in the USA who did not receive RSV prophylaxis during the infants' first RSV season.
- Trial name
- NCT00983606
- Where
- 222 sites in United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
No Condition, Skin Carotenoids and Immune-aging
Carotenoids in the Skin and Immune Aging
This study aims to examine the connection between the level of carotenoids in the skin and a number of immune related health parameters.
- Trial name
- NCT07221643
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stanford University
COVID-19
COVID-19 Lessons Learned: the Outcome of TOMEKA® Project is to Teach
Living in Canada and being health-worker in the first line face to COVID-19, investigator outcome is to teach an experience or explain the disease using a review and get people prepared to COVID-19 treatment focused on adherence…
- Trial name
- MD (NCT04424940)
- Where
- Democratic Republic of the Congo
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Kinshasa
Neuroma
Regenerative Peripheral Nerve Interfaces to Treat Painful Digit and Hand Neuromas After Amputation
This study is being done to demonstrate the effectiveness of Regenerative Peripheral Nerve Interfaces (RPNI) surgery in treating symptomatic neuromas of the hand and digits following amputation compared to standard of care using…
- Trial name
- NCT05008185
- Testing
- Regenerative Peripheral Nerve Interface (RPNI) surgery, Traction Neurectomy
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Cardiac Arrhythmia
Comparing Sensitivity and Specificity of Pacemaker ID Application and Cardiac Rhythm Management Device-Finder Application.
Smart phone-based applications to identify cardiac implantable electronic devices (CIED) are extremely useful in circumstances where urgent device interrogation is needed and device identification card is not available.
- Trial name
- NCT04957108
- Testing
- Device identification using Xray.
- Where
- Pakistan
- Volunteers
- 547 people, healthy volunteers welcome
- Sponsor
- Aga Khan University Hospital, Pakistan
Gingivitis and Periodontal Diseases
Investigating the Periodontal Status of Traditional and Heated Tobacco Product Users
This cross-sectional observational study aims to compare the clinical and radiographic periodontal status, as well as gingival crevicular fluid volume, among cigarette smokers, heated-tobacco product users, and non-smokers.
- Trial name
- INPER-THT (NCT06784817)
- Where
- Hungary
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Low Back Pain
Study of Low Back Pain Using CERSR® Imaging Technology
The purpose of this research study is to measure with CERSR® (Computerized Electrophysiological Reconstruction of the Spinal Regions) the electrical signals made by the muscles in the lower back 1) when the subject has no low…
- Trial name
- NCT01401660
- Testing
- Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Verium Diagnostics, Inc.
HIV
Non-Interventional Observational Retrospective Study to Evaluate Doravirine Based-regimens in HIV Infected Aged Patients (DORAge).
The HIV-infected population is aging due to the success of combination antiretroviral therapy, which prolongs survival, as well as the growing number of newly diagnosed cases in adults 50 years old and over.
- Trial name
- DORAge (NCT05202613)
- Testing
- Doravirine
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Major Depressive Disorder (MDD), fNIRS
Prediction of REsponse to Depression Interventions (Accelerated rTMS) Using Clinical and TD-fNIRS Measurements
This observational, longitudinal, multi-cohort study aims to evaluate functional brain activity in adults undergoing treatment for Major Depressive Disorder (MDD) at participating clinical sites.
- Trial name
- PREDICT-ACC (NCT07294924)
- Testing
- fNIRS measurement
- Where
- 2 sites in United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Kernel
Healthy
A Study to Describe Pediatric Influenza Vaccine Coverage
The purpose of this study is to describe flu vaccine coverage in children under 18 years of age and to examine correlations between in-office flu vaccine coverage and the use of various tactics to increase vaccine coverage.
- Trial name
- NCT00639418
- Testing
- Influenza vaccination
- Where
- 187 sites in United States
- Volunteers
- 147,494 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Prevention
Glucose Observation and Wearable Use for Prevention
The GLOW UP study is a single-center, prospective, observational case-control study conducted in St. Gallen, Switzerland. The primary aim of the study is to examine to what degree lifestyle data collected from wearable devices…
- Trial name
- GlowUp (NCT07373418)
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of St.Gallen
Perfusion Index, Position Differences
Evaluation Of The Effects Of Changes In Operating Table Position On Perfusion Index And Spinal Anesthesia
The aim of this observational study is to investigate how table position affects the development of block in patients undergoing spinal anesthesia. Perfusion index measurements will be used to answer this question.
- Trial name
- Perfusion (NCT07400185)
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Enes Celik
Melanoma, Renal Cancer
Microbiome Immunotherapy Toxicity and Response Evaluation
This is a observational study to investigate how the microbiome correlates with efficacy and toxicity of immune checkpoint inhibitors in patients with advanced cancer.
- Conditions
- Melanoma, Renal Cancer, Lung Cancer
- Trial name
- NCT04107168
- Testing
- Nivolumab, Pembrolizumab, Ipilimumab
- Where
- 13 sites in United Kingdom
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- CCTU- Cancer Theme