Clinical trials: Observatory
Multiple Sclerosis
Evaluation of Potential Accumulation of Gadolinium (Dotarem and Multihance) in the French Observatory of Multiple Sclerosis (Www.Ofsep.Org/)
Several recent studies have shown an increase in the signal intensity of the unenhanced T1-weighted magnetic resonance images in the brain of patients with normal renal functions and a breakdown of the blood-brain barrier.
- Trial name
- NCT02992847
- Testing
- Unenhanced MRI
- Volunteers
- 160 people
- Sponsor
- Hospices Civils de Lyon
Digestive System Neoplasms, Surgery
Observatory of the Quality of Surgical Procedures for Digestive Cancers
Surgery for digestive cancers is managed according to quality standards, validated by the scientific community. Despite the diffusion of these standards through the benchmarks of good practice, the results of the surgery remain…
- Conditions
- Digestive System Neoplasms, Surgery, Surgery--Complications, Quality of Health Care
- Trial name
- Obchir (NCT03681600)
- Where
- 4 sites in Morocco
- Volunteers
- 1,043 people
- Sponsor
- Moroccan Society of Surgery
Cochlear Implants
Middle East MED-EL Observatory Study
In the field of cochlear implant research, there are only few data on long-term observational studies available to gain knowledge on clinical effectiveness.
- Trial name
- MEMOS (NCT03882229)
- Testing
- MED-EL CI systems
- Where
- 3 sites in Egypt, Saudi Arabia
- Volunteers
- 100 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Hip Surgery
Post Market Clinical Follow-up of Hip Surgery Using FH ORTHO Company Medical Devices.
The objective of this observatory is to generate additional real life clinical data in accordance with local regulation (i.e. Post-Market Clinical Follow-up (PMCF) study, a study carried out following the European Conformity (CE)…
- Trial name
- HipFHOrtho (NCT05966220)
- Testing
- Hip surgery with FH Ortho devices
- Where
- 5 sites in France
- Volunteers
- 800 people
- Sponsor
- FH ORTHO
Psychiatric Disorder, Covid19
PSYCHIATRIC Disorders and Covid-19
Given the possible risks and complications of a comorbidity between psychiatric disorder and coronavirus disease 2019 (COVID-19), it seems particularly important to specify the impact of the COVID-19 pandemic in patients with…
- Trial name
- PSYCHIC (NCT04358042)
- Testing
- Brief Psychiatric Rating Scale, Depression, Anxiety and Stress Scale, Impact of Event Scale-Revised
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Nantes University Hospital
Ovarian Tumors
French Observatory of Rare Malignant Tumors of the Ovary
To take charge of the treatment in rare adult ovarian tumors with an homogenous manner (germinal and sexual cords tumors), at different stages of the disease.
- Trial name
- NCT01304043
- Testing
- chemotherapies protocols
- Where
- France
- Volunteers
- 204 people
- Sponsor
- ARCAGY/ GINECO GROUP
Bronchiolitis, Pneumonia
National Observatory of Children Hospitalized for Acute Respiratory Distress or Lower Respiratory Tract Infections
This study is an observational, multicenter and prospective study for surveillance of case of hospitalised children acute respiratory distress or lower respiratory tract infections
- Conditions
- Bronchiolitis, Pneumonia, Asthma
- Trial name
- OVNI (NCT06112132)
- Where
- France
- Volunteers
- 1,827 people
- Sponsor
- Association Clinique Thérapeutique Infantile du val de Marne
Child Allergy, IgE-Mediated Allergic Process
Observatory of the Lille Paediatric Allergy Unit
The goal of this study is to set up a paediatric observatory within the allergology department of The saint Vincent Hospital, Lille.
- Conditions
- Child Allergy, IgE-Mediated Allergic Process, Food Allergy
- Trial name
- PAUL (NCT06634992)
- Testing
- Oral immunotherapy
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Lille Catholic University
Aortic Valve Disease
Observatory of Anticoagulation After Bioprosthetic Aortic Valve Replacement
The bioprosthetic aortic valve replacement is a frequent intervention because of the predominance of calcified aortic stenosis, which is the most common valvular disease, and aging of the population.
- Trial name
- ARVA (NCT01293188)
- Where
- France
- Volunteers
- 434 people
- Sponsor
- French Cardiology Society
Stroke
Stroke Observatory of Caen-Normandie Metropole
Stroke Observatory of Caen-Normandy Metropole provides epidemiological data in prospective collection. The primary objective is to determinate incidence of Stroke in this area.
- Trial name
- NORMANDYSTROKE (NCT03684226)
- Where
- France
- Volunteers
- 2,400 people
- Sponsor
- University Hospital, Caen
Liver Diseases, COVID19
COVID19-FOIE National Observatory
Background: The COVID19 and liver relationships are very rare. The preliminary Chinese data indicate that 2-11% of patients treated for COVID19 had an underlying chronic liver disease.
- Trial name
- NCT04375670
- Where
- France
- Volunteers
- 1,132 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myocarditis, Cardiomyopathy, Dilated
French National Observatory Tracking Viral Myocarditis: Mortality, Cardiovascular Events, Sequels on (Magnetic Resonance Imaging) MRI
Acute myocarditis is a serious illness affecting a young population with a very variable course (of full recovery at the onset of dilated cardiomyopathy (DCM), or even sudden death).
- Conditions
- Myocarditis, Cardiomyopathy, Dilated, Magnetic Resonance Imaging
- Trial name
- MYOCARDITIRM (NCT02717143)
- Where
- France
- Volunteers
- 821 people
- Sponsor
- French Cardiology Society
Heart Failure
FRENCH OBSERVATORY OF ACUTE HEART FAILURE-2
In 2009, OFICA 1 provided a snapshot of the management of acute heart failure in France. Over the past 10 years, practitioners have observed a change in the profiles of hospitalized patients and it is necessary to specify the…
- Trial name
- OFICA2 (NCT05232058)
- Where
- France
- Volunteers
- 1,593 people
- Sponsor
- French Cardiology Society
Prostate Cancer
Consensus Method to Evaluate the Conformity of Prescription of a Chemotherapy
Cabazitaxel is a second line chemotherapy drug recently approved for the treatment of metastatic castration-resistant prostate cancer.
- Trial name
- CABOBS (NCT02882178)
- Volunteers
- 18 people
- Sponsor
- Institut Bergonié
Laminopathies, Emerinopathies
Observatoire Des Patients Atteints de Laminopathies et Emerinopathies (Observatory for PAtients With Laminopathies and Emerinopathies)
Laminopathies and emerinopathies are complex group of rare disorders due to mutations in A-type lamins (LMNA) and Emerin (EMD) genes.
- Trial name
- OPALE (NCT03058185)
- Where
- 29 sites in France
- Volunteers
- 800 people
- Sponsor
- Pitié-Salpêtrière Hospital
Acute Lymphoblastic Leukemia
EWALL-PH OBSERVARTORY 2022
An observatory for patients aged 18 years and over with Philadelphia chromosome positive (Ph+ or BCR::ABL1) acute lymphoblastic leukemia (ALL) and treated with the combination of BCR::ABL1 inhibitors and chemotherapy and/or…
- Trial name
- Ewall Obs 2022 (NCT07684131)
- Where
- 23 sites in France
- Volunteers
- 100 people
- Sponsor
- Versailles Hospital
Polyps
Endoscopic Mucosal Colonic Resection and Polypectomy Under Aspirin
The endoscopic management of patients on anti platelet agents is a wide problem more and more common, with prevalence of patients on this type of therapy steadily increasing.
- Trial name
- OPERA (NCT01481337)
- Testing
- Colonic polypectomy or endoscopic mucosal resection (EMR)
- Where
- France
- Volunteers
- 317 people
- Sponsor
- Société Française d'Endoscopie Digestive
Unexpected Delivery Outside Maternity
Observatory of Unintentional Births Hospital Extras
In France, pre-hospital unexpected birth is a rare situation, but over the last ten years, the investigators have seen an increase in the number of these.
- Trial name
- AIEH34 (NCT03820505)
- Where
- France
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Shock, Cardiogenic
French Observatory on the Management of Cardiogenic Shock in 2016
Cardiogenic shock (CS) is defined as an organ hypoperfusion secondary to low cardiac output. Catches diagnostic management, and therapeutic monitoring of these patients remain highly variable from one center to another and even…
- Trial name
- FRENSHOCK (NCT02703038)
- Where
- France
- Volunteers
- 777 people
- Sponsor
- French Cardiology Society
Breast Cancer, Breast Neoplasms
Study of the Sexual Health of Patients Treated for Breast Cancer and Followed up in the Observatory of Fertility at Jeanne de Flandre Hospital.
Study of sexual health by repeated anonymous self-administered questionnaires in patients treated for non-metastatic breast cancer and referred to Jeanne de Flandre hospital for possible preservation of their fertility.
- Conditions
- Breast Cancer, Breast Neoplasms, Breast Carcinoma, Breast Tumor
- Trial name
- ENVIE (NCT04852926)
- Testing
- Self-administered questionnaires
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Lille