Clinical trials: Obsessive Compulsive Disorder
Obsessive-Compulsive Disorder, EEG With Periodic Abnormalities
EEG Results of Deep TMS in Patients With OCD
Obsessive Compulsive Disorder (OCD) is a psychiatric disorder in which involuntary thoughts and irresistible behaviors are seen and its prevalence affects 2%-3% of the general population.
- Trial name
- NCT05188833
- Testing
- Deep Transcranial Magnetic Stimulation, Paroxetine
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
OCD, Major Depressive Disorder (MDD)
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
This is an observational study which does NOT directly administer a psychedelic substance but rather recruits participants who are already participating in another clinical trial in which they may receive a serotonergic…
- Conditions
- OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer
- Trial name
- NCT06624137
- Testing
- Serotonergic Psychedelic
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Yale University
Obsessive Compulsive Disorder
Deep Brain Stimulation of NAc/ALIC to Prevent Treatment-Refractory Obsessive Compulsive Disorder
Nucleus accumbens/anterior limb of internal capsule play important roles in the process of treatment-refractory obsessive compulsive disorder, deep brain stimulation of nucleus accumbens/anterior limb of internal capsule will…
- Trial name
- NCT02601677
- Testing
- Deep brain stimulation, Fluoxetine
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Obsessive-Compulsive Disorder
Study on the Efficacy Mechanism of Natural Psychotherapy for Neurosis
explore objective indicators of the efficacy of natural psychotherapy in the treatment of disorders such as obsessive-compulsive disorder
- Trial name
- NCT05552014
- Testing
- Natural Psychotherapy, waitlist control group
- Where
- 2 sites in China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Beijing HuiLongGuan Hospital
Obsessive-Compulsive Disorder
Phase II Adaptive Deep Brain Stimulation for Obsessive-Compulsive Disorder
This research study is for participants that have been diagnosed with intractable Obsessive -compulsive disorder (OCD). OCD is a persistent and oftentimes disabling disorder marked by unwanted and distressing thoughts…
- Trial name
- NCT04806516
- Testing
- Summit RC+S System with ECoG Paddles, One Month Blinded Discontinuation Period:
- Where
- 3 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Obsessive-compulsive Disorders and Symptoms in Children
Task Control Circuit Targets for Obsessive Compulsive Behaviors in Children
This study will use magnetic resonance imaging (MRI) to assess the function and structure of overlapping task control circuits in children with a range of Obsessive-Compulsive symptoms (OCS).
- Trial name
- NCT03584945
- Testing
- Cognitive Behavioral Therapy, Community Referral as appropriate
- Where
- 2 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obsessive-Compulsive Disorder
The Neurocircuitry of Relief During Avoidance Learning in Patients With Obsessive-compulsive Disorder
To investigate the neuro-mechanisms underpinning persistent avoidance in OCD patients
- Trial name
- AvoidOCD (NCT04685018)
- Testing
- fMRI acquisition
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Obsessive-Compulsive Disorder
Development of Adaptive Deep Brain Stimulation for OCD
This research study is for participants that have been diagnosed with intractable Obsessive -compulsive disorder (OCD). OCD is a persistent and oftentimes disabling disorder marked by unwanted and distressing thoughts…
- Trial name
- Phase Ib (NCT04281134)
- Testing
- Summit RC+S System, One Month Blinded Discontinuation Period:
- Where
- 3 sites in United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Obsessive-Compulsive Disorder
Mindfulness Meditation Utilizing an EEG Biofeedback Device for the Treatment for Obsessive Compulsive Disorder
The Frederick W. Thompson Anxiety Disorders Centre has experienced significant demand for services related to the treatment of Obsessive Compulsive Disorder (OCD), resulting in a significant wait time for service.
- Trial name
- NCT03273699
- Testing
- Mindfulness
- Where
- Canada
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Healthy, Mental Disorder
I-123 Brain Studies of Serotonin Metabolism in Psychiatric Patients and Normal Volunteers
Abnormalities in the re-uptake of dopamine and serotonin have been described in various neuropsychiatric disorders and substance abuse.
- Conditions
- Healthy, Mental Disorder, Obsessive Compulsive Disorder, Schizophrenia
- Trial name
- NCT00001771
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
OCD
Effects of Sertraline on Brain Connectivity in Adolescents With OCD
The investigators will examine how treatment with sertraline for 12 weeks impacts frontal-striatal-thalamic circuitry (FSTC) in this OCD sample.
- Trial name
- NCT02797808
- Testing
- Sertraline, No Intervention
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obsessive-Compulsive Disorder
Function-metabolism Coupling in Decision-making Confidence Neural Network of Obsessive-compulsive Disorder
This study, a case-control study, aims to investigate the function-metabolism coupling in decision-making confidence neural network of obsessive-compulsive disorder.
- Trial name
- NCT05563935
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Obsessive-Compulsive Disorder
Translational Approach to the Understanding and Treatment of Obsessive-Compulsive Disorder (OCD). Can D-Cycloserine Enhance and Stabilize the Treatment-response in Relapsed and Non-responding OCD-patients?
In this randomized controlled trial (RCT) the investigators experimentally test if patients with Obsessive-Compulsive Disorder (OCD) who have received treatment with exposure and response prevention (ERP), but either relapsed or…
- Trial name
- NCT02656342
- Testing
- D-Cycloserine
- Where
- 14 sites in Norway
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
OCD
The Imaging Genetic Study of the Core Family of Obsessive-compulsive Disorder (OCD) Patient
To investigate the structural/functional abnormalities and the possible genetic endophenotypes of Obsessive-compulsive disorder (OCD) patients and their core families.
- Trial name
- NCT01298622
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kunming Medical University
Schizophrenia Disorders, Major Depression
Non-Coding RNAs Gene Expression in Psychiatric Disorders
This study aims to investigate whether specific non-coding RNAs, molecules involved in the regulation of gene expression, are altered in individuals with psychiatric disorders such as schizophrenia, bipolar disorder, major…
- Conditions
- Schizophrenia Disorders, Major Depression, Bipolar Affective Disorders, Obsessive Compulsive Disorder (OCD)
- Trial name
- PsiRNA26 (NCT07649993)
- Testing
- Reverse Transcription Quantitative Polymerase Chain Reaction
- Where
- 5 sites in Italy
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Carmen Concerto
Behavior, Depressive Disorder
Can Computational Measures of Task Performance Predict Psychiatric Symptoms and Changes in Symptom Severity Across Time
This study investigates the computational mechanisms associated with psychiatric disease dimensions. The study will characterize the relationship between computational parameter estimates of task performance and psychiatric…
- Conditions
- Behavior, Depressive Disorder, Anxiety Disorders, Obsessive Compulsive Disorder (OCD)
- Trial name
- CABxtime (NCT06705179)
- Testing
- Behavioral task performance
- Where
- 2 sites in United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- California Institute of Technology
Obsessive-Compulsive Disorder
Cognitive Training in Obsessive Compulsive Disorder
This unique study will allow us to observe the neural correlates associated with working memory in an obsessive compulsive disorder (OCD) paradigm.
- Trial name
- CTOCD (NCT02818088)
- Testing
- n-Back (Cognitive Training)
- Where
- South Africa
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Stellenbosch
Obsessive-Compulsive Disorder, Microbiota
Microbiome in Obsessive-compulsive Disorder
Background: Humans live in symbiosis with microbes and their implication for health and disease is evident. The importance of microbiome-gut-brain axis in psychiatric disorders is an area of increasing research interest.
- Trial name
- MIO (NCT03638791)
- Testing
- Exposure and response inhibition
- Where
- Sweden
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Obsessive-Compulsive Disorder, Cognitive Flexiblity
Cognitive Flexibility and Response to TMS Therapy
Transcranial Magnetic Stimulation (TMS) therapy is an approved and effective treatment option for treatment-resistant obsessive-compulsive disorder.
- Trial name
- CogFlexTMS (NCT06769243)
- Testing
- TMS
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative