Clinical trials: Obstetric Pain
Obstetric Pain, Labor Pain
Dural Puncture Epidural VS Standard Epidural on Physician Top-ups During Labour Analgesia
The purpose of this prospective randomized controlled study is to compare the number of physician top-up interventions during the first stage of labour between two different neuraxial analgesia techniques : the dural puncture…
- Conditions
- Obstetric Pain, Labor Pain, Anesthesia
- Trial name
- DPE (NCT04728048)
- Testing
- Dural puncture epidural, Standard epidural
- Where
- Canada
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Postpartum Pain, Opioid Stewardship
Implementing the COMFORT Guidelines for Postpartum Pain Management
A new national clinical practice guideline (CPG) for pain management after childbirth aims to mitigate peripartum opioid-related risks without compromising or exacerbating existing inequities in pain management in the United…
- Conditions
- Postpartum Pain, Opioid Stewardship, Maternity Care, Obstetric Care
- Trial name
- NCT06285123
- Testing
- REP, Facilitation
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Postoperative Pain, Obstetric Pain
Lidocaine Patches After Cesarean Section
The aim of this study is to investigate the impact of using lidocaine patches after cesarean section on pain control and opioid use in the immediate post-operative period.
- Conditions
- Postoperative Pain, Obstetric Pain, Opioid Use
- Trial name
- LPACS (NCT04443569)
- Testing
- Lidocaine patch
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Yale University
Pain, Procedural, Lidocaine
Effects of Cervical Lidocaine Spray on Pain Relief During Manual Vacuum Aspiration
This randomized control trial aim to evaluate the effectiveness of local lidocaine spray application to the cervix on the reducing of pain score during the manual vacuum aspiration
- Conditions
- Pain, Procedural, Lidocaine, Obstetric Surgical Procedures
- Trial name
- NCT06344637
- Testing
- 10 % lidocaine spray without adrenaline
- Where
- Thailand
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- UdonThani Hospital
Pain, Acute, Opioid Misuse
The Effect of a Charcoal Deactivation Pouch on Opioid Disposal After Cesarean Delivery
Background: There is scarce literature investigating how patients dispose of unused opioid supplies after their cesarean postoperative pain has faded.
- Conditions
- Pain, Acute, Opioid Misuse, Obstetric Pain, Cesarean Section Complications
- Trial name
- NCT05498025
- Testing
- Deterra activated charcoal pouch
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Obstetric Pain, Postpartum Depression
Ketamine to Improve Recovery After Cesarean Delivery - Part 1
The objective of this study is evaluate the breastmilk transfer and pharmacokinetics (Part 1) and effectiveness (Part 2) of a post-cesarean delivery intravenous ketamine bolus-and-infusion strategy, as a preventive analgesic…
- Conditions
- Obstetric Pain, Postpartum Depression, Breastfeeding, Pain, Acute
- Trial name
- KINETIC (NCT04037085)
- Testing
- Ketamine
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Labor Complication, Midwife
Effect of Intrapartum Continuous Midwife Support on Maternal and Neonatal Stress Level
This study aims to provide strong A-level evidence to the literature by supporting the maternal and fetal results of continuous midwife support together with saliva cortisol level measurements.
- Conditions
- Labor Complication, Midwife, Stress, Labor Pain
- Trial name
- NCT05302401
- Testing
- intrapartum uninterrupted midwife support
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Marmara University
Obstetric Pain, Pain
Virtual Reality in Obstetric Patients
The purpose of this study is to determine if non-invasive distracting devices (Virtual Reality headset) are more effective than the standard of care (i.e., no technology based distraction) for preventing anxiety and pain scores…
- Trial name
- NCT03495531
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stanford University
Epidural, Labor Pain
Improving Labour Induction Analgesia: Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour
Labour pain can be intensified for labour inductions and women undergoing inductions often have earlier and more frequent requests for analgesia.
- Conditions
- Epidural, Labor Pain, Induction of Labor Affected Fetus / Newborn, Obstetric Anesthesia Problems
- Trial name
- NCT04011098
- Testing
- Epidural Fentanyl Bolus, Standard Epidural Group
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Labor Pain, Early Labor
Therapeutic Rest to Delay Admission in Early Labor: A Prospective Study on Morphine Sleep
This will be a prospective study on labor characteristics, and obstetric and neonatal outcomes in women who accept and women who decline morphine as a form of pain management in labor.
- Trial name
- NCT03539562
- Testing
- Morphine Sulfate and Promethazine
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Childbirth Experience, Urinary Retention
Analgesia in the Second Stage of Labour
This study investigates efficacy, safety and childbirth experience in women receiving pudendal block during the final stage of delivery. It is an observational study and half of included primarous women recieve a pudendal block.
- Conditions
- Childbirth Experience, Urinary Retention, Satisfaction, Personal, Pain, Obstetric
- Trial name
- ASL (NCT04391075)
- Testing
- Pudendal nerve block
- Volunteers
- 1,007 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Labor Pain, Obstetric Pain
Association Between Bolus Rate and the Adequacy of Labor Analgesia Using Timed-intermittent Boluses
Administration of anesthetic solution into the epidural space is usually accomplished by a combination of continuous infusion, provider-administered boluses and patient-administered boluses (patient controlled epidural analgesia…
- Trial name
- NCT02340806
- Testing
- CADD-Solis pump (Smiths Medical)
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pain, Obstetric
Efficacy of Extended-Release Liposomal Bupivacaine for Post-Partum Pain Management Following Obstetrical Laceration
We propose a prospective, randomized, single blinded trial with subjects recruited from the WRNMMC Labor and Delivery Unit to study post-partum efficacy of Exparel® for pain control in patients undergoing a vaginal delivery who…
- Trial name
- NCT03152877
- Testing
- Bupivacaine Liposome Injectable Product, 0.25% plain bupivacaine
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Obstetric Pain
Ropivacaine Continuous Wound Infusion Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Delivery
Cesarean delivery is one of the most common surgical procedures, performed at an increasingly high rate. It is associated with intense postoperative pain that may hamper the rehabilitation process and interfere with patient…
- Trial name
- NCT03502642
- Testing
- wound infusion (Dosi-Pain® Kit, LEVENTON SAU, Spain), Spinal Anesthesia, intrathecal morphine
- Where
- Lebanon
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Obstetric Pain
The Effect of the Transversus Abdominis Plane Block to Postoperative Analgesia for Cesarean Section
The transversus abdominis plane block (TAP block) has effect to postoperative analgesia for cesarean section with spinal anesthesia but it was limited for cesarean section with general anesthesia.
- Trial name
- TAP (NCT03634111)
- Testing
- TAP block, Morphine, Ropivacaine
- Where
- Vietnam
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gia Dinh People Hospital
Obstetric Pain
Effect of Preemptive Epidural Analgesia in Labor on Cytokine Production
During labor there is an increased production of inflammatory mediators called cytokines. Higher concentration of certain cytokines has been linked to adverse neonatal and maternal outcomes.
- Trial name
- NCT00361712
- Testing
- Preemptive epidural analgesia, Standard of care
- Where
- Israel
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Labor Complication, Labor Pain
Wide Use of Paperless Partograph in Evaluation of Labour
Paperless partograph wide using in labour room as simple tool in evaluation of labour
- Trial name
- labourRecord (NCT03276117)
- Where
- 6 sites in Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Labor Pain, Obstetric Pain
ANSiStim Study for Active Labor Pain
The specific aim of the study is to do comparison between ANSiStim and Placebo for pain relief in labor. During the treatment, pain relief will be assesed with ANSiStim in active labor through continues checking of VAS SCORE.
- Trial name
- ANSS-ALP (NCT02427139)
- Testing
- ANSiStim
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- DyAnsys, Inc.
Pregnancy, Obstetric Labor
Effects of Digital Vaginal Examination During Labor on Pain and Anxiety Levels
Digital vaginal examination is the most common method for assessing progress of labor and delivery. Considering it is the most common intervention women receive during course of labor, evidence for psychological effects of…
- Trial name
- NCT02599610
- Testing
- Digital vaginal examination, Transperineal ultrasound examination
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ankara University