Clinical trials: Obstetrics
Blood Loss Massive, Post Operative Hemorrhage
Evaluation of the Quantra QStat System in Obstetric Patients
This pilot study will assess the performance of the Quantra System with the QStat Cartridge versus standard of care coagulation testing in bleeding pregnant women at delivery.
- Trial name
- NCT05875987
- Testing
- Quantra System
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- HemoSonics LLC
Recurrent Miscarriage
Obstetrics , Prenatal Outcomes in Recurrent Miscarriage
The effect of recurrent miscarriage on the outcome of the current pregnancy and if there's a relation between it and adverse out come
- Trial name
- OBPORPL (NCT06356792)
- Where
- Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Assiut University
Sudden Unexplained Infant Death, Apnea of Newborn
Advanced Wireless Sensors for Neonatal Care in the Delivery Room
The goals of this observational study is to assess whether a new advanced wireless skin sensor vital sign monitoring system can effectively monitor the vital signs of healthy newborn infants (≥ 35 weeks gestational age).
- Conditions
- Sudden Unexplained Infant Death, Apnea of Newborn, Newborn Morbidity, Newborn Asphyxia
- Trial name
- AWARD (NCT06693817)
- Testing
- Wireless skin sensors vital sign monitoring system, Wired vital sign monitoring system
- Where
- 5 sites in Brazil, Canada and 2 more
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Guilherme Sant'Anna, MD
Inflammatory Response, Abortion, Habitual
Explore the Role of NLRP7 in the Regulation of Progestereone Induced Decidualization of Human Endometrial Stroma Cells
The investigators have found that NLRP7 was upregulated and nuclear translocated in an in vitro model of decidualization. Knock-down or overexpression of NLRP7 reduced or enhanced the expression of decidual marker IGFBP-1.
- Trial name
- NCT04148638
- Where
- Taiwan
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Pain, Postoperative, Opioid Use
Stopping Opioid Overuse in Obstetrics to Halt Exposure Trial
As the opioid epidemic continues on, more research is needed on multi-modal approaches to decrease opioid exposure after common procedures.
- Trial name
- SOOOTHE (NCT04680221)
- Testing
- Liposomal bupivacaine, TAP block, Deposition of saline
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
No Placental Abruption, No Hemorrhage
Proof of Concept Study of a Sucker Hemostatic Intra Uterine in Postpartum Hemorrhage After Abruptio Placenta Assisted
The postpartum hemorrhage (PPH) is the major complication of the delivery. In clinical practice, if after giving birth, the placenta is not expelled naturally, an active management should be triggered.
- Trial name
- HEMOGYN (NCT01589744)
- Testing
- Suction cup Hemostatic Intra-Uterine, device not marked CE (not marketed)
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- AdministrateurCIC
Hereditary Cancer Syndrome
Feasibility Trial of Combination of Obstetrical Carrier Screening and Hereditary Cancer Screening
The investigators hypothesize that preconception and pregnancy may be a feasible and effective time to offer inherited cancer risk screening.
- Trial name
- FOCUS (NCT07195071)
- Testing
- Natera empower comprehensive hereditary cancer panel, Obstetrical carrier screening
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Post Spinal Shivering
Compair Efficacy of iv Dexmedetomidine & Tramadol for Post Spinal Shivering in Obs Patients Undergoing Cesarean Section
When opposed to GA,SA is recommended during c section. Shivering is more prevalent and inconvenient complication of spinal anaesthesia, with 40 to 70% incidence rate.
- Trial name
- NCT05616364
- Testing
- Dexmedetomidine injection, Tramadol
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sana Bahadur
Labor and Childbirth, Labor (Obstetrics)--Complications
Development of a Multidimensional Predictive Model of Dystocic Labor. Association of Physical Condition and Psychosocial Factors With the Birth Process and Breastfeeding Success.
The goal of this observational study is to learn how a pregnant woman's physical fitness and emotional well-being can help predict the type of birth she will have (such as a natural vaginal birth versus a cesarean section or a…
- Conditions
- Labor and Childbirth, Labor (Obstetrics)--Complications, Hand Strength, Physical Conditioning, Human
- Trial name
- MPM-PD (NCT07635771)
- Where
- Spain
- Volunteers
- 420 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Termination of Pregnancy
Obstetric & Pediatric Evolution Following Parental Refusal for Early Termination of Pregnancy Despite Fetal Risk
More and more parents decide to maintain pregnancy which could have been interrupted because of serious fetal pathologies. In this observational study, the investigators examine obstetrical and pediatric evolution of these…
- Trial name
- NCT03393455
- Testing
- not accurate
- Where
- France
- Volunteers
- 211 people
- Sponsor
- University Hospital, Montpellier
Birth Injuries, Obstetric; Injury
Muscle Viscoelastic Properties In Birth Palsy
The aim of study was to observe changes in denervated muscles viscoelastic properties and motor performance of OBPP children. Viscoelastic properties have a significant effect on muscle performance; however have not investigated…
- Trial name
- Birth Palsy (NCT04148131)
- Volunteers
- 74 people
- Sponsor
- Hacettepe University
Refugee, Asylum-seeking Women
Maternity Care Experiences of Asylum-seeking and Refugee Women in Scotland
The International Organisation of Migration reports that over half (52.4%) of international migrants in Europe are women. Evidence suggests that women with immigrant backgrounds often struggle to access healthcare across the…
- Conditions
- Refugee, Asylum-seeking Women, Maternity
- Trial name
- MACAWS (NCT06354751)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Aberdeen
Obstetric Labor Complications
MRI Pseudo-CT Sequences for Obstetrical Pelvimetry.
It is possible to perform a pelvimetry by MRI as a substitute to pelvimetry by CT, hence sparing the patient from a dose of irradiation.
- Trial name
- Pelvi-MRI (NCT06485323)
- Testing
- MRI pelvimetry
- Where
- Belgium
- Volunteers
- 95 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Medical Education, Normal Vaginal Delivery
Virtual Reality Birth Simulator
The investigators compared an in-house developed virtual reality simulator for normal vaginal deliveries with a legacy mannequin-based simulation in a cluster randomised study involving Year 4 medical students undergoing their…
- Conditions
- Medical Education, Normal Vaginal Delivery, Simulation Training, Virtual Reality
- Trial name
- ViVaDeX (NCT06653270)
- Testing
- Virtual reality simulator, Mannequin-based simulator
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Obstetrics for C/S
The Relationship of Abdominal Circumference and Trunk Length With the Level of Spinal Anesthesia in Obstetric Patients
The body shape might have influence on the spinal level. In this research we plan to investigate the relationship of abdominal circumference, trunk length and the level of spinal anesthesia in obstetric patients during Cesarean…
- Trial name
- NCT00748176
- Testing
- spinal anesthesia
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Absent End-Diastolic Flow Of The Fetal Umbilical Artery
Clinical Significance Of Intermittently Absent End-Diastolic Flow Of The Fetal Umbilical Artery On Perinatal And Neonatal Outcomes Dr. Zeynep Kayaoğlu Yıldırım Dr. Alperen İnce Dr Gökhan Bayanmelek Dr Gökhan Bolluk
Objective: This study aimed to estimate the risk of adverse perinatal outcomes among pregnant patients with intermittently absent (iAEDF) and persistently absent end-diastolic umbilical artery flow (pAEDF).
- Trial name
- NCT06346327
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Caesarean, Training
FAUCS Surgery: Learning Curve for Resident
In the last decades, caesarean section (CS) rates are getting higher in all over the world. This encourages us to improve operative techniques.
- Trial name
- NCT04155177
- Testing
- training for french ambulatory caesarean section
- Where
- Tunisia
- Sponsor
- University Tunis El Manar
To Compare 2 Models of Midwifery Care in Maternity Care
Support and Personalized Care in Alternative Midwifery Birth Units Versus Traditional Units in France: Effects on the Psychological Health of Couples and on the Health of the Mother and Child at the Age of 2 Years.
Majority of pregnancies and childbirths in France occur without complication. While the impact of care failure on maternal and neonatal morbi-mortality is now well- established, the literature reveals that an overmedicalization…
- Trial name
- PhysioCareTwo (NCT06630741)
- Testing
- alternative midwifery units (AMU)
- Where
- 3 sites in France
- Volunteers
- 793 people
- Sponsor
- Rennes University Hospital
Bladder Injury, Complications; Cesarean Section
Cystoinflation to Prevent Bladder Injury in Obstetrics and Gynaecology Surgery
Part1:The healthy pregnant women with previous operative deliveries admitted for elective C-section will be counselled and conditioned informed consent will be taken to be included in either study group if dense pelvic adhesions…
- Conditions
- Bladder Injury, Complications; Cesarean Section, Adhesions Pelvic
- Trial name
- NCT04302545
- Testing
- Cystoinflation
- Where
- Pakistan
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- Shazia Saaqib
Morning Sickness
Freezie Remedy to Alleviate Morning Sickness
The primary objective of this study is to assess the effectiveness of Lillipops in the improvement of morning sickness symptoms.
- Trial name
- NCT01668940
- Testing
- Lillipops Iced Soothies (4 flavours), Mr. Freeze Freezies, Lillipop Iced Soothies (Ginger flavour)
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children