Clinical trials: Obstructed Defecation
Obstructed Defecation Syndrome (ODS)
Effects of Botox in Obstructed Defecation Syndrome
The purpose of this study is to determine if Botulinum Toxin-A (Botox) injection will improve symptoms of constipation in obstructed defecation syndrome (ODS).
- Trial name
- NCT02160288
- Testing
- Botulinum Toxin-A, Normal Saline
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Massachusetts General Hospital
Constipation, Impaction, and Bowel Obstruction, TAMIS Mucosectomy
Outcome of TAMIS Mucosal Resection in Patients With ODS
Patients, aged 18 - 90 years, undergoing TAMIS mucosectomy at the Department of General Surgery at the Medical University of Vienna are enrolled into our study.
- Conditions
- Constipation, Impaction, and Bowel Obstruction, TAMIS Mucosectomy, Obstructed Defecation Syndrome
- Trial name
- NCT06522399
- Testing
- TAMIS mucosectomy
- Where
- Austria
- Volunteers
- 11 people
- Sponsor
- Medical University of Vienna
Rectal Prolapse, Rectocele
Long Term Results of STARR With Contour Transtar
Obstructed defecation syndrome (ODS) is a widespread and disabling syndrome. With this study the investigators want to evaluate the long term results of Stapled Transanal Rectal Resection (STARR) performed with Contour Transtar…
- Conditions
- Rectal Prolapse, Rectocele, Intussusception of Rectum
- Trial name
- LTSTARR (NCT02971332)
- Testing
- Stapled Transanal Rectal Resection
- Volunteers
- 113 people
- Sponsor
- University of Roma La Sapienza
Obstructive Defecation Syndrome, Outlet Obstruction
Dynamic MRI Evaluation Post Operative Stapled Trans Anal Rectal Resection (STARR) Procedure
The purpose of this study is to assess the effects of the Stapled Trans Anal Rectal Resection (STARR) procedure for patients with obstructive defecation syndrome.
- Trial name
- NCT00655382
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Obstructed Defecation, Anismus
Comparative Study Between Surgical and Non Surgical Treatment of Anismus in Patients
Comparative study between surgical and non surgical treatment of anismus in patients with symptoms of obstructed defecation. Anismus is a significant cause of chronic constipation.
- Conditions
- Obstructed Defecation, Anismus, Constipation
- Trial name
- NCT00735605
- Testing
- BFD, PDPR, BTX A
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Dyssenergic Defecation, Straining, Hard Stools, Incomplete Evacuation
Biofeedback for Women With Dyssynergic Defecation (DD)
This research aimed to compare the effect of Biofeedback (BFB) versus Lifestyle management in form of stretching positions and patient's education position of defecation, in addition to rectal massage, and anal dilators among…
- Trial name
- DD (NCT07622732)
- Testing
- Lifestyle management in form of stretching positions and patient's education position of defecation
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Ahram Canadian University
Constipation, Incontinence
Psyllium Fiber Versus Placebo in Early Treatment After STARR for Obstructed Defecation: a Double-blind RCT
This study aims to assess whether fiber intake, formerly recommended only before or instead of surgery, may play a role in improving postoperative progress and functional outcome after STARR for obstructed defecation, in terms of…
- Trial name
- NCT02136693
- Testing
- Psyllium fiber
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- Francesco Gabrielli
Rectal Prolapse, Defecation Disorder
Rectal Prolapse With ODS. STARR vs LVR.
The objective of the study will be to evaluate the clinical and functional outcome of patients with obstructed defecation sndrome (ODS) associated to internal rectal prolapse, treated with transanal prolassectomy (STARR) surgery…
- Conditions
- Rectal Prolapse, Defecation Disorder, Rectocele; Female, Surgery
- Trial name
- NCT04892108
- Testing
- STARR (Stapled Trans Anal Rectal Resection), LVR (Laparoscopic Ventral Rectopexy)
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University Hospital of Ferrara
Constipation by Outlet Obstruction
Defecation Patterns in Constipated Patients
Chronic constipation (CC) is a common condition that affects up to 25% of the population in North America. It poses a major burden on the healthcare cost.
- Trial name
- NCT04903470
- Testing
- Bisacodyl, Atropin
- Where
- 2 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- The California Medical Innovations Institute, Inc.
Perineal Descent, Obstructed Defecation Syndrome (ODS)
Clinical Evaluation of the Femiset Device for Perineal Descent in Women
The University of Antwerp developed a device (Femiset) to alleviate defecation difficulties in women suffering from Descending Perineum Syndrome (DPS).
- Trial name
- FEMISET (NCT07039188)
- Testing
- Use device in home environment
- Volunteers
- 20 people
- Sponsor
- University Hospital, Antwerp
Obstructed Defaecation Syndrome, Anterior Rectocele
Rectocele Repair with or Without Internal Sphincter Botulinum Toxin Injection: a Prospective Randomized Trial
This is a single-centre, prospective randomized controlled trial on female patients with anterior rectocele associated with obstructed defecation syndrome
- Trial name
- NCT06804993
- Testing
- Transvaginal repair & botulinum toxin type A injection, Transvaginal repair & distilled water injection
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Obstructed Defecation Syndrome (ODS)
Stapled TransAnal Rectal Resection (STARR): Clinical and Radiological Outcome
To evaluate the correlation between clinical and radiological outcome after Stapled TransAnal Rectal Resection (STARR)
- Trial name
- NCT00587080
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- University of Zurich
Constipation
International Multicenter Prospective Transtar Registry
Obstructed Defecation Syndrome (ODS) describes a condition which is characterized by chronic constipation. The symptoms of ODS include abdominal pain or cramping, irregular bowel frequency and the feeling of not having emptied…
- Trial name
- NCT00909116
- Testing
- Stapled Transanal Rectal Resection with Contour Transtar
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Ethicon Endo-Surgery (Europe) GmbH
Obstructive Defecation Syndrome, Chronic Constipation
Study of Stapled Transanal Rectal Resection (STARR) Surgery in Refractory Constipation Associated With Obstructive Defecation Syndrome (ODS)
The primary purpose of this study is to determine how effective and how durable STARR (stapled transanal rectal resection) surgery is in relieving symptoms of intractable constipation associated with obstructive defecation…
- Conditions
- Obstructive Defecation Syndrome, Chronic Constipation, Rectocele, Intussusception
- Trial name
- NCT00256984
- Testing
- Stapled Transanal Resection (STARR) with Transtar (PROXIMATE®) 33 mm Circular Stapler
- Where
- 7 sites in United States
- Volunteers
- 75 people
- Sponsor
- Ethicon Endo-Surgery
Obstructed Defecation, Pelvic Organ Prolapse
Prospective Randomized Controlled Trial of Obstructed Defecation Surgery
Obstructive defecatory syndrome (ODS) or inability to completely empty bowel is characterized by a combination of straining, incomplete evacuation, and the use of digital manipulation with bowel movement.
- Trial name
- PROD (NCT05747027)
- Testing
- Laparoscopic abdominal ventral rectopexy, Transvaginal sacrospinous rectopexy
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Endeavor Health
Rectal Prolapse
Laparoscopic Rectopexy for Rectal Prolapse
The aim of the present prospective, double-blind, randomized study is to study whether laparoscopic anterior mesh rectopexy is as good as laparoscopic posterior rectopexy with respect to obstructive defecation afterwards.
- Trial name
- NCT00946205
- Testing
- Laparoscopic posterior rectopexy, Laparoscopic anterior mesh rectopexy
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- Aarhus University Hospital
Vaginal Prolapse
Sacrocolpopexy With Posterior Repair Obstructed Defecation Symptoms
Participants who undergo laparoscopic sacrocolpopexy (LSCP) plus posterior repair (PR) will demonstrate greater improvement bowel symptom scores compared to participants who undergo LSCP alone at 3 months postoperatively.
- Trial name
- NCT03658395
- Testing
- Laparoscopic Sacrocolopopexy, Posterior repair
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Oklahoma
Surgery, Obstructive Defecation Syndrome
Mental Health Outcome After Surgery for Obstructed Defecation Syndrome (ODS)
Background: Obstructed Defecation Synsdrome (ODS) causes people to strain and sometimes need help to go to the toilet. They think about going to the toilet a lot, which makes their lives worse.
- Conditions
- Surgery, Obstructive Defecation Syndrome, Mental Health Issue, Depression/Anxiety
- Trial name
- MentODSSurg (NCT06502184)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Evangelisches Klinikum Köln Weyertal gGmbH
Rectal Prolapse
What Benefit With a New Stapler Device in the Surgical Treatment of Obstructed Defecation?
This randomized study was designed to compare the 2 year clinical and functional results with the STARR procedure using a new curved cutter stapler or the same operation done with 2 traditional circular staplers.
- Trial name
- NCT00810745
- Testing
- starr
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- University of Milan
Obstructed Defecation
Obesity on the Efficacy of Bilateral Tibial Nerve Stimulation
Obstructed defecation syndrome (ODS) is a common functional bowel disorder characterized by difficulty in stool evacuation. Bilateral posterior tibial nerve stimulation (BT PTNS) has emerged as a noninvasive, safe, and effective…
- Trial name
- NCT07390682
- Testing
- Bilateral posterior tibial nerve stimulation
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt