Clinical trials: Obstruction
Coronary Artery Disease
Drug-Eluting Stent Implantation Versus Optimal Medical Treatment in Patients With Chronic Total Occlusion (DECISION-CTO)
The purpose of this study is to compare the safety and effectiveness of drug-eluting stent implantation compared to optimal medical treatment in patients with chronic total occlusion.
- Trial name
- NCT01078051
- Testing
- Cypher, xience, Endeavor, Taxus, optimal medical therapy
- Where
- 26 sites in India, Indonesia and 3 more
- Volunteers
- 840 people
- Sponsor
- Seung-Jung Park
Intubation Complication
Factors Associated With Occluding the Upper Esophagus by Paratracheal Force
We aim to identify anatomical factors that affect upper esophageal occlusion during the application of paratracheal pressure.
- Trial name
- NCT06210867
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- SMG-SNU Boramae Medical Center
Gastric Outlet Obstruction
ComVi and D-type Stent in Malignant GOO
Covered self-expandable metallic stents (SEMS) have been used to prevent tumor ingrowth, a common complication of uncovered SEMSs.
- Trial name
- NCT01839292
- Testing
- uncovered D-type stent insertion, double-layered ComVi stent insertion
- Where
- South Korea
- Volunteers
- 89 people
- Sponsor
- Ajou University School of Medicine
Total Hip Surgery, Pericapsular Nerve
PENG vs. QLB vs. Lumbar ESPB in Total Hip Surgery
The aim of this study is to compare between Pericapsular Nerve Group Block, Erector Spinae Plane Block and Quadratus Lumborum Block for managing acute postoperative pain in patients undergoing total hip surgeries under spinal…
- Conditions
- Total Hip Surgery, Pericapsular Nerve, Quadratus Lumborum, ESPB
- Trial name
- NCT05600244
- Testing
- PENG block Technique, Lumbar ESPB Technique, Transmuscular QLB-t block Technique
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Retinal Vein Occlusion
To Study the Effectiveness and Safety of Niacin and a Topical Steroid Eye Drop to Treat Retinal Vein Occlusions
The purpose of this study is to determine whether Niacin, a B vitamin, may act as a vasodilator to encourage earlier formation of collateral blood vessels that may serve to bypass the obstructed vein in the eye.
- Trial name
- NCT00493064
- Testing
- Nicotinic acid, Prednisolone acetate
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Palo Alto Medical Foundation
Gastric Ulcer With Perforation But Without Obstruction, Colon Cancer
Domestic Surgical Robot Clinical Study
Central South University in collaboration with Tianjin University developed the first domestically produced Chinese minimally invasive surgical (MIS) robot system which named "Micro Hand S" in 2013.
- Conditions
- Gastric Ulcer With Perforation But Without Obstruction, Colon Cancer, Cholecystolithiasis, Appendicitis
- Trial name
- NCT02752698
- Testing
- Micro Hand S robotic surgery, laparoscopic surgery, da Vinci robotic surgery
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Arthroplasty, Replacement, Knee
Fast Track Total Knee Arthroplasty: Local Infiltration Analgesia vs Femoral Nerve Block
The objective of this study is to determine whether either a femoral nerve block (FNB) or local infiltration analgesia (LIA) is a better anesthetic technique to achieve optimal functional outcome after one year in patients…
- Trial name
- NCT01966263
- Testing
- LIA of the posterior capsule of the knee, LIA of the anterior capsule of the knee, LIA of the subcutaneous tissue of the knee
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- Sint Maartenskliniek
Postoperative Pain, Complications
A Trial of Closed Hemorrhoidectomy Under Local Perianal Block Versus Spinal Anesthesia
Hemorrhoidectomy can be carried out under several modes of anesthesia. In western country hemorrhoidectomy usually be performed under general anesthesia, however there may be the complications resulted from general anesthesia…
- Conditions
- Postoperative Pain, Complications, Satisfaction
- Trial name
- NCT00925912
- Testing
- spinal block, Perianal block
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Aortic Stenosis, Aortic Insufficiency
Freedom SOLO Stentless Heart Valve Study
The purpose of this clinical investigation is to demonstrate the safety and effectiveness of the Freedom SOLO heart valve.
- Trial name
- SOLO (NCT01115907)
- Testing
- Freedom SOLO Stentless Heart Valve
- Where
- 15 sites in United States, Canada
- Volunteers
- 251 people
- Sponsor
- Sorin Group USA, Inc.
Pain, Total Knee Arthroplasty
Duration of Leg Nerve Blocks With Dexamethasone Added to Local Anesthetic
This is a Randomized Double blinded controlled trial on the effect of adding dexamethasone to Ropivacaine on the duration of pain relief for ultrasound guided femoral, obturator and popliteal block after total knee replacement…
- Trial name
- NCT01511211
- Testing
- Dexamethasone, Ropivacaine
- Where
- United States
- Sponsor
- University of New Mexico
Postoperative Residual Curarization, Neuromuscular Block
Reversal With Low Doses of Sugammadex in Patients Undergoing Non-cardiac Surgery
Neuromuscular blocking agents (NMBA) are among the most commonly used drugs during general anesthesia and may induce complete muscle paralysis.They are used clinically to facilitate endotracheal intubation and to optimize…
- Trial name
- NCT03460509
- Testing
- Sugammadex
- Volunteers
- 144 people
- Sponsor
- The Hospital of Vestfold
Kidney Calculi
Paravertebral Block Versus Epidural Anesthesia for Percutaneous Nephrolithotomy
This prospective, randomized study is aimed to assess the efficacy and safety of paravertebral block compared to epidural anesthesia for percutaneous nephrolithotomy.
- Trial name
- PVB (NCT03018899)
- Testing
- paravertebral block, epidural anesthesia
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Huazhong University of Science and Technology
External Oblique and Rectus Abdominis Plane Block, Quadratus Lumborum Block
External Oblique and Rectus Abdominis Plane Block Versus Quadratus Lumborum Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy
This study aims to compare the effects of the external oblique and rectus abdominis plane (EXORA) block and the quadratus lumborum block (QLB) on postoperative analgesia in patients undergoing laparoscopic cholecystectomy (LC).
- Conditions
- External Oblique and Rectus Abdominis Plane Block, Quadratus Lumborum Block, Postoperative Analgesia, Laparoscopic Cholecystectomy
- Trial name
- NCT07082387
- Testing
- External oblique and rectus abdominis plane block, Quadratus lumborum block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Effect Increased
Can Latency of Action in Infraclavicular Brachial Plexus Block be Shortened With Warmed Bupivacaine?
Brachial plexus blocks have some advantages, but also have some disadvantages as well. As with all nerve blocks, having to wait sometime for an effective block, sometimes failure to achieve an adequate block and possible…
- Trial name
- NCT03346993
- Testing
- Bupivacaine Hydrochloride 5 MG/ML
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Erzurum Palandöken State Hospital
Cardiovascular Diseases
ESPB vs TPVB for Cardiac Surgery
Pain is a common and serious problem after cardiovascular surgery. It is associated with increased morbidity and mortality, and additional risk factors of cardiac surgery such as sternotomy and cardiopulmonary bypass contribute…
- Trial name
- NCT05476393
- Testing
- Postoperative management
- Where
- Turkey (Türkiye)
- Sponsor
- Medipol University
Atrial Fibrillation
Intracardiac Versus Transesophageal Echocardiography for Left Atrial Appendage Occlusion Combined With Radiofrequency Ablation
A total of 60 patients with atrial fibrillation were scheduled to receive left atrial appendage occlusion combined with radiofrequency ablation, which were divided into two groups.
- Trial name
- NCT04391504
- Testing
- LAAC combined with radiofrequency ablation group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Ruiqin xie
Acute Malignant Colonic Obstruction, Colorectal Cancer
Colonic Stenting With Elective Surgery Versus Emergency Surgery in the Management of Acute Malignant Colonic Obstruction
The use of colonic stenting with elective surgery has been suggested as an alternative management for acute malignant colonic obstruction, as emergency surgery has a high risk of morbidity and mortality.
- Conditions
- Acute Malignant Colonic Obstruction, Colorectal Cancer, Colonic Obstruction
- Trial name
- NCT01997684
- Testing
- Colonic Stenting with Elective Surgery, Emergency Surgery
- Where
- 9 sites in China
- Volunteers
- 200 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Congenital Diaphragmatic Hernia
Smart Removal for Congenital Diaphragmatic Hernia
The purpose of this study is to demonstrate the ability to prenatally deflate and to evaluate the safety of the Smart-TO device for fetoscopic endoluminal tracheal occlusion (FETO) in fetuses with congenital diaphragmatic hernia…
- Trial name
- SmartRemoval (NCT05100693)
- Testing
- Fetoscopic Endoluminal Tracheal Occlusion with the Smart-TO Balloon
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Iliac Vein Obstruction, May-Thurner Syndrome
Vascular Ultrasound Versus Intravascular Ultrasound for Diagnosing Iliac Vein Obstruction
Determine the sensitivity, specificity and accuracy of vascular ultrasound, using direct and indirect ultrasonographic signs, in the obstructive diseases of iliac venous segment, in patients with advanced chronic venous…
- Conditions
- Iliac Vein Obstruction, May-Thurner Syndrome, Cockett Syndrome
- Trial name
- USG-DIVO (NCT02240914)
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Fabio H Rossi
Healthy Volunteers
Physiology of Volition Studied With Nerve Block
Background: The experience of volition that accompanies voluntary movement can be divided into the sense of will, or deciding to move, and the sense of agency, or feeling that the movement just made was self-generated.
- Trial name
- NCT01143506
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
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