Clinical trials: Obstructive Chronic Pulmonary Disease
Pulmonary Disease, Chronic Obstructive, Mitochondrial Alteration
High Intensity Interval Training and Muscle Adaptations During PR
Pulmonary rehabilitation (PR) is a validated treatment in patients with Chronic Obstructive Pulmonary Disease (COPD), improving exercise tolerance, quality of life and dyspnea.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Mitochondrial Alteration, Oxygen Deficiency
- Trial name
- MITOXITRAIN (NCT05858463)
- Testing
- Modality of exercise training
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pulmonary Disease, Chronic Obstructive
Chronic Obstructive Pulmonary Disease (COPD)-Related Outcomes and Costs for Patients on Combination Fluticasone Propionate-Salmeterol Xinafoate 250/50mcg Versus Anticholinergics in a COPD-Comorbid Depression/Anxiety Population
The objective of this study was to examine COPD-related outcomes for patients with comorbid depression/anxiety who are on combination fluticasone propionate/salmeterol xinafoate compared to those receiving anticholinergics.
- Trial name
- NCT01337336
- Testing
- fluticasone propionate/salmeterol xinafoate, Anticholinergics
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Diaphragm Electrical Activity, COPD (Chronic Obstructive Pulmonary Disease)
Effect of Electrical Diaphragmatic Stimulation on Chronic Obstructive Pulmonary Disease
Respiratory muscle dysfunction is a common consequence of chronic obstructive pulmonary disease (COPD). This technique consists of placing electrodes on the skin at locations near the motor points of the diaphragm, transmitting…
- Trial name
- NCT07020299
- Testing
- Device : Digital electrical muscle stimulator is applied to induce diaphragm contraction.
- Where
- Egypt
- Volunteers
- 128 people
- Sponsor
- Mansoura University Hospital
Pulmonary Disease, COPD
Reducing Dynamic Hyperinflation Through Breathing Retraining
This study will compare the effects of exercise training and breathing retraining (using metronome tones) to exercise training only. Exercise training lasts 12 weeks.
- Trial name
- NCT01009099
- Testing
- breathing retraining, exercise training
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- US Department of Veterans Affairs
Asthma (Diagnosis)
Chronic Effects of Photobiomodulation With an LED Vest on Functional Capacity, Inflammatory Markers, and Muscle Perfusion in Children With Asthma
Asthma is a chronic inflammatory disease of the airways that results in tissue remodeling, airflow limitation, and bronchial hyperresponsiveness.
- Trial name
- Asthma PBM (NCT07613671)
- Testing
- Photobiomodulation, Exercise
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Nove de Julho
COPD
Effect of Rehabilitation at Moderate Altitude on Airway Resistance Measured With Forced Oscillation Technique in COPD-patients
Airway resistance will be measured using the forced oscillation technique (FOT). The parameters Rrs, Xrs, and ∆Xrs will be compared before and after a pulmonary rehabilitation cycle at moderate altitude.
- Trial name
- NCT07063563
- Testing
- ambiant air, Oxygen
- Where
- 2 sites in Kyrgyzstan, Switzerland
- Volunteers
- 52 people
- Sponsor
- Eastern Switzerland University of Applied Sciences
Asthma, COPD
Inhaler Technique in Elderly Patients: Impact on Disease Exacerbations
Introduction COPD and Asthma affect more than 10% of the population. Most patients use their inhaler incorrectly, mainly the elderly, thereby becoming more susceptible to poor clinical control and exacerbations.
- Trial name
- NCT03449316
- Testing
- Inhaler technique education
- Volunteers
- 146 people
- Sponsor
- Aveiro-Aradas Family Health Unit
Mechanically Ventilated Patients
Nebulized Heparin and Salbutamol in Mechanically Ventilated Patients With AECOPD
This randomised study was designed to assess the efficacy of nebulised heparin and salbutamol in improving lung function in mechanically ventilated patients with AECOPD.
- Trial name
- NCT03333395
- Testing
- Nebulized heparin and salbutamol, Nebulized salbutamol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Pulmonary Disease, Chronic Obstructive
Evaluation of the Role of Nocturnal Non-Invasive Ventilation in Pulmonary Rehabilitation
Hypothesis: Hospital based, comprehensive pulmonary rehabilitation of patients with COPD in GOLD stage IV can be optimized by application of nocturnal non invasive ventilation.
- Trial name
- NCT00710463
- Testing
- non invasive ventilation (Resmed VPAP III ST-A, Respironics Harmony)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Deutsche Lungenstiftung e.V.
COPD
Effects of Combined Cognitive Rehabilitation in COPD Patients
This study was to examine the effect of endurance training combined with cognitive training in patients with COPD. The intervention group underwent Cognitive Training added to Endurance Training and the control group underwent…
- Trial name
- NCT03907839
- Testing
- clinical trials
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculty of Medicine, Sousse
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive
Is the Short Physical Performance Battery a Useful Outcome Measure in Chronic Obstructive Pulmonary Disease
Patients with Chronic Obstructive Lung Disease (COPD) often develop muscle problems, particularly in their legs which makes them more limited in what they can do.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive, Pulmonary Emphysema, Bronchitis, Chronic
- Trial name
- NCT01515709
- Where
- United Kingdom
- Volunteers
- 445 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Asthma-COPD Overlap Syndrome
This Study Include Asthma Chronic Obstructive Pulmonary Disease (COPD) Overlap Patients.Patients Were Vitamin D Deficient.Age Range 40-70 Years, Smokers.Patients Were Advised to Take Either Placebo or Vitamin D3.Lung Functions and Exercise Tolerance Were Assessed at Baseline and at 26th Weeks.
Vitamin D3 supplementation doen not change lung functions and exercise tolerance in vitamin D3 deficient ACO patient was the null hypothesis of the research.
- Trial name
- NCT03880734
- Testing
- Cholecalciferol
- Where
- Bangladesh
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
COPD
The Effects of Creative Dance Based Exercise Training on Respiratory, Balance and Cognitive Functions, Respiratory and Peripheral Muscle Strength and Functional Capacity in Patients With Chronic Obstructive Pulmonary Disease (COPD)
COPD is a common, preventable and treatable disease associated with an increased chronic inflammatory response of the airways and lungs to harmful gases and particles and characterized by progressive airflow restriction, which is…
- Trial name
- NCT04039334
- Testing
- Conventional Chest Physiotherapy, Creative Dance Based Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Bezmialem Vakif University
Asthma
Effects of Particle Size in Small Airways Dysfunction
The airways in the lungs get smaller the further into the lungs they go. Most simple measurements of lung function only reflect the larger 'central' airways and do not provide information on the smaller 'peripheral' airways.
- Trial name
- MAN03 (NCT01892787)
- Testing
- Formoterol, Salmeterol
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of Dundee
Chronic Obstructive Pulmonary Disease
Withdrawal of Inhaled Corticosteroids in Patients With COPD in Primary Care
Guidelines recommend inhaled corticosteroids (ICS) for patients with moderate to severe chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT00440687
- Where
- United Kingdom
- Volunteers
- 256 people
- Sponsor
- Queen Mary University of London
COPD
Inspiration Point-A Digital Pulmonary Rehabilitation Tool Management Interventions
The purpose of this study is to measure the feasibility of use of a digital pulmonary rehabilitation tool compared with standard care home program pulmonary rehabilitation.
- Trial name
- NCT03801330
- Testing
- Usual Care Pulmonary Rehabilitation Program, Pulmonary Rehabilitation Software-Based Home Program
- Where
- 4 sites in United States
- Volunteers
- 48 people
- Sponsor
- Blue Marble Rehab Inc
Chronic Obstructive Pulmonary Disease
The Microcirculatory Characteristics of the Heart and Lung Meridians: A Study of COPD Patients and Healthy Adults
Although some important progresses were made in the field of the meridian research, no breakthroughs have been achieved. Besides,there are some problems in meridian researches.
- Trial name
- NCT04242030
- Testing
- Moxibustion, Laser doppler flowmetry
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Zhejiang Chinese Medical University
Pleural Effusions, Chronic, Pleural Effusion, Malignant
Respiratory Function of Dexmedetomidine in Patients Undergoing Pleuroscopy
The primary objective of this prospective trial will be to assess the effects of dexmedetomidine administration on oxygenation and respiratory function in patients undergoing diagnostic or therapeutic medical…
- Conditions
- Pleural Effusions, Chronic, Pleural Effusion, Malignant, Pleural Diseases
- Trial name
- NCT03597828
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Attikon Hospital
Pulmonary Disease, Chronic Obstructive
Chronic Obstructive Pulmonary Disease (COPD) Post-hospitalization Study
This trial is a randomized, double-blind, parallel-group, multicenter study to be conducted in the United States. The purpose of the study is to evaluate the rate of exacerbations of chronic obstructive pulmonary disease (COPD)…
- Trial name
- NCT01110200
- Testing
- ADVAIR DISKUS 250/50 mg BID, SEREVENT 50 mcg BID
- Where
- 103 sites in United States, Argentina and 1 more
- Volunteers
- 639 people
- Sponsor
- GlaxoSmithKline
Graft Vs Host Disease
Ibrutinib and Rituxan for Chronic GVHD
This is a phase II trial evaluating the safety and efficacy of the combination of Ibrutinib and Rituximab as primary treatment of chronic GVHD. We plan to enroll 35 patients on this study.
- Trial name
- NCT04235036
- Testing
- Rituximab, Ibrutinib
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Northside Hospital, Inc.
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