Clinical trials: Obstructive Chronic Pulmonary Disease
Chronic Obstructive Pulmonary Disease
Study to Evaluate the Effect of Megestrol Acetate in Severe Chronic Obstructive Pulmonary Disease With Loss of Weight
The purpose of this trial is to study the effect of megestrol acetate in the gain of body weight in patients with severe Chronic obstructive pulmonary disease in order to improve the survival of the patients.
- Trial name
- NCT00507949
- Testing
- Megestrol acetate
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Rottapharm Spain
Myeloid Leukemia, Chronic
Evaluation of the Persistence of the Complete Molecular Remission After Stopping Imatinib Chronic Myeloid Leukemia
The first purpose of this study is to evaluate the persistence of the complete molecular remission in patients with Chronic Myeloid Leukemia after stopping imatinib treatment (determine by Reverse Transcription real-time…
- Trial name
- STIM (NCT00478985)
- Testing
- Imatinib ending
- Where
- 24 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Bordeaux
COPD (Chronic Obstructive Pulmonary Disease), Asthma Copd
Self-Management in Adults With Asthma or COPD
This study is a single-blind (evaluator-blind), parallel-group randomized controlled trial comparing two approaches to home-based pulmonary rehabilitation self-management training in individuals with chronic respiratory disease…
- Trial name
- NCT07742085
- Testing
- Video Animation, brochure education
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Mustafa Kemal University
Migraine Disorders
Occipital Nerve Stimulation (ONS) for Migraine: OPTIMISE
The primary objective of this study is to evaluate the safety and efficacy of occipital nerve stimulation (ONS) using the Boston Scientific Corporation (BSC) Precision™ System in the management of intractable chronic migraine…
- Trial name
- OPTIMISE (NCT01775735)
- Testing
- Occipital nerve stimulator
- Where
- 10 sites in United States
- Volunteers
- 28 people
- Sponsor
- Boston Scientific Corporation
Pulmonary Disease, Chronic Obstructive
To Evaluate Effects of GSK2256294 on Pulmonary Artery Pressure in Healthy Volunteers Under Normoxic and Hypoxic Conditions
The study evaluates the effect of GSK2256294 exposure at steady state on pulmonary artery systolic pressure (PASP) in healthy volunteers, under hypoxic conditions, after 7 days of dosing.
- Trial name
- NCT02262689
- Testing
- GSK2256294
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease (COPD)
Use of the SMART COPD Physical Activity App in Pulmonary Rehabilitation
The investigators are carrying out a feasibility study to explore whether an app for physical activity in Chronic Obstructive Pulmonary Disease (COPD) is acceptable to people with the condition and to healthcare professionals who…
- Trial name
- NCT02691104
- Testing
- SMART COPD app to promote physical activity in COPD. Used in conjunction with a Fitbit Charge, Control
- Where
- 3 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Chronic Obstructive Pulmonary Disease, Dyspnea
Efficacy and Mechanism of NIV in Relieving Dyspnea After Exercise in Patients With Stable Severe COPD
Exertional dyspnea is a major cause of exercise limitation and anxiety, and contributes importantly to reduced quality of life for patients with COPD.
- Trial name
- NCT03568747
- Testing
- noninvasive ventilation, oxygen therapy
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Acute Lung Injury, Chronic Obstructive Pulmonary Disease (COPD)
Imaging of Peri-operative (periOP) Lung Injury
The aim of study is to determine if 99mTc Annexin V-128 (AxV- 128/Tc) single photon emission computed tomography (SPECT)-computed tomography (CT) can detect perioperative lung injury.
- Trial name
- NCT02978885
- Testing
- SPECT-CT imaging, AxV-128/Tc, Whipple procedure
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Columbia University
Tracheomalacia, Tracheobronchomalacia
Tracheal Mechanics During Bronchoscopy
The main purpose of this study is use a new type of measurement to help decide what kind of therapy would help people with a collapsing windpipe or tracheomalacia.
- Trial name
- NCT00536315
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Pulmonary Disease, Chronic Obstructive
Efficacy of Acupuncture in Exercise Tolerance in Patients With COPD
Chronic Obstructive Pulmonary Disease (COPD) is nowadays the 4th cause of death in the world and it´s expected to become the 3rd cause of death in 2020 and the majority cause of morbidity.
- Trial name
- NCT03767140
- Testing
- acupuncture
- Where
- Portugal
- Volunteers
- 29 people
- Sponsor
- Instituto de Ciências Biomédicas Abel Salazar
Chronic Obstructive Pulmonary Disease (COPD)
A Study of in Elderly Patients With COPD on Long-term Home Oxygen Therapy Combined With MCI
The goal of this clinical trial is to learn The effects of a health education programme based on BCW theory on elderly patients with chronic obstructive pulmonary disease and mild cognitive impairment The main questions it aims…
- Trial name
- COPD、MCI (NCT06852716)
- Testing
- Health education based on BCW theory, Routine health education
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Yuanjiao Yan
Pulmonary Disease, Chronic Obstructive
A Study to Test the Combination of Tiotropium and Olodaterol Using the Respimat® Inhaler in People With Chronic Obstructive Pulmonary Disease (COPD) Who Have Different Abilities to Inhale
To demonstrate the efficacy of inhaled tiotropium + olodaterol via Respimat® on lung function in patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD) with optimal and sub-optimal Peak Inspiratory Flow…
- Trial name
- NCT04223843
- Testing
- Tiotropium + olodaterol
- Where
- 26 sites in United States, Germany
- Volunteers
- 213 people
- Sponsor
- Boehringer Ingelheim
Asthma, Chronic Obstructive Pulmonary Disease
Study of the Metabolism of Two Magnesium Supplements in Healthy Volunteers
The present study is part of a project titled 'Magnesium in asthma and chronic obstructive pulmonary disease'. The hypothesis of the main project is that daily magnesium supplement will benefit patients with asthma and chronic…
- Trial name
- NCT01113138
- Testing
- Mablet (Magnesium-supplement), Magnesium Sulfate
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Chronic Pain, Back Pain Lower Back Chronic
Mind-body Treatments for Chronic Back Pain
Participants with chronic back pain will complete an online prescreen. They will then be randomized to one of two different studies: a placebo vs. waitlist study or a psychotherapy vs.
- Conditions
- Chronic Pain, Back Pain Lower Back Chronic, Back Pain, Low
- Trial name
- NCT03294148
- Testing
- Psychotherapy Treatment for Chronic Back Pain
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Copd
Short Acting Agents Vs Long Acting in Frequent Excerbator COPD Patients
Chronic obstructive pulmonary disease is heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea, cough, sputum production, exacerbations) due to abnormalities of the airways (bronchitis…
- Trial name
- NCT05748977
- Testing
- SABA SAMA ICS Vs LABA LAMA ICs
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
COPD Exacerbation Acute
The Effect of Airway and Chest Wall Oscillation on Respiratory Functions in COPD Patients in Acute Exacerbation
Chronic obstructive pulmonary disease (COPD); It is a common, treatable and preventable disease characterized by progressive and irreversible airflow limitation and has systemic effects with respiratory system involvement.
- Trial name
- NCT06274957
- Testing
- CONTROL, PEP DEVICE, HFCWO DEVICE
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Saglik Bilimleri Universitesi
Asthma Chronic
Thoracic Spine Rotation Stretching and Scapular Retraction in Asthma Patients
Patients with asthma frequently experience upper back stiffness and rounded shoulders and tightness in the thoracic region. Rib cage stiffness occurs due to poor posture and muscle tightness, which leads to decreased chest…
- Trial name
- NCT07508267
- Testing
- Thoracic Spine Rotation Stretching, Scapular retraction
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
COPD
Daily Magnesium-treatment of Patients With Chronic Obstructive Pulmonary Disease
The present study is part of a project titled 'Magnesium in asthma and chronic obstructive pulmonary disease'. The hypothesis of the main project is that a daily magnesium supplement will benefit patients with asthma and chronic…
- Trial name
- NCT01118936
- Testing
- Magnesium supplement (magnesium hydroxide/ -oxide)
- Where
- Denmark
- Volunteers
- 11 people
- Sponsor
- University of Aarhus
Chronic Obstructive Pulmonary Disease (COPD)
Fractional Exhaled Nitric Oxide and Exacerbations of COPD
Chronic obstructive pulmonary disease (COPD) is a heterogeneous condition with recurrent exacerbations despite guideline-based therapy.
- Trial name
- NCT07396311
- Testing
- No intervention assigned
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital
Pulmonary Disease, Chronic Obstructive
Safety and Efficacy of Two Different Doses of Ipratropium Bromide Versus ATROVENT® Inhalation Aerosol in Adults With Chronic Obstructive Pulmonary Disease
The objective of this study is to confirm that chronic dosing of 20 mcg and 40 mcg of ipratropium bromide, administered via the RESPIMAT device, demonstrates clinical comparability and similar safety profiles to the 36 mcg dose…
- Trial name
- NCT02177344
- Testing
- Low dose of Ipratropium bromide, High dose of Ipratropium bromide, Atrovent
- Volunteers
- 646 people
- Sponsor
- Boehringer Ingelheim
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