Clinical trials: Obstructive Ventilation Disorder
Atrial Fibrillation, Sleep Apnea
CPAP in AF Patients With OSA
Obstructive sleep apnea is associated with atrial fibrillation. This study is to evaluate the effect of continuous positive airway pressure on the burden of atrial fibrillation in the patients with obstructive sleep apnea and…
- Trial name
- CPAPAF (NCT04513483)
- Testing
- continuous positive airway pressure
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- National Taiwan University Hospital
Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea Syndrome
Portable Monitoring Device for the Diagnosis of Sleep Apnea in Patients With Chronic Obstructive Pulmonary Disease
Introduction: The prevalence of overlap between Chronic Obstructive Pulmonary Disease (COPD) and Obstructive Sleep Apnea Syndrome (OSAS) is around 10%.
- Trial name
- NCT01026207
- Testing
- Polysomnography
- Where
- 2 sites in Brazil
- Volunteers
- 72 people
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Obstructive Sleep Apnea
Whole Body Vibration for OSA
Obstructive Sleep Apnea (OSA) is a serious medical condition which is increasing in the United States and significantly increases risks for other diseases, morbidity and mortality.
- Trial name
- NCT03377621
- Testing
- Whole Body Vibration
- Where
- United States
- Sponsor
- University of California, Los Angeles
OSA - Obstructive Sleep Apnea
Comparative Study of CPAP Predictive Equations and In-laboratory Manual Titration in Thai Patients With Obstructive Sleep Apnea
The goal of this observational study is to compare predictive equations for continuous positive airway pressure (CPAP) with in-laboratory manual titration in patients with obstructive sleep apnea (OSA).
- Trial name
- NCT07376343
- Testing
- Sleep test, Predictive equations of continuous positive airway pressure (CPAP)
- Where
- 2 sites in Thailand
- Volunteers
- 150 people
- Sponsor
- Thammasat University
Obstructive Sleep Apnea
Validation of a Ring-type Wearable Device
Study name: Validation of a Ring-type Wearable Device for Blood Oxygen Monitoring and Obstructive Sleep Apnea Syndrome Screening in Adult Chinese.
- Trial name
- NCT05746338
- Testing
- Ring-type wearable device, Overnight polysomnography
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Obstructive Sleep Apnea, Stroke
Sleep Apnea Treatment After Stroke (SATS)
The purpose of this study is to determine if treating stroke patients who have obstructive sleep apnea with continuous positive airway pressure will improve symptoms caused by the stroke.
- Trial name
- NCT00282815
- Testing
- continuous positive airway pressure or CPAP
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Michigan
Asthma in Children
Sensitivity of Forced Oscillation Technique in Children With Asthma and Normal Spirometry
Exhibiting variable airway obstruction is a key factor in the diagnosis of asthma but too often it is undetected by spirometry. Study hypothesis: The forced oscillation technique (FOT) will show airway obstruction in asthmatic…
- Trial name
- NCT03755908
- Testing
- Forced oscillation technique (FOT)
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Rambam Health Care Campus
Chronic Obstructive Pulmonary Disease
Combined Effects of Global Posture Re-education and Active Cycle of Breathing Technique in COPD
The randomized controlled trial will involve 30 participants, with Group A receiving GPRM and ACBT, while Group B follows the conventional COPD model that includes ACBT only.Assessments of heart rate, physical fitness, and…
- Trial name
- NCT06308289
- Testing
- Global Posture Re-education, Active Cycle of Breathing Technique
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Riphah International University
Asthma, Allergic Rhinitis
Effects of Lipoic Acid on Oxidative, Inflammatory and Functional Markers in Asthmatic Patients
The aim of the study is to use the antioxidant and antiinflammatory effects of lipoic acid to improve the quality of life of patients with asthma.
- Trial name
- NCT01221350
- Testing
- Lipoic acid
- Where
- 2 sites in Mexico
- Volunteers
- 55 people
- Sponsor
- Centro Universitario de Ciencias de la Salud, Mexico
Obstructive Sleep Apnea
Effect of Zopiclone on Compliance With Continuous Positive Airway Pressure in Obstructive Sleep Apnea
The clinical population targeted will be newly diagnosed patients with polysomnographically diagnosed OSA who are not currently taking hypnotics for concomitantly diagnosed insomnia.
- Trial name
- NCT01369576
- Testing
- Zopiclone
- Where
- 4 sites in Canada
- Volunteers
- 264 people
- Sponsor
- OSR Medical Inc.
Sleep Apnea, Obstructive, Pre-Eclampsia
Screening and Treatment of Obstructive Sleep Apnea in High-risk Pregnancy
This is an open-label multicenter randomized-controlled trial in 3 tertiary care hospitals including Ramathibodi Hospital, Phramongkutklao Hospital and Rajavithi Hospital.
- Conditions
- Sleep Apnea, Obstructive, Pre-Eclampsia, Hypertension, Pregnancy-Induced
- Trial name
- NCT03356106
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- 3 sites in Thailand
- Volunteers
- 340 people
- Sponsor
- Ramathibodi Hospital
Obstructive Sleep Apnea (OSA), Mandibular Advancement Device
Clinial Study of Treatment With Mandibular Advancement Device in Patients With Obstructive Sleep Apnea Across 6 General Hospitals
Study Objectives: To retrospectively study mandibular advancement treatment efficacy using apnea-hypopnea index (AHI) and oxygen desaturation index (ODI), in a large cohort of patients, in 'real world' settings across 6 general…
- Trial name
- RACEMADT (NCT06837285)
- Testing
- mandibular advancement device
- Where
- 6 sites in Belgium
- Volunteers
- 182 people
- Sponsor
- University Hospital, Antwerp
Acute Respiratory Distress Syndrome (ARDS), Pneumonia
Medical Device Clinical Trial Without CE Marking to Evidence Safety and Performance of the INBENTUS VERSATILE Ventilator in Patients Requiring Assisted/Controlled Mechanical Ventilation and Weaning.
Pre-market clinical trial on 81 aldults participants to evidence safety and performance of the non-CE-marked medical device INBENTUS VERSATILE ventilator.
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Pneumonia, COPD (Chronic Obstructive Pulmonary Disease), Postoperative Respiratory Distress
- Trial name
- NCT07432191
- Testing
- INBENTUS VERSATILE
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Iconic Solutions By Murcia SL
Obstructive Sleep Apnea
Mechanism of Endothelial Dysfunction in Obstructive Sleep Apnea (OSA)
The investigators hypothesized that patients with Obstructive Sleep Apnea (OSA) who are free of any cardiovascular disease will have early microcirculatory changes that are unique to OSA, and therefore would resolve with…
- Trial name
- NCT01027078
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Emphysema
Ventilation-Perfusion Discrepancy Index Versus Conventional Anatomic-Physiologic Assessment for Target Lung Lobe Selection in Endobronchial Valve Placement: A Multicenter, Randomised Controlled Trial
The goal of this clinical trial is to learn if a Ventilation-Perfusion Discrepancy Index (VQDI)-guided strategy for selecting the target lung lobe can improve outcomes compared to the standard strategy in patients with severe…
- Trial name
- NCT07403617
- Testing
- VQDI-assisted target lung lobe selection strategy, Conventional target lung lobe selection strategy
- Where
- China
- Volunteers
- 285 people
- Sponsor
- China-Japan Friendship Hospital
Hypotonia, Muscle, Obstructive Sleep Apnea
Long-term Evaluation of Nasopharyngeal Airway in Hypotonia
This research is studying the long term use of a nasal airway device (self-supporting nasopharyngeal airway; "ssNPA") in children with hypotonic upper airway obstruction to learn about its effectiveness and tolerability as a…
- Conditions
- Hypotonia, Muscle, Obstructive Sleep Apnea, Nasal Airway Obstruction
- Trial name
- NCT06614582
- Testing
- Self-Supporting Nasopharyngeal Airway (ssNPA)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Non-alcoholic Fatty Liver Disease, Sleep Apnea, Obstructive
Obstructive Sleep Apnea and Non-alcoholic Fatty Liver Disease
Obstructive sleep apnea (OSA) and nonalcoholic fatty liver disease (NAFLD) are frequently encountered in patients with metabolic syndrome (MS). Several data suggest that OSA per se could be a risk factor of liver injury.
- Trial name
- NASHSAS (NCT03373643)
- Testing
- OSA screening
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
COPD
Efficacy of AZD3199 in Chronic Obstructive Pulmonary Disease (COPD) Patients
The purpose of this study is to investigate the efficacy, safety and tolerability of 4 weeks treatment with AZD3199 in moderate to severe COPD.
- Trial name
- GLAD (NCT00929708)
- Testing
- AZD3199, formoterol
- Where
- 38 sites in Bulgaria, Canada and 3 more
- Volunteers
- 329 people
- Sponsor
- AstraZeneca
Obstructive Sleep Apnea
The Effects of Oral Appliance Therapy on Masseter Muscle Activity in Obstructive Sleep Apnea
Previous studies have shown that contractions of the jaw-closing masseter muscle (MAS) often occur shortly after respiratory events during sleep in obstructive sleep apnea (OSA) patients.
- Trial name
- NCT02011425
- Testing
- mandibular advancement appliance
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- Université de Montréal
Respiratory Disease, Asthma
A System to Classify Treatable Traits in Primary Care
This study proposes an approach to address an urgent unmet need in clinical practice, namely a pragmatic method of establishing what is the cause of a patient's complaint and the next steps to address this problem.
- Conditions
- Respiratory Disease, Asthma, Copd
- Trial name
- SMART (NCT05357274)
- Testing
- Diagnostic testing
- Where
- Ireland
- Volunteers
- 200 people
- Sponsor
- Royal College of Surgeons, Ireland
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