Clinical trials: Obstructive Ventilation Disorder
Chronic Obstructive Pulmonary Disease
Identification and Dynamics With Cerebral Functional Magnetic Resonance Imaging
Chronic obstructive pulmonary disease (COPD) is a chronicle inflammatory disease with a non reversible diminution of the airway flow.
- Trial name
- CHAOSBOLD (NCT01331070)
- Testing
- cerebral fMRI
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post Acute Sequelae of SARS CoV 2 Infection, Obstructive Sleep Apnea
Predictors of Post-COVID-19 Clinical and Cognitive Consequences
The CDC describes Post-acute sequelae of SARS-COV-2 infection (PASC) for the wide range of physical and mental health consequences experienced by some patients.
- Trial name
- SCLC (NCT06291870)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Sleep Apnea, Insomnia
Randomized Controlled Trial of a Self-help Book for Insomnia in Patients With Co-morbid OSA and Insomnia
Obstructive sleep apnea (OSA) is a common sleep disorder treated with continuous positive airway pressure (CPAP). Some OSA patients also suffer from co-morbid insomnia.
- Trial name
- NCT02279056
- Testing
- Self-help book for insomnia, Sleep hygiene advice
- Where
- Norway
- Volunteers
- 181 people
- Sponsor
- University of Bergen
Obstructive Sleep Apnea
Personal Therapy Comfort Settings Pilot Clinical Study
350 participants will be enrolled in this study. The target population are patients newly diagnosed with OSA and starting CPAP treatment.
- Trial name
- NCT05376137
- Testing
- continuous positive airway pressure (CPAP)
- Where
- Australia
- Volunteers
- 66 people
- Sponsor
- ResMed
Sleep Apnea, Sleep Apnea, Obstructive
Predictive Accuracy of MATRx Plus in Identifying Favorable Candidates for Oral Appliance Therapy
Obstructive sleep apnea (OSA) is a common disease that is largely un-diagnosed and untreated. Standard treatment for obstructive sleep apnea, nasal continuous positive airway pressure (CPAP), entails use of a nose mask to deliver…
- Conditions
- Sleep Apnea, Sleep Apnea, Obstructive, Sleep Disordered Breathing
- Trial name
- NCT03217383
- Testing
- MATRx plus
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- Zephyr Sleep Technologies
Obstructive Sleep Apnea
Performance of the Tasman Continuous Positive Airway Pressure (CPAP) System
Assessment of the performance of the Tasman CPAP system in treating obstructive sleep apnea. The purpose of this study is to (1) evaluate the performance of this system in the efficacy of the treatment in comparison to S8 Escape…
- Trial name
- NCT01171066
- Testing
- Tasman CPAP system
- Where
- Australia
- Volunteers
- 57 people
- Sponsor
- ResMed
OSA - Obstructive Sleep Apnea
BioMAD - A Non-inferiority Study
Evaluation of the effectiveness of a new mandibular advancement device (BioMAD) in the treatment of obstructive sleep apnea.
- Trial name
- BioMAD (NCT07845331)
- Testing
- BioMAD
- Volunteers
- 20 people
- Sponsor
- University of Lausanne Hospitals
Obstructive Sleep Apnea, Heart Failure
Mandibular Advancement Device for Treatment of Obstructive Sleep Apnea and Its Impact on Cardiac Remodeling
Primary aim: The MOSAIC trial aims to assess the impact of a mandibular advancement device (MAD) on Apnea-Hypopnea Index (AHI) in Asian patients with Heart Failure with reduced Ejection Fraction (HFrEF) and obstructive sleep…
- Trial name
- MOSAIC (NCT02948894)
- Testing
- Mandibular advancement device
- Where
- 2 sites in Singapore
- Volunteers
- 100 people
- Sponsor
- National University of Singapore
Sleep Apnea
Prevention Of Delirium in Elderly With Obstructive Sleep Apnea (PODESA)
Delirium is a common complication in elderly patients following surgery. Patients who develop delirium after surgery are at increased risk for serious complications, and even death.This multi-centre randomized controlled trial…
- Trial name
- PODESA (NCT02954224)
- Testing
- CPAP treatment
- Where
- 3 sites in Canada
- Volunteers
- 220 people
- Sponsor
- University Health Network, Toronto
Obstructive Sleep Apnea
The Effect of CPAP Treatment on Cognitive Functions, Anxiety, and Affective Symptoms
Long term, prospective study of continuous positive airway pressure treatment influence on cognitive functions in patients with obstructive sleep apnea syndrome.
- Trial name
- NCT03866161
- Testing
- Continuous positive airway pressure
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Olomouc
Fibromyalgia Syndrome, Obstructive Sleep Apnea Syndrome
Fibromyalgia Syndrome on Anthropometric and Ultrasonographic Measurements in Obstructive Sleep Apnea Syndrome
Obstructive type sleep apnea syndrome is a clinical condition characterized by apnea, hypopnea and oxygen desaturation due to narrowing of the upper airway during sleep. Obesity is considered a major predisposing factor for OSAS.
- Trial name
- NCT06536894
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Chronic Lung Diseases, COPD
Written Disclosure Therapy for Anxiety and Stress in Patients With Chronic Lung Disease
The purpose of this study is to determine whether Written Disclosure Therapy (WDT) is of any benefit to patients with chronic lung diseases who are participating in pulmonary rehabilitation.
- Conditions
- Chronic Lung Diseases, COPD, Pulmonary Fibrosis
- Trial name
- NCT00911794
- Testing
- Disclosure Writing (Written Disclosure Therapy)
- Volunteers
- 66 people
- Sponsor
- Winthrop University Hospital
Chronic Obstructive Pulmonary Disease (COPD), Asthma (Diagnosis)
Breathlessness Perceptions Within Respiratory Diseases
Breathlessness is a complex symptom that results in poor quality of life, increased hospitalisations and increased mortality. Breathlessness is influenced by physiological, psychological and functional factors but these are…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Asthma (Diagnosis), Interstitial Lung Disease (ILD), Bronchiectasis
- Trial name
- BiRD (NCT07648082)
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Obstructive Sleep Apnea
Titration of Continuous Positive Airway Pressure Could Predict Success of Oral Appliance to Treat Sleep Apnea
Background: The oral appliances have been increasingly used in the treatment of primary snoring and in patients with mild obstructive sleep apnea syndrome besides being treatment options in adults with moderate to severe sleep…
- Trial name
- NCT01336556
- Testing
- Oral appliance
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Associacao Fundo de Incentivo a Psicofarmcologia
Mild-Moderate Obstructive Sleep Disordered Breathing
Non-Inferiority Trial of Acute HFT Versus nCPAP
Order randomized crossover non-inferiority study evaluating the acute efficacy of High Flow Therapy (HFT) as compared to nasal Continuous Positive Airway Pressure therapy (CPAP) in the management of apnea / hypopnea index (AHI).
- Trial name
- NCT01860560
- Testing
- High-Flow Therapy, Continuous Positive Airway Pressure
- Where
- United States
- Sponsor
- Vapotherm, Inc.
Obstructive Sleep Apnea Syndrome
Cytokine Profiles in Children With Obstructive Sleep Apnea
The purpose of this study is to compare the cytokine profile of tonsillar and peripheral blood mononuclear cells in patients with obstructive sleep apnea (OSA) and to compare the blood mononuclear cell cytokine secretion profile…
- Trial name
- NCT00456573
- Testing
- tonsillectomy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Obstructive Sleep Apnea of Adult
Efficacy of Oropharyngeal Exercises for Patients With Obstructive Sleep Apnea Using Mandibular Advancement Device
Combined treatment with MAD and OE for adult patients with obstructive sleep apnea can significantly (i) improve muscle strength and endurance; (ii) reduce the severity of sleep apnea.
- Trial name
- NCT05717959
- Testing
- Oropharyngeal Exercises
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Cheng-Kung University Hospital
Pulmonary Emphysema
Video Assisted Thoracic Surgery (VATS) Fissure Completion Prior to Zephyr® Endobronchial Valve Insertion
Prospective, multi-centre, pilot study aimed to evaluate the effect of Video Assisted Thoracic Surgery (VATS) fissure completion on the efficacy of endobronchial valve insertion (Zephyr Valve) in the treatment of subjects with…
- Trial name
- COVE (NCT04465461)
- Testing
- Video-assisted thoracoscopic surgery (VATS) fissure completion, Zephyr Valve insertion
- Where
- 2 sites in Australia
- Volunteers
- 9 people
- Sponsor
- Pulmonx Corporation
Obstructive Sleep Apnea Syndrome
The Effect of Intubation Without Muscle Relaxation on Post Operative Recovery Conditions: Double Blind Randomized Controlled Study
The primary aim of this study is to research the effect of intubation without muscle relaxant on post-operative recovery conditions in patients with OSAS (obstructive sleep apnea syndrome).
- Trial name
- NCT03824470
- Volunteers
- 90 people
- Sponsor
- Yuzuncu Yil University
Obstructive Sleep Apnea Syndrome
Telemedicine to Enhance Adherence to CPAP Therapy in Patients With OSAS
We hypothesize that the use of telemedicine combined with support interventions by short messages, telephone calls and ambulatory visits to control CPAP treatment during the first month improves adherence and reduces unresolved…
- Trial name
- NCT01715194
- Testing
- Telemedicine intervention
- Where
- Switzerland
- Volunteers
- 240 people
- Sponsor
- Otto D. Schoch
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