Clinical trials: Obturation
Dental Occlusion, Primary Teeth
Digital Occlusal Analysis and Bite Force Evaluation of Primary Molars Restored With Zirconia Crowns Using T-Scan
The goal of this observational study is to evaluate the adaptation of occlusion and bite force after zirconia crown restoration in children with pulp-treated primary molars.
- Conditions
- Dental Occlusion, Primary Teeth, Pulp-treated Primary Molars, Zirconia Crowns
- Trial name
- NCT07276841
- Testing
- Pulp Therapy and Zirconia Crown Restoration of Primary Molars with T-Scan Occlusal Analysis
- Where
- Egypt
- Volunteers
- 11 people
- Sponsor
- Cairo University
Dental Occlusion
Patient Perception and Oral Function of Implant Restorations
The overall aim is to evaluate the patient-reported outcome and efficiency of replacing posterior teeth with implant-supported crowns compared to RDPs and no treatment.
- Trial name
- REPLACE (NCT06463405)
- Testing
- Splinted
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Complications
Standard Length Catheters vs Long Catheters in Peripheral Vein Cannulation.
The Long and Short is a prospective, randomized, controlled, open label trial to test the complications of different device for peripheral vein cannulation, standard length (about 5 cm in length) and long catheter (about 12 cm in…
- Trial name
- Long&short (NCT01917253)
- Testing
- Standard Device for peripheral vein cannulation, Long Catheters for peripheral vein cannulation
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- ASL TO2 Torino
Ischemic Heart Disease
In-hospital and Long-term Outcomes for Percutaneous Chronic Total Coronary Occlusion Revascularization in a High-volume, Multi-operator Program
The purpose of this study is to study whether percutaneous chronic total occlusion (CTO) revascularization, by the use of Percutaneous Coronary Intervention (PCI), stenting, guidewire, and catheter, improves a patient's quality…
- Trial name
- Perspective (NCT01946724)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Piedmont Healthcare
Coronary Artery Ischemia
Remote Myocardial Ischemic Preconditioning in Humans
Ischemic preconditioning (IP) has been shown in animal studies to increase the myocardial tolerance to subsequent ischemia. Our primary hypothesis is that remote IP reduces myocardial ischemic injury during PCI.
- Trial name
- RemoteMIPH (NCT00588042)
- Testing
- Blood pressure cuff
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Mayo Clinic
Adverse Reaction to Drugs Affecting the Gastrointestinal System
ELIGIBLE (Efficacy of Left atrIal Appendage Closure After GastroIntestinal BLEeding)
Patients with atrial fibrillation requiring anticoagulation treatment are at high risk of gastrointestinal bleeding. The investigators propose the percutaneous stop the oral anticoagulation and closure of the left atrial…
- Trial name
- ELIGIBLE (NCT01628068)
- Testing
- Left atrial appendage occlusion
- Where
- 6 sites in Spain
- Volunteers
- 120 people
- Sponsor
- Hospital Clinic of Barcelona
Congenital Diaphragmatic Hernias
Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) for CDH
The rationale for fetal therapy in severe congenital diaphragmatic hernia (CDH) is to restore adequate lung growth for neonatal survival.
- Trial name
- FETO (NCT02530073)
- Testing
- Fetoscopic Endoluminal Tracheal Occlusion (FETO)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Connecticut Children's Medical Center
Ischemic Cerebrovascular Accident
Interest of Direct Aspiration First Pass Technique (ADAPT) for Thrombectomy Revascularisation of Large Vessel Occlusion in Acute Ischaemic Stroke
Mechanical thrombectomy (TM) is now validated through 4 randomized controlled trials of high scientific level as the reference treatment of cerebral infarction associated with proximal cerebral occlusion (MR CLEAN, ESCAPE 2014…
- Trial name
- ASTER (NCT02523261)
- Testing
- direct aspiration procedure, stent retriever procedure
- Where
- 8 sites in France
- Volunteers
- 381 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Pupillary Occlusion
Influence of Gaze Shift and Emotions on Symptoms of Blepharospasm
Blepharospasm (BEB) is a focal dystonia characterized by forceful, involuntary contractions of the orbicularis oculi muscle. (Jankovic et al 1983) Patients with BEB report task and situation specific modulations of their…
- Trial name
- NCT01759745
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kirsten Elwischger, MD
Atrial Fibrillation, Stroke
WATCHMAN Left Atrial Appendage System for Embolic PROTECTion in Patients With Atrial Fibrillation
This is a multi-center, prospective, randomized study, stratified by center, comparing the WATCHMAN device to long term warfarin therapy, demonstrating that the treatment arm is non-inferior to the control arm.
- Trial name
- NCT00129545
- Testing
- WATCHMAN Left Atrial Appendage Closure Technology, Warfarin
- Where
- 62 sites in United States, Czechia and 1 more
- Volunteers
- 800 people
- Sponsor
- Boston Scientific Corporation
Occlusion
Characterization of the Temporo-masseteric Nerve Block (TMNB) in Healthy Subjects
The proposed pilot study is aimed at preliminary characterization of the TMNB injection in 20 healthy volunteers. Assessment of bite-force distribution and surface electromyographic activity of the temporalis and the masseter…
- Trial name
- NCT05507164
- Testing
- Temporomasseteric Nerve Block
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Overjet, Dental
Sleep, Upper Airway and Dental Occlusion in Children With Large Overjet
This project examines sleep (e.g. prevalence of obstructive sleep apnea(OSA)), dimension of upper airway, jaw function, well-being and quality of life in children with large overjet compared to a control group.
- Trial name
- NCT04964830
- Testing
- Orthodontic treatment with functional appliance (MAD)
- Where
- Denmark
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Atrial Fibrillation, Aortic Stenosis
Comparison of Left Atrial Appendage Occlusion vs Standard Medical Therapy in Patients in AF Undergoing TAVI
Study category and Rationale Clinical study, Category A. Clinical Phase: Post market study Background and Rationale: Left atrial appendage occlusion (LAAO) allows avoiding oral anticoagulation and provides at the same time an at…
- Trial name
- TAVI/LAAO (NCT03088098)
- Testing
- LAAO
- Where
- Switzerland
- Volunteers
- 81 people
- Sponsor
- University of Zurich
Chronic Total Occlusion, Occlusion
Impact of CTO PCI (Chronic Total Occlusion Percutaneous Intervention) on Regular Physical Activity
Heart disease is a leading cause of death in the US. . Heart blood vessel chronic total occlusions are 100% blockages of the heart vessels. These patients often suffer from chest pain, shortness of breath, and depression.
- Trial name
- NCT05440084
- Testing
- Chronic total occlusion percutaneous coronary intervention
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Minneapolis Heart Institute Foundation
Retinopathy, Retinal Vein Occlusion
Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodium
The objective of this study is to evaluate the safety and image quality of the investigational dye, MB-102, compared to the control dye (fluorescein sodium) in healthy and diseased eyes using fluorescent angiography for retinal…
- Conditions
- Retinopathy, Retinal Vein Occlusion, Diabetic Retinopathy, Macular Degeneration
- Trial name
- NCT04008121
- Testing
- Fluorescein sodium and Zeiss FF450 fundus camera, MB-102 and Zeiss FF450 fundus camera, Fluorescein sodium and commercially available optical angiography imaging system
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- MediBeacon
Macular Edema
Study Assessing AR-1105 in Subjects With Macular Edema Due to Retinal Vein Occlusion (RVO)
This study will evaluate the safety, tolerability and efficacy of AR-1105 (dexamethasone implant) for the treatment of macular edema (ME) due to retinal vein occlusion (RVO).
- Trial name
- NCT03739593
- Testing
- AR-1105-CF1, AR-1105-CF2
- Where
- 11 sites in United States
- Volunteers
- 49 people
- Sponsor
- Aerie Pharmaceuticals
Liver Cancer, Surgery
Study of Liver Resection With Versus Without Hepatic Inflow Occlusion for the HBV-related HCC
The study aims to compare the perioperative and long-term outcomes of liver resection for HBV-related HCC with versus without hepatic inflow occlusion.
- Trial name
- OHx-NOHx (NCT02563158)
- Testing
- non-occlusion technique
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Chinese PLA General Hospital
Acute Cholangitis
Impact of Positive Bile Cultures on Plastic Biliary Stent Exchange
This prospective, unicenter, randomized controlled trial evaluates whether a positive bile culture at index ERCP with plastic stenting identifies patients who benefit from earlier stent exchange.
- Trial name
- TEMPEST 2 (NCT07379749)
- Testing
- stent exchange, Scheduled biliary stent exchange at one month
- Where
- Romania
- Volunteers
- 140 people
- Sponsor
- Clinical Hospital Colentina
Chronic Total Occlusion of Coronary Artery
Properties of Myocardial Microcirculation in Patients With Different Pathomorphological Substrates, Before and After Recanalization of Coronary Artery CTO
This study will evaluate the changes in myocardial microcirculatory parameters of the collateral donor artery after recanalization of coronary artery chronic total occlusion.
- Trial name
- NCT04060615
- Testing
- percutaneous coronary intervention
- Where
- Serbia
- Volunteers
- 30 people
- Sponsor
- University of Belgrade
Prosthesis Durability
Impact of Mandibular Overdenture Base Construction Techniques on Assessment of Occlusion
This within patient study will be conducted to compare between two different construction techniques (CAD-CAM Milled and Conventional techniques) of 4-implant-assisted complete mandibular overdenture bases regarding the digital…
- Trial name
- NCT06080815
- Testing
- CAD/CAM Complete denture
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University