Clinical trials: Occult GI Bleeding
Healthy Volunteer
Assess Gastrointestinal Blood Loss After Receiving Aspirin or Aspirin Plus Rivaroxaban in Healthy Adult Participants
The primary objective of the study is to determine whether aspirin alone or aspirin combined with various doses of rivaroxaban causes subclinical GI blood loss as determined by the HemoQuant assay.
- Trial name
- NCT05546957
- Testing
- Aspirin, rivaroxaban low dose, rivaroxaban high dose
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Obscure Gastrointestinal Bleeding
Diagnostic Evaluation of Obscure Gastrointestinal Bleeding
Up to 5% of patients with recurrent gastrointestinal (GI) bleeding remain undiagnosed by EGD and colonoscopy, the presumed source of bleeding in these patients being the small intestine.
- Trial name
- NCT00593021
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Occult Gastrointestinal Bleeding, Upper Gastrointestinal Bleeding (UGIB)
PillSense Use in Anemia and Hemoccult
In this study, participants will be offered a PillSense™ capsule, a small capsule to swallow, which can detect the presence of blood in the upper digestive tract within about 10 minutes.
- Trial name
- PillSense™ (NCT06951490)
- Testing
- PillSense™
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- AdventHealth
Gastrointestinal Bleeding, Antiplatelet Agents
How Often Does the Fecal Test for Occult Blood Turn Positive After Using Blood Thinners?
Blood thinner medications used for cardiovascular disease can cause gastrointestinal bleeding. Early detection of invisible bleeding by performing occult fecal blood test (called fecal immunochemical test, or FIT) can uncover…
- Conditions
- Gastrointestinal Bleeding, Antiplatelet Agents, Oral Anticoagulant Therapy
- Trial name
- NCT07327853
- Testing
- Fecal Immunochemical Test (FIT)
- Where
- Jordan
- Volunteers
- 200 people
- Sponsor
- Jordan Collaborating Cardiology Group
Occult GI Bleeding
A Prospective Evaluation of Same Day Bidirectional Endoscopy for Occult Bleeding
This study is a prospective evaluation of patients with occult (hidden) GI bleeding without iron deficiency. Such patients usually undergo a diagnostic colonoscopy as a standard of care.
- Trial name
- NCT00636597
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- US Department of Veterans Affairs
Gastrointestinal Bleeding
Occult Obscure Gastrointestinal Bleeding
To test the activity of a polyglucosamine (PG) together with a Standard Management protocol (SM) on the occult and obscure gastrointestinal bleeding (OGIB) and the clinical symptoms in patients suffering from colonic…
- Trial name
- OGIB (NCT03464539)
- Testing
- PG low molecular weight chitosan
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Blymum Srl
Obscure Gastrointestinal Bleeding
Cap Assisted Balloon Enteroscopy Versus Conventional Balloon Enteroscopy In The Evaluation Of Obscure Gastrointestinal Bleeding: A Randomized Controlled Trial
Gastrointestinal bleeding originating from the small bowel is difficult to diagnose and treat because the small bowel is difficult to see and reach.
- Trial name
- NCT02315404
- Testing
- CAP
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Washington University School of Medicine
Small Bowel Disease, Gastrointestinal Hemorrhage
Bowel Preparation and Prokinetics in Capsule Endoscopy
The aim of this study is to determine whether taking bowel preparation (citramag and senna) or a medicine to speed up transit through the stomach (metoclopramide), will improve the quality of the images seen, increase the transit…
- Conditions
- Small Bowel Disease, Gastrointestinal Hemorrhage, Refractory Anemia
- Trial name
- NCT00275184
- Testing
- Senna, Citramag powder, Metoclopramide
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- London North West Healthcare NHS Trust
Obscure Gastrointestinal Bleeding (Occult or Overt)
Trial of Wireless Capsule Endoscopy in the Evaluation of Obscure Gastrointestinal Bleeding
This study compares wireless capsule endoscopy (patients swallow a pill-size camera that sends pictures of the intestine to a recorder worn on their belt) to an x-ray study (called dedicated small bowel contrast radiography) in…
- Trial name
- NCT01006824
- Testing
- Capsule endoscopy, Dedicated small bowel contrast radiography
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- University of Southern California
Iron Deficiency Anemia
Capsule Endoscopy vs Standard of Care for Obscure Intestinal Bleeding
The role of capsule endoscopy (CE) in patients with obscure / occult gastrointestinal (GI) bleeding remains unclear. This pragmatic randomized controlled trial is designed to determine the diagnostic yield and clinical outcomes…
- Trial name
- NCT00694954
- Testing
- Diagnostic Test - Given Imaging Pillcam, Diagnostics
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- University of Calgary
Occult Gastrointestinal Bleeding
Capsule Endoscopy vs. Push Enteroscopy in Occult Gastrointestinal Bleeding OGIB
Capsule endoscopy (CE) is a safe and effective tool for the assessment of obscure gastrointestinal bleeding (OGIB). However, its real efficacy and its position in the diagnostic algorithm of OGIB vs.
- Trial name
- NCT00224627
- Testing
- Capsule GIVEN IMAGING LTD
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthy Volunteers
Assessment of Gastrointestinal Blood Loss After Receiving Aspirin or Aspirin Plus Rivaroxaban, or Aspirin Plus REGN9933, or Aspirin Plus REGN7508 in Healthy Adult Participants
This study is researching experimental drugs called REGN9933 and REGN7508 (called "study drugs") and comparing their effects to approved treatments of rivaroxaban and aspirin (called "standard treatments").
- Trial name
- NCT06444178
- Testing
- Aspirin, REGN9933, REGN7508
- Where
- United Kingdom
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Gastrointestinal Bleeding, Complication of Internal Device
Occult Gastrointestinal Bleeding in Non-pulsatile Left Ventricular Assist Device(VAD)Patients
The purpose of this study is to estimate the proportion of Ventricular Assist Device (VAD) patients with abnormal gastrointestinal bleeding as assessed by HemoQuant fecal occult blood test.
- Trial name
- NCT01415869
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- Mayo Clinic
Occult Gastrointestinal Bleeding
Performance Value of Research of Occult Gastrointestinal Bleeding by Immunoassay in the Diagnostic Process of Iron Deficiency Anemia in Patients Over 75 Years
This study aims to characterize the diagnostic performance of immunological testing of occult gastrointestinal bleeding in stool in the population aged over 75 years with iron deficiency anemia.
- Trial name
- STRATAGANEMIE (NCT02727075)
- Where
- France
- Volunteers
- 79 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris