Clinical trials: Ocd
Obsessive-Compulsive Disorder
ITreatOCD: Predicting the Efficacy of Internet-based Cognitive Behavioral Therapy in Obsessive-compulsive Disorder
In the current study, the investigators will characterize obsessive-compulsive disorder (OCD) patients and healthy controls with a comprehensive clinical and neuroimaging assessment, focusing on the basic psychological processes…
- Trial name
- iTREATOCD (NCT05906069)
- Testing
- ICBT
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pedro Morgado
Major Depressive Disorder, Depression
Testing a Transdiagnostic TMS Treatment Target
The goal of this clinical trial is to test a new brain stimulation treatment target for individuals with depression plus at least one additional psychiatric disorder.
- Conditions
- Major Depressive Disorder, Depression, Psychiatric Disorder, Mood Disorders
- Trial name
- T5 (NCT06282146)
- Testing
- transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Brigham and Women's Hospital
PANDAS, Anxiety Disorder
Trial of Naproxen Sodium for the Treatment of OCD in Children With PANDAS
This project aims to rigorously evaluate a potential treatment for inflammation-related Obsessive-Compulsive Disorder (OCD) symptoms in children.
- Conditions
- PANDAS, Anxiety Disorder, Autoimmune Diseases, Obsessive-Compulsive Disorder
- Trial name
- NCT04015596
- Testing
- Naproxen Sodium
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Massachusetts General Hospital
Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood
Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder
Anxiety and obsessive-compulsive disorders are among the most common in children. Although cognitive behavioral therapy (CBT) is an effective and evidence-based treatment for such disorders, access to CBT is often limited.
- Conditions
- Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood, Social Anxiety Disorder of Childhood, Obsessive-Compulsive Disorder in Adolescence
- Trial name
- NCT05967468
- Testing
- Family Based, Internet-Based Cognitive Behavioral Therapy, Bibliotherapy, low therapist contact SPACE, Relaxation and Mentorship
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor College of Medicine
Obsessive-Compulsive Disorder
Cannabinoid Medication for Adults With OCD
The purpose of this pilot research study is to test the effects of a medication called nabilone (Cesamet) in adults with obsessive-compulsive disorder (OCD).
- Trial name
- NCT02911324
- Testing
- Nabilone, Exposure and Response Prevention Therapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- New York State Psychiatric Institute
Obsessive-Compulsive Disorder (OCD)
Feasibility of Modulating Cognitive Control in OCD
This study tests out procedures to look at whether a type of brain stimulation called transcranial magnetic stimulation impacts flexible shifts in behavior in obsessive-compulsive disorder (OCD).
- Trial name
- NCT07419009
- Testing
- continuous theta-burst transcranial magnetic stimulation (cTBS)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Obsessive-Compulsive Disorder
TMS for Improving Response Inhibition in Adolescents With OCD
The study will examine whether inhibition of the pre-supplementary motor area (pSMA) using transcranial magnetic stimulation (TMS) normalizes activity in pSMA-connected circuits, improves response inhibition, and reduces…
- Trial name
- NCT05104697
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Bradley Hospital
Obsessive-Compulsive Disorder, Anxiety Disorders
Efficacy of Exposure and Response Prevention(ERP) and SSRIs in Chinese OCD Patients
The purpose of this study is to evaluate the efficiency of SSRIs（Selective Serotonin Reuptake Inhibitor） ,ERP（Exposure and Response Prevention） and the combination of the two therapies for OCD(Obsessive-Compulsive Disorder)…
- Conditions
- Obsessive-Compulsive Disorder, Anxiety Disorders, Mental Disorders
- Trial name
- NCT02022709
- Testing
- Fluoxetine, Sertraline, Paroxetine
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Obsessive-Compulsive Disorder
Methods for Managing Intrusive Thoughts
The current study sought to translate laboratory research on learning and memory to better understand the mechanisms and methods for implementing exposure therapy for unwanted obsessional thoughts.
- Trial name
- NCT03416504
- Testing
- Gradual Exposure (EXP-G), Variable Exposure (EXP-V)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Obsessive-Compulsive Disorder, Social Anxiety Disorder
Neurobiological Markers of Treatment Response for Anxiety and OCD
Obsessive-compulsive disorder (OCD) and anxiety disorders are common and debilitating conditions which are often chronic when treatment is not provided.
- Conditions
- Obsessive-Compulsive Disorder, Social Anxiety Disorder, Panic Disorder
- Trial name
- NCT05663489
- Testing
- Bergen 4-Day Treatment (B4DT)
- Where
- Norway
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
OCD, Decision-Making
Arbitration Between Habitual and Goal-directed Behavior in Obsessive-compulsive Disorder: Circuit Dynamics and Effects of Noninvasive Neurostimulation
People utilize two behavioral strategies, goal-directed and habitual, when engaging in value-based decision-making that involves rewarding or punishing outcomes.
- Conditions
- OCD, Decision-Making, tDCS, fMRI
- Trial name
- NCT04075890
- Testing
- transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Obsessive-Compulsive Disorder
Neurocircuitry of Obsessive-Compulsive Disorder: Modulation by Transcranial Magnetic Stimulation
The purpose of this study is to test the effects of non-invasive neuromodulation, transcranial magnetic stimulation on brain function in individuals with obsessive-compulsive disorder (OCD).
- Trial name
- NCT02704117
- Testing
- Transcranial Magentic Stimulation
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Obsessive Compulsive Disorder
Fear Extinction and Mechanisms of Change in Obsessive Compulsive Disorder
The purpose of this study is to find out more about how the brain stores emotional learning in obsessive-compulsive disorder (OCD). In particular, we would like to understand how human beings learn not to fear.
- Trial name
- NCT02467374
- Testing
- Behavior Therapy
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obsessive-Compulsive Disorder
Neurofeedback for Obsessive-Compulsive Disorder (OCD)
The aim of this study is to train patients with obsessive-compulsive disorder to control a region of their brain that has been associated with their symptoms.
- Trial name
- NCT02206945
- Testing
- neurofeedback, control feedback
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Yale University
Obsessive-Compulsive Disorder
iTBS-DCS in Obsessive Compulsive Disorder
Obsessive Compulsive Disorder (OCD)is a common and debilitating illness. For an unacceptable proportion of patients, depressive symptoms remain impairing despite multiple treatments.
- Trial name
- NCT05177601
- Testing
- iTBS repetitive Transcranial Magnetic Stimulation (rTMS), D-cycloserine
- Where
- Canada
- Volunteers
- 81 people
- Sponsor
- University of Calgary
Obsessive-compulsive Disorder
Topiramate Augmentation in the Treatment of Obsessive-Compulsive Disorder
A 12-week program to examine the effectiveness of topiramate in adjunctive treatment for adults with obsessive-compulsive disorder and who are currently on serotonin reuptake inhibitor medications (ages 18-65).
- Trial name
- NCT00211744
- Testing
- topiramate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Montefiore Medical Center
OCD
Open/Aftercare Treatment for Participants Diagnosed With Obsessive Compulsive Disorder
The purpose of this study is to provide participants diagnosed with obsessive compulsive disorder (OCD) and completed one of the active study protocols at the Rodriguez Lab, with open/aftercare treatment.
- Trial name
- NCT03511534
- Testing
- Psychotherapy, Pharmacotherapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Stanford University
Obsessive-Compulsive Disorder
Neural Mechanisms of Obsessive-compulsive Disorder (OCD) Treatment Failure
The aim of this study is to understand why patients with obsessive-compulsive disorder (OCD) fail in therapy. To understand the neural mechanisms involved in exposure therapy that support success and clinical improvement in order…
- Trial name
- ERP in Silico (NCT05520398)
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- University College, London
Obsessive-Compulsive Disorder
Deep Brain Stimulation Surgery for the Treatment of Refractory Obsessive-Compulsive Disorder
This study will include two parts. The first part will include two patients in a non-blinded, non-randomized, open trial. They will undergo Deep Bran Stimulation (DBS) for OCD (targeting the amSTN), as clinically accepted and…
- Trial name
- NCT05995951
- Testing
- Deep Bran Stimulation (DBS)
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Rabin Medical Center
Obsessive-Compulsive Disorder
Internet-delivered CBT for Adolescents With OCD: A Randomized Controlled Study
The effect of Internet-delivered Cognitive Behavior Therapy (ICBT) on adolescents (12 to 17 years) with Obsessive-Compulsive Disorder is studied. Participants are randomized to either ICBT or a no-treatment condition.
- Trial name
- BiPOCD (NCT02191631)
- Testing
- Internet-delivered Cognitive Behavior Therapy
- Where
- Sweden
- Volunteers
- 67 people
- Sponsor
- Karolinska Institutet