Clinical trials: Ocular Prostheses
Outer Retinal Degeneration, Retinitis Pigmentosa
Argus® II Retinal Prosthesis System Post-Market Surveillance Study
This post-market surveillance study is conducted in the European Economic Area where Argus II has been CE certified for use in outer retinal degeneration patients.
- Trial name
- NCT01490827
- Where
- 10 sites in Germany, Italy
- Volunteers
- 52 people
- Sponsor
- Second Sight Medical Products
Retinitis Pigmentosa
The Perceptual Experience of Argus II Users
This Basic Experimental Studies Involving Humans (BESH) study investigates phosphene perception and performance factors in blind participants implanted with the Argus II retinal prosthesis system.
- Trial name
- NCT05285618
- Testing
- Argus II
- Where
- 3 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of California, Santa Barbara
Retinitis Pigmentosa
Observational Study of the Argus® II Retinal Prosthesis System
The Argus II Retinal Implant is a revolutionary new device, which offers vision to patients who are blind from retinal degeneration - retinitis pigmentosa. These patients have no alternatives.
- Trial name
- NCT01999049
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University Health Network, Toronto
Age Related Macular Degeneration
Study of WA-NG Telescope Prosthesis in Patients With End-stage Age-related Macular Degeneration
This is a pilot study to evaluate the safety of the Model WA-NG telescope prosthesis in patients with bilateral moderate to profound central vision impairment due to end-stage age-related macular degeneration.
- Trial name
- NCT01731964
- Testing
- Telescope prosthesis, WA-NG Telescope Prothesis
- Where
- Israel
- Sponsor
- VisionCare, Inc.
Retinitis Pigmentosa
Argus® II Retinal Stimulation System Feasibility Protocol
Investigational Phase of the Study: The objective of this feasibility study is to evaluate the safety and utility of the Argus II Retinal Stimulation System in providing visual function to blind subjects with retinitis…
- Trial name
- NCT00407602
- Testing
- Implant of Argus II Retinal Prosthesis
- Where
- 12 sites in United States, France and 3 more
- Volunteers
- 30 people
- Sponsor
- Second Sight Medical Products
Enucleated; Eye, Evisceration; Traumatic, Eye
Click2Print Artificial Eyes
To undertake a randomised crossover trial in human subjects the Click2Print ocular prosthesis versus an analogue ocular prosthesis demonstrating non-inferiority in the assessment of ocular prosthesis motility, cosmesis, fit and…
- Trial name
- Click2Print (NCT05093348)
- Testing
- Click2Print artificial eye, Hand-made artificial eye
- Where
- United Kingdom
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Total Knee Replacement, Optic Nerve Sheath Diameter Measurement
The Effect of Epidural Anesthesia on Optic Nerve Sheath Diameter Measurements in Total Knee Prosthesis Surgery
This study investigates the effects of epidural anesthesia on intracranial pressure (ICP) by using ultrasonographic optic nerve sheath diameter (ONSD) measurements as a non-invasive indicator.
- Conditions
- Total Knee Replacement, Optic Nerve Sheath Diameter Measurement, Intracranial Pressure Change
- Trial name
- NCT07458321
- Testing
- Bupivacaine %0.25 (isobaric), Bupivacaine %0.5 (hyperbaric)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Retinitis Pigmentosa
RETINA IMPLANT Alpha AMS in Blind Patients With Retinitis Pigmentosa
The goal of this study is to transfer the surgical implantation technique and evaluate the safety and effectiveness of the RETINA IMPLANT Alpha AMS to restore limited visual function and functional vision in blind Retinitis…
- Trial name
- NCT03629899
- Testing
- RETINA IMPLANT Alpha AMS
- Where
- United States
- Sponsor
- Wills Eye
Dry Age-related Macular Degeneration
Feasibility Study of Compensation for Blindness With the PRIMA System in Patients With Dry Age Related Macular Degeneration
In this study, the principle functionality of the device will be tested in humans for the first time. The study will evaluate the extent to which patients with atrophic dry age related macular degeneration (AMD) have evoked light…
- Trial name
- PRIMA FS (NCT03333954)
- Testing
- PRIMA Bionic Vision System
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Science Corporation
Age Related Macular Degeneration
Study of WA-NG Telescope Prosthesis in Patients With End-stage Age-related Macular Degeneration
This is a pilot study to evaluate the safety of the Model WA-NG telescope prosthesis in patients with bilateral moderate to profound central vision impairment due to end-stage age-related macular degeneration.
- Trial name
- NCT01361256
- Testing
- Telescope prosthesis, WA-NG Telescope Prothesis
- Where
- Israel
- Sponsor
- VisionCare, Inc.
Retinitis Pigmentosa, Choroideremia
Pilot Study of a Suprachoroidal Retinal Prosthesis
This study will be an initial proof of concept study, to evaluate safety and efficacy of a prototype suprachoroidal retinal implant
- Trial name
- NCT01603576
- Testing
- Prototype wide view suprachoroidal retinal prosthesis
- Where
- 2 sites in Australia
- Volunteers
- 3 people
- Sponsor
- Center for Eye Research Australia
Dry Eye
Eyelash Prostheses Compared to 5.0% Lifitegrast BID for Dry Eye Disease.
This is a single-center, randomized, controlled trial to evaluate the safety and efficacy of eyelash prostheses versus 5.0% Lifitegrast BID, in 40 patients (20 randomized to each of two arms of the study) evaluated at 3 weeks and…
- Trial name
- NCT03691636
- Testing
- Eyelash prostheses, 5.0% Lifitegrast Ophthalmic Solution
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- D.E.L., LLC
Inflammatory Reaction Due to Ocular Lens Prosthesis
Efficacy and Safety Study of IBI-10090 in Patients Undergoing Cataract Surgery
This study will test the efficacy and safety of IBI-10090 for the reduction of ocular inflammation after cataract surgery.
- Trial name
- NCT01048593
- Testing
- IBI-10090
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- ICON Bioscience Inc
Retinitis Pigmentosa, Choroideremia
Longitudinal Study of a Bionic Eye
This is a longitudinal observational study with participants who have been implanted with the suprachoroidal retinal prosthesis.
- Trial name
- NCT05158049
- Where
- Australia
- Volunteers
- 7 people
- Sponsor
- Center for Eye Research Australia
Blindness, Acquired
AI-Powered Artificial Vision for Visual Prostheses
Visual impairment is one of the ten most prevalent causes of disability and poses extraordinary challenges to individuals in our society that relies heavily on sight.
- Trial name
- NCT06117332
- Testing
- Visual prosthesis
- Where
- 2 sites in United States, Spain
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of California, Santa Barbara
Retinitis Pigmentosa
New Enrollment Post-Approval Study of the Argus® II Retinal Prosthesis System
This post-approval study is being implemented to monitor the use of Argus II System in a larger US population than available within pre-approval studies.
- Trial name
- NCT01860092
- Where
- 17 sites in United States
- Volunteers
- 53 people
- Sponsor
- Second Sight Medical Products
Pigmentary Retinopathy
Self-confidence Study in Patients With Argus II Artificial Retina
To evaluate whether the use of the Argus II retinal prosthesis improves the confidence and self-esteem of patients with advanced retinopathy pigmentosa
- Trial name
- NCT03510234
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Strasbourg, France
Ocular Inflammation, Ocular Prostheses
Comparison of Topical Treatment for Inflammatory Secretions of the Conjonctiva (Patients With Ocular Prostheses)
We propose to evaluate the efficacy of treatment with Hydrocortisone and Dexamethasone (in a cross-over design) in patients with ocular prostheses and significant functional discomfort.
- Trial name
- CRYSTAL (NCT05668455)
- Testing
- Hydrocortisone, Dexamethasone, Povidone
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Agnes
Retinitis Pigmentosa
Argus II/ORCAM Device Study
This study is being done to determine if wearable text-to-speech (TTS) and visual pattern recognition (VPR) technology can be used to extend the capabilities of the Argus II to allow patients to read and recognize faces and…
- Trial name
- NCT03248388
- Testing
- Argus II Eyeglasses, ORCAM
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Mayo Clinic
Blindness, Acquired
Early Feasibility Study of the Orion Visual Cortical Prosthesis System
This is an early feasibility study of a new device, the Orion Visual Cortical Prosthesis System. The device is intended to stimulate the surface of the visual cortex to induce visual perception in blind individuals.
- Trial name
- NCT03344848
- Testing
- Orion Visual Cortical Prosthesis System
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Second Sight Medical Products