Clinical trials: Ocular Refraction
Keratoconus, Alteration of Visual Acuity
CHOICE OF SUBJECTIVE OCULAR REFRACTION TECHNIQUE AND CORNEAL TOPOGRAPHY OF KERATOCONUS
Keratoconus is a rare evolving corneal ectasia that alters visual acuity. To improve spectacle-corrected visual acuity, various subjective refraction techniques can be used.
- Trial name
- RE-CON (NCT04174209)
- Testing
- Cylinder, Dial, Slit
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Clermont-Ferrand
Myopia Progression, Atropine
Efficacy and Safety of 0.01%, 0.03%, and 0.05% Atropine Eye Drops in Reducing Myopia Progression
Myopia is one of the fastest-growing ocular disorders worldwide and has become a major public health concern, especially among children and adolescents.
- Trial name
- NCT07626892
- Testing
- Atropine sulphate eye drop 0.01%, Atropine sulphate eye drop 0.03%, Atropine sulphate eye drop 0.05%
- Where
- Pakistan
- Volunteers
- 95 people
- Sponsor
- Khyber Medical College, Peshawar
Intraocular Lens Implantation, Cataract
Intraoperative Aberrometry vs Conventional Intraocular Lens Calculation, a Prospective Study.
the goal of this intervention study is to compare prospectively the accuracy of the power calculation between both groups, the intraoperative aberrometry (ORA) vs barrett universal II preoperative calculation (control group) .
- Conditions
- Intraocular Lens Implantation, Cataract, Humans, Ocular, Refraction
- Trial name
- ORAVSCTRL (NCT06219252)
- Testing
- Intraoperative aberrometer, Preoperative intraocular lens calculation
- Where
- Mexico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Myopia, Hyperopia
Comparing Low-cost Handheld Autorefractors - a Practical Approach to Measuring Refraction in Low Resource Settings
Study compares four portable vision measurement and eye-imaging technologies in terms of accuracy and time and ease of use with older adult (ages 40-100) participants in a developing-country setting (India).
- Trial name
- NCT03456245
- Testing
- Vision device validation
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
General Anesthesia
Comparison of Refraction Measurments in Children Under General Anesthesia, With and Without Cycloplegic Drops
Assessment of refraction measurements in children under general anesthesia, with or without cyclopelgic eye-drops
- Trial name
- NCT02459600
- Testing
- instulling cyclopentolate drops in the eye
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Soroka University Medical Center
Myopia
Validation of the Vision Trainer Clinical Decision-Support Software
This study is a prospective, randomized, crossover clinical investigation designed to evaluate the accuracy, efficiency, and usability of the Vision Trainer software for subjective refraction.
- Trial name
- NCT07773753
- Testing
- Software Trainer
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Pennsylvania
Myopia
The Children's WEAR Trial(Phase 1&2)
Phase I: Focus groups on different designs of adjustable glasses and standard glasses (August-September 2012) Phase II: Two-month randomized trial comparing four groups: (September 2012 - August 2013)
- Trial name
- WEAR (NCT01704729)
- Testing
- group1, group2, group3
- Where
- China
- Volunteers
- 2,300 people
- Sponsor
- Sun Yat-sen University
Autoimmune Diseases, Inflammatory Diseases
Prospective Observational Study Evaluating the Safety and Efficacy of Immunomodulatory Therapies in Refractory Inflammatory and Autoimmune Diseases
Inflammatory and/or autoimmune diseases represent a very broad group of diseases with highly variable clinical features, including - but not limited to - systemic connectivites and vasculitides.
- Trial name
- ARIES (NCT06757426)
- Where
- 17 sites in France
- Volunteers
- 80 people
- Sponsor
- Groupe français d'étude des Maladies Inflammatoires de loeil
Children Aged 3-5 Years, Vision Screening
Shared Reading for Pediatric Ophthalmic Education
We use generative AI to make personalized books for young children about going to the eye doctor. We want to see if reading these stories helps kids feel more comfortable and improves their overall experience at the clinic.
- Conditions
- Children Aged 3-5 Years, Vision Screening, Cycloplegic Refraction
- Trial name
- NCT07590791
- Testing
- Generative AI-customized educational book, standard printed educational leaflet, Commercially available children's book
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Myopia, Child Myopia Progression
Effect of MiYOSMART iQ Spectacle Lenses on Myopia Progression in Children
This prospective, single-center study aims to evaluate the efficacy and safety of MiYOSMART iQ spectacle lenses with DIMS (Defocus Incorporated Multiple Segments) and Triple Enhanced Design (TED) technology in slowing myopia…
- Trial name
- NCT07387159
- Testing
- MiYOSMART iQ spectacle lenses
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- Hoya Lens Rus LLC
Tomography, Visual Acuity
Keratoconus - Screening in Patients With Downs Syndrome
The initial purpose of the study is to determine the true tomographic based age-specific prevalence of keratoconus among Danish patients with Downs Syndrome.
- Conditions
- Tomography, Visual Acuity, Refraction Error
- Trial name
- NCT07800975
- Where
- Denmark
- Volunteers
- 137 people
- Sponsor
- University of Aarhus
Refractive Errors
Consistency of an Automated Subjective Refraction Program Between Personnel With Diverse Professional Backgrounds and Senior Optometrists
This study aims to evaluate the performance of automated subjective refraction performed by operators with different professional backgrounds.
- Trial name
- NCT07891884
- Testing
- Nurse-Operated Automated Subjective Refraction, Village Doctor-Operated Automated Subjective Refraction, Lay Personnel-Operated Automated Subjective Refraction
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Hyperopia, Hypermetropia
Enhancement of Emmetropization in Hyperopic Infants
To determine if wearing a moderate spectacle under-correction (3.00D) and performing activities designed to stimulate accurate accommodation during a 15-month period will enhance emmetropization in highly hyperopic (between…
- Conditions
- Hyperopia, Hypermetropia, Farsightedness
- Trial name
- NCT00574717
- Testing
- Spectacles
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Ohio State University
Posterior Capsule Opacification
Refraction Changes After Using ND: YAG LASER In Treatment of Posterior Capsular Opacification In Pseudo Phakic Eye
The most prevalent long term consequence of cataract surgery in both phacoemulsification and extracapsular cataract excision is posterior capsular opacification (PCO) PCO occurred in 11.8 percent of patients one year after…
- Trial name
- NCT05501535
- Testing
- ND:YAG LASER
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Refraction Error, Myopia
Age and Refraction in Predicting Myopia Progression in COVID-19
To determine the longitudinal changes of age and refraction in predicting myopia progression with risk under the coronavirus disease 2019 (COVID-19) pandemic in a 3-year follow-up of a Chinese cohort.
- Trial name
- NCT05305274
- Testing
- screening
- Where
- China
- Volunteers
- 34,400 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Cataract, Astigmatism
Toric Intraocular Lens Following Cataract Surgery
The objective of this clinical trial is to evaluate the safety and effectiveness of the Bausch + Lomb Toric Accommodating Posterior Chamber Silicone Intraocular Lens used to provide near, intermediate, and distance vision and a…
- Trial name
- NCT01140477
- Testing
- Toric Accommodating Lens, Accommodating Lens
- Where
- United States
- Volunteers
- 229 people
- Sponsor
- Bausch & Lomb Incorporated
Longitudinal Chromatic Aberration, Blue Light Defocus Manipulation
Application and Clinical Evaluation of Longitudinal Chromatic Aberration Technique in Ophthalmology
Our study aims to delve into the effects of shifting the focal point of blue light from video or text displayed on a terminal screen forward on the axial length of the eye, ocular blood flow, visual fatigue, and visual function…
- Trial name
- NCT06449976
- Testing
- blue light defocus and blue light filtering
- Where
- China
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Individuals With Eye Refraction Defects
The Effect of Eye Exercises in Individuals With Eye Refractive Defects
According to the World Health Organization's statement published in 2014, 43% of visual impairment is overhauled by uncorrected refractive errors.
- Trial name
- NCT05999552
- Testing
- Eye exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Refractive Errors, Vision Disorders
Handheld Device Compared With a Standard Eye Care Diagnostic Device in Measuring Ophthalmic Refraction
This study is exploratory and examines whether the best-corrected visual acuities (BCVA's) from trial frames created with the refraction results obtained from a novel handheld optical device yields results similar to the…
- Trial name
- NCT04693247
- Testing
- EQ103
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Refractive Error
Proof of Concept Study for First-Sight Refractive Error Correction: Direct Comparison to Manifest Refraction and Autorefraction Results
Proof of concept study is to compare the best corrected visual acuity obtained via First-Sight lenses with the clinical "gold standard" of manifest refraction and autorefraction.
- Trial name
- NCT01342393
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Nebraska