Clinical trials: Oculomotor System
Ataxia, Spinocerebellar Ataxias
Transcranial Alternating Current Stimulation (tACS) in Patients With Ataxia
The aim of the study is to evaluate the effects on motor and cognitive performance of transcranial alternating current stimulation (tACS) compared to transcranial direct current stimulation (tDCS) and placebo stimulation (sham)…
- Conditions
- Ataxia, Spinocerebellar Ataxias, Multiple System Atrophy, Ataxia With Oculomotor Apraxia
- Trial name
- SCAtACS (NCT05621200)
- Testing
- Transcranial stimulation over the cerebellar hemispheres
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Corticobasal Degeneration (CBD), Corticobasal Syndrome (CBS)
4-Repeat Tauopathy Neuroimaging Initiative - Cycle 2
The goal of this study is to identify the most reliable methods of analysis for tracking CBD, PSP, and o/vPSP over time. The results from this study may be used in the future to calculate statistical power for clinical drug…
- Conditions
- Corticobasal Degeneration (CBD), Corticobasal Syndrome (CBS), Cortical-basal Ganglionic Degeneration (CBGD), Progressive Supranuclear Palsy (PSP)
- Trial name
- 4RTNI-2 (NCT02966145)
- Testing
- Observational Study
- Where
- 8 sites in United States, Canada
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy
Normative Oculomotor and Vestibular Data in Pediatric Population
The purpose of this study is to use a device called I-Portal® Portable Assessment System (I-PAS) to record eye movements in response to a number of visual and auditory stimuli designed to evaluate neural brain pathways related to…
- Trial name
- NCT04107610
- Testing
- I-PAS
- Where
- 2 sites in United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Neurolign
Parkinson Disease
" Visual Characterization of Parkinson's Patients and Oculomotor or Perceptual Therapy"
Parkinson's disease (PD) is the second most common neurodegenerative condition worldwide, characterised by motor symptoms, but with other symptoms such as visual impairment.
- Trial name
- NCT06032130
- Testing
- Clinical measurements, Oculomotor or perceptual therapy
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Migraine Without Aura
Myotensive Extraocular Muscle Techniques Added to Manual Therapy for Migraine Without Aura
Migraine without aura is a highly prevalent and disabling primary headache that significantly affects quality of life. Many patients experience insufficient symptom control with pharmacological treatments or develop adverse…
- Trial name
- NCT07254598
- Testing
- Myotensive Extraocular Muscle Techniques + Manual Therapy, Standard Manual Therapy
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Facultad de Enfermería, Fisioterapia y Podología (FEFP)
Strabismus
Strabismus Measurements Using Automated 3D Video Oculography
Measuring ocular motility and alignment is important for diagnosing different causes of strabismus, following patients recovering from cranial nerve palsies, preparing patients for strabismus surgery and follow-up post surgery.
- Trial name
- NCT02228070
- Testing
- strabismus video goggles
- Where
- Switzerland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Concussion, Brain
Oculomotor Function Testing in Acute Concussion
This is a prospective longitudinal study which aims to compare oculomotor function and visual scanning behaviour (VSB) of participants who suffered concussion with healthy controls with no concussion.
- Trial name
- NCT03892356
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
Benign Paroxysmal Positional Vertigo (Disorder)
Oculomotor and Vestibular Ocular Reflex Exercises in Patients With Benign Paroxysmal Positional Vertigo
The aim of this research is to assess effects of Oculomotor and VOR exercises on vertigo, dizziness and balance in patients with BPPV. Randomized controlled trial was conducted at Hameed Latif Hospital, Lahore.
- Trial name
- NCT05333198
- Testing
- Traditional physical therapy using Epley's maneuver, Oculomotor and Vestibular Ocular Reflex (VOR) exercises
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Mild Traumatic Brain Injury (mTBI), Sports-related Concussion
Mobile Dual-Task Brain and Balance Intervention for Concussion Recovery
This research study examines recovery after a sports-related concussion or mild head injury. Many athletes experience lingering problems with thinking, balance, and mood months after a concussion.
- Conditions
- Mild Traumatic Brain Injury (mTBI), Sports-related Concussion, Heart Rate Variability (HRV), Walking
- Trial name
- NCT07599475
- Testing
- Home-Based Mobile Dual-Task Intervention (BraW-Day™)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hyunhwa Lee
Diabetic Neuropathies
Eye-tracking-based Artificial Intelligence Detects Abnormalities of the Oculomotor System in Type 1 Diabetes
Abnormalities of the oculomotor system may represent an early sign of diabetic neuropathy and are currently poorly studied. The investigators designed an eye-tracking-based test to evaluate the oculomotor function in patients…
- Trial name
- EyekonT1D (NCT04608890)
- Testing
- Eye-tracking video test
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Milan
Convergence Insufficiency
Natural History of MTBI-related Convergence Insufficiency & Effectiveness of Vision Therapy for MTBI-related CI
The design of this project is a pilot study, a type of feasibility study conducted in preparation for subsequent RCTs that will assess the effectiveness of office-based vergence/accommodative therapy with movement (OBVAM) for…
- Trial name
- TBEye (NCT06848673)
- Testing
- Office-Based Vergence/Accommodative Therapy with Movement (OBVAM)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Salus University
Parkinson Disease
Development of Digital Diagnostic Devices for Parkinson's Disease
In this project, ocular motor, pupil and gait data in people with Parkinson's disease (PD) will be collected in order to develop machine learning models for the diagnosis and monitoring of PD.
- Trial name
- NCT06663826
- Testing
- oculomotor and pupillary function assessment
- Where
- Switzerland
- Volunteers
- 116 people
- Sponsor
- machineMD AG
Concussion, Mild, Concussion, Intermediate
Assessment of Oculomotor, Vestibular and Reaction Time Response Following a Concussive Event
This study is designed to evaluate the use of a collection of tests that measure the eye response, balance, oculomotor and reaction time tests to aid in the diagnosis of mTBI.
- Conditions
- Concussion, Mild, Concussion, Intermediate, Concussion, Severe
- Trial name
- NKI-RIF1 (NCT01832714)
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Neurolign
Postural Balance, Gait Analysis
Acute Effects of Oculomotor Exercises on Posturography and Gait Analysis Parameters in Regular Exercisers
This study aims to investigate the acute effects of a single-session oculomotor exercise program on static posturography and gait analysis parameters in healthy individuals who exercise regularly.
- Conditions
- Postural Balance, Gait Analysis, Oculomotor System, Exercise
- Trial name
- OMEX-PG (NCT07718282)
- Testing
- Oculomotor Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ege University
Sleep Quality, Older Adults (65 Years and Older)
Effect of Health Promotion Model-Based Oculomotor Exercise Program on Sleep Quality in Older Adults
The goal of this clinical trial is to investigate the effect of a Health Promotion Model-based oculomotor exercise program on sleep quality among older adults living in a nursing home.
- Trial name
- NCT07261124
- Testing
- Oculomotor Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Ocular Motility Disorders
Oculomotor Training Improves Reading Eye Movement
Children with reading eye movement problems were recruited for this study. The treatment group was provided with oculomotor training for 8 weeks, the control group was given placebo exercises.
- Trial name
- NCT02981875
- Testing
- oculomotor training
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Stroke, Vertigo
Telemedical Examination of a Three-Component Oculomotor Testing Battery
The study investigates the feasibility and safety of the telemedical implementation of three diagnostic oculomotor tests using a video-oculography device and an extended teleconferencing system.
- Conditions
- Stroke, Vertigo, Dizziness
- Trial name
- NCT02938221
- Testing
- Telemedical video-oculography system
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Munich Municipal Hospital
Nystagmus, Dizziness
Effects of Cervical and Oculomotor Exercises in Young Adults With Benign Paroxysmal Positional Vertigo
Benign paroxysmal positional vertigo (BPPV) is the most common type of dizziness disorder in the community.Its cardinal symptoms include vertigo which is induced by change in position of head, turning over in bed, looking up…
- Trial name
- NCT07587528
- Testing
- Occulomotor exercises, Cervical Exercises
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Foundation University Islamabad
Extraocular Muscle Disorder, Neuromuscular Diseases
Oculomotor Training and Chinese Characters Recognition in Children With Neuromuscular Disease
The aim of this study is to investigate the effects of gaze-directed oculomotor training incorporated with web-based curriculum readings in Chinese to enhancing fixation, saccade and Chinese characters recognition in…
- Trial name
- yes (NCT03627962)
- Testing
- gaze-directed oculomotor training
- Where
- Hong Kong
- Volunteers
- 21 people
- Sponsor
- The Hong Kong Polytechnic University
Septo-Optic Dysplasia, Agenesis of Corpus Callosum
Sleep Profile of Patients With Septo-optic Dysplasia
The aim of this study is to evaluate sleep of patients with septo-optic dysplasia compared to patients with an isolated disorder of peripheral visual system and patients with corpus callosum agenesis since both visus defict and…
- Conditions
- Septo-Optic Dysplasia, Agenesis of Corpus Callosum, Blindness
- Trial name
- NCT06262152
- Testing
- Actigraphy, blood and salivary sample, and sleep evaluation
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation