Clinical trials: Oesophageal Cancer Nos
Esophagectomy, Esophageal Cancer
Non-gastric Conduit Reconstruction After Esophagectomy
This study is to collect and analyze the clinical information of patients who underwent reconstruction using conduits other than the stomach, such as the colon and small intestine, after esophagectomy.
- Trial name
- NCT07064655
- Volunteers
- 25 people
- Sponsor
- Samsung Medical Center
Esophageal Cancer, Lung Cancer
Thoracic Surgery Combined With Intrathoracic Hyperthermic Perfusion for Advanced Lung Cancer / Esophageal Cancer
The goal of this clinical research study is to explore whether intrathoracic hyperthermic perfusion after radical surgery could reduce local recurrence rate(13%) for advanced lung cancer / esophageal cancer.
- Conditions
- Esophageal Cancer, Lung Cancer, Hyperthermic Perfusion
- Trial name
- NCT03110939
- Testing
- hyperthermic perfusion
- Where
- China
- Sponsor
- Henan Cancer Hospital
Esophageal Adenocarcinoma
Upfront Chemotherapy With Radiation Therapy (CRT) Followed by Chemotherapy in Localized Esophageal Adenocarcinoma
The goal of this trial is to learn if adding consolidative chemotherapy to routine chemoradiation can better control both local recurrence and metastasis and reduce the need for surgical intervention.
- Trial name
- TNT Esophagus (NCT07603375)
- Testing
- FOLFOX (5-fluorouracil, Leucovorin, Oxaliplatin)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Colon Cancer, Stomach Tumor
Implementation of Pre-emptive Geno- and Phenotyping in 5-Fluorouracil- or Capecitabine-treated Patients
The aim of this study is to investigate if the systematic implementation of pre-emptive geno- and phenotyping, and therefore a dose reduction based on the French guidelines and the literature during the first month of treatment…
- Conditions
- Colon Cancer, Stomach Tumor, Anal Tumor, Pancreas Cancer
- Trial name
- NCT04269369
- Testing
- 5-Fluorouracil
- Volunteers
- 250 people
- Sponsor
- Jessa Hospital
Esophageal Cancer
Comparing ICI Followed By CCRT And CCRT Followed By Immunotherapy In Unresectable LA-ESCC
A total of 120 patients with unresectable, locally advanced esophageal squamous cell carcinoma patients will be enrolled in this study and randomly divided into two groups.
- Trial name
- NCT07733830
- Testing
- Adebrelimab, Nab paclitaxel, Carboplatin
- Where
- 7 sites in China
- Volunteers
- 120 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Esophageal Cancer, Drainage/Methods
Comparison of Drainage Methods in Minimally Invasive Esophagectomy (DEMURE）
This RCT compares three drainage approaches after minimally invasive esophagectomy (chest tube + thoracic mediastinal drainage tube, thoracic, and abdominal mediastinal drainage tube) to evaluate perioperative outcomes…
- Conditions
- Esophageal Cancer, Drainage/Methods, Postoperative Pain
- Trial name
- NCT07004634
- Testing
- Chest mediastinal tube, Abdominal mediastinal tube, Chest tube + chest mediastinal tube
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Ruijin Hospital
GORD, Oesophageal Cancer
The Bacterial Composition of the Stomach in Reflux Disease
Gastric and oesophageal (OG) cancer associated with poor long term outcome as overall less than 25% of patients survive for more than 5 years due to late recognition of the disease.
- Conditions
- GORD, Oesophageal Cancer, Oesophageal Reflux, Gastric Cancer
- Trial name
- NCT03835663
- Testing
- No intervention but patients are undergoing an upper GI endoscopy and biopsies for clinical purposes
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Imperial College London
Esophageal Neoplasm
Study for Determination of Feasibility and Toxicity of Pre-Treatment With HPPH (2-1[1-Hexyloxyethyl]-2 Devinyl Pyropheophorbide-a) Photodynamic Therapy Prior to Chemoradiation in Non-Operable Patients With Obstructive Esophageal Cancer
This study aim is to find out what effects capecitabine, oxaliplatin and radiation therapy following photodynamic therapy have on esophageal cancer.
- Trial name
- NCT01035437
- Testing
- HPPH 2-1[1-hexyloxyethyl]-2-devinyl Pyropheophorbide-a)
- Sponsor
- Roswell Park Cancer Institute
Esophageal Cancer
A Pilot Study of the Effectiveness of Acceptance and Commitment Therapy With a Post-Upper GI Cancer Population
This pilot research study aims to assess the effectiveness of an Acceptance and Commitment Therapy (ACT; Hayes Strosahl \& Wilson, 2011) group based intervention at improving quality of life (QOL) and increasing Psychological…
- Trial name
- NCT02491372
- Testing
- Acceptance and Commitment Therapy
- Sponsor
- Martin Dempster
Esophageal Cancer
Positron Emission Tomography in Determining Stage of Esophageal Cancer
RATIONALE: Imaging procedures such as positron emission tomography may improve the ability to determine the stage of esophageal cancer.
- Trial name
- NCT00004867
- Testing
- conventional surgery, positron emission tomography, radionuclide imaging
- Where
- 35 sites in United States
- Volunteers
- 235 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Esophageal Cancer, Precancerous Condition
Erlotinib in Treating Patients With Barrett Esophagus
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming. Erlotinib may keep esophageal cancer from forming in patients with Barrett esophagus by blocking some of the enzymes needed for cell growth.
- Trial name
- NCT00566800
- Testing
- erlotinib hydrochloride, laboratory biomarker analysis, biopsy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Kansas City Veteran Affairs Medical Center
Esophageal Cancer
Volume Outcome Relationships and Effects
This is a retrospective analysis to assess if high-volume hospital facilities experience greater or lesser rates of incidence in patients with esophageal cancer than low-volume facilities.
- Trial name
- NCT06343597
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Methodist Health System
Stomach Neoplasms, Esophageal Neoplasms
Safety and Efficacy of G17DT Immunogen in the Treatment of Gastric and Gastroesophageal Cancer
This study will test whether the G17DT Immunogen, when administered in combination with chemotherapy, is an effective and safe treatment for gastric cancer.
- Trial name
- NCT00042510
- Testing
- Treatment group
- Volunteers
- 103 people
- Sponsor
- Cancer Advances Inc.
Esophageal Neoplasm, Rectal Neoplasms
Prospective Study Evaluating the Feasibility of Fiducial Markers Placement for Patients With Esophageal or Rectal Cancer
It is a multicenter prospective observational study including consecutive patients with esophageal tumor or rectum with indication for radiotherapy The main objective of this study is to evaluate the feasibility of fiducial…
- Trial name
- FIDECHO (NCT03057288)
- Testing
- fiducial markers placement
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Société Française d'Endoscopie Digestive
Esophageal Squamous Cell Cancer, Adenocarcinoma of Esophagogastric Junction, Gastric Adenocarcinoma
Tucidinostat Plus PD-1 Inhibitor and Bevacizumab for Advanced Esophagus Cancer, AEG, Gastric Cancer
This Phase II study was designed to assess the efficacy and safety of the combination of PD-1 inhibitor, Tucidinostat (chidamide), a histone deacetylase inhibitor, and bevacizumab in advanced Esophageal squamous cell cancer…
- Trial name
- NCT05163483
- Testing
- Tucidinostat (chidamide), PD-1 inhibitor (Toripalimab), Bevacizumab
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Ruihua Xu
Esophageal Cancer
Cisplatin, Irinotecan, and Radiation Therapy in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer That Can Be Removed By Surgery
This phase II trial studies how well giving cisplatin and irinotecan hydrochloride together with radiation therapy works in treating patients with esophageal cancer or gastroesophageal junction cancer that can be removed by…
- Trial name
- NCT00316862
- Testing
- cisplatin, irinotecan hydrochloride, therapeutic conventional surgery
- Where
- 24 sites in United States
- Volunteers
- 82 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Gastric Cancer (GC) Gastroesophageal Junction Cancer (GEJ)
Continuation of Serplulimab Plus Chemotherapy After First Progression in Advanced Gastric or Gastro-oesophageal Junction Adenocarcinoma: an Open-label, Randomised Phase II Trial
This study is conducted in patients with advanced metastatic gastric cancer including gastroesophageal junction cancer(patients with HER2 negative and PD-L1 CPS≥5).Patiens will recevie Serplulimab plus chemotherapy…
- Trial name
- NCT05942573
- Testing
- Serplulimab+Paclitaxel+Apatinib, Paclitaxel±Ramucirumab
- Where
- China
- Volunteers
- 107 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Gastric Cancer
Trial of Panitumumab Cisplatin, Fluourouracil and Docetaxel in Locally Advanced or Metastatic Gastric Cancer
Investigators propose to study the effect of panitumumab when combined with an active regimen, such as DCF (Docetaxel/Cisplatin/Fluourouracil), in previously untreated patients with advanced cancer of the stomach.
- Trial name
- NCT01716546
- Testing
- Pazopanib
- Where
- 9 sites in Greece
- Volunteers
- 51 people
- Sponsor
- Hellenic Oncology Research Group
Gastric Cancer, Esophageal Cancer
Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Gastroesophageal Cancers
GENCONCOR-2 is a translational research aimed to compare the molecular profile of primary tumors and their matched brain metastases in gastroesophageal cancers, including cancer of the esophagus, gastroesophageal junction, and…
- Conditions
- Gastric Cancer, Esophageal Cancer, Brain Metastases
- Trial name
- GENCONCOR-2 (NCT07464470)
- Testing
- HER2 Testing, MSI Testing, PD-L1 Testing
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Blokhin's Russian Cancer Research Center
Gastric Cancer, Esophageal Cancer
PAN-study: Pan-Cancer Early Detection Study (PAN)
The PAN-cancer Early Detection study or PAN-study is a prospective cross-sectional observational case-control study evaluating whether Breath Biopsy can differentiate between patients with and without different cancer types by…
- Conditions
- Gastric Cancer, Esophageal Cancer, Liver Cancer
- Trial name
- NCT03756597
- Testing
- ReCIVA, CASPER
- Where
- United Kingdom
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Owlstone Ltd
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