Clinical trials: Older Adults With Mild Neurocognitive Disorders
Mild Cognitive Impairment, Dementia
Multi-modal Large Language Model-Empowered Talk Therapy for Older Adults With ADRD
The purpose of this study is to test the usefulness and the effect of Smart Virtual Reminiscence (SVR) therapy intervention on the Behavioral and Psychological Symptoms of Dementia (BPSD) of patients with Alzheimer's Disease and…
- Conditions
- Mild Cognitive Impairment, Dementia, BPSD, BPSD (Behavioral and Psychological Symptoms of Dementia)
- Trial name
- SVR (NCT07499570)
- Testing
- Smart Virtual Reminiscence Therapy, Music Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Indiana University
Mild Cognitive Impairment
Measuring the Impact of a Socially Assistive Robot
Due to increasing age and an increasing prevalence rate of neurocognitive disorders such as Mild Cognitive Impairment and dementia, independent living may become challenging.
- Trial name
- NCT04848155
- Testing
- socially assistive robot
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Ghent
Mild Cognitive Impairment (MCI), Depressive Symptoms
rTMS Combined With Aerobic Exercise for Older Adults With Mild Cognitive Impairment and Comorbid Depression
This study aims to evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) and aerobic exercise on cognitive function and mental health in older adults with mild cognitive impairment (MCI) and comorbid…
- Trial name
- NCT07652775
- Testing
- Repetitive Transcranial Magnetic Stimulation, Aerobic Exercise
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Cheng-Hsin General Hospital
Mild Cognitive Impairment, Dual Task
The Activation and Walking Speed of the Prefrontal Cortex of the Elderly Mild Cognitive Impairment During Dual Task.
The goal of this observational study is to compare to investigate the effect of dual task performance on straight and curved walking in elderly people with mild cognitive impairment.
- Trial name
- NCT05885867
- Testing
- Seniors with mild cognitive impairment over 65 years of age
- Where
- South Korea
- Volunteers
- 27 people
- Sponsor
- Sahmyook University
Mild Cognitive Impairment
Facilitating Optimal Routines in Aging
Loss of cognitive abilities leading to Alzheimer's disease is progressive and destructive, leaving older adults disabled and unable to recall their past.
- Trial name
- ForAging (NCT03913637)
- Testing
- Strategy Training, Enhanced Usual Care
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Pittsburgh
Mild Cognitive Impairment
Acupoint Massage and Aromatherapy Intervention in Elderly People With Mild Cognitive Impairment in Nursing Institutions
This study aims to investigate and compare the intervention effects of acupressure,aromatherapy,combining acupressure and aromatherapy in elderly with mild cognitive impairment.
- Trial name
- NCT03857269
- Testing
- Acupoint Massage, lavender essential oil, Acupoint Massage and lavender essential oil
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Huan Ding
Dementia, Mild Cognitive Impairment (MCI)
Early-Stage Partner in Care Living Alone Plus
EPICLA+ (Early-Stage Partners in Care Living Alone Plus) is a research project designed to assist people with early-stage memory loss who live alone in the community by providing early-stage related education and skill-training…
- Conditions
- Dementia, Mild Cognitive Impairment (MCI), Alzheimer Disease
- Trial name
- EPICLA+ (NCT06962111)
- Testing
- Psychoeducational skills training intervention
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Arizona State University
Mild Neurocognitive Disorder
Effectiveness of a Novel Exergame-Based Training Concept for Older Adults With Mild Neurocognitive Disorder
BACKGROUND: Simultaneous motor-cognitive training interventions are considered promising to prevent the decline in cognitive functioning in older adults with mild neurocognitive disorder (mNCD) and can be highly motivating when…
- Trial name
- NCT05387057
- Testing
- Exergame training according to the 'Brain-IT' exergame-based training concept, Usual Care
- Where
- Switzerland
- Volunteers
- 41 people
- Sponsor
- Eling DeBruin
Lifestyle, Cognitive Decline
Brain-Health Lifestyle Restructuring Intervention
With population aging, the number of older persons with cognitive impairments increases. Literature support the effectiveness of a lifestyle approach to promote the health of persons with cognitive impairment, as well as a…
- Conditions
- Lifestyle, Cognitive Decline, Aging
- Trial name
- NCT04576624
- Testing
- Lifestyle Intervention, social activity
- Where
- Taiwan
- Volunteers
- 125 people
- Sponsor
- National Cheng Kung University
Feasibility Randomized Control Trial
Mindfulness-Based Stress Reduction With Older Adults Living With Cognitive Impairment in Primary Care.
People living with subjective cognitive decline (SCD) or mild cognitive impairment (MCI) experience less efficiency in performing complex everyday tasks, which may result in a general sense of discontentment and decreased…
- Trial name
- NCT03867474
- Testing
- Mindfulness-Based Stress Reduction (MBSR)
- Where
- 2 sites in Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Mild Cognitive Impairment
Effects of Multimodal Music Intervention on Mild Cognitive Impairment Elderly
The goal of this clinical trial is to learn about whether music therapy can ameliorate cognitive function, physical fitness and psychology in mild cognitive impairment and mild dementia population.
- Trial name
- NCT06324227
- Testing
- multimodal music therapy, no intervention
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Yang Ming Chiao Tung University
Mild Cognitive Impairment, Alzheimer Disease
Study of the Efficacy and Safety of Various Anti-inflammatory Agents in Participants With Mild Cognitive Impairment or Mild Alzheimer's Disease
The purpose of this platform study was to evaluate the effect of anti-inflammatory agents on cognition in early Alzheimer's disease.
- Trial name
- NCT04795466
- Testing
- Canakinumab
- Where
- 10 sites in United States, Finland and 2 more
- Volunteers
- 34 people
- Sponsor
- Novartis Pharmaceuticals
Alzheimer's Disease, Mild Cognitive Impairment
Brain-Computer Interface System for Training Memory and Attention in Elderly
The primary objective is to examine the efficacy of 8-weeks of a locally developed brain-computer interface based system intervention for improving attention and memory in healthy elderly and those with age related cognitive…
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Age-Related Cognitive Decline, Dementia
- Trial name
- NCT02228187
- Testing
- Brain-Computer Interface
- Where
- Singapore
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Mild Cognitive Impairment, Randomized Controlled Trial
Cognitive Stimulation in Older With Mild Cognitive Impairment
The participants who carry out our program of cognitive stimulation, deteriorate at a cognitive level more slowly and can improve their score of the Spanish version of 35 points of Mini-mental State of Folstein; Mini-exam…
- Trial name
- Cognitive (NCT03831061)
- Testing
- Cognitive stimulation
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Parkinson's Disease with Cognitive Impairment, Healthy Elderly
Effectiveness of Attention/executivefunctions Training on Prospective Memory Abilities of Parkinson's Disease Subjects with Mild Cognitive Impairment and Healthy Aged Individuals: a Placebo-controlled Study with a Combined Immersive Virtual Reality and Telemedicine Approach
The goal of this randomized controlled trial is to evaluate the efficacy of attention and executive function training on prospective memory (PM) and executive functions in patients with Parkinson's disease and mild cognitive…
- Trial name
- NCT06801782
- Testing
- Experimental Cognitive training in Immersive Virtual Reality and Telemedicine approach, Active Comparator #1
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Insomnia, Cognitive Dysfunction
Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND)
This randomized controlled trial will evaluate the impact of an Internet-delivered cognitive behavioral therapy for insomnia (CBT-I) intervention on sleep and the extent to which it contributes to cognitive health in individuals…
- Conditions
- Insomnia, Cognitive Dysfunction, Mild Cognitive Impairment, Sleep Initiation and Maintenance Disorders
- Trial name
- NCT05565833
- Testing
- SHUTi OASIS, Patient Education
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Virginia
Mild Cognitive Impairment, Randomized Controlled Trial
Effects of a Computerised Cognitive Stimulation Versus Stimulating Leisure Activities
The aim of the study is to evaluate, at the level of global cognition, cognitive neuroconstructs, memory, verbal fluency, ADLs, IADLs, symptoms of depression and anxiety, the effectiveness of a personalised and adapted…
- Conditions
- Mild Cognitive Impairment, Randomized Controlled Trial, Subjective Cognitive Impairment
- Trial name
- NCT06058611
- Testing
- Cognitive stimulation, Stimulating leisure activities
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Vascular Cognitive Impairment no Dementia
Mexidol® Efficacy and Safety in Treatment of VCIND in Older Adults
The primary objective of this study is to evaluate the efficacy of Mexidol® sequential parenteral and oral administration as part of comprehensive therapy in older adults with chronic brain ischemia and vascular cognitive…
- Trial name
- NCT07700615
- Testing
- Mexidol, Standard Therapy
- Where
- 4 sites in Russia
- Volunteers
- 120 people
- Sponsor
- Pharmasoft
Alzheimer's Disease
Utilization of Exergame Programs Among Elderly Residents in Rural Nursing Care Centers
Background: Cognitive impairment is prevalent among older adults and frequently misdiagnosed or diagnosed late, increasingly drawing attention as a significant health issue in aging populations.
- Trial name
- NCT06717971
- Testing
- Exergame-based multicomponent training program., Standard care
- Where
- China
- Volunteers
- 232 people
- Sponsor
- Aoyu Li
Dementia, Alzheimer Disease
Effectiveness of a 3-month Individual Reminiscence Therapy Program in Older Adults With Alzheimer's Disease
This research aims to evaluate the effectiveness of individual Reminiscence Therapy (RT) program, using a simple reminiscence format, to improve the overall cognitive function, mood, and quality of life (QoL) of older adults with…
- Conditions
- Dementia, Alzheimer Disease, Cognitive Impairment
- Trial name
- NCT06812442
- Testing
- Reminiscence therapy
- Where
- 4 sites in Portugal
- Volunteers
- 40 people
- Sponsor
- Rsocialform - Geriatria, Lda