Clinical trials: Older Adults With Mild Neurocognitive Disorders
Quality of Life, Aging
Effects of Functional Training by High Intensity Intervals in Older Adults With Mild Cognitive Impairment.
To analyze the effects of a high intensity interval functional training program (HIFT), in the cognitive and functional capacities of Colombian older adults with mild cognitive impairment.
- Trial name
- NCT04638322
- Testing
- HIFT Group
- Where
- Colombia
- Volunteers
- 52 people
- Sponsor
- University of Jaén
Mild Cognitive Impairment
A Scalable Model for Promoting Functioning and Well-Being Among Older Adults With Mild Cognitive Impairment Via Meaningful Social Interactions: Project SPEAK!
The goal of this study is to refine and test a strategy for engaging older adults with symptoms of SCD/MCI (subjective cognitive decline/mild cognitive impairment) as volunteers to help English language learners (ELLs) who live…
- Trial name
- NCT04717479
- Testing
- Intervention (videoconferencing)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Technology
Therapeutic Effectiveness of PARO Companion Robot for Elderly With Mild Cognitive Impairment/Dementia in Elderly Residential Setting: A Quasi-experimental Study
The main trial is a 2-group quasi-experimental trial of comparing the outcome indicators between joining and not joining the 10-week personal assistive robot (PARO) training program in residents with dementia or mild cognitive…
- Trial name
- NCT05404802
- Testing
- Experimental group intervention, Control group intervention
- Where
- 2 sites in Hong Kong
- Volunteers
- 37 people
- Sponsor
- The University of Hong Kong
Cognitive Dysfunction, Alzheimer Disease
Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older Adults
BACKGROUND Cognitive decline in older adults, especially those who develop Mild Cognitive Impairment and Alzheimer's Disease, currently has limited options of pharmacological treatments, with modest efficacy.
- Conditions
- Cognitive Dysfunction, Alzheimer Disease, Mild Cognitive Impairment, Cognitive Decline
- Trial name
- NCT06733714
- Testing
- Transcranial Alternating Current Stimulation, Digital Cognitive Training
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Alzheimer Disease, Mild Cognitive Impairment
Implementation of AIP Services for Older Adults With AD
This study will longitudinally follow a cohort of older adults to better understand how decisions about aging in place or transitioning to long-term care-and the implementation of those decisions-are influenced by age-related…
- Trial name
- PYL-AIP (NCT07361601)
- Where
- United States
- Sponsor
- Northwestern University
Mild Cognitive Impairment (MCI), Exercises
High-Amplitude Functional Exercises in Older Adults With Mild Cognitive Impairment
This study will investigate the effects of dual-task-based high-amplitude functional exercises on balance and functional mobility in older adults with mild cognitive impairment.
- Trial name
- NCT07762235
- Testing
- Dual-Task-Based High-Amplitude Functional Exercise Program, Traditional Balance and Mobility Exercise Group
- Volunteers
- 36 people
- Sponsor
- Istinye University
Mild Cognitive Impairment
Evaluation of a Digital Neurorehabilitation Program Using Exergames for Adults With Mild Cognitive Impairment
The goal of this clinical trial is to learn whether a semi-autonomous digital telerehabilitation program using therapeutic video games ("exergames") can help improve quality of life and functional independence in older adults…
- Trial name
- NCT07423260
- Testing
- Digital exergame-based neurorehabilitation program, Individual conventional physiotherapy
- Where
- Spain
- Volunteers
- 38 people
- Sponsor
- European University of Madrid
Mild Neurocognitive Disorder
Long Term Transcranial Pulse Stimulation (TPS) on Older Adults With Mild Neurocognitive Disorder (NCD)
Background: Dementia, now known as major neurocognitive disorder (NCD), is a great health burden in Hong Kong and worldwide. In principle, to achieve its optimal benefits, intervention for dementia should begin at the earliest…
- Trial name
- NCT05602467
- Testing
- Transcranial Pulse Stimulation (TPS), Treatment as usual (TAU)
- Where
- Hong Kong
- Volunteers
- 22 people
- Sponsor
- The University of Hong Kong
Mild Cognitive Impairment (MCI)
VR Hand Exercises: Impact on Cognition and Dexterity in MCI
This study aims to investigate the effects of virtual reality (VR)-based hand exercises on cognitive functions and hand skills in older adults with mild cognitive impairment (MCI).
- Trial name
- NCT07005271
- Testing
- virtual reality, Conventional treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Istinye University
Mild Cognitive Impairment, Older Adults
Virtual Reality Cognitive Training for Older Adults With Mild Cognitive Impairment
This study aims to (1) develop and assess the feasibility of a fi-VRCT program based on IADL for older adults with MCI, (2) implement and evaluate the effectiveness of the fi-VRCT program based on IADL in older adults with MCI…
- Trial name
- NCT06392412
- Testing
- fi-VR Cognitive Training, Traditional Cognitive Training
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Da-Yeh University
Cognitive Impairment
Cognitive Stimulation and Strength Training in Older Adults With Cognitive Impairment
This program focuses on integrating cognitive exercises and strength training for older adults experiencing mild cognitive impairment (MCI).
- Trial name
- NCT06666088
- Testing
- Cognitive stimulation and Strength training
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- University of Jaén
Mild Cognitive Impairment, Gait
Association of Perceived Occupational Performance and Satisfaction, Balance, Gait, and Fear of Falling in Older Adult With Mild Cognitive Impairment
This study was designed to investigate the occupational performance and balance, gait, and fear of falling in older adults with MCI.
- Conditions
- Mild Cognitive Impairment, Gait, Balance, Occupational Problems
- Trial name
- NCT06513325
- Testing
- Canadian Occupational Performance Measure
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gulhane School of Medicine
MCI
Motor-cognitive Interventions Are Effective in Improving Cognitive Function in Older Adults With Mild Cognitive impairment--a Chinese Sample
Mild cognitive impairment (MCI) is a syndrome that occurs in the preclinical stage of Alzheimer, and early intervention can be effective in preventing Alzheimer, but further research is needed on intervention methods.
- Trial name
- NCT05764421
- Testing
- motor-cognitive intervention
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Jinxuan Cheng
Mild Cognitive Impairment, Mild Dementia
Validation of the German Version of the Amsterdam Instrumental Activities of Daily Living Questionnaire®
Pretest and validation of the German version of the Amsterdam instrumental activities of daily living questionaire short in elderly people with normal cognition, mild cognitive impairment (MCI) or mild dementia in the German…
- Trial name
- NCT04012398
- Testing
- Amsterdam IADL Questionnaire short, German version
- Where
- Switzerland
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Zurich University of Applied Sciences
Cognitive Impairment, Aging
Influence of Overground Walking on Biomarkers, Cognitive Function, and Quality of Life in Elderly With Mild Cognitive Impairment
The purpose of this research is to investigate the impact of overground walking as a part of a rehabilitation program on the increase in Brain-derived neurotrophic factor (BDNF) levels, decrease in IL-6 levels, decrease in hs-CRP…
- Trial name
- NCT06029920
- Testing
- Overground Walking
- Where
- Indonesia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Alzheimer Disease, Mild Cognitive Impairment
A Scalable Nutrition Adherence Intervention
Objective 1: To scale-up the nutrition adherence intervention for testing in racially diverse rural communities in North Florida. The investigators hypothesize that: 1.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Adherence
- Trial name
- NCT06121986
- Testing
- Improving Cognitive Aging through Nutrition (ICAN) Adherence Program, Improving Cognitive Aging through Nutrition, Mediterranean diet
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Florida State University
Mild Cognitive Impairment (MCI), Memory Disorders, Age Related
Music for the Mind Study
The goal of this pilot clinical trial is to learn if older adults with mild cognitive impairment (MCI) find two music programs equally acceptable.
- Conditions
- Mild Cognitive Impairment (MCI), Memory Disorders, Age Related, Memory Decline
- Trial name
- M4M (NCT06866327)
- Testing
- Piano lessons, Music Lessons
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Rochester
Alzheimer Disease, Late Onset, Mild Cognitive Impairment
Time-in-bed Restriction in Older Adults With Sleep Difficulties With and Without Risk for Alzheimer's Disease
Dementia caused by Alzheimer's disease affects approximately 5.6 million adults over age 65, with costs expected to rise from $307 billion to $1.5 trillion over the next 30 years.
- Conditions
- Alzheimer Disease, Late Onset, Mild Cognitive Impairment, Sleep, Cognitive Change
- Trial name
- ALPS (NCT05138848)
- Testing
- Time in Bed Restriction, Sleep Schedule
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cognitive Dysfunction, Mild Cognitive Impairment
Cognitive and Physical Home-rehabilitation by Information and Communications Technology. Games for Older Adults Active Life (GOAL)
Aging is often associated with pathological pathway such as in Mild Cognitive Impairment (MCI), and that pathway may be associated to a high risk of dementia.
- Conditions
- Cognitive Dysfunction, Mild Cognitive Impairment, Vascular Cognitive Impairment
- Trial name
- GOAL (NCT03383549)
- Testing
- Tele-rehabilitation
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Older Adults With Mild Neurocognitive Disorders, Older Adults With Non-communicable Diseases
Application of VR-based Working Memory Screening Test
We propose to validate an interactive, immersive spatial memory test from the laboratory test. This VR-based working memory test (VRWMT) is a first-person, self-pacing game embedded within a virtual reality environment, the…
- Conditions
- Older Adults With Mild Neurocognitive Disorders, Older Adults With Non-communicable Diseases, Healthy Age-matched Older Adults
- Trial name
- VR (NCT04600726)
- Testing
- no intervention
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University