Clinical trials: Older Men
HIV, PrEP
Self-Consent for PrEP Perspectives
This study involves a one-time, web-based quantitative structured self-complete ("web-based") survey for all subjects and a qualitative semi-structured ("qualitative") interview for a selected sub-sample of subjects to evaluate…
- Trial name
- NCT02801760
- Where
- 11 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Bone Strength, Neuromuscular Function
The Influence of High Impact Exercise on Musculoskeletal Health in Older Men
Osteoporotic fractures are an extremely common and serious public health issue which contribute substantially to pain, impaired mobility and morbidity in the elderly.
- Trial name
- Hiphop (NCT02007460)
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Human Immunodeficiency Virus, Cardiometabolic Risk
The Happy Older Latinos Are Active (HOLA) Health Promotion Study in HIV-Infected Latino Men
The purpose of this study is to examine the feasibility of an intervention to prevent chronic diseases like diabetes, high blood pressure, and obesity in midlife and older Latino adults living with HIV.
- Trial name
- HOLAHIV (NCT03839212)
- Testing
- HOLA Component 1, HOLA Component 2, HOLA Component 3
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Exercise Training
Plyometric Exercise to Improve Rapid Force Production in Older Men
Rapid force production declines as a consequence of ageing. Given the functional relevance of rapid force production, exercise interventions in older adults should aim at improving the capacity to produce force rapidly.
- Trial name
- NCT03645772
- Testing
- Exercise intervention
- Where
- Belgium
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Aging
Fiber and Calcium Absorption in Older Men
Osteoporotic fractures are a major but underrecognized problem in men. There is growing evidence that low dietary fiber intake is a modifiable risk factor for age-related bone loss in men.
- Trial name
- NCT06519877
- Testing
- Soluble corn fiber
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Hypogonadism
Does Testosterone Improve Function in Hypogonadal Older Men
This is a randomized controlled trial of testosterone replacement therapy in hypogonadal men age > 60 years. The goal is to assess the safety and efficacy of TRT in men age > 60 years.
- Trial name
- NCT00304213
- Testing
- Testosterone
- Where
- United States
- Sponsor
- North Florida Foundation for Research and Education
Hypertension, Erectile Dysfunction
EECP for Erectile Dysfunction in Elderly Hypertensive Patients
Hypertension and erectile dysfunction are common health problems in older men and may share vascular dysfunction as an underlying mechanism.
- Trial name
- NCT07831551
- Testing
- Enhanced External Counterpulsation
- Where
- 2 sites in China
- Volunteers
- 106 people
- Sponsor
- Qilu Hospital of Shandong University
Aging
Project SIRT6 Activator
The global ageing population is increasingly affected by age-related diseases, which are challenging healthcare systems. Current treatments often extend lifespan without improving healthspan.
- Trial name
- NCT07500649
- Testing
- Fucoidan
- Where
- 2 sites in Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Chronic Disease of Cardiovascular System, Multiple Chronic Conditions
MOCHA Moving Forward: a CBPR Investigation of Chronic Disease Prevention in Older, Low-income African-American Men
The overall goal of the research is to discover how to reduce chronic disease health disparities among older (ages 35-70) low-income African-American men more effectively.
- Conditions
- Chronic Disease of Cardiovascular System, Multiple Chronic Conditions, Chronic Disease
- Trial name
- NCT03745703
- Testing
- MOCHA
- Where
- 2 sites in United States
- Volunteers
- 261 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Older Adults, Reduced Physical Activity
Step-reduction in Older Men and Women
This study investigates the effects of two weeks of reduced daily ambulation and a subsequent return to normal physical activity on metabolic health of older adults.
- Trial name
- CDA-SR (NCT03039556)
- Testing
- Normal Daily Steps, Step-Reduction, Return to Normal Daily Steps
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- McMaster University
Endothelial Dysfunction
A Clinical Trial for People HIV+ Age > 50 at Risk for Heart Disease
This research study is to see whether blood vessel function, an early sign of heart disease, improves in HIV-infected men and women who take telmisartan for 12 weeks.
- Trial name
- NCT01578772
- Testing
- Telmisartan
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of California, Los Angeles
Physical Inactivity, Mobility Limitation
The Men on the Move Study
The Men on the Move Study is a randomized, controlled, feasibility study designed to address the health problem of physical inactivity in older men.
- Conditions
- Physical Inactivity, Mobility Limitation, Older Men
- Trial name
- NCT02527655
- Testing
- Choice-Based Physical Activity and Active Transportation
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Healthy
Isokinetic Testing Protocol in Elderly and Young Men
An age-related decrease in muscular strength may have a detrimental effect on muscle fatigue and recovery. To date, only one study has determined the effect of varied rest intervals (RI) between exercise sets in active younger…
- Trial name
- NCT00673998
- Testing
- Isokinetic Dynamometer (Biodex system III)
- Where
- Brazil
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Aging
The Effect of Velocity Training in Functionally Limited Elderly
We are exploring a unique weight-training program for men and women 65 years or older that emphasizes high speed training. We believe that the speed at which muscles move may be more important to the performance of functional…
- Trial name
- NCT01211496
- Testing
- High-speed power training, Slow-speed strength training
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Cognitive Function, Mood
A Study by ChromaDex to Assess the Effects of TRU NIAGEN on Cognitive Function, Mood and Sleep in Older Adults
The sponsor of this study is ChromaDex, Inc. This is a double-blind, randomized, crossover study to investigate the effects of 300 mg/d and 1000 mg/d TRU NIAGEN (nicotinamide riboside) compared to a placebo control on cognitive…
- Conditions
- Cognitive Function, Mood, Sleep
- Trial name
- NCT03562468
- Testing
- 300 mg/day of TRU NIAGEN (nicotinamide riboside), 1000 mg/day of TRU NIAGEN (nicotinamide riboside)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ChromaDex, Inc.
Hypertension, Medication Adherence
Medication Adherence Program
Randomized controlled trial testing the efficacy of the Supporting Tailored Adaptive change and Reinforcement for Medication Adherence Program (STAR-MAP), a health coaching approach that aims to improve antihypertensive…
- Conditions
- Hypertension, Medication Adherence, Behavior and Behavior Mechanisms
- Trial name
- MAP (NCT05183763)
- Testing
- STAR-MAP health coaching, Medication reminder tools
- Where
- 5 sites in United States
- Volunteers
- 402 people
- Sponsor
- Tulane University
Suicide, Attempted
Cognitive Therapy for Suicidal Older Men
The primary aim of the proposed study is to compare the efficacy of cognitive therapy (CT) with the efficacy of an enhanced usual care (EUC) intervention for reducing the rate of suicide ideation (SI) and the severity of…
- Trial name
- NCT01535482
- Testing
- Cognitive Therapy, Enhanced Usual Care
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Pennsylvania
Tolerance, Safety Issues
Buck Institute Ketone Ester RCT
This study is to investigate the tolerability and safety of a ketone promoting ingredient, called a ketone ester (KE), in healthy older adults.
- Conditions
- Tolerance, Safety Issues, Aging
- Trial name
- BIKE (NCT05585762)
- Testing
- Ketone ester
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Buck Institute for Research on Aging
Healthy
Safety and Tolerability of MK0773 in Healthy Older Men (0773-004)
This study will assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of MK0773 in healthy older men.
- Trial name
- NCT01017458
- Testing
- MK0773, Comparator: testosterone enanthate
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Suicide, Attempted
Cognitive Therapy for Suicidal Older Men in Primary Care Settings
This study will assess the effectiveness of cognitive therapy in reducing the incidence of suicide ideation and behavior in older men in a primary care setting.
- Trial name
- NCT00149773
- Testing
- Cognitive Therapy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Pennsylvania