Clinical trials: Oligospermia
Sperm Count, Low, Hormone Disturbance
Semen Parameters and COVID-19 in Infertile Men
Coronavirus Disease-19 (COVID-19) is a global pandemics which affects many organs and systems with a range of morbidities and high mortality rates.
- Conditions
- Sperm Count, Low, Hormone Disturbance, Covid19
- Trial name
- NCT04643522
- Testing
- Clinical assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Ankara City Hospital Bilkent
Azoospermia, Oligozoospermia
Autologous Adipose-Derived Adult Stromal Vascular Cell Administration for Male Patients With Infertility
Severe Oligospermia (oligozoospermia) refer to semen with a low concentration of sperm and is a common finding in male infertility.
- Trial name
- NCT03762967
- Testing
- Lipoaspiration and SVF introduction., Standard therapy.
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- State-Financed Health Facility "Samara Regional Medical Center Dinasty"
Sperm Count, Low
Impact of Immunotherapy on the Sperm Count of Patients With Cancer
Cancer is a public health problem. In recent years, oncology has been revolutionized with the advent of new treatments for different tumor models, mainly immunotherapy directed against cell cycle control points.
- Trial name
- NCT04554030
- Testing
- Evaluate sperm count before and after immunotherapy
- Where
- Argentina
- Volunteers
- 30 people
- Sponsor
- Hospital Italiano de Buenos Aires
Oligospermia
Seminal Fluid's Changes Over 20 Years
This is a cohort study including all the first seminal exams performed at the Fertility Center, Humanitas Research Hospital (Rozzano, Milan) between January 1998 and December 2018.
- Trial name
- NCT04349345
- Testing
- sperm count
- Volunteers
- 24,395 people
- Sponsor
- Istituto Clinico Humanitas
Cylinical Embryo, Oligospermia
Sperm Pathology Samples and Morphokinetics
The embryo kinetics may be a new prognostic factor for choosing the embryos with the highest implantation potential. In order to identify the factors that may affect the rate of embryo cleavage, there are many studies about…
- Trial name
- NCT02155179
- Where
- 2 sites in Spain
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Sperm Count, Low, Reproductive Sterility
A Retrospective Study on the Effect of Male Progressive Sperm Count After Semen Pretreatment on ICSI Fertilization Outcome
The investigators plan to retrospectively analyze clinical data from 14,189 fresh ICSI cycles in Reproductive and Genetic Hospital of CITIC-Xiangya from January 2016 to December 2017.The investigators will regard total…
- Trial name
- NCT03594201
- Testing
- semen pretreatment
- Where
- China
- Volunteers
- 12,215 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Infertility, Male, Oligozoospermia
The Role of Artery-Preserving Varicocelectomy in Subfertile Men With Severe Oligozoospermia.
A male factor is responsible for almost half the cases of subfertility. Varicocele is a major cause of impaired spermatogenesis and potentially a correctable cause.
- Conditions
- Infertility, Male, Oligozoospermia, Varicocelectomy
- Trial name
- NCT03344588
- Testing
- artery preserving varicocelectomy, artery ligation varicocelectomy
- Where
- Egypt
- Volunteers
- 330 people
- Sponsor
- Mansoura University
Azoospermia, Nonobstructive, Oligozoospermia
Effect of Letrozole on Seminal Parameters in Men With Non Obstructive Azoospermia and Severe Oligozoospermia.
The investigators hope to learn if Letrozole is effective and safe in improving severe male infertility by increasing testosterone, decreasing oestradiol and stimulating sperm production thereby improving sperm motility…
- Trial name
- NCT02900105
- Testing
- Letrozole
- Where
- Singapore
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Oligospermia, Teratospermia
Ramipril for the Treatment of Oligospermia
This is a randomized controlled trial to evaluate the effect of ramipril in stimulating and promoting sperm production in men with low sperm count.
- Conditions
- Oligospermia, Teratospermia, Asthenozoospermia, Male Infertility
- Trial name
- NCT01856361
- Testing
- Ramipril
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Oligoasthenoteratozoospermia
Severe Male Factor Infertility Management
This study is the first to evaluate the effect of oral supplementation with antioxidants combined with lifestyle modification for severe male factor partner of couples undergoing ICSI.
- Trial name
- OAT (NCT02752555)
- Testing
- Antioxidant (l-cratinine) + modifiable lifestyle factors
- Where
- 3 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Obesity, Oligospermia
Aromatase Inhibitors in the Treatment of Male Infertility
Obesity is associated with an increase in blood levels of estrogen. Estrogen or "female hormone" is believed to have a negative effect on sperm production.
- Trial name
- NCT00440180
- Testing
- Anastrozole
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Utah
Oligozoospermia, Azoospermia
The Effect of Low Electrical Current on Testicular Spermatocyte Count
Oligozoospermia, refers to a low concentration of sperm. A low sperm count or poor sperm quality is the cause of infertility in about 20% of couples with fertility problems, and a contributory factor in a further 25% of couples.
- Trial name
- NCT02617173
- Testing
- Micro 400 Matrix Therapy Products
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Sheba Medical Center
Oligospermia, Azoospermia
Clinical Research on Effectiveness and Safety of Treatment of Severe Oligospermia or Azoospermia With uFSH
The purpose of this study is to determine whether uFSH is effective and safe in the treatment of male patients with severe oligospermia or azoospermia.
- Trial name
- NCT02307994
- Testing
- 75IU uFSH
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Livzon Pharmaceutical Group Inc.
Insulin Resistance, Oligospermia
Insulin Resistance in Idiopathic Oligospermia and Azoospermia
Insulin resistance in men can be the underlying major factor in reproductive abnormalities ( chronic hypospermatogenesis ) as well as metabolic abnormalities similar to polycystic ovarian syndrome ( PCOS ) in women.
- Conditions
- Insulin Resistance, Oligospermia, Azoospermia
- Trial name
- NCT01509482
- Testing
- blood samples
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Egyptian IVF-ET Center
Oligospermia
A Clinical Trial to Study the Safety and Efficacy of Chandrakanthi Choornam in Patients With Low Sperm Count
This is an Open clinical trial to study the safety and efficacy of Chandrakanthi Choornam in 40 patients with Oligospermia. Chandrakanthi choornam is a formulation consisting of 25 ingredients.
- Trial name
- NCT02234206
- Testing
- Chandrakanthi Choornam (CKC)
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Tamil Nadu Dr.M.G.R.Medical University
Male Subfertility, Oligospermia
7 NUTS Study. Diet Modification and Male Fertility.
Setting. Outpatient fertility clinic. Aim. Investigate if a modification in nutritional habits may improve in the short term the qualities of human sperm, testing two hypothesis: i) that adding to the diet a natural whole food…
- Conditions
- Male Subfertility, Oligospermia, Asthenospermia, Teratospermia
- Trial name
- NCT02063256
- Testing
- 7 nuts a day, Diet modification
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Oligospermia
The Effect and Safety of Lisinopril in Non-hypertensive Men With Infertility From Low Sperm Count
This study was conceived in order to explain what the investigators previously observed suggesting that lisinopril, a drug normally used to treat patients with high blood pressure and heart failure, may be effective in treating…
- Trial name
- NCT01409837
- Testing
- Lisinopril
- Where
- Nigeria
- Volunteers
- 33 people
- Sponsor
- University Of Nigeria Teaching Hospital
Oligospermia
Identification and Characterization of the Methylation Abnormalities on Whole Genome Among Infertile Men
This study will analyse the sperm global methylation status of 62 infertile men before assisted reproductive techniques. Some of these patients (20%) present hypomethylation of H19 locus.
- Trial name
- METHYLHOMME (NCT01239186)
- Testing
- methylation analyses on spermatozoa from infertile men
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Oligospermia
Supplement Intake in Infertile Men;the Effect on Sperm Parameters,Fertilization Rate and Embryo Quality
The vitamin,minerals and amino acid supplementation for 3 months will improve the semen parameters,fertilization rate and embryo quality in subfertile men undergoing IVF treatment
- Trial name
- NCT01520584
- Testing
- Vitamale
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Oligospermia, Azoospermia
Genetic Studies Spermatogenic Failure
The proposed study is designed to test the following hypotheses: 1. Mouse autosomal or X-linked genes which are exclusively expressed in mouse spermatogonia are also spermatogonia-specific in human. 2.
- Conditions
- Oligospermia, Azoospermia, Male Infertility
- Trial name
- NCT00548977
- Testing
- Drawing blood to study genetic polymorphism
- Where
- Taiwan
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital