Clinical trials: Omega-3 Fatty Acids
Heart Disease
Heart & Health Study
We hope to learn more about why certain people have higher levels of the 5-LO protein and whether taking fish oil supplements gives such individuals greater protection than others against cardiovascular disease.
- Trial name
- NCT00536185
- Testing
- Fish Oil
- Where
- 3 sites in United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Inflammation
Fish Oil (Omega 3), Immune Function, and Mood
This study is designed to examine the effects of fish oil on immune function and mood.
- Trial name
- NCT00385723
- Testing
- Omega 3 (Fish Oil) Supplementation
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Inflammation, Malnutrition
Effects of Camelina Sativa Oil in Free-living Older Adults
The present study aims at evaluating the anti-inflammatory effects of a novel food in older adult volunteers. Briefly, this randomized, double-blind and placebo-controlled study is performed on 91 apparently healthy older adults…
- Conditions
- Inflammation, Malnutrition, Hyperglycemia, Dyslipidemias
- Trial name
- NCT04965948
- Testing
- Novel food snack
- Where
- Italy
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Omega-3 Deficiency, DHA and EPA Blood Levels
A Clinical Trial to Evaluate the Effects of an Omega-3-containing Supplement on DHA and EPA Levels in the Blood
This is a 12-week, hybrid, single-arm clinical trial designed to evaluate the effects of an omega-3-containing supplement (Omega Active) on DHA and EPA levels in the blood.
- Conditions
- Omega-3 Deficiency, DHA and EPA Blood Levels, Cardiovascular Health, Cognitive Health
- Trial name
- NCT07753174
- Testing
- Omega Active Supplement
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Revive Active
Healthy
To Evaluate the Effects of Omega 3 Fatty Acids in the Context of Cancer Prevention
Previous studies have demonstrated, in an in vitro micro-tumour model (the spheroid) and in a mouse model, that long-chain omega-3 fatty acids, in particular docosahexaenoic acid (DHA), can inhibit tumour development.
- Trial name
- NCT05427604
- Testing
- Olive oil, DHA oil
- Where
- Belgium
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Maternal Obesity, Obesity
The Developmental Origins of Obesity
Pregestational obesity (PGO, BMI ≥30) is a significant independent risk factor for the development of obesity in childhood and adolescence.
- Trial name
- OMEGA-Stem (NCT06981676)
- Testing
- DHA and EPA
- Where
- Chile
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Sarcopenia
A Comparison of the Effects of Krill Oil and Fish Oil Supplementation on Muscle Function in Older Adults
The aim of the study is to compare the effects of Krill Oil and Fish Oil supplementation on muscle function in older adults. The secondary aim is to investigate the mechanisms underlying the beneficial effects previously observed.
- Trial name
- NCT05869526
- Testing
- Fish oil, Kril oil, Vegetable oil
- Where
- United Kingdom
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Malnourishment
Cognitive Effects of Omega-3 Supplements in Children With Mild to Moderate Malnutrition
Adequate nutrition is one of the critical biological processes to learning and cognitive development of children. And is understandable that malnourishment affect these processes.
- Trial name
- NCT01199120
- Testing
- Omega 3
- Where
- Mexico
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Ciudad Juarez
Cardiovascular Risk Factor and Kidney Related Biomarkers
Omega-3 and Cardiovascular Risk Factors and Kidney Related Biomarkers
In this study, 99 overweight or obese women that referred to the Clinic Nutrition to lose weight were randomly divided into three groups according to body mass index (BMI) by random-number table (figure1).
- Trial name
- NCT03197220
- Testing
- fish, walnut, fish-walnut
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Insulin Resistance
Effects of Omega-3 Fatty Acid Supplementation and Physical Training on Metabolic Health
The degree of insulin resistance in an individual can be monitored by several means including blood concentrations of insulin, triglycerides, HDL-C, and eventually glucose.
- Trial name
- EXC (NCT06533891)
- Testing
- DPA enriched n-3, n-3 control
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Arizona
Obesity
Omega-3 Fatty Acid Supplementation and Fractional Iron Absorption in Obese South African Women
In South Africa the prevalence of obesity in women of reproductive age is high; these women also have a high risk for iron deficiency (ID).
- Trial name
- NCT05220735
- Testing
- Omega-3 long chain polyunsaturated fatty acids (n-3 LCPUFA)
- Where
- South Africa
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Overweight
Fish Oil and Inflammation in Overweight Subjects
The aim of this study is to investigate the effects of acute and short-term intervention with fish oil on inflammatory markers in overweight subjects.
- Trial name
- ADIPOMEGA (NCT00885053)
- Testing
- fish oil, olive oil
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Coronary Artery Disease
Intravenous Fish Oil in Critically Ill Cardiac Patients
A large body of evidence has accumulated showing that n-3 PUFAs exert extensive cardiac effects. The development of commercial solutions of FO opens perspectives for therapeutic applications in patients with acute cardiac…
- Trial name
- FO-cardiac (NCT00516178)
- Testing
- Fish oil emulsion, Saline
- Where
- 2 sites in Switzerland
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Weight Gain, Healthy Subjects
Dietary Essential Fatty Acid Regulation of Omega-3 HUFA Metabolism; Satiety and Body Composition
Background: Rates of obesity have increased dramatically in recent decades, and researchers are investigating how changes in diets and physical activity have contributed to this increase.
- Conditions
- Weight Gain, Healthy Subjects, Obesity, Women
- Trial name
- NCT01251887
- Testing
- Linoleic Acid, Docosahexaenoic Acid, Eicosapentaenoic Acid
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Joint Function Disorder
Efficacy of a Dietary Ingredient Combination With Omega-3 for Joint Function
Randomized, controlled, double-blind intervention study of four parallel branches depending on the product consumed, to analyze the efficacy of an Omega-3 based product on the mobility and functionality of the evaluated joint.
- Trial name
- 7DHA (NCT05279573)
- Testing
- Omega-3 and/or botanical ingredient, Control product consumption
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Type 2 Diabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Effects of Different Fish Oil Types on Type 2 Diabetes Risk Factors in High-Risk Adults
The purpose of this clinical trial is to find out whether one type of fish oil works better than another at improving metabolic health in people who are at high risk of developing type 2 diabetes.
- Conditions
- Type 2 Diabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Prediabetes / Type 2 Diabetes, Obesity & Overweight
- Trial name
- END-T2D (NCT07575438)
- Testing
- Fish Oil, Corn oil control
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- May Faraj, PDt, PhD
Nutrition, Absorption, Metabolism and Excretion in Healthy Volunteers
Bioavailability of Omega-3 Fatty Acids From Fish Oil Supplements
This study is investigating whether a new type of fish oil supplement, in the form of soft chews, leads to better absorption of omega-3s in the body compared to traditional fish oil capsules.
- Conditions
- Nutrition, Absorption, Metabolism and Excretion in Healthy Volunteers, Fish Oils, Omega 3 Fatty Acids
- Trial name
- Ocean's O3 (NCT06665464)
- Testing
- Fish oil supplement 1, Fish oil supplement 2
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Wageningen University and Research
Cytokine Storm, Cytokines
The Effect of Omega-3 on Selected Cytokines Involved in Cytokine Storm
The trial was designed to assess the effect of daily dose of 300 mg omega-3 supplements for 2 months on the selected interleukins levels in uninfected people with Covid-19.
- Trial name
- NCT04483271
- Testing
- 300 mg of omega3-FA
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Applied Science Private University
Cardiovascular Diseases, Mood Disorders
Evaluating the Effects of Omega-3 Fatty Acids on Heart Disease and Behavior
Omega-3 fatty acids are a certain kind of fish fat that has recently been shown to have health benefits. This study will examine the effectiveness of fish oil supplementation for reducing the early signs of heart disease risk and…
- Conditions
- Cardiovascular Diseases, Mood Disorders, Inflammation
- Trial name
- NCT00663871
- Testing
- Fish Oil
- Where
- United States
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pregnancy
Therapeutic Omegas for Triglyceride Suppression
This study plans to learn more about how an omega-3 fatty acid supplement effects triglyceride levels in pregnancy. Triglycerides are a type of fat found in your blood.
- Trial name
- TOTS (NCT04349475)
- Testing
- Intervention Omega 3 Supplementation
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver