Clinical trials: Oncologic
Anxiety, Skin Neoplasms
Patient-Controlled Ambient Light to Reduce Pre-Visit Anxiety in Dermatology Patients
Many patients feel anxious while waiting to see a dermatologist, especially in clinics that diagnose and treat skin cancer. The purpose of this study was to learn whether spending 10 minutes before the visit in an exam room lit…
- Trial name
- NCT07896122
- Testing
- Patient-controlled ambient light (Serene Sphere)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Stanford University
Prostatic Neoplasm
Active Surveillance or Radical Treatment for Newly Diagnosed Patients With a Localized, Low Risk, Prostate Cancer START
The purpose of the START project is to evaluate the acceptability, the safety and the cost-effectiveness of a population based program of active surveillance for patients newly diagnosed with a localized, low risk, prostate…
- Trial name
- START (NCT03348722)
- Testing
- Active surveillance, Radical prostatectomy, Radiotherapy
- Where
- Italy
- Volunteers
- 850 people
- Sponsor
- Rete Oncologica Piemonte, Valle d'Aosta
Breast Cancer
Virtual RealiTy and mUsic in the Oncology SEtting - Phase 1
The VRtuose (Virtual RealiTy and mUsic in the Oncology Setting) project aims to evaluate the feasibility of implementing in day patient chemotherapy units a distraction strategy combining virtual reality (VR) and music which fits…
- Trial name
- VRtuose1 (NCT06305117)
- Testing
- Distraction strategy
- Where
- France
- Volunteers
- 60 people
- Sponsor
- International Agency for Research on Cancer
Oncology, Prostate Cancer
A Study of [18]F-PSMA-1007 in Patients With Known or Suspected Metastatic Prostate Cancer
A [18]F-PSMA-1007 PET/CT or PET/MRI scan are nuclear medicine tests used to create pictures of the whole body that may show where cells that express Prostate-Specific Membrane Antigen (PSMA) are found.
- Trial name
- NCT05712174
- Testing
- [18]F-PSMA-1007
- Where
- Canada
- Volunteers
- 176 people
- Sponsor
- AHS Cancer Control Alberta
Oncology [See Also, Affected System], Hematological Disease
Assessing the Effect of Contact Isolation on Nosocomial Colonization With ESBL-EC in German Hematology/Oncology Wards
This study aims to evaluate the impact of contact isolation on the rate of hospital-acquired transmissions of ESBL-producing Escherichia coli (ESBL-EC) and the rate of colonization and infection.
- Conditions
- Oncology [See Also, Affected System], Hematological Disease, Infection Due to ESBL Escherichia Coli
- Trial name
- CONTAIN (NCT02456818)
- Volunteers
- 2,264 people
- Sponsor
- University of Cologne
Wound Complication, Surgical Site Infection (SSI)
Prophylactic Subcutaneous Drainage After Gynecologic Oncology Midline Laparotomy
The goal of this clinical trial is to learn whether placing a small drain under the skin can help prevent wound problems after gynecologic oncology surgery in adult women with a thick layer of tissue under the skin.
- Conditions
- Wound Complication, Surgical Site Infection (SSI), Gynecologic Cancers
- Trial name
- SCDRAIN-GO (NCT07735962)
- Testing
- Prophylactic subcutaneous closed-suction drainage, Standard closure without subcutaneous drainage
- Where
- Turkey (Türkiye)
- Volunteers
- 334 people
- Sponsor
- Mahmut Yassa
Metastatic Colorectal Cancer
PRIME: Panitumumab Randomized Trial In Combination With Chemotherapy for Metastatic Colorectal Cancer to Determine Efficacy
The purpose of this study is to determine the treatment effect of panitumumab in combination with FOLFOX compared to FOLFOX alone as first line therapy for metastatic colorectal cancer
- Trial name
- NCT00364013
- Testing
- Panitumumab, FOLFOX regimen
- Volunteers
- 1,183 people
- Sponsor
- Amgen
Oncology, Bone Loss
Evaluating Radiomorphometric Indices and Fractal Dimension of the Pediatric Oncology Patients on Panoramic Images
This study evaluated pediatric oncology patients in terms of quality of bone and determine any relation between bone quality and radiotherapy/chemotherapy.
- Trial name
- NCT04213482
- Testing
- Panoramic Radiography
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nuh Naci Yazgan University
Anemia
Transfusion Requirements in Critically Ill Oncologic Patient
Blood transfusion in critical ill patients has been associated to several complications and worse outcome. Particularly in oncologic patients, red blood cell transfusion has been investigated as a factor of worse outcome and…
- Trial name
- TRICCOP (NCT01648946)
- Testing
- Red blood cell transfusion
- Where
- Brazil
- Volunteers
- 300 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Breast Cancer, Cancer of the Breast
Prehabilitation to Revolutionize Oncology: Telehealth Exercise for Cognitive Triumphs (The PROTECT Trial)
The investigators propose to deliver a pilot randomized controlled trial to 40 women newly diagnosed with breast cancer and scheduled to undergo chemotherapy.
- Trial name
- NCT05716542
- Testing
- Physical Activity Intervention
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Washington University School of Medicine
Cancer
Outcomes of Oncology Therapy in the Elderly: Trajectory of Functional Decline and Correlates of Change
The proposed project will document the degree of function decline, assess the relationship between function and cancer- related symptoms and evaluate relationships between function and quality of life.
- Trial name
- NCT01006902
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Vermont
Degradation of Top2b and Top2a in Human by Dexrazoxane, Time Course and Degradation of Top2b in Human by Dexrazoxane
Prevention of Heart Failure Induced by Doxorubicin With Early Administration of Dexrazoxane
The purpose of this research study is to determine whether early administration of Dexrazoxane prevents Doxorubicin induced cardiotoxicity.
- Conditions
- Degradation of Top2b and Top2a in Human by Dexrazoxane, Time Course and Degradation of Top2b in Human by Dexrazoxane, Effects of Dexrazoxane on Healthy Human
- Trial name
- PHOENIX1 (NCT03930680)
- Testing
- Dexrazoxane
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Breast Cancer, Gynecologic Cancer
Exercise Oncology Clinic Pilot Feasibility Trial
The purpose of this pilot study is to test a supervised exercise program for adults with a history of breast or gynecologic cancer to see if it is safe, helpful, and easy to take part in.
- Trial name
- NCT07765927
- Testing
- Supervised, Personalized Exercise Program
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Jess S. Gorzelitz
HER2-positive Breast Cancer, HER2+ Breast Cancer
HER2HEART-US: Prevention of Cardiotoxicity in Breast Cancer Patients Receiving HER2-directed Therapy
Ten to 15% of patients with breast cancer are HER2 positive, with treatment focused on targeting the HER2 receptor. Although these treatments are generally well tolerated, they are associated with an increased risk of…
- Trial name
- NCT06844669
- Testing
- Carvedilol, Empagliflozin
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Washington University School of Medicine
Hepatocellular Carcinoma
Erlotinib in Combination With Docetaxel in Advanced Hepatocellular and Biliary Tract Carcinomas
An unmet medical need exists for the successful therapy of patients with advanced hepatocellular and biliary tract malignances, with few and short lived disease responses to chemotherapy for both advanced stage hepatic and…
- Trial name
- NCT00532441
- Testing
- Erlotinib, Docetaxel
- Where
- 12 sites in United States
- Volunteers
- 25 people
- Sponsor
- Gabi Chiorean, MD
Pediatric Cancer, Quality of Life
Symptom Screening Linked to Care Pathways
Most children with cancer survive because they are given intensive treatments, but unfortunately, these treatments are associated with distressing symptoms.
- Trial name
- NCT04614662
- Testing
- SPARK Symptom Screening Linked to Feedback to Providers
- Where
- 21 sites in United States, Canada
- Volunteers
- 445 people
- Sponsor
- The Hospital for Sick Children
Oncology, Medical Devices
Capillary-Venous Paired Data Collection
Capillary-venous paired data collection.
- Conditions
- Oncology, Medical Devices, Healthy Subjects
- Trial name
- CaVeP-DC (NCT05926362)
- Where
- 2 sites in United Kingdom
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Entia Ltd
Stage II Lung Cancer, Stage III Lung Cancer
A Web-based Program to Help Caregivers of Lung Patients Learn About Available Supportive Care Resources
Clinical trial that tests the feasibility of a web based caregiver support resource, along with caregiver navigation sessions for caregivers of patients with stage II-IV lung cancer.
- Conditions
- Stage II Lung Cancer, Stage III Lung Cancer, Stage IV Lung Cancer
- Trial name
- CONNECT (NCT06383988)
- Testing
- Support for Caregiver - Generic List, Support for Caregiver - Personalized List, Internet-Based Intervention - CONNECT
- Where
- 25 sites in United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Childhood Cancer
Effect of Nutrition Counseling and Physical Exercise Prescription on Body Composition and Nutritional Status of 5-18 Years Pediatric Cancer Patients on Treatment at Jimma Medical Center Pediatric Hematology and Oncology Unit(JMC-PHOU), Jimma, Ethiopia
Malnutrition and associated muscle wasting are common health problems among pediatric cancer patients. However, the role of dietary counseling and physical exercise prescription intervention on both nutritional status and muscle…
- Trial name
- JMC-PHOU (NCT07558486)
- Testing
- dietary counseling and physical exercise prescription
- Where
- Ethiopia
- Volunteers
- 104 people
- Sponsor
- Jimma University
Oncology, Chemotherapy-Induced Peripheral Neuropathy
8 Weeks vs 12 Weeks Physical Exercise Programmes in Colorectal Cancer Patients
Chemotherapy is a cornerstone in the treatment of colon cancer; however, its effects extend beyond malignant cells. Because chemotherapeutic agents target rapidly dividing cells, they can also damage healthy tissues, resulting in…
- Trial name
- NCT07307690
- Testing
- Exercise, Physical activity recommendations
- Volunteers
- 50 people
- Sponsor
- University of Salamanca
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