Clinical trials: Oncological Outcome
Endometrial Cancer
Uterine Manipulator in Endometrial Cancer Surgery: Pro MUCEI Study
The uterine manipulator is a device commonly used in minimally invasive hysterectomy surgery for endometrial cancer. However, without substantial evidence to support its use, surgeons are required to make decisions about its use…
- Trial name
- proMUCEI (NCT05242276)
- Testing
- USE OF UTERINE MANIPULATOR DURING THE HYSTERECTOMY
- Where
- Spain
- Volunteers
- 1,200 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Breast Cancer
Evaluation of a Physical Activity Program in Overweight Breast Cancer Patients
Patients diagnosed with breast cancer generally have a fairly well prognosis with estimated average survival rates of 73% and five year survival rates of 89% in developed countries.
- Trial name
- I-Move (NCT02424292)
- Testing
- Physical activity
- Where
- 4 sites in Netherlands
- Volunteers
- 141 people
- Sponsor
- University Medical Center Groningen
Carcinoma, Renal Cell, Pathology
Prognostic Significance of Preoperative Hemoglobin A1c (HbA1c) in Renal Cell Carcinoma
The effect of preoperative glycemic control measured by HbA1c on renal cell carcinoma (RCC) outcome remains controversial. Thus, the investigators aim to examine the association of preoperative glycemic control with oncologic…
- Conditions
- Carcinoma, Renal Cell, Pathology, Treatment Outcome, Hemoglobin A1c Protein, Human
- Trial name
- NCT02417194
- Where
- South Korea
- Volunteers
- 238 people
- Sponsor
- Seoul National University Hospital
Prostate Cancer, Metastatic Prostate Cancer
The Effect of a Structured Strength and Endurance Training Program on Quality of Life, Fitness, Blood Parameters and Survival in Prostate Cancer Patients
Prostate cancer is the second most common cancer among men. Many patients experience a significantly reduced quality of life due to either the cancer itself or the side effects of treatment.
- Conditions
- Prostate Cancer, Metastatic Prostate Cancer, Prostate Cancer (Post Prostatectomy), Prostate Cancer Patients Treated by Radiotherapy
- Trial name
- ZMoveMent-1 (NCT07126860)
- Testing
- Structured combined resistance and aerobic training, Standard of Care
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Uterine Cervical Neoplasms
Oncological Outcome After Completing or Abandoning (Radical) Hysterectomy in Patients With Cervical Cancer and Intraoperative Detection of LN Positivity
The ABRAX trial is multicentre retrospective cohort study. Included are patients with negative LN in clinical staging, in whom LN involvement is detected intraoperatively.
- Trial name
- ABRAX (NCT04037124)
- Testing
- Cervical procedure
- Where
- Czechia
- Volunteers
- 718 people
- Sponsor
- General University Hospital, Prague
Cancer, Rectum
Converted Laparoscopic Resection of Upper Rectal Carcinoma T1-4 N0-1 in Obese Patients.
Background: laparoscopic resection (LAR) is a safe approach and widely used for rectal cancer after neoadjuvant chemo-radiotherapy, but short term and oncological outcome for converted cases to open surgery (cLAR), may be…
- Trial name
- NCT04401787
- Testing
- Anterior resection for upper rectal cancer in obese
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Breast Cancer Female, Breast Cancer
Assessment of Oncological Safety, Quality of Life, and Environmental Impact of the Green Breast Surgery Protocol
Breast Cancer (BC) is the primary oncological diagnosis in women, with the annual incidence expected to exceed 3 million new cases by 2040 due to population growth and aging.
- Conditions
- Breast Cancer Female, Breast Cancer, Breast Neoplasms
- Trial name
- BuGs (NCT06624917)
- Testing
- Green Breast Surgery Protocol
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- University of Rome Tor Vergata
Safety, Availability
The Parietal Peritoneum as a Substitute Graft for Venous Reconstruction in HPB Surgery
To evaluate the safety and outcome of the parietal peritoneum for venous reconstruction HPB surgery. Although the parietal peritoneum had already been used and published for the reconstruction of the vena cava, however this one…
- Conditions
- Safety, Availability, Venous Patency, Oncological Benefits
- Trial name
- NCT02121886
- Testing
- venous reconstruction with the parietal peritoneum
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beaujon Hospital
Cervical Cancer
Surgical Staging in Cervical Cancer Prior to Chemoradiation
The aim of this study is to determine whether the modified therapy on the basis of operative staging and systematic, pelvine and paraaortal lymphadenectomy for patients with cervical cancer of the FIGO stages IIB-IV prior to…
- Trial name
- uterus11 (NCT01049100)
- Testing
- lymphadenectomy, Standard Staging
- Where
- 2 sites in Germany
- Volunteers
- 250 people
- Sponsor
- Charite University, Berlin, Germany
Distal Cholangiocarcinoma
Minimally Invasive Pancreatoduodenectomy for Distal Cholangiocarcinoma
Outcomes for minimally invasive and open pancreatoduodenectomy for distal cholangiocarcinoma have not been compared. This is an international multicenter propensity score matched cohort study including patients after MIPD or OPD…
- Trial name
- NCT05478889
- Testing
- Minimally invasive pancreatoduodenectomy
- Where
- Italy
- Volunteers
- 478 people, healthy volunteers welcome
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Oncologic Disorders
Disease Course in Oncological Patients During Inpatient Rehabilitation and After Three Months Follow-up
Constant improvements in the areas of diagnostics and treatment lead to an increase of patients surviving an oncological diagnosis ("cancer survivors") thus increasing the cost factor on both society and health care systems.
- Trial name
- NCT04842214
- Testing
- Oncological Rehabilitation
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- Klinik Valens
Breast Cancer
Single-dose Preoperative Partial Breast Irradiation in Low-risk Breast Cancer Patients
In this ABLATIVE-2 trial, low-risk breast cancer patients will be treated with MRI-guided single dose preoperative partial breast radiotherapy to assess the rate of pathologic complete response after an interval of six to twelve…
- Trial name
- ABLATIVE-2 (NCT05350722)
- Testing
- Single dose ablative radiotherapy
- Where
- 7 sites in Australia, Netherlands
- Volunteers
- 100 people
- Sponsor
- Amsterdam UMC, location VUmc
Patient Reported Outcome, Oncological Safety
Patient Report Outcome and Oncological Safety -Oncoplastic and Conventional BCS Cohort
Breast-conserving surgery (BCS) is the traditional surgical treatment for early-stage breast cancer patients. There are evidences indicating that oncoplastic BCS could improve cosmetic outcomes and/or quality of life, and has…
- Conditions
- Patient Reported Outcome, Oncological Safety, Breast-conserving Surgery, Breast Cancer Female
- Trial name
- NCT05054777
- Testing
- oncoplastic breast-conserving surgery, conventional breast-conserving surgery
- Volunteers
- 5,000 people
- Sponsor
- Shandong Cancer Hospital and Institute
Osteosarcoma, Pediatric
Oncological and Functional Outcomes in Lower Limb Osteosarcoma Pediatric Patient
Retrospective analysis of specific characteristics of complications and long-term oncological and function outcomes in lower-limb osteosarcoma pediatric patients.
- Conditions
- Osteosarcoma, Pediatric, Lower Limb Injury, Outcome
- Trial name
- NCT06162962
- Testing
- Retrospective analysis
- Where
- China
- Volunteers
- 345 people
- Sponsor
- Changye Zou
Database, Prostate Cancer
National Robotics-Assisted Radical Prostatectomy Database
In Australia, nearly 70 men are diagnosed with Prostate cancer every day. Prostate removal (Radical Prostatectomy) is the proven treatment option to control cancer spread.
- Conditions
- Database, Prostate Cancer, Robotic-assisted Radical Prostatectomy, Surgical Outcomes
- Trial name
- RASOR (NCT06279260)
- Where
- 8 sites in Australia
- Volunteers
- 10,000 people
- Sponsor
- Melbourne Health
Tongue Squamous Cell Carcinoma
Oncological Outcome of Contralateral Submental Artery Island Flap Versus Primary Closure in Tongue Squamous Cell Carcinoma
The purpose of this study is to compare the oncological and functional results of the contralateral submental flap with primary closure for reconstruction of tongue squamous cell carcinoma.
- Trial name
- NCT03440151
- Testing
- contralateral submental flap for tongue cancer defect, primary closure for tongue cancer defect
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University
Rectal Cancer
Short Running Head Obesity in Rectal Cancer Patients
There is a controversy regarding the effect of the two Body Mass Index (BMI) extremes on the oncological outcome of rectal cancer.
- Trial name
- NCT04759638
- Where
- Jordan
- Volunteers
- 294 people
- Sponsor
- King Hussein Cancer Center
Patient Related Outcome Measures, Supportive Care
Screening for Supportive Care Needs of Oncological Patients and Professionals - Evaluation of a Short PRO-question Set
The systematic recording of patient-reported symptoms and health-related quality of life (patient-reported outcomes, PROs) is a central component of oncological care.
- Conditions
- Patient Related Outcome Measures, Supportive Care, Patient Reported Outcome (PRO)
- Trial name
- Scope-PRO (NCT07505498)
- Where
- Germany
- Volunteers
- 900 people
- Sponsor
- University Medical Center Goettingen
Colorectal Cancer
A Trial to Evaluate Laparoscopic Versus Open Surgery for Colorectal Cancer
The purpose of this study is to evaluate oncological outcome of patients for T3 and T4 colorectal cancer undergoing laparoscopic versus open surgery.
- Trial name
- NCT00147134
- Testing
- open colectomy, laparoscopic colectomy
- Where
- 26 sites in Japan
- Volunteers
- 1,050 people
- Sponsor
- Haruhiko Fukuda
Stomach Neoplasm
Gastric Cancer' Textbook Oncological Outcome and Tumor Board Performance
The goal of this observational, no-profit, spontaneous, retrospective, monocentric study is to compare surgical and oncologic outcomes in patients affected by gastric cancer before and after the institution of the Tumor Board, a…
- Trial name
- GaC-TOP (NCT06923449)
- Testing
- Multidisciplinary Tumor Board
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS