Clinical trials: Operative Surgical Procedures
Dehydration in Children, Fluid Therapy
Boluses of Ringer's in Surgical Kids (BRiSK Study)
Traditional protocols for intravenous fluid administration in children who have undergone a major abdominal or thoracic operation are based on a landmark paper published in 1957 by Holliday and Segar.
- Trial name
- BRiSK (NCT05285371)
- Testing
- Urinalysis (UA), Complete Metabolic Panel (CMP), Glucose Stick Test (d-Stick)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Blood Loss, Surgical
Efficacy of Tranexamic Acid in Preventing Post Operative Blood Loss in Bone Sarcoma Patient
investigator will see the efficacy of tranexamic acid in limb salvage surgery patients which will prevent blood loss and help in conservation of blood products.
- Trial name
- NCT05427513
- Testing
- Tranexamic acid injection, normal saline
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Hysteroscopy, Minimally Invasive Surgical Procedures
Implementation of Hysteroscopy in Flanders and the Netherlands
By means of a questionnaire the investigators will study the implementation of hysteroscopy in Flanders and the Netherlands
- Conditions
- Hysteroscopy, Minimally Invasive Surgical Procedures, Polyp, Myoma
- Trial name
- NCT02853695
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- University Ghent
Fuchs Endothelial Corneal Dystrophy, Cataract (Post-operative Cataract Surgery Follow-up)
Postoperative CCT in FECD vs. Non-FECD
This single-centre, prospective, controlled, non-interventional observational clinical study aims to characterize early postoperative corneal thickness behaviour after routine phacoemulsification cataract surgery in eyes with…
- Trial name
- NCT07731945
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Vienna Hospital Association
Hematoma, Surgical Wound
Effectiveness of Khat on Eyelid Wound Healing After Oculoplastic Surgery - a Prospective Study.
The post operative routine after Oculoplastic Surgery includes usage of cold compressions for symptomatic relief and decreasing of the edema and local hematomas in the first few days after the surgery.
- Conditions
- Hematoma, Surgical Wound, Surgery, Eye Bruise
- Trial name
- NCT03917641
- Testing
- Khat leaves
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Patella Dislocation
Conservative Versus Operative - First Time Patella Dislocations
There is no consensus regarding whether rehabilitation or surgical management is best for the management of a primary patellar dislocation.
- Trial name
- NCT05533671
- Testing
- medial patellofemoral reconstruction, Non-operative group
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Third Molar
Does Post-operative Rinsing With a Monoject Syringe Result in as Much Post-operative Pain After Surgical Removal of Lower Impact Third Molars as no Post-operative Rinsing: a Randomized Controlled Equivalence Trial
Many authors have advocated different methods of treating alveolar osteitis. Despite many years of research, however, little progress has been made and so a study with large enough sample and standard outcome measures is…
- Trial name
- RITOR (NCT05860686)
- Testing
- Monoject syringe
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Isala
Molar, Third, Wisdom Teeth
Effect of Hilotherm Therapy on Post-operative Pain and Swelling Following Surgical Wisdom Tooth Removal
This study evaluates the efficacy of Hilotherm therapy on the incidence of swelling and pain following the surgical removal of lower wisdom teeth.
- Trial name
- NCT02284841
- Testing
- Hilotherm cooling face mask
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Opioid Use Disorder
SafeMedWaste At-Home, Environmentally-Friendly Opioid Disposal Kit for Orthopedic Post-Operative Surgical Patients to Reduce Opioids Available for Diversion
There is an urgent unmet medical need for a cost-effective, environmentally friendly, in-home opioid disposal solution for surgical patients that is clinically proven to reduce opioid use disorder that is substantiated with…
- Trial name
- Drug Disposal (NCT06215170)
- Testing
- SafeMedWaste
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- SafeMedWaste, Inc.
Mobile-based Mindfulness Intervention to Reduce Preoperative Anxiety, Pre-operative Anxiety
Effects of Mobile-based Mindfulness Intervention to Reduce Preoperative Anxiety for Patients Undergoing Elective Surgery
This study is a pilot randomized controlled trial (RCT) conducted at Tin Shui Wai Hospital to evaluate the effectiveness of a mobile-based mindfulness intervention in reducing preoperative anxiety among patients scheduled for…
- Conditions
- Mobile-based Mindfulness Intervention to Reduce Preoperative Anxiety, Pre-operative Anxiety, Postoperative Pain, Postoperative Use of Analgesics
- Trial name
- NCT07005973
- Testing
- mobile-based mindfulness intervention
- Where
- Hong Kong
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Hospital Authority, Hong Kong
Hysteroscopy
Green Hysteroscopy
The purpose of this study is to determine whether green draping in the operating room prior to a hysteroscopy results in a decreased operating room time.
- Trial name
- NCT06379841
- Testing
- Green Draping Procedure, Full Draping Procedure
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Emory University
Pelvic Organ Prolapse
Native Tissue Repair With Surgical Pelvic Organ Pessary - an RCT
This is an RCT looking at the primary outcome of composite success following anterior repair with native tissue at 6, 12, 24 months in two arms.
- Trial name
- NTRSPOP (NCT02808377)
- Testing
- Surgical Pelvic Organ Pessary
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Post Operative Pain
Comparison of Tramacet Versus Percocet in Post Surgical Patients
Opioid naive patients are randomized to receive either TRAMACET or PERCOCET at the time of discharge following mild to moderate pain risk surgery. The following will be assessed: 1) Brief pain inventory (BPI) for the month.
- Trial name
- NCT02361567
- Testing
- Tramacet, Percocet
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Post Surgical Pain, Post Operative Pain
Chronic Postsurgical Pain: Multivariate Prediction Model
The goal of this observational study is to identify the risk factors of Chronic Postoperative pain (or Chronic Post Surgery Pain - CPSP) three months after surgery and, subsequently.
- Conditions
- Post Surgical Pain, Post Operative Pain, Postoperative Pain, Chronic
- Trial name
- CPoP (NCT06417528)
- Testing
- Chronic Post Surgery Pain (CPSP)
- Where
- Italy
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva
Chronic Rhinosinusitis, Polyps
QOL Outcomes in CRS With Polyps
Chronic rhinosinusits (CRS) is common disease with reports of prevalence ranging from 4-16% in the western population. The main outcome measure for chronic disease treatment, such as CRS, is quality of life.
- Trial name
- NCT03144375
- Testing
- Medical optimization and education, Standard of Care sinus surgery
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Miami
Orthopaedic Surgery
Development of a Drill Guidance System to Aid Intra-operative Surgical Drilling
The Investigators have developed a camera based drill guidance system to improve the accuracy of surgical drilling. The aim of the study is to assess: Accuracy in vivo Safety Acceptability of use amongst surgeons and theatre staff
- Trial name
- NCT06309784
- Testing
- Drill Guidance System (DGS)
- Where
- 2 sites in United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Royal United Hospitals Bath NHS Foundation Trust
Education, Coaching
Structured Remote Surgical Coaching to Improve Operative Performance in Laparoscopic Cholecystectomy
Surgical coaching, defined as a constructive relationship that provides objective feedback to individuals about a broad range of factors influencing operative performance, is a key strategy for integrating adult learning theory…
- Conditions
- Education, Coaching, Surgical, Laparoscopic
- Trial name
- NCT04512560
- Testing
- Surgical Training using Structured Remote Surgical Coaching in addition to Conventional Surgical Training, Surgical Training using Conventional Training Program
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Boris Zevin
Postoperative Pain
Efficacy of EXPAREL in Comparison to Standard of Care for the Treatment of Post Operative Dental Implant Pain
This study is researching managing postsurgical pain by injecting both short-acting local anesthetics and EXPAREL® at the time of surgery and reviewing if it could reduce or eliminate the need for postsurgical opioids and improve…
- Trial name
- FAST (NCT02533440)
- Testing
- EXPAREL and Local Anesthetics, Oral Opioid and Local Anesthetics
- Where
- 3 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Bellaire Facial Surgery Center
Malignant Lung Neoplasm
Video-Assisted Intervention in Improving Recovery in Patients With Cancer Undergoing Lung Surgery and Caregivers
This pilot clinical trial studies a video-assisted intervention in improving recovery of patients undergoing surgery to remove lung cancer or cancer that has spread to the lung and their caregivers.
- Trial name
- NCT02345798
- Testing
- Standard Follow-Up Care, Caregiver-Related Intervention or Procedure, Educational Intervention
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Foot Surgery, Ankle Surgery
Liposomal Bupivacaine With Dexamethasone for Foot Surgery
This study aims to understand the ideal formulation to utilize in saphenous nerve and popliteal nerve blocks for foot and ankle procedures.
- Conditions
- Foot Surgery, Ankle Surgery, Post Operative Pain, Popliteal Nerve Block
- Trial name
- NCT06465992
- Testing
- Exparel 266 MG Per 20 ML Injection, Bupivacaine Hcl 0.75% Inj, Dexamethasone
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics