Clinical trials: Ophthalmic Surgery
Strabismus
Effect of Neuromuscular Blockade on the Oculomotor by Not Squinting Child
Strabismus is a common condition (4-6% of the population) . The screening and treatment is a public health issue. Indeed, beyond the disfigurement, this disease is very supplier of amblyopia which is definitive if it is not…
- Trial name
- STRABO (NCT02360969)
- Testing
- Examination of the eye
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Dry Eye, Cataract Surgery
Use of Prophylactic Lubricating Drops After Cataract Surgery
This is a randomised controlled trial to assess the use of prophylactic lubricant eye-drops for 6 weeks following uncomplicated, routine cataract surgery to improve patient satisfaction and symptoms of dry eye, compared to…
- Conditions
- Dry Eye, Cataract Surgery, Patient Related Outcome Measures, Patient Satisfaction
- Trial name
- NCT04131335
- Testing
- AEONTM Repair, Routine post-operative eye drops used.
- Where
- United Kingdom
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Agitation,Psychomotor
The Effect of Intraoperative Magnesium Sulfate Infusion on the Occurrence of Emergence Agitation
This study designed to evaluate the correlation between the effect of intraoperative magnesium sulfate infusion and the incidence of emergence agitation after pediatric ophthalmic surgery
- Trial name
- NCT03208452
- Testing
- Magnesium Sulfate, Normal saline
- Where
- South Korea
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Cholecystitis
Comparison of the Effects of Different PEEP Values With USG on Optic Nerve Sheath Diameter
Laparoscopic surgeries are now more popular because of the advantages such as shorter hospital stay, minimal scar. In order to perform laparoscopic surgery, pneumoperitoneum should be initiated.
- Trial name
- NCT06224868
- Testing
- insufflation, desufflation
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Baskent University
Dry Eye Disease (DED), Cataract
Impact of DED on the Accuracy of Preoperative Keratometry Values in the Calculation of IOL Power for Cataract Surgery.
This study looks at how dry eye disease can affect important eye measurements needed before cataract surgery. These measurements guide us in choosing the right artificial lens to implant, which is essential for achieving clear…
- Trial name
- NCT06989827
- Testing
- Preservative free artificial tear
- Where
- Croatia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Sestre Milosrdnice
Retinal Detachment, Proliferative Vitreoretinopathy
Internal Limiting Membrane Peeling in Retinal Detachment Surgery
Despite advances in surgical techniques over the recent decades, proliferative vitreoretinopathy (PVR) remains the main obstacle to successful rhegmatogenous retinal detachment (RRD) repair, accounting for nearly 75% of all…
- Trial name
- IMPURITY (NCT05538156)
- Testing
- Control group, Intervention group
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Diabetic Retinopathy, Type 2 Diabetes Mellitus
The Relationship Between Advanced Glycation Endproducts and Diabetes
The overall purpose of this COMIRB application is to perform a cross-sectional pilot study to aid in the design of a prospective epidemiologic study for an NIH grant application.
- Trial name
- NCT02662010
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Retinal Detachment, Epiretinal Membrane
PIONEER: Intraoperative and Perioperative OCT Study
OCT provides high-resolution information regarding the anatomic structure of the tissues of the eye in a 2-dimensional and 3-dimensional view. Much of this information is not able to be recognized by a clinician.
- Conditions
- Retinal Detachment, Epiretinal Membrane, Macular Hole, Fuchs Endothelial Dystrophy
- Trial name
- PIONEER (NCT02423161)
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Myopia
Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Moderate to High Myopia
The purpose of this study is to determine whether the MEL 80 Excimer Laser is effective in the treatment of moderate to high myopia (nearsightedness), when used as part of the Laser In Situ Keratomileusis (LASIK) procedure.
- Trial name
- NCT00762541
- Testing
- MEL 80 Treatment of High Myopia
- Where
- 5 sites in United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Cataract, Miosis
Nepafenac Versus Ketorolac Eye Drops in Prevention of Intraoperative Miosis During Cataract Surgery
This study aim at determining the efficacy of Nepafenac and Ketorolac in obtaining adequate intraoperative mydriasis and preventing miosis during cataract surgery.
- Trial name
- NCT03851172
- Testing
- Ketorolac Ophthalmic, Nepafenac Ophthalmic, Cyclopentolate Ophthalmic
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Assiut University
Corneal Diseases
Using in Vivo Confocal Microscope to Evaluate the Corneal Wound Healing After Various Ocular Surgeries
Although epi-keratome laser-assisted in situ keratomileusis (Epi-LASIK), penetrating keratoplasty and pars plana vitrectomy with corneal epithelial debridement for diabetic retinopathy are surgeries commonly performed, the…
- Trial name
- NCT00491439
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Optic Nerve Sheath Diameter, Caudal Block
Effect of Caudal Block Injection Rate on Optic Nerve Sheath Diameter in Pediatric Surgeries
Our prospective observational study will include patients between the ages of 1-7 years, ASA 1-2, who will undergo elective surgery under general anesthesia, whose consent was obtained by their parents for the procedure to be…
- Trial name
- NCT06187714
- Testing
- caudal block rate
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Myopia, High Myopia
Clinical Results of Small Incision Lenticule Extraction (SMILE) for the Correction of High Myopia
Small Incision Lenticule Extraction (SMILE) was introduced in 2011 using the VISUMAX femtosecond laser (Carl Zeiss Meditec, Jena, Germany). It is designed for correction of myopia and myopic astigmatism.
- Trial name
- NCT04110067
- Testing
- Small Incision Lenticule Extraction (SMILE) with Visumax (Carl Zeiss Meditec, Jena)
- Where
- Germany
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Suphi Taneri
Pneumoperitoneum
Intra-ocular Pressure and Ventilation
Background: Positive pressure pneumoperitoneum (PP) may involve adverse pathophysiological changes, including increased intra-thoracic and ocular pressure, when combined with standard ventilation.
- Trial name
- pressure (NCT02731404)
- Testing
- HFJV ventilation, IPPV ventilation
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Refractive Error
Evaluation of a Surgical Microscope Mounted Autorefractor When Used on Patients Lying in a Supine Position
The purpose of this study is to evaluate the accuracy and repeatability of an individually validated prototype autorefractor designed to be mounted on a surgical microscope.
- Trial name
- NCT01827748
- Testing
- Intraoperative Autorefractor IAR-1, Hartmann-Shack Auto Refractor
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Adventus Technology
Myopia
A Prospective Evaluation of Contrast Sensitivity and Disability Glare in Refractive Surgery, a Sub-Study of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel (WU # 2335-99)
The purpose of this study is to conduct a prospective assessment of small target contrast sensitivity and disability glare in refractive surgery.
- Trial name
- NCT00413868
- Testing
- LASIK, PRK, Small target contrast sensitivity and disability glare
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Myopia
Lacritin and Heparanase Levels in Human Tears After Laser Refractive Surgery
The purpose of this study is to measure tear lacritin and heparanase levels before and following surgery using a minimal risk procedure to collect tears from patients undergoing PRK or LASIK.
- Trial name
- NCT01049724
- Testing
- Tear collection
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Fort Belvoir Community Hospital
Anxiety, Strabismus
Does Anxiety in Children on the Day of Surgery Impact Compliance in the Ophthalmology Clinic?
The hypothesis is that pediatric patients with increased levels of anxiety on the day of surgery, in particular at point of anesthetic induction, will demonstrate decreased compliance with assessment in ophthalmology clinic…
- Conditions
- Anxiety, Strabismus, Compliance
- Trial name
- NCT02704442
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Queen's University
Cataracts
A Comparison of Prophylactic Antibacterial Efficacy of Besivance vs. VIGAMOX Prior to Cataract Surgery
To compare antibacterial efficacy of Besivance versus VIGAMOX for decreasing bacteria of the conjunctiva and lid margins in cataract patients prior to surgery after both 1 hour and 3 days of treatment.
- Trial name
- NCT01296542
- Testing
- Moxifloxacin Ophthalmic, Besifloxacin Ophthalmic
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bucci Laser Vision Institute
Myopia
Topography-guided LASIK Surgery
The investigators are analyzing outcomes of topography-guided LASIK surgery in participants with myopia and myopic astigmatism
- Trial name
- NCT03292419
- Testing
- Topography-guided LASIK
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Stanford University