Clinical trials: Ophthalmic Surgery
Primary Open Angle Glaucoma, Pseudoexfoliative Glaucoma
Phacotrabeculotomy Versus CCI+Phaco in Patients With Borderline Control of Intraocular Pressure
The purpose of the study is to determine whether combined cataract and glaucoma surgery (phacotrabeculotomy)is more effective in lowering intraocular pressure than cataract surgery alone in patients with borderline control of…
- Trial name
- NCT00346931
- Testing
- Phacoemulsification, implantation of intraocular lens, Phacoemulsification, Implantation of IOL, trabeculotomy
- Volunteers
- 9 people
- Sponsor
- Medical University of Vienna
Idiopathic Intracranial Hypertension
Surgical Idiopathic Intracranial Hypertension Treatment Trial
Randomized trial of adults (≥18 years old) with idiopathic intracranial hypertension and moderate to severe visual loss without substantial recent treatment who are randomly assigned to (1) medical therapy, (2) medical therapy…
- Trial name
- SIGHT (NCT03501966)
- Testing
- Acetazolamide, Optic Nerve Sheath Fenestration, Ventriculoperitoneal CSF Shunting
- Where
- 36 sites in United States, Canada and 1 more
- Volunteers
- 7 people
- Sponsor
- Jaeb Center for Health Research
Macular Holes
Air Tamponade and Non-supine Positioning in Macular Hole Surgery.
This is a prospective, multicenter, randomized non-inferiority trial, where the macular hole closure rate with intraocular air tamponade is compared to the closure rate with gas tamponade.The patients are randomized to receive…
- Trial name
- NCT03572725
- Testing
- Gas tamponade, Air tamponade
- Where
- 5 sites in Norway
- Volunteers
- 150 people
- Sponsor
- Helse Stavanger HF
Cataracts
Endothelial Cell Loss After Cataract Surgery
The purpose of this study is to compare two cataract surgical technique variations for removing the nucleus of the lens (central part of the lens) in terms of damage to the inner layer of the cornea which is called the…
- Trial name
- NCT00932191
- Testing
- Standard phacoemulsification, Reduced ultrasound phacoemulsification
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of California, San Francisco
Cataract, Dexamethasone
Dexamethasone Versus Metoclopramide for Prophylaxis of Nausea and Vomiting After Cataract Surgery
Postoperative nausea and vomiting (PONV) is a common consequence of ambulatory surgery, affecting up to 80% of high-risk patients and 20-30% overall.
- Trial name
- NCT07086118
- Testing
- 0.9% normal saline, Metoclopramide 10mg, Dexamethasone
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Alexandria University
Nasolacrimal Duct Obstruction
Study of Primary Surgical Treatment of Nasolacrimal Duct Obstruction in Children Less Than Four Years Old
The purpose of this study is: To report the success proportions of simple probing within different age groups of patients under 24 months of age.
- Trial name
- NLD1 (NCT00315289)
- Testing
- Nasolacrimal balloon catheter duct dilation, Nasolacrimal intubation, Simple Nasolacrimal duct probing
- Where
- 2 sites in United States
- Volunteers
- 973 people
- Sponsor
- Jaeb Center for Health Research
Myopia, Refractive Ametropia
Comparison of Two Rotational Alignment Methods for Astigmatism Correction in SMILE Surgery
Small incision lenticule extraction (SMILE) is a commonly used corneal refractive procedure for correcting myopia and myopic astigmatism.
- Trial name
- NCT07696468
- Testing
- Device-assisted cyclotorsion control during SMILE, Manual limbal marking-guided cyclotorsion adjustment during SMILE
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Post-Op Complication, Raised Ocular Pressure
Aqueous Release to Treat IOP Spikes Post-cataract Surgery
Intraocular pressure (IOP) rise after cataract surgery is an important and common problem. Over 300,000 cataract operations are done per year in the United Kingdom alone.
- Trial name
- NCT03500809
- Testing
- Aqueous release of the wound
- Volunteers
- 20 people
- Sponsor
- Bedford Hospital NHS Trust
Retinoblastoma, Retinal Neoplasms
Chemotherapy Treatment for Children With Intraocular Germ-Line Retinoblastoma
Retinoblastoma is an unusual cancer of early childhood involving tumor is both eyes or, in certain circumstances, one eye only. This condition is the result of an abnormal gene which makes both retinas (the back of the eye)…
- Trial name
- NCT00179920
- Testing
- Carboplatin, VP-16, Local Surgery
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Pupillary Disorders
Correlation of Pupillary Diameter Changewith Age and Anterior Chamber Depth After Cataract Surgery
PURPOSE: To assess the correlation between the change in pupil diameter, age and depth of the anterior chamber after 3 months of cataract surgery both in photopic and mesopic conditions.
- Trial name
- NCT04286646
- Where
- Spain
- Volunteers
- 55 people
- Sponsor
- Clinica Oftalmologica TACIR
Airway Complication of Anaesthesia, Laryngeal Mask Airway Removal
The Application of Lidocaine Cream on Oral Secretions of LMA Removal During the Recovery Period in Ophthalmic Surgical Patients Under General Anesthesia
The application of lidocaine cream on oral secretions of LMA removal during the recovery period in ophthalmic surgical patients under general anesthesia: a randomized controlled trial
- Conditions
- Airway Complication of Anaesthesia, Laryngeal Mask Airway Removal, Anesthesia Emergence, Secretion; Excess, Salivation
- Trial name
- LICOS (NCT06967064)
- Testing
- lidocaine cream
- Sponsor
- Sun Yat-sen University
Facial Plastic and Reconstructive Surgery, Periocular Diseases
AI-Assisted Facial Surgical Planning
Computer vision using deep learning architecture is broadly used in auto-recognition. In the research, the deep learning model which is trained by categorized single-eye images is applied to achieve the good performance of the…
- Conditions
- Facial Plastic and Reconstructive Surgery, Periocular Diseases, Orbital Diseases, Artificial Intelligence
- Trial name
- NCT04319055
- Where
- Taiwan
- Volunteers
- 17,932 people
- Sponsor
- National Taiwan University Hospital
Post Operative Endophthalmitis
Effectiveness and Safety of 0.5% Moxifloxacin Hydrochloride Ophthalmic Solution in Perioperative Sterilization in Patients Undergoing Ophthalmic Surgery
This is a non-interventional, uncontrolled, prospective, multicenter, post marketing surveillance study.
- Trial name
- NCT05413980
- Testing
- Moxifloxacin hydrochloride ophthalmic solution
- Where
- 9 sites in India
- Volunteers
- 102 people
- Sponsor
- Novartis Pharmaceuticals
Thyroid Eye Disease (TED), Graves Ophthalmopathy
Prospective Observational Study of Smartphone-Based AI Self-Monitoring During Non-Surgical Treatment for Thyroid Eye Disease (THYROSCOPE)
This prospective observational study evaluates the feasibility and clinical utility of a smartphone-based artificial intelligence (AI) self-monitoring system in adults with thyroid eye disease (TED) undergoing non-surgical…
- Conditions
- Thyroid Eye Disease (TED), Graves Ophthalmopathy, Thyroid Associated Ophthalmopathies
- Trial name
- THYROSCOPE-TED (NCT07623993)
- Testing
- Smartphone-based AI self-monitoring application (Glandy CAS/EXO/LID)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- THYROSCOPE INC.
Glaucoma, Ocular Hypertension
Safety and Efficacy of TimoD Sustained-Release Implant in Participants With Glaucoma or Ocular Hypertension Undergoing Cataract Surgery
The goal of this clinical trial is to test a new method to deliver an approved medicine called Timolol in the eye of participants with glaucoma or ocular hypertension and requiring cataract surgery.
- Trial name
- NCT07036510
- Testing
- TimoD implant, Injector system, Timolol eye drops 0.5%
- Where
- Panama
- Volunteers
- 42 people
- Sponsor
- EyeD Pharma
Cataract
Prophylactic Treatment: Lessdrops™ vs Standard Drops Regimen
To compare the use of a compounded eye drop containing an antibiotic, a non-steroidal and steroidal anti-inflammatory to standard of care that is the use of 3 different topical medications to prevent inflammation and infection…
- Trial name
- NCT03578276
- Testing
- Pred-Gati-Brom, Prednisolone acetate 1% ophthalmic suspension, Gatifloxacin Ophthalmic
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Carolina Eyecare Physicians, LLC
Dry Eye
Efficacy of Kera Sol Tears on Signs and Symptoms of Surgical Temporary Ocular Discomfort Syndrome (STODS) in Subjects Following LASIK
Collecting data using Kera Sol tear usage during the initial two-week post-operative period after Laser-Assisted In Situ Keratomileusis (LASIK) has on the signs and symptoms of surgical temporary ocular discomfort syndrome (STODS)
- Trial name
- NCT07155070
- Testing
- Kera Sol Eye Drops
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vance Thompson Vision
Cataract, Phacoemulsification
Correlation Between Postoperative Central Corneal Thickness and Endothelial Damage After Cataract Surgery
To study correlation between postoperative corneal edema and endothelial cell loss after cataract surgery by microcoaxial phacoemulsification.
- Trial name
- ECOCHI (NCT03972670)
- Volunteers
- 85 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Congenital Glaucoma
Study Aim to Compare the Effect of Different Technique of Airway Managment During Anaesthesia on the Haemodynamics and Intraocular Pressure. Patients Were Divided Into Three Groups of 25 Patients Each. (Group A); Patients Who Were Subjected to LMA Insertion (Group B ).
this study aim to compare the effect of different technique of airway managment during anaesthesia on the haemodynamics and intraocular pressure in pediatric patient undergoing congenital glaucoma surgery.
- Trial name
- Airway and IOP (NCT07504315)
- Testing
- laryngeal mask insertion, I gel mask insertion, Endotracheal tube insertion
- Volunteers
- 75 people
- Sponsor
- Sohag University
Retinoblastoma
Chemotherapy With or Without Radiation Therapy or Observation in Treating Young Patients With Advanced Retinoblastoma Who Have Undergone Surgery to Remove the Eye
RATIONALE: Drugs used in chemotherapy, such as carboplatin, vincristine, etoposide, and cytarabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00360750
- Testing
- carboplatin, cytarabine, etoposide
- Where
- 13 sites in United Kingdom
- Sponsor
- Children's Cancer and Leukaemia Group
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.