Clinical trials: Ophthalmology
Ophthalmology, Artificial Intelligence (AI)
Detection of Systemic Diseases Such as Hepatobiliary Diseases From Ocular Images Via Deep Learning
Oculomics is an emerging interdisciplinary field that deciphers multi-dimensional, high-throughput ocular data to predict, diagnose, and monitor systemic diseases and health span.In recent years, artificial Intelligence may…
- Conditions
- Ophthalmology, Artificial Intelligence (AI), Hepatobiliary Diseases, Systemic Diseases
- Trial name
- NCT07581925
- Testing
- Systemic diseases such as Hepatobiliary Disorders
- Where
- China
- Volunteers
- 730 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Mild Traumatic Brain Injury, Concussion, Binocular Visual Function
An Early Prospective Study of the Traq™ Device for Characterization of Binocular Ocular Function in Normal Subjects and Subjects With Recent Traumatic Brain Injury
The early prospective study of Traq™ (an investigational binocular ophthalmic neurodiagnostic device) will measure binocular ocular functions (bilateral foveal fixation, foveal binocularity, and fovea-tracked saccadic latency) in…
- Conditions
- Mild Traumatic Brain Injury, Concussion, Binocular Visual Function, Neuro-Ophthalmology, Saccadic Eye Movements
- Trial name
- REB-001 (NCT07742878)
- Testing
- Binocular ophthalmic neurodiagnostic device
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.
Rare Diseases, Ophthalmology
Identification of Cellular Biomarkers of Rare Eye Diseases in Adults
The cornea is the outermost transparent 'window' of the eye allowing light to enter and serving as the first-line immune and mechanical barrier.
- Trial name
- REVIBIO (NCT07063719)
- Testing
- Ophthalmological visit, Questionnaires, Blood sample collection
- Where
- 2 sites in France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Ophthalmology, Large Language Models
A Multimodal AI Agent for Ophthalmic Clinical Decision Support
This study is a multicenter randomized controlled trial evaluating the effectiveness and safety of EyeAgent, a multimodal artificial intelligence (AI) agent designed to assist ophthalmologists in clinical decision-making.
- Conditions
- Ophthalmology, Large Language Models, AI Agent, Eye Disease
- Trial name
- NCT07401459
- Testing
- EyeAgent AI system
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Neuro-Ophthalmology
Safety and Normative Data With Neos™
The goal of this clinical study is to collect standard data for the medical device neos™. neos™ is a system that shows images and measures the resulting eye movements and pupil size. Collecting standard data involves three steps.
- Trial name
- neos-SNOW (NCT07258212)
- Where
- 3 sites in Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- machineMD AG
Ophthalmology, Vision Screening
Community Interest in Vision Screening Technology
Virtual reality (VR) is a relatively new, emerging field within healthcare. Studies have analyzed public perceptions of virtual reality in healthcare using social media, but few have actually demonstrated and educated these…
- Trial name
- RTS2 (NCT04980430)
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Visual Snow Syndrome, Neuro-Ophthalmology
Neurofeedback in Visual Snow
Visual snow (VS) is a distressing, life-impacting condition with unrelenting and persistent disturbing visual phenomena. Disease onset is usually around age 20 and is characterized by continuous perception of innumerable…
- Trial name
- NCT04902365
- Testing
- neurofeedback
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Ophthalmology, Artificial Intelligence
Detection of Jaundice From Ocular Images Via Deep Learning
Our study presents a detection model predicting a diagnosis of jaundice (clinical jaundice and occult jaundice) trained on prospective cohort data from slit-lamp photos and smartphone photos, demonstrating the model's validity…
- Conditions
- Ophthalmology, Artificial Intelligence, Hepatobiliary Disease
- Trial name
- NCT05682105
- Where
- China
- Volunteers
- 1,633 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Ophthalmology, Lens Opacities
LensAge to Reveal Biological Age
Assessment of aging is central to health management. Compared to chronological age, biological age can better reflect the aging process and health status; however, an effective indicator of biological age in clinical practice is…
- Conditions
- Ophthalmology, Lens Opacities, Biological Age
- Trial name
- NCT05588921
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Ophthalmology
Study on the Effect of Eye-covering Pretreatment on Acute Delirium After General Anesthesia in Pre-school Aged Children
Participants (preschool children), because their cognitive ability and anti pressure ability are obviously weaker than adults, most of the children who have this kind of operation and anesthesia stressors will have perioperative…
- Trial name
- NCT04973150
- Testing
- To explore whether pretreatment with eye covering can reduce the incidence of acute delirium and the score of delirium after general anesthesia in ophthalmology pre-age children.
- Where
- China
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Artificial Intelligence, Ophthalmology
Artificial Intelligence System for the Detection and Prediction of Kidney Diseases Using Ocular Information
This is an retrospective and prospective multicenter study to develop and validate an artificial intelligent (AI) aided diagnosis, therapeutic effect assessment model including chronic kidney disease (CKD) and dialysis patients…
- Conditions
- Artificial Intelligence, Ophthalmology, Kidney Diseases
- Trial name
- NCT05223712
- Testing
- Diagnostic Test: Chronic Kidney Diseases
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Ophthalmology, Macular Degeneration
A Follow-up Physician Survey to Evaluate Physician Knowledge of Safety and Safe Use Information for Aflibercept Administered by Intravitreal Injection in Europe
With this follow up physician survey researcher want to collect the same data from all participants of the study using a highly structured questionnaire.
- Trial name
- NCT04067583
- Testing
- Physician questionnaire
- Where
- Germany
- Volunteers
- 454 people, healthy volunteers welcome
- Sponsor
- Bayer
Ophthalmology, Artificial Intelligence
Screening and Identifying Hepatobiliary Diseases Via Deep Learning Using Ocular Images
Artificial Intelligence may provide insight into exploring the potential covert association behind and reveal some early ocular architecture changes in individuals with hepatobiliary disorders.
- Conditions
- Ophthalmology, Artificial Intelligence, Hepatobiliary Disease
- Trial name
- NCT04213183
- Testing
- Hepatobiliary Disorders
- Where
- China
- Volunteers
- 1,789 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Ophthalmology, Photorefractive Keratectomy ("PRK")
Ocular Bandage Gel (OBG) Pivotal Trial in Patients Undergoing Photorefractive Keratectomy ("PRK")
Prospective, randomized, masked (reading center), controlled pivotal study of Ocular Bandage Gel (OBG) vs. a bandage contact lens (BCL) in subjects who have undergone bilateral photorefractive keratectomy (PRK).
- Conditions
- Ophthalmology, Photorefractive Keratectomy ("PRK"), Laser Assisted Surgery, Refractive Surgery
- Trial name
- NCT03938883
- Testing
- Ocular Bandage Gel (OBG), Bandage Contact Lens (BCL)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Ophthalmology
The Clinical Application of Artificial Intelligent(AI) Visual Inspection System
In this study, the investigators provide participants from ophthalmic clinic the AI visual inspection system and EDTRS in the purpose of seeking out a better way of visual inspection with high efficiency and accuracy, and report…
- Trial name
- AI (NCT03310216)
- Testing
- Order I of visual inspection, Order II of visual inspection
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University