Clinical trials: Opiate Use Disorder
Opioid Use Disorder, Addiction
Epigenetic Biomarker for Opioid Use Disorder
Study rationale Opioid use disorder (OUD) is a chronic and severe condition, defined by problematic opioid use, which results from interactions among sociological factors, psychiatric symptoms and life experiences, altogether…
- Trial name
- EBIOMOUD (NCT05419986)
- Testing
- Blood collection
- Where
- France
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Healthy
The Effects of ∆-9-THC and Naloxone in Humans
The purpose of this project is to examine the effects of mu-opiate antagonism on the rewarding and reinforcing effects of delta-9-tetrahydrocannabinol (THC), the main psychoactive ingredient of cannabis.
- Trial name
- NCT01591629
- Testing
- Naloxone, Delta-9-THC
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Yale University
Opioids; Harmful Use
Piloting a Naloxone Intervention in Philadelphia
The escalating opioid overdose epidemic is one of the most serious public health problems confronting the U.S. Death due to drug overdose is a significant and rising cause of mortality and morbidity in Philadelphia.
- Trial name
- NCT03305497
- Testing
- Mobile Phone Application
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Drexel University
Opiate Dependence, Depression
SSRI and Buprenorphine
This study is designed to test whether treatment of depressive symptoms using escitalopram improves adherence to Buprenorphine and reduces symptoms of depression for individuals receiving Buprenorphine through their medical…
- Trial name
- NCT00475878
- Testing
- escitalopram
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Pain
Use of On-Q Pump for Pain Post C-Section
The main purpose of this study is to examine if pain levels treated with intrathecal (IT) preservative-free morphine (PFM) after a cesarean section improve with the additional use of continuous subfascial wound infiltration with…
- Trial name
- NCT02579629
- Testing
- Ropivacaine 0.1%, Ropivacaine 0.2%, Normal saline
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Emory University
Opiate Use Disorder
Mindfulness-Oriented Recovery Enhancement (MORE) in Heroin Addiction
In this study, neuroimaging of reward processing, drug cue reactivity and inhibitory control is used before and immediately after 8 weeks of two types of group therapy in individuals with opioid addiction; clinical outcomes will…
- Trial name
- MORE (NCT04112186)
- Testing
- Behavioral group therapy #1, Behavioral group therapy #2
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai