Clinical trials: Oral Fluid Replacement
Osteoarthritis, Knee, Total Knee Arthroplasty
Oral Fluid vs IV Fluid After Primary TKA
The goal of this study is to compared efficacy of oral fluid and intravenous fluid after primary unilateral total knee arthroplasty.
- Conditions
- Osteoarthritis, Knee, Total Knee Arthroplasty, Oral Fluid Replacement
- Trial name
- NCT06288815
- Testing
- Oral fluid, IV fluid
- Where
- Thailand
- Volunteers
- 130 people
- Sponsor
- Thammasat University Hospital
Diarrhea, Children
Effectiveness of Oral Rehydration Therapy Supplemented With Zinc in the Management of Diarrhea Acute
Acute diarrhea is the third cause of infant mortality in the world causing 15% of all deaths in children under 5 years and is responsible for nearly 1.4 million deaths in developing countries.
- Trial name
- NCT02601742
- Testing
- Zinc group
- Volunteers
- 350 people
- Sponsor
- Hospital General Naval de Alta Especialidad - Escuela Medico Naval
Pain Management, Postoperative Pain
PCDD Generation 1 Oral Liquid Acetaminophen Delivery Evaluation
This prospective randomized pilot study evaluates the feasibility, acceptability, and preliminary efficacy of the Patient-Controlled Dispenser and Deactivator (PCDD) Generation 1 system for patient-controlled oral liquid…
- Trial name
- NCT07765238
- Testing
- PCDD Generation 1 system
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University
Gastroenteritis
Palatability of Oral Rehydration Solutions
The primary objective of this study is to compare the mean taste scores for three fruit flavored oral rehydration solutions in children aged 5-10 years old.
- Trial name
- NCT00689312
- Testing
- Enfalyte, Pediatric Electrolyte, Pedialyte
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- The Hospital for Sick Children
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
Reducing Orthostatic Intolerance With Oral Rehydration in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients
We and others have shown that many younger patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) have orthostatic intolerance (OI), i.e., they can't tolerate prolonged standing.
- Conditions
- Chronic Fatigue Syndrome, Myalgic Encephalomyelitis, Systemic Exertion Intolerance Disease (SEID), Postural Tachycardia Syndrome (POTS)
- Trial name
- NCT02854683
- Testing
- Normal Saline, Oral Rehydration Solution
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- New York Medical College
Diarrhoea
Effectiveness of Smecta in the Treatment of Acute Diarrhoea in Children
The purpose of this study is to evaluate the effectiveness of Smecta at decreasing stool weight, when compared to placebo, in the treatment of acute diarrhoea in children.
- Trial name
- NCT00352716
- Testing
- Smecta (Diosmectite), duration of treatment - 7 days
- Where
- 13 sites in Peru
- Volunteers
- 300 people
- Sponsor
- Ipsen
Diarrhea, Gastroenteritis
Rifaximin 200 mg Plus Oral Rehydration vs Oral Rehydration Alone in Children With Acute Diarrhea
The goal of this clinical trial is to learn how rifaximin 200 mg is processed in the body (pharmacokinetics) in children 6 to 11 years old with acute diarrhea that may be caused by bacteria.
- Conditions
- Diarrhea, Gastroenteritis, Bacterial Infection, Acute Diarrhea
- Trial name
- NCT07285785
- Testing
- Rifaximin 200 mg Tablet, Oral Rehydration Therapy (ORT)
- Where
- 10 sites in United States
- Volunteers
- 54 people
- Sponsor
- Bausch Health Americas, Inc.
Diarrhea
Antibacterial Treatment Against Diarrhea in Oral Rehydration Solution
This study hopes to demonstrate the potentials of a new form of therapy for childhood diarrhea, a major cause of morbidity and deaths in Bangladesh and other developing countries, and thus a priority for improving child health.
- Trial name
- NCT00937274
- Testing
- T4 phage cocktail test, Commercial T4 phage cocktail, standard oral rehydration solution (ORS)
- Where
- Bangladesh
- Volunteers
- 120 people
- Sponsor
- Société des Produits Nestlé (SPN)
Nausea and Vomiting, Postoperative
10% Carbohydrate Drink for Preventing Post-operative Nausea and Vomiting (PONV) After Spinal Morphine
PONV after intrathecal morphine, occurs up to 30-40 percent. The patients having TKR normally are female, obese and non-smoker which are risk factors for PONV.
- Trial name
- NCT01301404
- Testing
- 10% carbohydrate drink
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Mahidol University
Ultra-endurance Athletes With Gastrointestinal Symptoms
Effects of Probiotics and Nutritional Status on Exercise-Induced Symptoms, and Endurance Performance in Ultra-Endurance Athletes
Ultra-endurance athletes have been commonly endured extreme conditions during races and training sessions, resulting in exercise-associated clinical symptoms, including gastrointestinal symptoms, dehydration, and elevated…
- Trial name
- NCT04779281
- Testing
- Oral Rehydration Salts supplemented with L. Rhamnosus GG, Oral Rehydration Salts only
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Istanbul Medeniyet University
Acute Infectious Diarrhoea in Children
Isoleucine Added ORS in Children With Diarrhoea
Efforts are continuing to improve the efficacy of oral rehydration solution in terms of reducing the severity (stool volume) and duration of diarrhoea (enhancement of recovery).
- Trial name
- NCT01034228
- Testing
- ORS + Isoleucine, ORS without Isoleucine
- Where
- Bangladesh
- Volunteers
- 50 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Diarrhea Toddler
The Impact of Pre-emptive Home Delivery of ORS + Zinc on Treatment for Child Diarrhea
The aim of this clustered randomized controlled trial is to evaluate whether free and pre-emptive distribution of Oral Rehydration Salts (ORS) and Zinc at home increases the use of ORS to treat diarrhea cases among children under…
- Trial name
- NCT06444633
- Testing
- Community Sensitization + Household visit + Information + Free pre-emptive distribution of ORS+Zinc
- Where
- Nigeria
- Volunteers
- 102,650 people, healthy volunteers welcome
- Sponsor
- RAND
Dehydration
Oral Rehydration Solution in Healthy Adults
This is a prospective, randomized, controlled, blinded, crossover study to evaluate the effects of an oral hydration solution.
- Trial name
- NCT06130475
- Testing
- Oral Rehydration Solution (ORS), Water
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Anesthesia, Spinal, Cesarean Section
Post Spinal Anesthesia Hypotension and Preoperative Hydration
Study of the impact of preoperative oral rehydration on the incidence of spinal anesthesia-induced hypotension for scheduled cesarean section.
- Trial name
- NCT04450667
- Testing
- Nutricia PreOp
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brugmann University Hospital
Postoperative Delirium
Effects of Different Preoperative Oral Rehydration Protocols in Undergoing Thoracoscopic Radical Lung Cancer Surgery
This study aims to compare the new preoperative oral rehydration protocol (administering 50-100 mL of clear fluids or carbohydrate-rich beverages orally every hour until the patient arrives at the operating room) with the…
- Trial name
- NCT07042503
- Volunteers
- 420 people
- Sponsor
- Fujian Medical University Union Hospital
Diarrhea
Efficacy and Safety of a New Oral Rehydration Solution (Hipp ORS 200 Apple) in Children With Acute Gastroenteritis
It is generally recommended that oral rehydration should be used as first-line therapy to treat or prevent dehydration in children with acute gastroenteritis (AGE).
- Trial name
- NCT01467570
- Testing
- oral rehydration solution Hipp ORS Apple 200, ESPGHAN ORS
- Where
- Poland
- Volunteers
- 147 people
- Sponsor
- Medical University of Warsaw
Gastroenteritis
Is Electrolyte Maintenance Solution Required in Low-Risk Children With Gastroenteritis?
The objective of this study is to clarify the current standard of care by determining if Electrolyte Maintenance Solution (EMS) is truly the optimal fluid to be used in low-risk children who present to an Emergency Department…
- Trial name
- NCT01185054
- Testing
- ½ strength apple juice, Pediatric Electrolyte
- Where
- Canada
- Volunteers
- 624 people
- Sponsor
- The Hospital for Sick Children
Diarrhea
Impact of Home Zinc Treatment for Acute Diarrhea in Children
Background. Zinc deficiency is common in Africa. It has been shown in Asia that zinc as treatment for diarrhea can shorten the course of episodes of diarrhea, as well as prevent future episodes.
- Trial name
- NCT00530829
- Testing
- zinc
- Where
- Kenya
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Burn Any Degree Involving 20-29 Percent of Body Surface, Burn Any Degree Involving 30-39 Percent of Body Surface
Oral Rehydration Therapy in Burn Patients
In patients with moderate to severe thermal injuries (> 20% TBSA) adequate fluid resuscitation is the main priority to achieve successful outcomes.
- Conditions
- Burn Any Degree Involving 20-29 Percent of Body Surface, Burn Any Degree Involving 30-39 Percent of Body Surface, Burn Any Degree Involving 40-49 Percent of Body Surface, Burn Any Degree Involving 50-59 Percent of Body Surface
- Trial name
- ORT (NCT02124265)
- Testing
- CeraLyte 90
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Johns Hopkins University
Arthroplasty, Replacement, Knee
Traditional vs Oral Fluid Management in Total Knee Arthroplasty
Purpose: Evidence-based guidelines on optimal perioperative fluid management have not been established in patients undergoing orthopaedic surgery.
- Trial name
- NCT03719378
- Testing
- Pre Operative Oral Fluids
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Colorado Joint Replacement