Clinical trials: Oral Health, open to volunteers
Chronic Kidney Disease(CKD)
Effect of Oral Health Educational Program on the Oral Health Related Quality of Life in a Group of Children with Chronic Kidney Disease
Children with CKD are at higher risk for poor oral health28 due to factors such as compromised immunity, medication side effects, and dietary restrictions.
- Trial name
- CKD (NCT06879223)
- Testing
- Oral Health Educational Program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Children, Dental Caries
A Comprehensive Oral Health Intervention Program for Preschool and Primary School Children in Suzhou
This study aims to evaluate the effectiveness of a comprehensive oral health intervention program among preschool and primary school children in Suzhou, China.
- Trial name
- NCT07808203
- Testing
- Comprehensive Oral Health Intervention
- Volunteers
- 2,040 people, healthy volunteers welcome
- Sponsor
- Soochow University
Acute Lymphobkastic Leukemia, Medication Adherence
The AYA Oncology Self-care Movement
This trial will test the impact of a social media intervention for improving oral chemotherapy adherence among adolescents and young adults (AYAs) with acute lymphoblastic leukemia.
- Trial name
- #AYAOSM (NCT07724652)
- Testing
- Educational Website, #AYAOSM
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Northwestern University
Motivational Interviewing, Periodontitis
Motivational Interviewing and Subgingival Instrumentation Outcomes in Periodontitis
Motivational Interviewing (MI) represents a patient centered counselling approach designed to facilitate behaviour change by guiding patients through the exploration and resolution of ambivalence toward positive health actions.
- Conditions
- Motivational Interviewing, Periodontitis, Oral Hygiene
- Trial name
- NCT07618533
- Testing
- Motivational Interviewing, Oral hygiene instructions
- Where
- India
- Volunteers
- 66 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontal Disease, Diabete Mellitus
Oral Health and Systemic Diseases: Survey of General Practitioners
This cross-sectional observational study aims to assess the level of knowledge, clinical practices, and professional attitudes of General Practitioners (GPs) regarding oral health and its relationship with major systemic…
- Trial name
- NCT07604493
- Testing
- Questionnaire Survey
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Oral Health Behavior Change
SEHAT Virtual Oral Health Promotion for School Adolescents in Pakistan
The goal of this cluster-randomized trial is to learn if the SEHAT program works to improve oral health among school adolescents in Pakistan. It will also assess how the program affects oral health behaviors and knowledge.
- Trial name
- SEHAT (NCT07536958)
- Testing
- SEHAT Virtual Oral Health Education, Conventional Oral Health Education
- Where
- Pakistan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Shifa College of Dentistry
Prediabetes, Obesity & Overweight
Crocus Sativus Tepals Water Extract in Obesity and Prediabetes
The goal of this clinical trial is to determine the acute effects of ingestion of a cold aqueous extract of Crocus sativus tepals on postprandial glycemia and other indicators of metabolic health in patients with obesity and/or…
- Trial name
- ZAFRAN (NCT07261475)
- Testing
- Crocus sativus tepals cold aqueous extract, cold water
- Where
- Slovenia
- Volunteers
- 20 people
- Sponsor
- University of Primorska
Tooth Extraction, Postoperative Care
Effectiveness of Telephonic and Digital Postoperative Follow-up Communication Strategies on Patient Compliance, Clinical Recovery, and Quality of Life After Dental Extraction
Effectiveness of Telephonic and Digital Postoperative Follow-up Communication Strategies on Patient Compliance, Clinical Recovery, and Oral Health-related Quality of Life Following Dental Extraction (CONNECT Study - CONtinuous…
- Conditions
- Tooth Extraction, Postoperative Care, Patient Compliance
- Trial name
- CONNECT (NCT07751822)
- Testing
- Telephonic Postoperative Follow-up, Digital Postoperative Follow-up, Standard Postoperative Care
- Where
- Saudi Arabia
- Volunteers
- 216 people
- Sponsor
- King Saud University
Gingivitis, Plaque
Clinical Study to Collect and Analyze Dental Plaque and Oral Health Measures in a Population With High Plaque/Low Gingivitis and High Plaque/High Gingivitis
The objective of this clinical research study is to collect and analyze plaque and oral health measures in a population with high plaque/low gingivitis and high plaque/high gingivitis
- Trial name
- NCT07614490
- Testing
- sodium monofluorophosphate toothpaste
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Colgate Palmolive
Health Adult Subjects, Obesity & Overweight
A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Orally Administered TIX100 in Healthy Subjects
Randomized, Placebo-controlled Study to determine the safety and tolerability of multiple oral doses of TIX100 administered daily for 28 days to otherwise healthy overweight/obese subjects.
- Trial name
- NCT07675590
- Testing
- TIX100
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- TIXiMED, Inc.
Peri-Implantitis
ATR-FTIR and Raman Spectroscopy of Peri-Implant Crevicular Fluid in Peri-Implantitis
Peri-implantitis is an inflammatory condition affecting the tissues surrounding dental implants and may lead to supporting bone loss. Current diagnosis is mainly based on clinical and radiographic findings.
- Trial name
- NCT07864233
- Testing
- ATR-FTIR and Raman Spectroscopic Analysis of Peri-Implant Crevicular Fluid
- Volunteers
- 100 people
- Sponsor
- Necmettin Erbakan University
Eating Disorders, Oral Health
Oral Indicators for ED Screening
The main objective of this research project is to explore the capability of a standardized, evidence-based study tool (the OHEDs Checklist) in the early identification of oro-dental manifestations potentially indicative of an…
- Conditions
- Eating Disorders, Oral Health, Eating Disorders Symptoms
- Trial name
- OHEDS (NCT07295197)
- Where
- Italy
- Volunteers
- 461 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Space Maintenance, Gingival Health
Clinical Evaluation of 3-D Printed Partial Denture Space Maintainer
Primary dentition is the most suitable space maintainer for permanent teeth. However, as infants often lose their primary teeth too soon, using a space maintainer is the most efficient, long-lasting, and economical way to prevent…
- Trial name
- NCT06825273
- Testing
- space maintainer
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Non-Alcoholic Fatty Liver Disease
Effects of TOTUM-448 on Liver Fat Content, Cardiometabolic Risk Factors and Gut Microbiota Among Participants with MASLD
This clinical trial aims to investigate the effects of TOTUM-448, a mix of 5 plant extracts and choline, consumed at the daily regimen of two times per day, on liver fat content, cardiometabolic risk factors and gut microbiota…
- Trial name
- CARDIO-LIVER (NCT06704321)
- Testing
- TOTUM-448
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Valbiotis
Oral Health in Pregnancy and Early Childhood, Early Childhood Caries (ECC)
Midwives' Perspectives on Oral Health in Pregnancy and Early Childhood: A Cross-Sectional Online Survey
This study aims to explore how midwives in Germany perceive their professional role in the context of oral health of pregnant women and young children.
- Conditions
- Oral Health in Pregnancy and Early Childhood, Early Childhood Caries (ECC), Health Promotion by Midwives
- Trial name
- NCT07572799
- Volunteers
- 200 people
- Sponsor
- University Medical Center Goettingen
Osteopenia, Osteoporosis
Calcium-Rich Food Versus Calcium Carbonate for Bone Health
This study will compare adherence, tolerability, safety, and treatment satisfaction between a calcium-rich food and a traditional calcium carbonate supplement in women ages 40 to 90 who are at increased risk for osteoporosis.
- Conditions
- Osteopenia, Osteoporosis, Bone Health in Perimenopausal Women, Menopause Related Conditions
- Trial name
- NCT07763509
- Testing
- 500 mg calcium from milk-derived minerals, Calcium Carbonate 500 MG
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Cornell University
Dental Diseases
MOLAR: Mapping Oral Health and Local Area Resources
The goal of this clinical trial is to test the impact of a screening and linkage intervention for adverse social determinants of health (aSDoH) on oral health linkage to care for emergency department patients.
- Trial name
- NCT05688982
- Testing
- General information provision, Geographic information provision, Navigational assistance
- Where
- United States
- Volunteers
- 2,927 people
- Sponsor
- Massachusetts General Hospital
Medication Adherence, Atrial Fibrillation (AF)
SNAP AF-52: Dose Appropriateness and Adherence to Oral Anticoagulation in Adults ≥65 With Atrial Fibrillation in Primary Care (Ordu, Türkiye)
SNAP AF-52 is an ambidirectional observational registry conducted in family health centers (primary care) across Ordu, Türkiye, enrolling adults ≥65 years with a pre-existing diagnosis of atrial fibrillation.
- Conditions
- Medication Adherence, Atrial Fibrillation (AF), Direct Oral Anticoagulants (DOACs)
- Trial name
- SNAP AF-52 (NCT07242326)
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Kotyora Family Medicine Health Management and Education Association
Mechanical Ventilation, Infection Prevention
Oral Care Layered Enhancement for Improved Oral Hygiene in Intensive Care Units
The goal of the ORACLE study is to evaluate the impact of implementing a standardized oral hygiene bundle on outcomes in critically ill, mechanically ventilated patients.
- Conditions
- Mechanical Ventilation, Infection Prevention, Oral Care, Oral Hygiene, Oral Health
- Trial name
- ORACLE (NCT07129733)
- Testing
- Oral hygiene bundle
- Where
- 6 sites in Brazil
- Volunteers
- 4,800 people
- Sponsor
- Hospital do Coracao
Periodontitis, Periodontal Disease
Association of Periodontal Status and Smoking With Salivary Inflammasome Markers
The aim of this study is to evaluate the relationship between periodontal status and salivary levels of the inflammasomes NOD-like receptor family, pyrin domain containing 3 (NLRP-3), NOD-like receptor family, pyrin domain…
- Conditions
- Periodontitis, Periodontal Disease, Periodontal Health, Smoking
- Trial name
- NCT07312552
- Testing
- Periodontal examinations, Collection of saliva samples
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Uskudar University