Clinical trials: Oral Malodor
Oral Malodor (Halitosis), Oral Dryness
Effects of a 50+ Toothpaste on Halitosis and Oral Comfort in Healthy Adults
The goal of this clinical trial is to compare a toothpaste designed for adults aged 50 years and older with a standard toothpaste in orally healthy adults.
- Trial name
- HALI-50PLUS (NCT07780474)
- Testing
- 50+ Toothpaste, Standard Fluoride Toothpaste
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Oral Malodor
Four-Week Oral Malodor and Clinical Safety for a Concentrated Cosmetic Mouthwash
The objective of this study is to evaluate the safety of the concentrated mouthwash prototypes, and to evaluate the efficacy of the concentrated mouthwash prototypes in the control of oral malodor compared to a comparator…
- Trial name
- NCT06479096
- Testing
- Brush / Espresso Mild Prototype, Brush / Espresso Intense Prototype, Brush / Fresh Breath Oral Rinse
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Oral Malodor (Halitosis)
Evaluation of a Stannous Fluoride Dentifrice for Control of Oral Malodor
This single-center, randomized, double-blind, two-treatment crossover clinical study evaluated the safety and efficacy of a stannous fluoride-containing dentifrice compared with a sodium fluoride control dentifrice for the…
- Trial name
- NCT07425509
- Testing
- Sodium Fluoride Dentifrice, Stannous Fluoride Toothpaste (SnF)
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Oral Malodor
Controlling Oral Malodor by ClōSYS® Oral Rinse
The purpose of this Study is to assess the efficacy of two ClōSYS Oral Rinse products in human subjects in controlling oral malodor in partial fulfillment of the requirements for American Dental Association's (ADA) requirement…
- Trial name
- NCT03160560
- Testing
- ClōSYS® Unflavored Rinse, ClōSYS® Flavored Rinse
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rowpar Pharmaceuticals, Inc.
Bad Breath
Efficacy of Peppermint and Green Tea in Malodor
Background: Herbal remedies can have the role of prevention and control of bad breath Since in the previous studies, therapeutic and antibacterial effect of green tea and peppermint had been proven .we studied and compared the…
- Trial name
- NCT03053882
- Testing
- mouthwash
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Oral Malodor
Clinical Study on Malodor
This 3-week clinical study was designed to investigate the clinical efficacy on oral malodor of a 0.454% stannous fluoride toothpaste with nitrate and pyrophosphate (referred to as SNAP) compared to Colgate Cavity Protection…
- Trial name
- NCT06300905
- Testing
- test product, Control product
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Periodontitis, Halitosis
The Additional Effect of Tongue Scraping on Halitosis Parameters in Initial Periodontal Therapy
Periodontitis can lead to tooth loss which may impair chewing ability and aesthetics. In addition, periodontitis can give rise to halitosis.
- Conditions
- Periodontitis, Halitosis, Tongue Condition
- Trial name
- NCT06091228
- Testing
- tongue scraper
- Where
- Belgium
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Halitosis
Laser Tongue Debridement for Oral Malodor
Malodor is a multifactorial condition with oral pathology representing the main culprit and the tongue being the first to second contributor to the malodor.
- Trial name
- NCT04120948
- Testing
- Waterlase Express Laser System, Tongue scraper
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- New York Head & Neck Institute
Oral Bacteria, Halitosis
Effect of a Probiotic Water on Oral Health in Adults
The purpose of this study is to evaluate the effects of consuming a probiotic on salivary, plaque, and tongue bacteria, as well as oral malodor (bad breath).
- Trial name
- NCT04473404
- Testing
- Streptococcus salivarius DB-B5 - 2 billion CFU/day, Streptococcus salivarius DB-B5 - 10 billion CFU/day
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dose Biosystems Inc.
Gingivitis, Halitosis
Effect of Mouthwash Containing Camellia Sinensis Extracts on Oral Malodor
The purpose of this study is to determine effect of Mouthwash containing Camellia sinensis extracts on oral malodor and gingival inflammation in gingivitis subjects.
- Trial name
- NCT00932347
- Testing
- Camellia sinensis mouthwash
- Where
- 2 sites in Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Oral Malodor (Halitosis)
Effect of Toothpastes on Oral Malodor
This study aimed to evaluate the effects of different toothpaste formulations on oral malodor in young adults, addressing the lack of clinical evidence regarding propolis- and probiotic-containing toothpastes, which have…
- Trial name
- NCT07329062
- Testing
- Propolis Containing Toothpaste, Probiotic containing toothpaste, Phosphate-based formulation toothpaste
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Oral Malodor
A Clinical Study Conducted in the Bangkok, Thailand Area, to Investigate the Clinical Efficacy of a New Toothpaste
To investigate the clinical efficacy of a new toothpaste containing 0.454% stannous fluoride as compared to a regular fluoride toothpaste containing 0.76% sodium monofluorophosphate on oral malodor reduction via organoleptic…
- Trial name
- NCT07223073
- Testing
- 0.454% stannous fluoride, 0.76% sodium monofluorophosphate
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Oral Malodor, Halitosis
Effect of Miswak and Miswak Extract on Oral Malodor
The aim of this experiment is to investigate the effect of Miswak on oral malodor and to determine whether this effect -if present- is the result of the mechanical action of Miswak or the chemical effect of its extract
- Trial name
- NCT02628938
- Testing
- Miswak extract mouth wash, Miswak stick, Chlorohexidine gluconate
- Where
- Saudi Arabia
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Halitosis
Effect of Mouth Rinses in Oral Malodor
Bad breath or halitosis is caused by specific gases originating from the mouth or the expired air. In most cases the pathology lies within the mouth and in this case receives the name pathologic halitosis of oral cause or oral…
- Trial name
- MR2012 (NCT01747226)
- Testing
- Fluoride rinse, Halita, Meridol Halitosis
- Where
- Belgium
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Halitosis
Clinical and Microbiological Effects of a Mouthwash Containing Chlorine Dioxide
Previous research has shown the oxidizing properties and microbiological efficacies of chlorine dioxide (ClO2). However, no clinical studies have investigated its microbiological efficacies on periodontal and malodorous bacteria.
- Trial name
- NCT00748943
- Testing
- Chlorine Dioxide
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Tokyo Medical and Dental University
Halitosis
Association Between Dental Implants Properties and Malodor Production
Malodor production is bacterial in origin. The bacterial activity of anaerobic bacteria results in the breakdown of proteins and the production of foul smelling compounds.
- Trial name
- NCT00254839
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Halitosis
A Clinical Trial to Assess the Effects of a Mouthwash Containing Chlorine Dioxide on Oral Malodor
A mouthwash containing chlorine dioxide would be effective to reduce oral malodor.
- Trial name
- NCT00655772
- Testing
- Chlorine Dioxide
- Where
- Japan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Tokyo Medical and Dental University
Halitosis, Oral Malodor
Prevention of Oral Malodor With an Oral Sticker Containing Herbal Formula
the use of a herbal formulation containing sage, echinacea,lavender and mastic gum would prevent oral malodor if delivered in an appropriate delivery system to enable slow release of the active ingredients.
- Conditions
- Halitosis, Oral Malodor, Bad Breath
- Trial name
- NCT00250289
- Testing
- a mucosal sticker with herbal formula
- Where
- Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Oral Malodor
Clinical Investigation of Oral Malodor for Max Fresh Toothpaste Containing Zinc Citrate Versus a Commercially Available Regular Fluoride Toothpaste
The objective of this three-week clinical research study is to evaluate oral malodor for a toothpaste containing zinc citrate as compared to a commercially available regular fluoride toothpaste using the organoleptic method.
- Trial name
- NCT07398378
- Testing
- Max Fresh Toothpaste, Colgate Cavity Protection Toothpaste
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Oral Malodor
Clinical Study of the Effect of Two Experimental Lozenges on Oral Malodor After Single Use
The goal of this clinical trial is to compare the control of oral malodor between an investigational lozenge with the enzyme polyphenol oxidase plus green coffee extract or an investigational lozenge with color and flavor along…
- Trial name
- NCT05950529
- Testing
- Experimental lozenge with the enzyme Polyphenol oxidase and green coffee extract, Experimental lozenge with the enzyme Polyphenol oxidase, green coffee extract and flavor, No product
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S