Clinical trials: Oral Mucositis (Ulcerative) Due to Radiation
Head and Neck Cancer (H&N), Oral Mucositis (Ulcerative) Due to Radiation
Oral Care Program for Mouth Side Effects During Head and Neck Radiation Therapy
People having radiation therapy to the head and neck often develop painful mouth problems - mouth sores, dry mouth, mouth pain, trouble eating and drinking, and changes in taste.
- Conditions
- Head and Neck Cancer (H&N), Oral Mucositis (Ulcerative) Due to Radiation, Stomatitis (Oral Mucositis), Xerostomia Due to Radiotherapy
- Trial name
- OSEM (NCT07885033)
- Testing
- ORAL CARE PRODUCT KIT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- UNCANCER LLC
Oral Mucositis, Oral Mucositis (Ulcerative) Due to Radiation
Copaíba-based Mouthwash in Oral Mucotitis Prevention and Treatment in Oral Cancer Patients During Radioteraphy
Oral mucositis is the most significant acute toxicity of oral cavity radiotherapy. The available scientific evidence supports its preventive and therapeutic approach with low-level laser; however, this is unsuitable for tumor…
- Conditions
- Oral Mucositis, Oral Mucositis (Ulcerative) Due to Radiation, Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy, Oral Mucositis Due to Radiation
- Trial name
- NCT06708702
- Testing
- Copaíba mouthwash
- Where
- 2 sites in Brazil
- Sponsor
- Instituto Nacional de Cancer, Brazil
Oral Mucositis (Ulcerative) Due to Radiation
Efficacy of Ulinastatin for Reducing Radiation-Induced Oral Mucositis in Nasopharyngeal Carcinoma Patients
This is a phase 3, open-label, multicenter, randomized controlled phase III clinical trial. The purpose of this study is to evaluate the efficacy of ulinastatin, a kind of protease inhibitor, in the treatment of radiation-induced…
- Trial name
- UTI-RTOM-NPC (NCT03387774)
- Testing
- Cisplatin, Intensity Modulated Radiation Therapy, Ulinastatin
- Where
- China
- Volunteers
- 179 people
- Sponsor
- Sun Yat-sen University
Oral Mucositis (Ulcerative) Due to Radiation, Nasopharyngeal Carcinoma (NPC)
Taurine for the Prevention and Treatment of Radiation-induced Oral Mucositis in Patients With Nasopharyngeal Carcinoma
This clinical trial aims to understand whether taurine can prevent and reduce severe radiation-induced oral mucositis in patients with nasopharyngeal carcinoma undergoing radiotherapy.
- Trial name
- NCT07567742
- Testing
- Taurine
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Sun Yat-sen University
Oral Mucositis (Ulcerative), Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy
Multicentre Real-life Data Collection Study With CareMin650™ in the Prevention and Treatment of Oral Mucositis and Radio- and/or Chemo-induced Dermatitis
Most patients with cancer or haematological malignancies who receive chemotherapy - broadly defined to include targeted therapies and immunotherapy - and/or external beam radiotherapy may experience serious and disabling adverse…
- Conditions
- Oral Mucositis (Ulcerative), Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy, Oral Mucositis (Ulcerative) Due to Radiation, Dermatitis
- Trial name
- NéoPBM (NCT07054528)
- Where
- France
- Volunteers
- 33,000 people
- Sponsor
- Centre Hospitalier de Valenciennes
Oral Mucositis (Ulcerative) Due to Radiation
Aerosolized Mesenchymal Stem Cell-Derived Exosomes for the Prevention and Treatment of Radiation-Induced Oral Mucositis
Radiation-induced oral mucositis (RIOM) is an inevitable acute complication in radiotherapy for head and neck malignancies, characterized by a complex pathogenesis involving multiple biological processes.
- Trial name
- NCT07312656
- Testing
- mesenchymal stem cell-derived exosomes
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Guangxi Medical University
Oral Mucositis (Ulcerative) Due to Radiation
A Prospective Study on the Therapeutic Outcomes of Mebo and Tantum Verde in Patients With Oral Mucositis
This study aimed to assess the efficacy of MEBO® in the treatment of already established oral mucositis. This is a randomized controlled clinical trial.
- Trial name
- NCT07186114
- Testing
- MEBO Wound Ointment (MEBO), Tantum Verde® mouthwash
- Where
- 2 sites in Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Oral Mucositis (Ulcerative) Due to Radiation
Efficacy of N-acetylcysteine in Preventing Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients.
A prospective, randomized, controlled, parallel clinical trial will be conducted at Clinical Oncology and Nuclear Medicine Center at Mansoura University Hospital to assess the efficacy of N-acetylcysteine in the prevention of…
- Trial name
- NCT06354712
- Testing
- N-Acetyl-Cysteine with Institutional standard care, Institutional standard care
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Oral Mucositis (Ulcerative), Oral Mucositis (Ulcerative) Due to Radiation
Photobiomodulation to Demonstrate Safety and Reduce the Incidence of Oral Mucositis in Adult Head & Neck Cancer Patients
The overall purpose of this clinical study is to evaluate safety and efficacy of the MuReva Phototherapy System with a light delivery mouthpiece to reduce the severity of oral mucositis (OM) in adult patients with squamous cell…
- Conditions
- Oral Mucositis (Ulcerative), Oral Mucositis (Ulcerative) Due to Radiation, Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy, Head and Neck Cancer
- Trial name
- NCT03972527
- Testing
- Photobiomodulation, Routine Oral Care and Analgesia
- Where
- 12 sites in United States
- Volunteers
- 85 people
- Sponsor
- MuReva Phototherapy Inc.
Radiation Mucositis, Oral Mucositis (Ulcerative) Due to Radiation
Effectiveness of Topical Olive Oil in Prevention and Management of Radiation Induced Oral Mucositis
This research aims to investigate the effectiveness of topical olive oil application both clinically and biochemically as a suitable affordable treatment modality for prevention and management of radiation oral mucositis and its…
- Conditions
- Radiation Mucositis, Oral Mucositis (Ulcerative) Due to Radiation, Radiation-Induced Mucositis
- Trial name
- NCT05322421
- Testing
- Topical Olive Oil, Sodium bicarbonate 5% solution
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Salma Hesham Elhoufi
Head and Neck Neoplasms, Oral Mucositis (Ulcerative) Due to Radiation
Evaluating Chinese Medicine Oral Rinse for Irradiated Oral Mucositis in Head & Neck Cancer Patients
Approximately 60% and 90% of patients with head and neck (H\&N) cancers receiving standard radiotherapy (RT) and chemoradiotherapy (chemo-RT) will develop oral mucositis respectively.
- Conditions
- Head and Neck Neoplasms, Oral Mucositis (Ulcerative) Due to Radiation, Chinese Medicine Oral Rinse
- Trial name
- NCT05664906
- Testing
- Chinese Medicine Oral Rinse Formula-I (CMORF-I), Standard Care
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
Head and Neck Cancer, Oral Mucositis (Ulcerative) Due to Radiation
Efficacy and Safety of CareMin650 for Prevention of Oral Mucositis in HNC Patients Starting Radiotherapy
Oral mucositis (OM) can affect up to 90% of head and neck cancer (HNC) patients treated with radiation therapy (RT). The Mucositis Study Group of the Multinational Association of Supportive Care in Cancer and International…
- Conditions
- Head and Neck Cancer, Oral Mucositis (Ulcerative) Due to Radiation, Radiation Therapy Complication
- Trial name
- PrOMiSE (NCT04699487)
- Testing
- Photobiomodulation
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- NeoMedLight
Oral Mucositis (Ulcerative) Due to Radiation
Melatonin for Prevention of Radiation Induced Oral Mucositis
The main aim of this study was to evaluate the effectiveness of melatonin in prevention of radiation induced oral mucositis clinically and biochemically.
- Trial name
- NCT03833570
- Testing
- Rapid Release Capsules Melatonin, 10 mg, Miconaz oral gel, BBC oral spray
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hams Hamed Abdelrahman
Oral Mucositis (Ulcerative) Due to Radiation
Dexpanthenol Mouthwash to Treat Oral Mucositis
Oral mucositis can be a significant problem for cancer patients. It is typically associated with pain and increased risk of infection and can lead to impaired nutritional status and inadequate hydration.it can be seen in the…
- Trial name
- NCT01318889
- Testing
- Dexpanthenol
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Shahid Beheshti University of Medical Sciences