Clinical trials: Oral Submucous Fibrosis
Oral Submucous Fibrosis
Topical Application of Curcumin Orabase in Oral Submucous Fibrosis (OSMF)
Curcumin (diferuloylmethane) is the chief component of the spice turmeric and is derived from the rhizome of the East Indian plant Curcuma longa.
- Trial name
- NCT02645656
- Testing
- Curcumin Arm
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Oral Submucous Fibrosis
Evaluation of Auto Antibodies in Oral Sub Mucous Fibrosis
The etiology of OSMF is considered to be multifactorial. However, Role of autoimmunity had been suggested as one of the factors but remains unproven.
- Trial name
- NCT03011086
- Where
- India
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Oral Submucous Fibrosis
Effect of Laser Photobiomodulation in Improving Mouth Opening in Oral Submucous Fibrosis
This a patient and outcome assessor blinded, multiple arm, randomized placebo controlled clinical trial. The goal of the study is to study the adjunctive effect of 940nm laser photobiomodulation therapy (PBMT) in precancerous…
- Trial name
- OSMFPBMT (NCT06639009)
- Testing
- 940nm diode laser photobiomodulation, Conventional non -Invasive management in Oral Submucous fibrosis
- Where
- India
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Dr. Shalini Gupta
Oral Cancer, Oral Leukoplakia
Oral Cancer Screening and Education in Hong Kong
This study will be conducted to obtain data on oral cancer risk factors to generate machine learning models with good predictive accuracy for stratifying individuals with high-oral cancer risk and delineating high-risk and…
- Conditions
- Oral Cancer, Oral Leukoplakia, Oral Submucous Fibrosis, Proliferative Verrucous Leukoplakia
- Trial name
- NCT04487938
- Testing
- No intervention utilised
- Volunteers
- 3,190 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
The Study Focuses on the Saliva as Potential Source of Early Detection of Oral Cancer
EVALUATION OF SALIVA AS LIQUID BIOPSY FOR EARLY DETECTION OF ORAL CANCER IN PATIENTS WITH ORAL-SUBMUCOUS FIBROSIS (OSMF)
Oral cancer is the top cancer in Pakistan, accounting for 27%, and it has a high mortality rate due to late-stage diagnosis. It primarily affects the lips, tongue, cheeks, and floor of the mouth.
- Trial name
- Sal (NCT07122128)
- Testing
- saliva a a diagnostic tool for early detection of oral cancer
- Where
- Pakistan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Triamcinolone, Pentoxifylline
Comparison of Triamcinolone With Pentoxifylline and Vitamin- E Efficacy in the Treatment of Stage 2 and 3 Oral Submucous Fibrosis
To compare the efficacy of Triamcinolone with Pentoxifylline and Vitamin E in patients with stage two and three oral submucous fibrosis.
- Conditions
- Triamcinolone, Pentoxifylline, Vitamin E, Oral Submucosa Fibrosis
- Trial name
- NCT05660694
- Testing
- Triamcinolone, Pentoxifylline with Vitamin E
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Oral Submucous Fibrosis
Epithelial Mesenchymal Transition Markers in OSMF
Oral Sub mucous Fibrosis (OSMF) is essentially an imbalance between collagen metabolism and wound healing mechanism induced by arecanut chewing habit.
- Trial name
- NCT03732872
- Testing
- Biopsy tissue analysis, Saliva analysis
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- The Oxford Dental College, Hospital and Research Center, Bangalore, India