Clinical trials: Organophosphate Poisoning
Poisoning
Community Based Prevention/Control Project
This project is aimed at better understanding how children living in agricultural environments are exposed to pesticides, and how such exposures can be prevented or reduced.
- Trial name
- NCT00013767
- Testing
- Individual and Community education
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Disorders of Environmental Origin
Reducing Pesticide Exposure in Minority Families
This is a community-based participatory research program focusing on pesticide contamination in migrant farmworker families.
- Trial name
- NCT00014807
- Testing
- Reducing Pesticide Exposure in Minority Families
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Organophosphate Poisoning
The Use of Self-reported Symptoms as a Proxy for Acute Organophosphate Poisoning Among Nepali Farmers
The purpose of this study is to evaluate self-reported symptoms as a proxy for acute organophosphate poisoning by examining self-reported acute organophosphate poisoning symptoms and PchE activity in response to occupational…
- Trial name
- NCT02838303
- Testing
- Organophosphate
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Organophosphate Poisoning
Adding Nebulized Salbutamol to Intravenous Atropine and Oxygen in OP Poisoning
We hypothesize that salbutamol will speed removal of alveolar fluid compared to atropine alone in OP poisoned patients. We propose to compare the effect of two stat doses of nebulized salbutamol (2.5 mg; 5.0 mg), with nebulized…
- Trial name
- SalbutamolOP (NCT02160548)
- Testing
- Standard care, Standard care+ 2.5 mg Salbutamol, Standard care+ 5 mg Salbutamol
- Where
- Bangladesh
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sylhet M.A.G.Osmani Medical College
Organophosphorus Poisoning
A Study of Inhaled Atropine Sulfate in Healthy Adults
MicroDose Defense Products, LLC is developing an atropine dry powder inhaler (ADPI). This pilot study compares the pharmacokinetics (PK) of inhaled dry powder atropine as delivered by the ADPI to atropine delivery from the…
- Trial name
- NCT00947596
- Testing
- atropine sulfate
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- MicroDose Defense Products L.L.C.
Organophosphate Poisoning
Farming, Personal Protective Equipment, Nepal
According to the World Health Organization pesticide poisoning is a major health problem due to the millions of cases annually occurring worldwide.
- Trial name
- NCT02137317
- Testing
- LAPPE (locally adapted personal protective equipment)
- Where
- Nepal
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Medical Countermeasures, Organophosphate Poisoning
A Study to Evaluate the Intramuscular Administration of Scopolamine
To characterize the safety and tolerability profile of ascending doses of scopolamine hydrobromide trihydrate (Scopolamine HBT) administered by intramuscular (IM) injection.
- Trial name
- NCT04314713
- Testing
- Scopolamine Hydrobromide Trihydrate
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Battelle Memorial Institute
Poisoning
Pesticide Exposure Pathways for Farmworker Children
This project is aimed at better understanding how children living in agricultural environments are exposed to pesticides, and how such exposures can be prevented or reduced.
- Trial name
- NCT00013754
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Rivastigmine Toxicity
A Double-Blind, Placebo-controlled Crossover Study of Repeat Rivastigmine Administration in Healthy Male Volunteers
Rivastigmine is a carbamate, approved by the FDA for the treatment of mild to moderate dementia associated with Alzheimer's and Parkinson's diseases.
- Trial name
- RIVA-1 (NCT00624663)
- Testing
- Rivastigmine
- Where
- 2 sites in Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Organophosphate Poisoning
Paraoxonase-1 Pseudo Cholinesterase Organophosphate Toxicity Enzyme in Prediction the Severity and Outcome of Acute Organophosphate Poisoning and Its Correlation With Pseudo Cholinesterase Enzyme Level.
The aim of the present study is to: Evaluate the serum Paraoxonase-1 level in cases with organophosphate compounds poisoning and to correlate it᾿s level with the severity, outcome of acutely organophosphate poisoned cases .
- Trial name
- NCT06108557
- Testing
- Serum Pararoxonase -1 level, Diagnostic Test: Serum pseudocholinesterase enzyme level
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Neuroinflammatory Response, Nerve Injury
Assessment of Nerve Damage Biomarkers in Acute and Chronic Organophosphate Toxicity
The aim of this observational study is to answer the following questions in individuals with acute and chronic exposure to organophosphates. The main questions to be addressed are 1.
- Conditions
- Neuroinflammatory Response, Nerve Injury, Nerve Damage, Neurotoxicity
- Trial name
- NCT06021262
- Testing
- exposure to organophosphates
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Alexandria University