Clinical trials: Orthodontic
Bone Loss, Vertical Alveolar Bone Loss
Bioactive Glass (Sol-gel) for Alveolar Bone Regeneration After Surgical Extraction
The purpose of the present research is to evaluate the effect of bioactive glass in bone regeneration immediately following extraction of mandibular and maxillary premolars.The hypothesis of the study assumes that this treatment…
- Conditions
- Bone Loss, Vertical Alveolar Bone Loss, Horizontal Alveolar Bone Loss
- Trial name
- NCT01878084
- Testing
- bioactive glass (sol-gel), empty extraction socket
- Where
- Egypt
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Malocclusion, Compliance, Patient
The Effectiveness of Electronic Reminders in Improving Elastic Compliance in Orthodontic Patients
Fixed orthodontic appliances in combination with intraoral elastics are a common and effective method use in the orthodontic correction of malocclusions. However, their success is largely dependent on the patient's compliance.
- Trial name
- NCT03144323
- Testing
- Reminders
- Where
- 2 sites in United Kingdom
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Orthodontic Treatment
Comparison of Periodontal Health, Bonding Time and Failure Between Direct and Indirect Fixed Retainer Placement Among Orthodontic Patients
The placement technique of retainers in both maxillary and mandibular arches can influence the time taken for bonding the retainer in the mouth of a patient which can in turn affect the patient´s response to the procedure.
- Trial name
- NCT07107100
- Testing
- a silicon jig/key is used to place/bond fixed retainer on teeth
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aga Khan University Hospital, Pakistan
White Spot Lesion
PREVALENCE OF WHITE SPOT LESIONS IN ENAMEL AFTER ORTHODONTIC TREATMENT IN YOUNG ADULTS
The aim of the study is to measure prevalence of enamel white spot lesions in enamel in young adults after orthodontic treatment.
- Trial name
- NCT06882304
- Testing
- orthodontic treatment
- Volunteers
- 368 people
- Sponsor
- Cairo University
Injectable Plasma-rich Fibrin Versus Low-Level Laser Therapy on Othodontic Movement
Assessment of Different Orthodontic Tooth Movements Assisted With Low-level Laser Therapy vs. Injectable Platelets-rich Fibrin
The present prospective clinical study will be undertaken for assessment of the effect of application of Injectable plasma-rich fibrin versus Low-Level Laser Therapy onthe rate of different orthodontic tooth movements,
- Trial name
- NCT05966987
- Testing
- Low-level Laser Therapy vs. Injectable Platelets-rich Fibrin
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Orthodontic Treatment Acceleration, Photobiomodulation Therapy
Photobiomodulation Therapy (PBMT) for Accelerating Maxillary Canine Movement Using Two Wavelengths (650 nm and 976 nm): A Split-Mouth Randomized Controlled Clinical Trial
movement using low-level laser therapy with different wavelengths. Participants will receive laser application during orthodontic treatment, and the rate of canine movement will be measured and compared between the study groups.
- Trial name
- PBMT-CAN (NCT07597304)
- Testing
- 650 nm Photobiomodulation Therapy, 976 nm Photobiomodulation Therapy
- Where
- Iraq
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kufa University
Pain Management, Root Resorption
Photobiomodulation Effect on Vietnamese Orthodontic Patients
Since most orthodontic cases endure for 2 to 3 years or longer, patients are at a high risk of inflammatory root resorption and prolonged orthodontic pain, which is a common and unwanted side effect of their treatment.
- Conditions
- Pain Management, Root Resorption, Orthodontic, Tooth Movement
- Trial name
- NCT07276984
- Testing
- LED device
- Where
- Vietnam
- Volunteers
- 16 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Class II Canine, Intermaxillary Strength
Study Evaluating the Laser Diode Effect on the Kinetics of Orthodontic Tooth Movement (Protocol CINELASER)
It is a single-center, prospective clinical study of a medical device, controlled, randomized, non-stratified, double-blind (neither the patient nor the parents know which area is irradiated / practitioner who performs the…
- Conditions
- Class II Canine, Intermaxillary Strength, Elastics II, Multi Fasteners Orthodontic Treatment
- Trial name
- CINELASER (NCT02181439)
- Testing
- (LLLT Low Level Laser Therapy) SiroLaser advance
- Where
- France
- Volunteers
- 41 people
- Sponsor
- Nantes University Hospital
White Spot Lesion of Tooth
Fluoride Varnish, Ozone, Octenidin and WSLs in Orthodontic Patients
Objectives: to assess the efficiency of four prophylactic protocols on white spot lesions during orthodontic treatment: 1. professional mechanical tooth cleaning (PMTC)+fluoride varnish, 2.
- Trial name
- NCT04992481
- Testing
- PMTC, fluoride varnish, gaseous ozone therapy
- Volunteers
- 150 people
- Sponsor
- Pomeranian Medical University Szczecin
Orthodontic Appliances
Changes in Pulpal Blood Flow Between Conventional and Self-ligating Fixed Orthodontic Brackets During Leveling and Alignment Stage
Evaluate and compare initial changes in PBF between conventional and self-ligating fixed orthodontic brackets during leveling and alignment stage using 0.016" Nickle titanium (NiTi) and 0.016X0.022" NiTi archwires at different…
- Trial name
- NCT03780764
- Testing
- A Pre-adjusted edgewise brackets: 3M Gemini Unitek, 0.022" Roth prescription brackets, Self- ligating brackets: Unitek™ Gemini SL Self-Ligating Brackets, 0.022" Roth prescription brackets
- Where
- Jordan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Percentage of Deep Bite Correction
Assessment of Changes in Labioincisal Relationship in Deep Bite Correction by Twin Slot Orthodontic Bracket Clinical Trial Study.
Assessment Changes in Labio incisal Relationship in Deep bite Correction by Twin Slot Orthodontic Bracket; clinical trial study.
- Trial name
- NCT06677619
- Testing
- intrusion by reverse curve wire in cervical position of twin slot bracket
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Faculty of Dental Medicine for Girls
Basic Science, Orthodontic Appliance Complication
Clinical Effectiveness of the Calcium Chloride (CaCl2) Surface- Treated Orthodontic Mini Implant (OMI)
The goal of this split mouth, randomised control study was to compare the clinical effectiveness of surface treated Calcium Chloride orthodontic mini implant in orthodontic patients.
- Conditions
- Basic Science, Orthodontic Appliance Complication, Malocclusion
- Trial name
- NCT06607536
- Testing
- calcium chloride surface treatment in mini implant, Acid Etched
- Where
- Malaysia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universiti Teknologi Mara
Orthodontic Pathological Resorption of External Root
Efficacy of Injection Platelet-rich Fibrin(I-PRF) in Accelerate Alignment and Leveling
the aim of this study is to evaluate the effectiveness of injection I-PRF to accelerate alignment and leveling of the upper anterior teeth and reduce the time required for treatment.
- Trial name
- NCT04885842
- Testing
- injection I-PRF
- Where
- Syria
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Latakia University
Mouth Breathing
Speech-language Skills of Orthodontic Residents Through the Use of the "Interdisciplinary Orofacial Examination Protocol for Children and Adolescents"
This single-group pre-post study with external validation will be conducted on 29 orthodontic residents at the University of Pavia to assess their ability to recognize orofacial myofunctional disorders (OMD) before and after…
- Trial name
- NCT06887660
- Testing
- Orthodontic diagnosis
- Where
- Italy
- Volunteers
- 29 people
- Sponsor
- University of Pavia
Dental Plaque and Gingivitis, Oral Hygiene Reinforcement During Fixed Orthodontic Treatment
Mobile Application Push Notification in Improving Oral Hygiene Behaviour in Adolescent Orthodontic Patients
This research looks at whether using a mobile phone app that sends push-notification reminders can help adolescent orthodontic patients keep their teeth and gums cleaner during treatment.
- Trial name
- IMGS_EZGIGI (NCT07288853)
- Testing
- Ezgigi with push notification, EzGigi
- Where
- Malaysia
- Volunteers
- 78 people
- Sponsor
- Kumeran A/L Mohan
Oral Hygiene
Efficacy and Safety of the "Neo Pill" Device for Keeping Oral Hygiene in Patients with Fixed Orthodontic Appliance
Background: Orthodontic appliances interfere with oral hygiene and contribute to plaque retention, gingival inflammation and demineralization of enamel.
- Trial name
- NEOPILL (NCT06834139)
- Where
- Serbia
- Volunteers
- 143 people
- Sponsor
- University of Kragujevac
Orthodontic, Gingival Recession
The Impact of a 3D Imaging Tool on Reducing Gum Recession During Orthodontic Treatment With Aligners
This study investigates whether using 3D imaging technology (Cone Beam Computed Tomography or CBCT) for orthodontic treatment planning with aligners can reduce the risk of gingival recession in adult patients seeking dental arch…
- Conditions
- Orthodontic, Gingival Recession, Cone-Beam Computed Tomography
- Trial name
- GOPRO (NCT07513792)
- Testing
- 3D CBCT-Guided Orthodontic Treatment with Aligners, conventional orthodontic treatment planning
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University of Liege
Taste Disorders, Orthodontic Appliance Complication
Evaluation of Taste Sensation Changes During Fixed Orthodontic Treatment
The aim of this study is to determine the changes in taste perception that may occur before and after the initiation of treatment in patients undergoing fixed orthodontic treatment.
- Conditions
- Taste Disorders, Orthodontic Appliance Complication, Malocclusion
- Trial name
- TASTEFIXED (NCT06989736)
- Testing
- Taste Test
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Biruni University
Dentist-Patient Relations
Antimicrobial Photodynamic Therapy Applied in Orthodontic. Orthodontic Patients.
We demonstrated the use of the Antimicrobial Photodynamic Therapy as a coadjutant oral decontamination agent. It was also shown that SDS surfactant improves the antibacterial action of APDT when using Curcumin as the…
- Trial name
- NCT02337192
- Testing
- Curcumin, LED, Surfactant
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Caries, Dental Fillings
SEM Evaluation of the Quantity of microRepair® on Resin Composite Surfaces: an in Vivo Randomized Clinical Trial.
The aim of this study is to evaluate the quantity of Biorepair Total Protection toothpaste on composite surfaces inside oral cavity.
- Trial name
- NCT04808557
- Testing
- Biorepair Total Protection, Sensodyne Repair & Protect
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pavia