Clinical trials: Orthodontic Aligners
Orthodontic Pathological Resorption of External Root
Orthodontic Treatment With Clear Aligner
Three-dimensional Assessment of Root Resorption following treatment with clear aligners using Cone Beam Computed Tomography Design: A randomized, controlled, crossover, double-blind clinical study including twenty six adult …
- Trial name
- NCT06410105
- Testing
- CLEAR ALIGNERS
- Where
- Syria
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Latakia University
Orthodontic Aligner, Microbial Colonization
Microbial Colonization in Three Dimensional (3D) Printed Orthodontic Clear Aligners
This study is being done to compare conventional clear aligners with 3D printed clear aligners to assess if there is any significant difference between the microbial colonization of these appliances.
- Trial name
- NCT07143370
- Testing
- Thermoformed clear aligner, 3D printed clear aligner TC-85, 3D printed clear aligner TA-28
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Gingivitis, Dental Plaque
Clear Aligner Cleaning: Brushing, Chlorhexidine, and BlueM Effects on Oral Microbial Ecology and Periodontal Indices
This randomized crossover study will assess how three aligner-cleaning methods affect early supragingival oral microbial ecology and periodontal health in adults using clear aligners.
- Trial name
- NCT07307716
- Testing
- Mechanical toothbrushing (fluoride toothpaste), Chlorhexidine mouthwash (0.2%), Oxygen-based cleanser
- Where
- Saudi Arabia
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Orthodontic Pathological Resorption of External Root, Complication of Personal Oral Hygiene
Comparison of Oral Hygiene & Root Resorption During Orthodontic Treatment
Orthodontic treatment has been traditionally carried out with fixed appliances involving the use of stainless steel brackets and archwires.
- Trial name
- RCT (NCT02745626)
- Testing
- Appliance
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- UConn Health
Mandibular Dental Crowding
Effects of Micro-osteoperforations on Lower Anterior Crowding Using Clear Aligners
this randomized controlled trial is designed to compare between clear aligner therapy in alleviating mandibular anterior crowding alone versus with micro-osteoperforations
- Trial name
- NCT07169968
- Testing
- clear aligners group, micro-osteoperforations group
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Malocclusion
Impact of Clear Aligners and Metal Brackets on Nutritional Status
This study aims to investigate the effect of clear aligners and traditional brackets on the nutritional status of orthodontic patients.
- Trial name
- NCT05936463
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Orthodontic Tooth Movement
Clinical Trial to Assess the Efficacy of Reducing the Aligners' Wear Protocol
The hypothesis of this project is that replacing the current 7-day wear protocol with a 3-day wear protocol, while integrating less tooth movement per aligner (reduce the amount of activation per aligner) may produce more…
- Trial name
- NCT05905224
- Testing
- Invisalign 7-day wear protocol, Invisalign 3-day wear protocol
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Florida
Orthodontic Aligners
Difference Between Pressing and Vacuum Techniques in Fabrication of Orthodontic Aligners in Cases With Crowding: A Cross-sectional Study
This cross sectional study is aiming to compare 2 methods of clear aligner fabrication.
- Trial name
- NCT06231888
- Testing
- Aligner
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Crowding of Anterior Mandibular Teeth
Evaluating the Efficacy of Micro-Osteoperforations Technique on the Orthodontic Tooth Movement Acceleration in Moderate Mandibular Anterior Crowding Cases Treated With Clear Aligners
Patients with moderate mandibular anterior crowding will be treated in this study. The efficacy of micro-osteoperforations technique by special drill in accelerating orthodontic tooth movement during clear aligners therapy will…
- Trial name
- NCT05492773
- Testing
- Micro-osteoperforations Technique, Active comparater
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hama University
Malocclusion
Tunnel Attachments With Clear Aligners vs Clear Aligners
Incorporating wire threaded custom tunnel attachments with clear aligner therapy is a novel approach developed to address the shortcomings of the currently available orthodontic systems.
- Trial name
- NCT04130477
- Testing
- Tunnel attachments and light Nickel Titanium wire, Clear Aligner therapy
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Harvard School of Dental Medicine
Pain, Anxiety
Comparison of Subjective Experiences Between Patients Receiving Clear Aligners or Fixed Appliances
This study aimed to compare experiences between adult patients receiving clear aligners and fixed appliances during the initial stage of orthodontic treatments.
- Conditions
- Pain, Anxiety, Quality of Life
- Trial name
- NCT03656471
- Testing
- clear aligners or fixed appliances
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Orthodontic Tooth Movement
GCF Volume Changes in Aligners and Fixed Appliances
Orthodontic tooth movement induces biological responses in periodontal tissues that can be reflected by changes in gingival crevicular fluid (GCF).
- Trial name
- GCF-OTM (NCT07480538)
- Testing
- Clear Aligner Therapy, Fixed Appliance
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
White Spot Lesion
The Effect of Fluoride Varnish on White Spot Lesion in Clear Aligner Orthodontic Patients
Fluoride varnish is being applied on the teeth surfaces of patients undergoing orthodontic treatment just before receiving their clear aligners.
- Trial name
- NCT06403371
- Testing
- Fluoride varnsh, Normal saline
- Where
- Jordan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Orthodontic Aligners
The Efficiency of Clear Aligners in Maxillary Molar Distalization: A Randomized Clinical Trial.
The aim of this study is to evaluate the accuracy of clear aligners on the amount of the maxillary molar distalization.
- Trial name
- Aligner (NCT06330571)
- Testing
- Molar distalization by aligners with attachment
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Orthodontic Aligners
Difference Between Pressing and Vacuum Techniques in Fabrication of Orthodontic Aligners in Cases With Spacing: A Cross-sectional Study
This cross sectional study is aiming to compare 2 techniques of clear aligners fabrication identifying which is better.
- Trial name
- NCT06231875
- Testing
- Press
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pathological Resorption of External Root
3D Evaluation of Clear Aligners Versus Fixed Orthodontic Treatment of Lower Anterior Crowding
Evaluate and compare clear aligners versus fixed orthodontic treatment of lower anterior crowding with the use of cone-beam computed tomography within maximum 6 months or until correction of lower anterior crowding whichever is…
- Trial name
- NCT06510569
- Testing
- U lab aligners, oramco bracket
- Where
- 2 sites in Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Haidy Fekry
Root Resorption, Pain
Side Effects of Different Treatment Methods
this study aimed to compare the effects of fixed orthodontic treatment and clear aligner therapy on root resorption, periodontal status, pain experience and chewing performance.
- Conditions
- Root Resorption, Pain, Chewing Function
- Trial name
- NCT06709287
- Testing
- clear aligners, orthodontic metal bracket
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Orthodontic Pain (D013850), Orthodontic Patient Experience
Comparison of Different Debonding Techniques of Clear Aligner Attachments
The goal of this clinical trial is to compare two different methods for removing clear aligner attachments from tooth surfaces and to evaluate the pain levels and removal times associated with each method.
- Conditions
- Orthodontic Pain (D013850), Orthodontic Patient Experience, Orthodontic Aligners, Orthodontic
- Trial name
- NCT07259642
- Testing
- Adhesive removal plier followed by tungsten carbide bur, Tungsten carbide bur
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Halitosis, Probiotics
The Effect of Oral Probiotics on Oral Hygiene and Halitosis in Orthodontic Patients.
Brackets, bands, ligatures and wires in patients receiving orthodontic treatment with fixed appliances are areas that trap food and impede oral hygiene.
- Conditions
- Halitosis, Probiotics, Orthodontic Appliance Complication
- Trial name
- NCT05651503
- Testing
- Probiotics
- Where
- Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Athens
Dentinal Hypersensitivity, Plaque, Dental
Evaluation of Dental and Periodontal Health After IPR in Patients in Orthodontic Treatment With Clear Aligners
This study aimed to evaluate dental and periodontal health after interproximal enamel reduction and to compare Laser diode (a device used in the Orthodontic Program) and sodium fluoride (often used in the Orthodontic Program and…
- Conditions
- Dentinal Hypersensitivity, Plaque, Dental, Bleeding Gum
- Trial name
- NCT06685016
- Testing
- Evaluation of Dentin hypersensitivity with VAS scale
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli