Clinical trials: Orthodontics
Crowding
Alignment Efficiency of Two Thermal Activated Orthodontic Archwire Sequences
The aim of the present study was to compare the effectiveness of two alignment sequences with thermal activated archwires with different Af temperatures applied for the correction of mandibular anterior crowding
- Trial name
- NCT02415673
- Testing
- Fixed orthodontics appliance and arch wire
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Inflammation, Oxidative Stress
Oxidative-reductive Processes and the Degree of Inflammation in Saliva With Conventional Brackets and Clear Aligners
The purpose of this prospective observational study is to evaluate the differences in oxidative-reductive processes and the degree of inflammation in saliva during treatment with conventional brackets and clear aligners.
- Conditions
- Inflammation, Oxidative Stress, TNF-α
- Trial name
- NCT06507592
- Testing
- Saliva samples collection
- Where
- Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Tooth, Impacted
Effect of Interceptive Strategies on the Clinical Outcome of Maxillary Impacted Canines
This study aims to investigate the effect of 3 randomly applied interceptive measures (slow maxillary expansion, extraction of deciduous canines and no intervention) on maxillary canine impaction in patients with early mixed…
- Trial name
- NCT05629312
- Testing
- Maxillary expansion, Extraction of deciduous upper canines
- Where
- Belgium
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Orthodontics
Effect of Micro-osteoperforation on the Rate of Canine Retraction
The current study Is a split-mouth Randomized Controlled Trial that was performed to investigate three dimensionally, using digital models and Cone Beam Computed Tomography imaging, the effect of micro-osteoperforations (MOPs) on…
- Trial name
- NCT03450278
- Testing
- micro-osteoperforation
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Root Resorption
Root Resorption Accompanied Clear Aligners and Fixed Orthodontic Appliance
The aim of the study is to compare apical root resorption accompanied orthodontic treatment using clear aligners vs fixed appliances.
- Trial name
- NCT05232318
- Testing
- Leveling and alignment
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malocclusion, Angle Class I, Malocclusion; Angle Class II Division 1
Efficiency of Piezo-Corticision in Accelerating Orthodontic Tooth Movement
The purpose of this study is to provide evidence on the effectiveness, the efficiency and efficacy of Peizo-Corticission in accelerating orthodontic tooth movement and reducing orthodontic treatment time.
- Trial name
- NCT02549950
- Testing
- Peizocorticision, Conventional Orthodontic Mechanics
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- AL Yousef
Orthodontics, Orthodontic Appliance
A Commercial Available Tooth Positioner for the Treatment of Simple Orthodontic Relapse
Orthodontic relapse occurs in almost 80% of Orthodontic Treatment. The only prevention to phenomenon is the use of fixed retainers or life time active retention.
- Trial name
- NCT03332082
- Testing
- Tooth positioner
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Orthodontic Treatment
Curve of Spee: Speed of Leveling Using Different Orthodontic Archwires
The objectives if this study was to evaluate the efficacy of 3 different rectangular archwires in the correction of the curve of Spee (COS), to record the time needed to level excessive COS in the mandibular arch using the 3…
- Trial name
- NCT04549948
- Testing
- 0.017X0.025 Stainless steel, 0.019X0.025 Stainless steel, 0.021X0.025 B-Titanium archwire
- Where
- Jordan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Alignment
Changes in Pulpal Blood Flow of Teeth During Leveling and Alignment Stages of Orthodontic Treatment Using Clear Aligners
The aims of this study were to: - Evaluate PBF in upper and lower teeth during orthodontic alignment using fixed appliances (0.014" super elastic NiTi arch wire) at different time intervals (20min, 48h, 72h and 1 month) of…
- Trial name
- NCT03772795
- Testing
- Orthodontic Alignment
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Pathological Resorption of External Root
3D Evaluation of Clear Aligners Versus Fixed Orthodontic Treatment of Lower Anterior Crowding
Evaluate and compare clear aligners versus fixed orthodontic treatment of lower anterior crowding with the use of cone-beam computed tomography within maximum 6 months or until correction of lower anterior crowding whichever is…
- Trial name
- NCT06510569
- Testing
- U lab aligners, oramco bracket
- Where
- 2 sites in Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Haidy Fekry
Basic Science, Orthodontic Appliance Complication
Clinical Effectiveness of the Calcium Chloride (CaCl2) Surface- Treated Orthodontic Mini Implant (OMI)
The goal of this split mouth, randomised control study was to compare the clinical effectiveness of surface treated Calcium Chloride orthodontic mini implant in orthodontic patients.
- Conditions
- Basic Science, Orthodontic Appliance Complication, Malocclusion
- Trial name
- NCT06607536
- Testing
- calcium chloride surface treatment in mini implant, Acid Etched
- Where
- Malaysia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universiti Teknologi Mara
Malocclusion, Quality of Life
The Effect of Malocclusions on Oral Health Related Quality of Life
Malocclusions in adolescents may affect oral health related quality of life. The study aims at; 1. Evaluating two instruments measuring oral health related quality of life; "Child Perceptions Questionnaire 11-14" (CPQ 11-14)…
- Conditions
- Malocclusion, Quality of Life, Orthodontics, Adolescent
- Trial name
- NCT05038865
- Testing
- Malocclusion and Orthodontic Treatment
- Where
- 3 sites in Sweden
- Volunteers
- 675 people, healthy volunteers welcome
- Sponsor
- Malmö University
Malaligned Teeth, Crowding of Teeth
Effect of Different Adhesive Systems on White Spot Lesions During Fixed Orthodontic Treatment
The primary goal of this study is to compare the number of white spot lesions during fixed appliance therapy between self-etch and one-step bonding systems.
- Trial name
- NCT07753512
- Testing
- Self-etch adhesive, One-Step Adhesive, Conventional Bonding Technique
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Gingival Health
The Effects of Using Water Flosser Versus Interdental Brush on Gingival Health in Patients With Mandibular Bonded Retainer
This randomized controlled trial aimed to investigate and compare the effects of employing a water flosser versus an interdental brush on the gingival health of individuals with mandibular bonded retainers.
- Trial name
- NCT07054203
- Testing
- Water Flosser, Interdental Brush
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Palatal Expansion Technique
Evaluation of Hard and Soft Tissue Change During Maxillary Expansion Using a Computer-aided Design / Computer-aided Manufacturing Appliance.
Hard tissue changes during the transversal expansion of the maxilla using a CAD/CAM expansion appliance. Soft tissue changes during the transversal expansion of the maxilla using a CAD/CAM expansion appliance.
- Trial name
- NCT06246656
- Testing
- Maxillary Expansion
- Where
- Austria
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Orthodontic Pain (D013850), Malocclusion
Comparison of Three Orthodontic Separators for Pain, Plaque, and Tooth Separation
Orthodontic separators are small devices placed between teeth before fitting braces to create space for bands. This procedure may cause pain, discomfort, and changes in oral hygiene, which can affect plaque buildup and daily…
- Conditions
- Orthodontic Pain (D013850), Malocclusion, Orthodontic Treatment
- Trial name
- SEP-ORTHO (NCT07532044)
- Testing
- Elastomeric Separator, Kesling Separator, Tie wire separator
- Where
- Pakistan
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Islamabad Medical and Dental College
Orthodontics, White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Orthodontic Treatment on Oral Microbiota and Salivary Proteins
Study on the changes in oral microbiota during orthodontic treatment in patients aged 8-18 years. Orthodontic patients treated at Stomatology Hospital of Xi'an Jiaotong University from March 2025 to March 2027 will be recruited.
- Conditions
- Orthodontics, White Spot Lesions [Initial Caries] on Smooth Surface of Tooth, Caries, Dental
- Trial name
- NCT06824493
- Testing
- no interventions, No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Xi'an Jiaotong University
Orthodontic Pathological Resorption of External Root, Complication of Personal Oral Hygiene
Comparison of Oral Hygiene & Root Resorption During Orthodontic Treatment
Orthodontic treatment has been traditionally carried out with fixed appliances involving the use of stainless steel brackets and archwires.
- Trial name
- RCT (NCT02745626)
- Testing
- Appliance
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- UConn Health
Oral Hygiene, Photographs
Effect of Pre-treatment Photographs on Oral Hygiene Maintenance in Orthodontic Patients
Dental photography is an essential component of orthodontic treatment. Photographs enable the clinician to keep record of different stages of treatment.
- Trial name
- NCT06010797
- Testing
- Showing Pre-treatment photographs of the patient
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rehmat Memorial Post Graduate Dental Teaching Hospital
Malocclusion, Angle Class II
Comparison of Efficacy of Three Orthodontic Appliances
To investigate each treatment modality in its "optimal" environment to avoid operator experience bias. Therefore we propose to operate out of three "specialist centres" with specific units providing one modality alone Which of…
- Trial name
- NCT03450551
- Testing
- Twin Block, Herbst, Frog distalising appliance
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust