Clinical trials: Orthognathic Surgery
Mandible; Deformity, Surgical Healing
LLLT Effects on Inferior Alveolar Nerve (IAN) Recovery Post-orthognathic Surgery
Low-level laser therapy (LLLT) is a well-studied technique that has been shown to improve recovery time and reduce pain and swelling in patients undergoing surgery, including orthognathic surgery, and has no known negative…
- Conditions
- Mandible; Deformity, Surgical Healing, Orthognathic Surgery, Nerve Injury
- Trial name
- NCT04910074
- Testing
- Low-level laser therapy, Dummy LLLT
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Orthognathic Relapse
Effect of Botox Injection in Anterior Belly of Digastric on Skeletal Relapse Following Mandibular Advancement Surgery
The purpose of this study is to test whether Botox injection in anterior belly of digastric muscle in BSSO for mandibular advancement surgery could reduce the tendency of postoperative relapse.
- Trial name
- NCT05573581
- Testing
- Botox
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Evaluation of the Accuracy of Transferring the Virtual Planning to the Surgery
Accuracy of CAD/CAM Cutting Guides and Customized Titanium Plates for Virtual Planning Transfer in Bimaxillary Orthognathic Surgeries
In this research, we aim to use CAD/CAM surgical cutting guides for maxilla and mandible and customized titanium plates to guide all osteotomies and fixation of both arches.
- Trial name
- NCT04421144
- Testing
- orthognathic surgery
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Malocclusion
Nutritional Status in Orthognathic Surgery Patients
The aim of this study is to determine the effect of orthognathic surgery on nutritional status, anthropometric measurements, food consumption levels, physical activity levels, biochemical parameters, chewing ability and…
- Trial name
- NCT05591963
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lefort I Osteotomy
Waferless One Stage Segmental Lefort I Maxillary Positioning in Transverse Deficiency
In Maxillary transverse deficiency, is waverless lefort I multiple pieces osteotomy using virtually planned patient specific titanium implants feasible and does it provide accuracy? This prospective case series study evaluating…
- Trial name
- NCT03884699
- Testing
- Accuracy of planned transverse Maxillary distance using Mimics software after fixation using Patient specific implant
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Cairo University
Effect of Drugs
The Effect of Melatonin on Postoperative Pain Reduction After Orthognathic Surgery
Orthognathic surgery is a procedure performed to correct dentofacial deformities. It involves osteotomy at the facial skeleton. Considerable pain is expected in the early recovery period.
- Trial name
- NCT03995004
- Testing
- Melatonin, Dexamethasone Sodium Sulphate 4mg/1mL
- Where
- Hong Kong
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Cognitive Dysfunction, Postoperative Complications
The Effect of Hypotensive Anesthesia on Cognitive Functions in Orthognatic Surgery
The purpose of this study is to evaluate the effects of maintaining adequate cerebral oxygen saturation on patients undergoing orthognathic surgery.
- Trial name
- NCT06925711
- Testing
- Near-Infrared Spectroscopy (NIRS)
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medipol University
Dentofacial Deformities, Orthognathic Surgery
Quantitative Evaluation of Attention to Faces After Orthognathic Surgery With Eye-tracking
Dentofacial deformities refer to morphological anomalies of the jaws. Their development during growth determines the shape of the lower third of the face and the type of dental occlusion.
- Conditions
- Dentofacial Deformities, Orthognathic Surgery, Social Perception, Eye Tracking
- Trial name
- OCHIRO (NCT06494709)
- Testing
- photographs
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
OSA, OSAS
Maxillomandibular Advancement in the Treatment of Obstructive Sleep Apnea
ABSTRACT OBJECTIVES: To study the correlation between pharyngeal airway volume (PAV), the clinical indicators of obstructive sleep apnea (AHI, ESS), and the impact of orthognathic surgery on them.
- Conditions
- OSA, OSAS, Apnea, Obstructive Sleep, Orthognathic Surgery
- Trial name
- NCT03796078
- Testing
- Maxillomandibular advancement, monomaxillary surgery (isolated MaxS), monomandibullary surgery (MandS)
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centro Medico Teknon
Postoperative Nausea, Postoperative Vomiting
The Impact of Nasogastric Tube Gastric Decompression on Postoperative Nausea and Vomiting in Orthognathic Surgery
This study will compare the incidence of postoperative nausea and vomiting during the first 24 hours following corrective jaw surgery (orthognathic surgery) in patients with and without nasogastric tube gastric decompression.
- Trial name
- NCT06422793
- Testing
- No NG tube gastric decompression
- Where
- Canada
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Pain, Postoperative, Numbness
Lidocaine Versus Bupivacaine in Orthognathic Surgery
In this research study, we want to learn more about the impact of two different local anesthetics (bupivacaine and lidocaine) on patient experience following orthognathic (jaw) surgery.
- Conditions
- Pain, Postoperative, Numbness, Temperature Sensation, Perception of Touch
- Trial name
- NCT06450028
- Testing
- 10 cc of 0.25% bupivacaine hydrochloride with 1:200,000 epinephrine, 6.8 cc of 2% lidocaine hydrochloride with 1:100,000 epinephrine
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Pain, Postoperative
Does Preventive Dexketoprofen Reduce Pain After Orthognathic Surgery
Background The purpose of this study was to evaluate the effect of a single-dose intravenous dexketoprofen administration for preventive analgesia on postoperative pain and reducing swelling in double jaw surgery.
- Trial name
- NCT05303688
- Testing
- iv dexketoprofen trometamol (Arveles 50mg/2mL; UFSA, İstanbul, Turkey), Steril Salin (control)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Enhanced Recovery After Surgery, Hospital Stay
The Impact of Enhanced Recovery After Surgery in Orthognathic Surgery
Aim: Orthognathic surgeries are generally associated with blood loss, swelling, postoperative nausea vomiting (PONV), and pain. The aim of this study is to improve postoperative outcome in patients undergoing orthognatic…
- Conditions
- Enhanced Recovery After Surgery, Hospital Stay, Postoperative Nausea and Vomiting, Pain, Postoperative
- Trial name
- NCT04596774
- Testing
- Traditional Approach, Enhanced Recovery After Surgery (ERAS) Approach
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Jaw Deformity, Facial Asymmetry
Computational Modeling for Prediction of Acoustic Changes in Vowel Production Due to Orthognathic Surgery
A computational model of human sound production based on high quality anatomic measurements and physical laws of sound propagation cannot be accomplished without a comprehensive data set including both 3D-images of the speaker's…
- Trial name
- PUMA (NCT01887977)
- Testing
- MRI examination
- Where
- Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Macrogenia, Microgenia
Evaluation of The Accuracy of CAD-CAM Custom Made Titanium Miniplates In Positioning of the Genial Segment in Computer Guided Genioplasty
In patients with chin deformeties, will using a custom made titanium plate in the positioning of the genial segments give an accurate results in comparison to the preoperative planned osteotomy and move of the Genioplasty.
- Conditions
- Macrogenia, Microgenia, Miniplate
- Trial name
- NCT03647865
- Testing
- Osseous Genioplasty
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Malocclusion, Angle Class III
Evaluation of Surgical Outcomes of Patients Treated With the Surgery First Approach and Aligners
The purpose of this prospective study is to compare treatment outcomes and the quality of life of skeletal Class III patients treated with conventional fixed appliances and aligners undergoing Surgery-first approach.
- Trial name
- NCT05822271
- Testing
- Orthognathic Surgery
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Orthognathic Surgery
Retrospective Analysis of Anesthesia Procedure in Orthognathic Surgery
Using retrospective medical records to analyze the difference between the analysis of the correlation between operation time, blood loss, anesthesia methods, anesthesia medication, and postoperative recovery time
- Trial name
- NCT05316545
- Where
- Taiwan
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Tranexamic Acid, Orthognathic Surgery
The Effects of Tranexamic Acid on Blood Loss During Orthognathic Surgery
This study seeks to answer the question: Does a single pre-operative dose of tranexamic acid have a statistically significant reduction in blood loss during orthognathic surgery? If it does, this drug may begin to be used…
- Trial name
- TXA-OMFS (NCT03433144)
- Testing
- Tranexamic Acid Injectable Solution
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nick Emanuele
Preoperative Anxiety, Orthognathic Surgical Procedures
Visual Tools and Preoperative Anxiety in Orthognathic Surgery
This study evaluates whether adding visual tools to standard preoperative counseling can reduce anxiety in patients scheduled for bimaxillary orthognathic surgery.
- Trial name
- NCT07394881
- Testing
- Verbal İnformation, Animation Video Counseling, 3-D Skull Model Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara University
Orthognathic Surgery
Comparison Between Prebent Plates and Custom Plates After le Fort 1 in Orthognathic Surgery
patients with dentofacial deformities , who needs lefort 1 osteotomy to correct position of maxilla , are divided into two groups: one group receives custom titanium plates which is patient specific and the other group receives…
- Trial name
- customortho (NCT06188403)
- Testing
- Orthognathic surgery (lefort1)
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Alexandria University