Clinical trials: Osteoarthritis Hand
Osteoarthritis Hand
S-Asenosyl-L-Methionine vs Placebo for Osteoarthritis of the Hands
The primary objective of this study is to demonstrate the feasibility of evaluating SAMe tolerability, analgesic benefits, and daily functional improvement in patients with osteoarthritis of the hands compared to placebo.
- Trial name
- SAMe (NCT05363020)
- Testing
- S-Adenosyl-L-Methionine (Sam-E)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Osteoarthritis Hand
Efficacy of Surgical Joint Denervation in Painful Digital Osteoarthritis
Digital osteoarthritis is the second localization of symptomatic osteoarthritis, after the knee. Its cardinal symptoms are particularly intense pain and functional impairment in the case of the erosive form.
- Trial name
- DECAD (NCT05378841)
- Testing
- Surgical Denervation
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
CBD, Hand Osteoarthritis
Is Topical CBD Effective in Treating Thumb Joint Arthritis
Rationale: CBD is commonly being used as an over-the-counter treatment for arthritis-related pain, however no clinical trial has been performed to establish efficacy.
- Trial name
- NCT04611347
- Testing
- CBD, Shea Butter
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Thumb Osteoarthritis, Hand Injuries
Extracorporeal Shock Waves Therapy (ESWT) vs Exercise in Thumb Osteoarthritis
Osteoarthritis (OA) is a chronic joint disease with a high prevalence and a negative impact on the quality of life and a high economic burden.
- Trial name
- SWEX-TO (NCT06056765)
- Testing
- "Minilith", Storz, Swiss
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Hand Osteoarthritis
Testing of a New Joint Protection Program
The goal of this study is to to examine the feasibility of a full-scale trial on Helping Hand, a new Joint Protection Program for Hand Osteoarthritis and to examine the acceptability of the new Joint Protection Program.
- Trial name
- "Helping Hand" (NCT06963164)
- Testing
- Helping Hand - Joint Protection Program
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hand Osteoarthritis, Erosive Osteoarthritis
A 30-month Follow-up of MERINO Participants to Evaluate Long-term Effects of Methotrexate in Erosive Hand OA.
In response to the high prevalence of synovitis in hand osteoarthritis (OA) and its association with pain, there\'s a compelling rationale for investigating the efficacy of MTX in managing inflammatory erosive hand OA.
- Trial name
- MERINO:2 (NCT06281184)
- Testing
- Methotrexate, Treatment as usual
- Where
- Norway
- Volunteers
- 108 people
- Sponsor
- Diakonhjemmet Hospital
Hand Osteoarthritis
Happy Hands - an E-self-management Intervention for People With Hand Osteoarthritis
The main aim of this project is to assess the effect, cost-effectiveness and user experiences with using an e-self-management intervention in addition to treatment as usual compared to treatment as usual alone in patients with…
- Trial name
- HappyHands (NCT05568875)
- Testing
- e-self-management intervention (Happy Hands app), Treatment as usual
- Where
- 19 sites in Norway
- Volunteers
- 386 people
- Sponsor
- Diakonhjemmet Hospital
Osteoarthritis Hand, Neuropathic Pain
Capsaicin in Digital Osteoarthritis Versus Control
The objective of this multicentric, randomized controlled double-blind clinical trial is to demonstrate the efficacy of transdermal application of capsaicin in patients with painful digital osteoarthritis with a neuropathic pain…
- Trial name
- CADOR (NCT06444919)
- Testing
- Capsaicin 179 Mg Cutaneous Patch, Capsaicine low dose 0.04 %
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hand Osteoarthritis
Metformin Treatment of Patients with Hand Osteoarthritis
To compare metformin (2 g daily), or maximum tolerated dose, for 16 weeks with placebo as a treatment of hand osteoarthritis symptoms.
- Trial name
- METRO (NCT06367283)
- Testing
- Metformin
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Marius Henriksen
Hand Osteoarthritis
Cross-sectorial Management Program for People Living with Hand Osteoarthritis: a Randomised Controlled Pilot and Feasibility Study
To investigate the research design (pilot-RCT) and feasibility of the HANDY program for people with hand osteoarthritis (version 2.0).
- Trial name
- HANDY (NCT06794632)
- Testing
- HANDY occupational therapy intervention
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Parker Research Institute
Hand Osteoarthritis
Balneotherapy in Hand Osteoarthritis
There are a limited number of studies in the literature on the effectiveness of balneotherapy in hand osteoarthritis. The aim of this study was to evaluate the effects of balneotherapy on pain, manual skills, functionality and…
- Trial name
- NCT06702514
- Testing
- Exercise, Paraffin, Balneotherapy
- Volunteers
- 50 people
- Sponsor
- Afyonkarahisar Health Sciences University
Osteoarthritis Hand
Use of a Treated, Devitalized and Sterile Meniscus Segment (MENISC-T) in the Treatment of Scaphotrapeziotrapezoid Osteoarthritis
The purpose of this open, prospective and multi center trial is to evaluate the use of a treated, devitalized and sterile meniscus implant placed in joint interposition in the treatment of STT osteoarthritis.
- Trial name
- NCT05250726
- Testing
- MENISC-T
- Where
- France
- Volunteers
- 14 people
- Sponsor
- TBF Genie Tissulaire
Osteoarthritis, Hand Osteoarthritis
Balneotherapy and Peloid Therapy Impact Small Joint Diseases
This clinical trial investigates the effects of natural healing factors (mineral water and mud procedures) in combination with regular rehabilitation of patients with degenerative small joint disease.
- Conditions
- Osteoarthritis, Hand Osteoarthritis, Foot Osteoarthritis
- Trial name
- NCT06477393
- Testing
- Regular rehababilitation, Heat procedures, Healing mud application
- Where
- 2 sites in Lithuania
- Volunteers
- 130 people
- Sponsor
- Lithuanian University of Health Sciences
Thumb Osteoarthritis, Hand Osteoarthritis
Assessment and Comparison of Efficacy of Intra-Articular PRP and Corticosteroid in First CMC Joint OA Treatment
Aim: We aim to determine and compare the efficiency of single dose intra-articular (IA) platelet rich plasma (PRP) and corticosteroid (CS) injections for the treatment of first carpometacarpal joint osteoarthritis (1.
- Conditions
- Thumb Osteoarthritis, Hand Osteoarthritis, Platelet Rich Plasma, Corticosteroid
- Trial name
- NCT06657300
- Testing
- PRP, Corticosteroid
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya Training and Research Hospital
Complex Regional Pain Syndromes, Complex Regional Pain Syndrome Type I of the Upper Limb
Embodied Virtual Reality for Chronic Pain
Virtual reality creates interactive, multimodal sensory stimuli that have demonstrated considerable success in reducing pain. Much research so far has focused on VR's ability to shift patients' attention away from pain; however…
- Conditions
- Complex Regional Pain Syndromes, Complex Regional Pain Syndrome Type I of the Upper Limb, Complex Regional Pain Syndrome I (CRPS I), Complex Regional Pain Syndrome I of Upper Limb
- Trial name
- NCT05160038
- Testing
- Embodied virtual reality
- Where
- Switzerland
- Volunteers
- 29 people
- Sponsor
- University of Zurich
Osteoarthritis, Knee, Osteoarthritis Hand
The Halland Osteoarthritis Cohort
Osteoarthritis is the most common musculoskeletal disease and is characterized by cartilage destruction, osteophyte formation, subchondral bone sclerosis and cysts.
- Conditions
- Osteoarthritis, Knee, Osteoarthritis Hand, Osteoarthritis Generalized
- Trial name
- HALLOA (NCT04928170)
- Where
- Sweden
- Volunteers
- 312 people
- Sponsor
- FoU Center Spenshult
Hand Osteoarthritis
RANKL-blockade for the Treatment of Erosive Osteoarthritis (OA) of Interphalangeal Finger Joints
This is a randomized, double blind placebo controlled one-site proof-of-concept study in subjects with erosive osteoarthritis (OA) of interphalangeal (IP) finger joints.
- Trial name
- NCT02771860
- Testing
- denosumab, Calcium/Vit D supplementation
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Osteoarthritis Both Hands
Task Shifting in the Care for Patients With Hand Osteoarthritis
The main aim in this randomized controlled trial is to improve access to safe and effective care, professional practice and cost-effective utilisation of health care resources by testing if occupational therapist-led care is as…
- Trial name
- NCT03102788
- Testing
- Rheumatologist-led care., Occupational therapist-led care.
- Where
- 3 sites in Norway
- Volunteers
- 400 people
- Sponsor
- National Resource Center for Rehabilitation in Rheumatology
Osteoarthritis Hand, Lumbago
Cardiovascular Risk in Digital Osteoarthritis
The goal of this cross-sectional case control study is to investigate the cardiovascular risk in digital osteoarthritis. This study aims to compare the cardiovascular risk between group of patients with digital osteoarthritis and…
- Conditions
- Osteoarthritis Hand, Lumbago, Osteoporosis, Radiculopathy Lumbar
- Trial name
- RICARDI (NCT05923736)
- Testing
- Intima media thickness ultrasound, hand ultrasound, EndoPAT™ 2000 system
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hand Osteoarthritis
Water-filtered Infrared-A Radiation in Patients With Hand Osteoarthritis
The aim of this clinical trial is to evaluate the effects of water-filtered Infrared-A radiation on patients suffering from hand osteoarthritis.
- Trial name
- NCT06329219
- Testing
- water-filtered Infrared-A radiation
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Charite University, Berlin, Germany