Clinical trials: Osteoarthritis Pain
Knee Osteoarthritis (Knee OA)
Randomized Controlled Study Evaluating Genicular Artery Embolization Against Intra-Articular Corticosteroid Knee Injection for Osteoarthritic Knee Pain
Multi-center, prospective, randomized trial of GAE using Nexsphere-F against steroid injection
- Trial name
- RESORB (NCT06872567)
- Testing
- genicular artery embolization, Corticosteroid Injection
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- North American Science Associates Ltd.
Knee Osteoarthritis
Femoral Cartilage Thickness in Knee Osteoarthritis
The aim of the study to investigate the relationship between femoral cartilage thickness in Ultrasonographic evaluation and inflammatory parameters, pain severity and functionality in participants with Knee Osteoarthritis
- Trial name
- NCT05456711
- Testing
- ultrasonographic measurement for femoral cartilage thickness VAS for pain severity WOMAC for functionality
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Knee Osteoarthritis
Pulsed Radiofrequency Therapy vs Canal Adductor Blockade in Knee Osteoarthritis
This study is intended to prove the efficacy and safety of ultrasound-guided pulsed radiofrequency therapy on adductor canal nerves by patients with Knee osteoarthritis.
- Trial name
- NCT05962463
- Testing
- Canal adductor blockade, Canal adductor pulsed radio-frequency therapy
- Where
- Slovenia
- Volunteers
- 128 people
- Sponsor
- University Medical Centre Ljubljana
Osteo Arthritis Knee
Self-Administered Transcranial Direct Current Stimulation for Pain in Older Adults With Knee Osteoarthritis
The purpose of this study is to assess the feasibility, acceptability, and efficacy of self-administered transcranial direct current stimulation (tDCS) in older adults with knee osteoarthritis (OA)
- Trial name
- NCT04016272
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Florida State University
Osteoarthritis
A Study to Evaluate the Effect of Analgesics on a Walking Model of Knee Pain (0000-105)(COMPLETED)
This study will evaluate a walking model of osteoarthritis for use in testing of new therapeutic agents. The primary hypothesis is that participants treated with Naproxen or Ultracet will have lower Pain Intensity (PI) than those…
- Trial name
- NCT00772967
- Testing
- Naproxen, Ultracet
- Volunteers
- 22 people
- Sponsor
- Merck Sharp & Dohme LLC
Rehabilitation, Treatment Outcome
Effects of Exercise Therapy and Soft Brace on Knee Osteoarthritis
The primary aim of the study is to investigate the effects of supervised exercise therapy and education on the immediate response to using a soft knee brace in patients with knee osteoarthritis (OA).
- Conditions
- Rehabilitation, Treatment Outcome, Pain, Knee Brace
- Trial name
- NCT03949400
- Testing
- Exercise therapy and education.
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University College of Northern Denmark
Degenerative Joint Disease of Knee, Osteoarthritis
A Randomized Controlled Trial for Partial Knee Arthroplasty
This is a prospective, multi-center, two-arm, randomized, controlled post-market study to evaluate and compare the clinical accuracy of component placement in robotic-assisted UKA and that of traditional methods.
- Conditions
- Degenerative Joint Disease of Knee, Osteoarthritis, Traumatic Arthritis, Varus Deformity
- Trial name
- NCT05037734
- Testing
- Persona Partial Knee System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Osteoarthritis, Chronic Pain Management
The Beat Pain Better Trial
The Beat Pain Better study examines strategies to increase the reach of evidence-based interventions for persons with osteoarthritis (OA) in communities that experience disparities.
- Trial name
- NCT06932887
- Testing
- Text Messaging, Motivational Messaging, Physical Activity Counseling and Self-Directed Walk with Ease
- Where
- 3 sites in United States
- Volunteers
- 346 people
- Sponsor
- University of Utah
Osteoarthritis of Knee, Healthy Participants
Evaluation of Muscle Oxygenation and Recovery Dynamics in Individuals With Knee Osteoarthritis
Knee osteoarthritis (OA) is a degenerative joint disease characterized by pain, muscle weakness, and functional limitations that significantly affect lower limb muscle performance.
- Trial name
- NCT07471204
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Exercise Training, Osteoarthritis, Knee
Core Stabilization Exercises in Patients with Knee Osteoarthritis
Exercise plays a key role in the treatment of knee osteoarthritis, but there is no clear evidence on which type of exercise is most effective.
- Conditions
- Exercise Training, Osteoarthritis, Knee, Core Stability, Muscle Thickness of the Quadriceps Femoris
- Trial name
- NCT06621784
- Testing
- Core stabilization exercises, Classical exercise therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Knee Osteoarthritis, Chronic Pain
Arthritis Ease Study
The goal of this clinical trial is to test using a pain and anxiety reduction phone application in older adults with knee osteoarthritis and chronic pain. The main questions it seeks to answer are: 1.
- Conditions
- Knee Osteoarthritis, Chronic Pain, Kinesiophobia
- Trial name
- NCT05721352
- Testing
- Virtual Reality Nature scene plus heart rate variability biofeedback phone application
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Arizona State University
Osteoarthritis, Knee
Does Electrocautery Increase Postoperative Pain in Primary Total Knee Arthroplasty
Total knee arthroplasty (TKA) is a successful treatment for end-stage osteoarthritis of the knee. The main advantages of TKA are to relieve the pain of the knee, improve the knee function, restore lower limb alignment, and…
- Trial name
- NCT06239038
- Testing
- total knee arthroplasty
- Where
- Thailand
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Police General Hospital, Thailand
Osteoarthritis of the Knee, Coagulopathy
Trial to See if Topical Pennsaid for Knee Pain Affects Coagulation Values in Patients Who Are Also Taking Anticoagulants
The purpose of this study is to see if using a topical nonsteroidal antiinflammatory drug (Pennsaid) to treat osteoarthritis knee pain will affect coagulation values in patients who are also taking anticoagulant or antithrombotic…
- Trial name
- ATCCTCP-1 (NCT01511939)
- Testing
- Pennsaid
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Nathan Wei, MD, FACP, FACR:
Osteoarthritis
Tanezumab in Osteoarthritis of the Hip or Knee (2)
Test the efficacy and safety of 2 doses of tanezumab compared with naproxen and placebo in patients with osteoarthritis
- Trial name
- NCT00863304
- Testing
- tanezumab 10 mg, tanezumab 5 mg, naproxen
- Where
- 95 sites in United States
- Volunteers
- 849 people
- Sponsor
- Pfizer
Knee Osteoarthritis (OA)
Effects of Core Stabilization Exercises Versus Foot-Ankle Strengthening Program in Patients With Knee Osteoarthritis.
Knee osteoarthritis (OA) is also known as degenerative joint disease, is typically the result of wear and tear and progressive loss of articular cartilage. It is most common in the elder population.
- Trial name
- NCT06658249
- Testing
- Core Stabilization Exercises with Foot-Ankle Strengthening Program, Foot-Ankle Strengthening Program
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Osteoarthritis
Transcatheter Arterial Micro-Embolization (TAME) Using Nexsphere-F in Patients With Chronic Pain in Elbow or Wrist
In patients with chronic elbow or wrist pain, the pain is controlled by conventional conservative therapy The pain reduction effect of Nexsphere-F embolization in patients who need additional treatment It is intended to…
- Trial name
- NCT06207851
- Testing
- Transcatheter Arterial Micro-Embolization
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Next Biomedical Co., Ltd.
Pain, Postoperative, Opioid Use
Cannabidiol for Bilateral Total Knee Arthroplasty
In light of the opioid epidemic and evidence suggesting that cannabis may be opioid-sparing, we are in a unique position to conduct a novel, high-impact study that would set the stage for future RCTs examining the effects of a…
- Conditions
- Pain, Postoperative, Opioid Use, Knee Osteoarthritis
- Trial name
- NCT04749628
- Testing
- cannabidiol, Ora-sweet SF
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Hospital for Special Surgery, New York
Knee Osteoarthristis
Effect of a Topical Cetylated Fatty Acid Cream on Pain Relief in Patients With Knee Osteoarthritis
This multicenter, randomized, double-blind, placebo-controlled study is designed to evaluate the efficacy and safety of Cetilar® cream in adults with osteoarthritis-related knee pain.
- Trial name
- CETI-KNEE (NCT07745387)
- Testing
- Cetilar® Cream
- Where
- 4 sites in Georgia
- Volunteers
- 156 people
- Sponsor
- Pharmanutra S.p.a.
Osteoarthritis, Knee
Safety, Tolerability, and Efficacy of XT-150 for the Treatment of Osteoarthritic Pain
Evaluation of Safety, Tolerability, and Efficacy of XT-150, a plasmid DNA with a variant of human IL-10 transgene. XT-150 will be a single injection into the knee synovial capsule for the Treatment of Osteoarthritic Pain.
- Trial name
- NCT03477487
- Testing
- XT-150
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Xalud Therapeutics, Inc.
Osteoarthritis (OA) of the Knee, Pain
ASKC200 for Knee Osteoarthritis Pain
This is a Phase II clinical trial designed to evaluate the efficacy and safety of ASKC200 Lotion in patients with knee osteoarthritis (KOA) pain.
- Trial name
- ASKC200 (NCT07742852)
- Testing
- 5% ASKC200, 1% Diclofenac Diethylamine Emulgel, 1% ASKC200
- Where
- China
- Volunteers
- 175 people
- Sponsor
- Jiangsu Aosaikang Pharmaceutical Co., Ltd.
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