Clinical trials: Osteoarthritis Pain
Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee
Ketogenic Diet to Reduce Osteoarthritis Pain in MCI
Osteoarthritis and mild cognitive impairment are common conditions that share underlying biological processes related to metabolism and inflammation.
- Conditions
- Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee, Osteoarthritis (OA) of the Shoulder, Osteoarthritis
- Trial name
- KDROP-MCI (NCT07417891)
- Testing
- Well-formulated ketogenic diet
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Kansas Medical Center
Knee Osteoarthritis, Stochastic Resonance Therapy-Whole Body Vibration
Comparing Whole-Body Vibration vs. Balance Board Exercise for Pain, Function, and Quality of Life in Obese Adults With Knee Osteoarthritis
Background: Osteoarthritis (OA) is a joint disease commonly found in the knee. Therapeutic exercise has been known as the most common therapy to treat OA, however, therapy only focuses on reducing symptoms, not on treatment of…
- Conditions
- Knee Osteoarthritis, Stochastic Resonance Therapy-Whole Body Vibration, Obesity, Balance Board
- Trial name
- NCT07568691
- Testing
- Stochastic Resonance Therapy-Whole Body Vibration, Balance Board
- Where
- Indonesia
- Volunteers
- 44 people
- Sponsor
- Universitas Indonesia
Arthralgia, Stiffness of Unspecified Joint, Not Elsewhere Classified
Comparative Study of Turmeric Extract in Patients With Arthrosis.
The aim of this study is to test if an extract of Turmeric can alleviate symptoms of osteoarthritis in volunteers with osteoarthritis of the hip and or knee.
- Conditions
- Arthralgia, Stiffness of Unspecified Joint, Not Elsewhere Classified, Disturbance of Activity and Attention, Quality of Life
- Trial name
- NCT04500210
- Testing
- Turmeric
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kaj Winther Hansen
Osteoarthritis, Knee
Radio- KO Radiotherapy for Knee Osteoarthritis Clinical Trial
The primary aim of this study is to investigate whether low-dose radiotherapy is an effective treatment to reduce the pain of knee osteoarthritis.
- Trial name
- RADIO-KO (NCT06887829)
- Testing
- Low dose radiotherapy
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Mayo Clinic
Osteoarthritis, Pain Intensity Assessment
A Study to Evaluate 90-Day Safety of Tapentadol(CG5503) Immediate Release (IR) or Oxycodone Immediate Release in Patients With Chronic Pain
The purpose of this study is to evaluate the safety of CG5503 base Immediate Release(IR) 50 mg or 100 mg taken every 4 to 6 hours as needed over the long-term exposure of 90 days in patients who have chronic pain.
- Conditions
- Osteoarthritis, Pain Intensity Assessment, Arthralgia, Sciatica
- Trial name
- NCT00364546
- Testing
- CG 5503;tapentadol
- Volunteers
- 877 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Musculoskeletal Diseases, Osteoarthritis, Knee
Effect of Research Participation Versus Usual Clinical Treatment on Pain in Patients With Musculoskeletal Disorders
This study explores the effects on pain, function and illness perceptions, of participating in clinical research versus being treated with standard care in patients with musculoskeletal disorders.
- Conditions
- Musculoskeletal Diseases, Osteoarthritis, Knee, Illness Perceptions
- Trial name
- NCT03785561
- Testing
- participation in a health research study
- Where
- Denmark
- Volunteers
- 1,850 people
- Sponsor
- Frederiksberg University Hospital
Osteo Arthritis Knee
Self Cranial Electrical Stimulation (CES) for Pain in Older Adults With Knee Osteoarthritis (Self CES for Knee Pain)
The purpose of this study is to determine the feasibility, safety, and preliminary efficacy of a two-week self Cranial Electrical Stimulation(CES) on pain in older adults with knee osteoarthritis(OA)
- Trial name
- NCT04016259
- Testing
- Cranial Electrical Stimulation (CES)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center, Houston
Gonarthrosis
The Effect of Tail Fat Application on Joint Pain, Joint Stiffness, and Daily Living Activities in Patients With Gonarthrosis
In recent years, experimental and clinical studies conducted on sheep tail fat, a natural and easily accessible resource, have shown that bioactive components found in sheep tail fat, such as palmitic acid, stearic acid, oleic…
- Trial name
- NCT07867405
- Testing
- Sheep Tail Fat, Standard medical treatment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Inonu University
Osteoarthritis, Pain, Postoperative
Liposomal Bupivacaine Versus Standard Bupivacaine Plus Dexamethasone in Quadriceps Sparing Femoral Nerve Block and Wound Infiltration for Total Knee Arthroplasty
The purpose of this study is to compare the efficacy and duration of pain relief after total knee arthroplasty provided by a single injection of liposomal bupivacaine (EXPAREL®) versus standard bupivacaine with an adjuvant…
- Trial name
- NCT02624856
- Testing
- Liposomal bupivacaine, Bupivacaine plus dexamethasone
- Where
- United States
- Sponsor
- Albany Medical College
Knee Osteoarthritis, Osteo Arthritis Knee
Effectiveness of Physical Therapy in Stem Cell Transplant Recipients for Knee Osteoarthritis
Knee osteoarthritis has been considered as 11th highest contributor factor to nonfatal burdens in the world. It is considered one of the most common degenerative diseases of synovial joint and major cause of muscle impairment…
- Conditions
- Knee Osteoarthritis, Osteo Arthritis Knee, OA Knee
- Trial name
- NCT05959902
- Testing
- Forward Walking, Physiotherapy Exercises
- Where
- 2 sites in Pakistan
- Volunteers
- 48 people
- Sponsor
- Dow University of Health Sciences
Osteoarthritis, Knee, Knee Osteoarthritis
AP-003-C Study to Confirm the Efficacy of Ampion™ in Adults With Pain Due to Severe Osteoarthritis of the Knee
This is a phase 3 randomized study to confirm the efficacy of an intra-articular injection of Ampion™ in adults with pain due to severe osteoarthritis of the knee.
- Conditions
- Osteoarthritis, Knee, Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic
- Trial name
- NCT03182686
- Testing
- 4 mL injection of Ampion
- Where
- 13 sites in United States
- Volunteers
- 168 people
- Sponsor
- Ampio Pharmaceuticals. Inc.
Osteoarthritis, Knee, Osteoarthritis
Low Intensity Pulsed Ultrasound Versus High Intensity Continuous Ultrasound Therapy in Knee Osteoarthritis
To compare the effects of low intensity pulsed ultrasound with high intensity continuous ultrasound in knee osteoarthritis
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Rheumatic Diseases, Musculoskeletal Diseases
- Trial name
- NCT04406337
- Testing
- Low intensity pulsed ultrasound, High intensity continuous ultrasound
- Where
- Burma
- Volunteers
- 86 people
- Sponsor
- Ministry of Health and Sports, Myanmar
Acute Pain (Flare) Associated With Osteoarthritis (OA) of the Knee
Efficacy and Safety of Impracor (Ketoprofen 10% Cream) Compared With Placebo in the Treatment of Acute Pain (Flare) Associated With Osteoarthritis of the Knee
The primary objective of the study is to assess analgesic efficacy of Impracor (Ketoprofen 10% Cream) compared to placebo for acute pain associated with OA flare of the knee.
- Trial name
- NCT01890902
- Testing
- Ketoprofen 10% Cream
- Sponsor
- Imprimis Pharmaceuticals, Inc.
Osteoarthritis Hand
Efficacy of Surgical Joint Denervation in Painful Digital Osteoarthritis
Digital osteoarthritis is the second localization of symptomatic osteoarthritis, after the knee. Its cardinal symptoms are particularly intense pain and functional impairment in the case of the erosive form.
- Trial name
- DECAD (NCT05378841)
- Testing
- Surgical Denervation
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Knee Osteoarthritis
Clinic-based and Tele-monitored Home-based Intervention in Patients With Knee OA
This study assessed and compared the effects of clinic-based and telemonitored home-based interventions on pain intensity, function and quality of life in patients with knee osteoarthritis (KOA).
- Trial name
- CB&HMInKOA (NCT05832866)
- Testing
- Clinical Based Isometric contraction strengthening Exercises using Thera band, Telemonitored Home based Isometric Cntraction strengthening exercises using Thera band
- Where
- Nigeria
- Volunteers
- 42 people
- Sponsor
- Obafemi Awolowo University
Osteoarthritis
The Safety and Efficacy of XytriX (Umbilical Cord-Derived Mesenchymal Stem Cells) in the Treatment of Knee Osteoarthritis
This study aims to study the safety and efficacy of XytriX, an umbilical cord-derived stem cell product, in the treatment of Grade I-IV knee osteoarthritis.
- Trial name
- NCT07487766
- Testing
- Mesenchymal Stem Cell Injection
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- TricelX Inc.
Osteoarthritis, Knee
Efficacy and Safety of Single, Low-dose Dexamethasone in Patients After Total Knee Arthroplasty
This study was conducted to determine the efficacy of an additional preemptive, single, low-dose dexamethasone in terms of incidence and severity of postoperative nausea/vomiting (PONV), pain level, and the safety in terms of…
- Trial name
- NCT01612702
- Testing
- Dexamethasone
- Where
- South Korea
- Volunteers
- 291 people
- Sponsor
- Tae Kyun Kim
Osteoarthritis, Knee
Genicular Radiofrequency Ablation Following Total Knee Arthroplasty
Currently, nearly 1 million total knee arthroplasties (TKA) are performed yearly in the United States. Three million are projected to be performed in 2040.
- Trial name
- GRATKA (NCT05283889)
- Testing
- Genicular Radiofrequency Ablation
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University of Calgary
Knee Osteoarthritis
Prospective Evaluation of Subchondroplasty in Advanced Knee Osteoarthritis.
The goal of this observational study is to evaluate the technique of subchondroplasty in patients with advanced knee osteoarthritis.
- Trial name
- NCT06027697
- Testing
- AccuFill® Porous Bone Substitute Material (BSM)
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Clinique Paris-Bercy
Arthritis, Osteoarthritis
A Study of the Effect on Pain Control of Treatment With Fentanyl, Administered Through the Skin, in Patients With Rheumatoid Arthritis or Osteoarthritis
The purpose of this study is to assess the degree of pain control achieved by treatment with fentanyl, administered via adhesive patches applied to the skin ('transdermal system") in patients with rheumatoid arthritis or…
- Conditions
- Arthritis, Osteoarthritis, Rheumatoid Arthritis
- Trial name
- NCT00524160
- Testing
- Fentanyl transdermal patch
- Volunteers
- 264 people
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
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