Clinical trials: Osteoarthritis Thumb
Thumb Osteoarthritis
Effectiveness of Proprioceptive Exercises Program in Patients With Carpometacarpal Joint Osteoarthritis
Objective: To establish the effectiveness of a proprioceptive training program as a complementary therapy for a traditional protocol in position control, pain intensity, upper limb function and occupation performance for patients…
- Trial name
- NCT04777526
- Testing
- Proprioception exercises, Joint protection program, Thumb orthosis
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- University of Malaga
Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis
Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy
The goal of this clinical trial is to learn if the surgical method with total joint arthroplasty, (TOUCH joint prosthesis), is as good as or better than the traditional surgical method, trapezectomy, to treat thumb base joint…
- Conditions
- Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis, Carpometacarpal (CMC) Joint Arthritis, Basal Thumb Osteoartrithis
- Trial name
- BASTION (NCT07569549)
- Testing
- Implantation of trapeziometacarpal prosthesis, Trapeziectomy with Capsuloplasty
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Uppsala University
Thumb Carpometacarpal Joint Osteoarthritis
Platelet-rich Plasma for Thumb Carpometacarpal Joint Osteoarthritis
The purpose of this study is to investigate a case series of patients treated with Platelet-rich plasma for thumb carpometacarpal joint osteoarthritis.
- Trial name
- NCT04886349
- Testing
- Platelet-rich plasma
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Mayo Clinic
Osteoarthritis Thumb
Intra-articular Allocetra in Osteoarthritis of the 1st Carpo-metacarpal Joint
This study is a single center trial to assess the safety and efficacy of intra-articular administration of Allocetra to patients with 1st CMC thumb joint osteoarthritis (OA).
- Trial name
- NCT06459063
- Testing
- Allocetra - Safety run-in phase, Allocetra - Randomization phase
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- Kaplan Medical Center
Rhizarthrosis
Rhizarthrosis Study
Rhizarthrosis is the wear of the thumb saddle joint. It is a very common disease affecting up to 25% of postmenopausal women. There are currently various conservative and surgical methods available for treatment.
- Trial name
- RHI (NCT04587570)
- Testing
- Infiltration with PRP, Infiltration with Fat, Infiltration with PRP and Fat
- Where
- Austria
- Volunteers
- 131 people
- Sponsor
- Medical University of Graz
Osteoarthritis Thumb
Intraarticular Steroids, Saline and Occupational Therapy in People With CMC1 Osteoarthritis
A placebo-controlled randomized controlled trial exploring the effect of intraarticular steroids, saline or an occupational therapy intervention in inflammatory carpometacarpal-1 osteoarthritis
- Trial name
- PICASSO (NCT06084364)
- Testing
- Injection of triamcinolone acetonide into the CMC-1 joint, Multimodal Occupational therapy for CMC-1 joint OA
- Where
- 6 sites in Norway
- Volunteers
- 354 people
- Sponsor
- Diakonhjemmet Hospital
Osteoarthritis, Thumb Arthritis
Predictive Model for 1-Year Pain and Function Outcomes After Thumb Joint Surgery in Osteoarthritic Patients
This study aims to develop a predictive model to help doctors better understand expected outcomes one year after thumb joint surgery for osteoarthritis.
- Conditions
- Osteoarthritis, Thumb Arthritis, Arthroplasty of the MCP Joint
- Trial name
- NCT06740851
- Testing
- Touch® Trapeziometacarpal Joint Arthroplasty
- Where
- Switzerland
- Volunteers
- 330 people
- Sponsor
- Michael Oyewale
Osteoarthritis Thumb, Joint Diseases
Radial Nerve Mobilization in Hand Thumb Osteoarthritis Patients
Hand-thumb carpometacarpal (1st CMC) joint osteoarthritis is defined as the degeneration occurring between the articular surfaces of the 1st metacarpal bone and the trapezium bone.
- Conditions
- Osteoarthritis Thumb, Joint Diseases, Radial Neuropathy
- Trial name
- NCT05650970
- Testing
- routine therapy, radial nerve mobilization exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Gazi University
Osteoarthritis Thumb
Arthroscopic Debridement vs Arthroscopic Hemi-Trapeziectomy on Patients With Thumb Carpometacarpal Joint Osteoarthritis
Patients with thumb carpometacarpal joint osteoarthritis usually suffer from pain, joint enlargement, inflammation, deformity and loss of function.
- Trial name
- NCT04217928
- Testing
- Arthroscopic Debridement, Arthroscopic Hemi-Trapeziectomy with Mini TightRope
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Osteoarthritis
Use of Autologous Adipose-Derived Stromal Vascular Fraction To Treat Osteoarthritis of Hip, Knee, Ankle, and Thumb Joints
This study will examine the safety and efficacy of autologous adipose-derived stromal vascular fraction (SVF) cells for treatment of hip, knee and thumb osteoarthritis (OA); monitoring adverse events and measuring pain, function…
- Trial name
- NCT03166410
- Testing
- Cell injection
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Texas Plastic Surgery
Lactobacillus Plantarum
Lactobacillus Plantarum: Thumb Osteoarthritis Following Orange Peeling
Case Description osteoarthritis + amputation of the distal phalanx of the right thumb caused by Lactobacillus plantarum after an orange peel.
- Trial name
- NCT02884336
- Testing
- No intervention
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Trapeziometacarpal Osteoarthritis, Thumb Carpometacarpal Osteoarthritis
Surgical Treatment for Trapeziometacarpal Osteoarthritis Eaton & Glickel Stage 4
Trapeziometacarpal osteoarthritis is a common cause of pain and loss of hand function in postmenopausal women. Many surgical treatments have been described and recent literature has show that the relatively simple trapeziectomy…
- Trial name
- NCT02204995
- Testing
- Trapeziectomy with LRTI, Trapeziectomy
- Where
- Netherlands
- Volunteers
- 62 people
- Sponsor
- Isala
Osteoarthritis Thumb
Influence of the Radiological Stage on the Efficiency of Viscosupplementation in Basal Thumb Arthritis
The rhizarthrose is the most frequent affection of the hand at the age fifty and beyond. For the moderate forms of the disease, the majority of the studies recommend the recourse to the viscosupplement because of its efficiency…
- Trial name
- INSTINCT (NCT03622736)
- Where
- France
- Volunteers
- 122 people
- Sponsor
- Labrha
Thumb Osteoarthritis
Proprioceptive Thumb Exercises Program in Patients With Carpometacarpal Joint Osteoarthritis
Osteoarthritis (OA) is a chronic and prevalent joint disorder with great impact on quality of life and high economic burden. Although a number of conservative therapies have proven to be effective for the management of hand OA…
- Trial name
- thumb (NCT04738201)
- Testing
- Proprioceptive thumb exercises.
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- University of Malaga
Osteoarthritis
A Study of Hyaluronan for the Treatment of Osteoarthritis in the Thumb
Hyaluronan is a man-made preparation of a protein complex that occurs naturally in joints and that is often low in people with osteoarthritis.
- Trial name
- NCT00398866
- Testing
- Synvisc (Hylan G-F20; hyaluronan injection), Bupivicaine (local anesthesia injection), Kenalog (triamcinolone; corticosteroid injection)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Hospital for Special Surgery, New York
Osteoarthritis of the Hand
AP-011 Study to Evaluate the Safety of a Single Intra-articular Injection of Ampion™ for Arthritis of the Basal Thumb Joint
This study will evaluate the safety of an intra-articular injection of AMPION™ in adults with pain due to osteoarthritis of the basal thumb joint.
- Trial name
- NCT02762760
- Testing
- AMPION™, Saline
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ampio Pharmaceuticals. Inc.
Osteoarthritis Thumb, Joint Diseases
Touch on One Thumb, RSI on the Other Thumb: Which Surgery Shows Better Results
The study aims to determine whether CMC I arthroplasty using a Touch® implant results in higher patient satisfaction compared to RSI arthroplasty in the medium-term in patients with primary thumb osteoarthritis.
- Conditions
- Osteoarthritis Thumb, Joint Diseases, Musculoskeletal Diseases or Conditions, Osteoarthritis
- Trial name
- NCT05849506
- Testing
- Touch® Prosthesis
- Where
- Switzerland
- Volunteers
- 14 people
- Sponsor
- Schulthess Klinik
Trapeziometacarpal Osteoarthritis
Thumb Muscle Activation During Different Activities of Daily Living in Thumb Base Osteoarthritis and Healthy Controls
The aim of this study is to investigate whether there are differences in muscle activation of the first dorsal interosseous (FDI) and the abductor pollicis longus (APL) between individuals with and without thumb…
- Trial name
- NCT07866703
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Base-of-thumb Osteoarthritis
Efficacy of an Intra-articular Injection of Botulinum Toxin A Associated With Splinting for Base-of-thumb Osteoarthritis
The primary purpose of this study is to determine whether a single ultrasound-guided intra-articular injection of botulinum toxin A associated to splinting is effective in reducing pain at 3 months in base-of-thumb osteoarthritis.
- Trial name
- RHIBOT (NCT03187626)
- Testing
- botulinum toxin A, saline
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteoarthritis
Improvement of Implant Survival in Total Joint Arthroplasty of the Trapeziometacarpal Joint
The study evaluates implant survival in total joint arthroplasty of the Trapeziometacarpal (TMC) joint by monitoring the survival of different implant types using radiostereometry (RSA) evaluation of the implants.
- Trial name
- NCT01554748
- Testing
- Total joint arthroplasty
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Regional Hospital Holstebro