Clinical trials: Osteopenia, Osteoporosis
Osteopenia
Effect of Whole-Body Vibration on Plasma Sclerostin Level
The aim of this study is to investigate effect of whole-body vibration on plasma sclerostin level in healthy young adult women. Fifteen healthy young adult women are planned to include in this study.
- Trial name
- WBV-SCL (NCT01310335)
- Testing
- whole-body vibration (WBV)
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Low Bone Density, Osteopenia
A Taiwan Isoflavone Multicenter Study (TIMS)
Consumption of soy-based foods is associated with a number of health benefits, including lower risk of cardiovascular disease, breast and prostate cancer, attenuated menopausal symptoms and prevention of bone loss with age.
- Trial name
- NCT00262184
- Testing
- Soy Isoflavone
- Where
- 3 sites in Taiwan
- Volunteers
- 420 people
- Sponsor
- National Health Research Institutes, Taiwan
Osteoporosis, Chronic Respiratory Disease
Collaborative Care With Smart Health Management Program for Patients With Chronic Illness
This study verifies efficacy of collaborative care with Smart Health Management Program developed for patients with chronic illness.
- Conditions
- Osteoporosis, Chronic Respiratory Disease, Arthritis, Osteopenia
- Trial name
- NCT03294057
- Testing
- Tele-coaching programs, ICT programs, A book about chronic disease
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Seoul National University Hospital
Osteoporosis, Bone Loss, Age Related
Osteoporosis Choice Decision Aid for Use of Bisphosphonates in Postmenopausal Women
To develop a decision aid to support the decision to use (or not use) bisphosphonates in postmenopausal women at risk for osteoporotic fractures, and to assess the impact of the decision aid on start and six month adherence to…
- Conditions
- Osteoporosis, Bone Loss, Age Related, Postmenopausal Bone Loss, Postmenopausal Osteoporosis
- Trial name
- NCT00578981
- Testing
- Osteoporosis Choice Decision Aid
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Osteoporosis, Osteopenia, Bone Loss
Protocol Optimization in CT for the Quantification of BMD
Bone mineral density is an important measurement to detect osteoporosis. The goal of this clinical trial is to compare bone mineral density measurements in CT examinations and DXA scans.
- Trial name
- NCT06305156
- Testing
- Bone Mineral Density quantification
- Where
- Switzerland
- Volunteers
- 167 people
- Sponsor
- Hatem Alkadhi
Osteopenia, Osteoporosis
Bone Response to Soy Isoflavones in Women
This study will provide valuable data on whether soy isoflavones impact bone loss in postmenopausal women. The study will help clarify potential mechanisms and contribute to our understanding of isoflavones as an alternative to…
- Trial name
- SIRBL (NCT00043745)
- Testing
- Soy isoflavones, Extract tablets
- Where
- 2 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Osteopenia, Osteoporosis
Once Weekly Parathyroid Hormone for Osteoporosis
Daily parathyroid hormone (PTH) is approved by the FDA for the treatment of osteoporosis. This study will evaluate the safety and effectiveness of PTH when given once a week.
- Trial name
- NCT00065637
- Testing
- Teriparatide
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco
Osteopenia, Osteoporosis
Effects of Physical Exercise on Postmenopausal Risk Factors in Women With Osteopenia
Menopause usually have a serious impact on a woman's life, associated with negative consequences for health and quality of life.
- Trial name
- ACTLIFE (NCT03959995)
- Testing
- High Intensity Resistance (HIT-RT) and Endurance exercise (HIIT), Wellness
- Where
- Germany
- Volunteers
- 27 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Hepatitis C, Chronic, Liver Diseases
Influence of Antiviral Therapy on Bone Mineral Density and Metabolism in Patients With Chronic Hepatitis C
One single study has suggested that bone mineral density (BMD) is reduced in patients with non-cirrhotic chronic viral hepatitis C. Antiviral combination therapy with standard interferon and ribavirin may further decrease BMD.
- Conditions
- Hepatitis C, Chronic, Liver Diseases, Virus Diseases
- Trial name
- NCT00948220
- Testing
- peginterferon alfa-2a and ribavirin
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- University of Ulm
Osteoporosis, Osteopenia
The Effect of Exercise in Postmenopausal Women with Low Bone Density
This clinical trial aims to evaluate the effects of a 12 month gym- and home-based exercise program on bone density and falls risk factors in postmenopausal women with low bone density.
- Trial name
- NCT00643331
- Testing
- Exercise
- Where
- Australia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Osteoporosis
Investigation of Q Angle in Osteoporosis Patients
Osteoporosis (OP) is a bone disease characterized by reduced bone density and deterioration of bone tissue, leading to an increased risk of fractures.
- Trial name
- NCT06475794
- Testing
- Patients with osteoporosis group, Patients with osteoarthritis group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Firat University
Osteopenia, Osteoporosis
A Study of Changes in Bone Mineral Density as a Function of Consuming Two Different Forms of Calcium Carbonate
The purpose of this study is to determine whether consuming calcium carbonate that has been micronized is more effective than the traditional form of calcium carbonate in maintaining or increasing bone mineral density in people…
- Trial name
- NCT01857154
- Testing
- Micronized Calcium Carbonate, Non-Micronized Calcium Carbonate, Vitamin D3
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Integrative Health Technologies, Inc.
Crohn's Disease, Nephrotic Syndrome
Glucocorticoid-induced Osteopenia in Children
The purpose of this study is to characterize the skeletal deficits and risk factors for impaired skeletal development in children requiring glucocorticoid therapy.
- Trial name
- NCT00289328
- Where
- United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Gaucher Disease
Genzyme Osteopenia/Osteoporosis Study
Gaucher disease is a most common genetic metabolic disease characterized by low platelet number, liver and spleen enlargement and various forms of bone diseases including low bone mineral density leading to brittle bones.
- Trial name
- NCT02785744
- Testing
- Gaucher disease DNA mutation analysis
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- NYU Langone Health
Breast Cancer, Osteoporosis
Zoledronate, Calcium, and Vitamin D in Preventing Bone Loss in Women Receiving Adjuvant Chemotherapy for Breast Cancer
RATIONALE: Zoledronate plus calcium and vitamin D may prevent bone loss in patients receiving adjuvant chemotherapy for breast cancer. It is not yet known which regimen is more effective in preventing bone loss.
- Trial name
- NCT00022087
- Testing
- calcium salts, cholecalciferol, zoledronic acid
- Where
- 107 sites in United States
- Volunteers
- 439 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Osteoporosis, Osteopenia
Investigating the Effect of Standardized Olive Extract on Bone Turnover Markers in Postmenopausal Women
The purpose of this study is to determine whether the intake of a daily dosage of standardized olive extract provides any protection against bone loss.
- Trial name
- NCT00789425
- Testing
- Standardized Extract of Olive Polyphenols
- Where
- Poland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- BioActor
Osteopenia, Osteoporosis
Safety and Efficacy of Multiple Dosing Regimens of BPS804 in Post Menopausal Women With Low Bone Mineral Density
This study is designed to provide information on the safety, tolerability, pharmacokinetics (PK) and bone biomarker response following multiple BPS804 administration in multiple dosing regimens.
- Trial name
- NCT01406548
- Testing
- BPS804 20mg/Kg
- Where
- 5 sites in United States
- Volunteers
- 44 people
- Sponsor
- Ultragenyx Pharmaceutical Inc
Bone Density, Osteopenia
Evaluation of Bone Mineral Density Indications and Outcomes in Female Adolescents: Implications for Early Detection of Osteopenia/Osteoporosis and Gynecologic Practice
This retrospective study evaluates bone mineral density (BMD) measurements obtained by dual-energy X-ray absorptiometry (DEXA) in adolescent girls aged 12 to 21 years at a tertiary care center.
- Conditions
- Bone Density, Osteopenia, Amenorrhea, Primary Amenorrhea
- Trial name
- TEEN-BMD (NCT07164248)
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Bagcilar Training and Research Hospital
Type 1 Diabetes, Type 2 Diabetes
Abnormal Structure and Bone Density in Diabetes
Assumptions and Objectives: The working hypotheses are: 1 - subjects with type 1 diabetes and / or type 2, compared to subjects without diabetes are at risk for osteopenia and / or abnormal bone structure the foot (calcaneus and…
- Trial name
- NCT01094899
- Testing
- Radiography, Urine and Blood sampling, Echography
- Where
- France
- Volunteers
- 79 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Bone Demineralization
Alendronate for Prevention of AntiRetroviral Therapy-associated Bone Loss
Antiretroviral therapy (ART) initiation is associated with a significant loss of bone mineral density (BMD), characterised by increases in bone turnover, which is largely limited to the first 48 weeks of therapy.
- Trial name
- APART (NCT02322099)
- Testing
- Alendronate, calcium carbonate and colecalciferol, Tenofovir disoproxil
- Where
- 2 sites in Ireland
- Volunteers
- 53 people
- Sponsor
- University College Dublin