Clinical trials: Osteopenia
Periimplantitis, Marginal Bone Loss
A Study of the Crestal Bone Loss Around Bone Level Versus Tissue Level Implants in Non-compliant Patients With Healthy or Reduced Periodontium After 5-8 Years in Function
The goal is to evaluate, after 5 to 8 years, the marginal bone loss around tissue-level implants and bone-level implants in patients who have not followed the maintenance program.
- Trial name
- NCT04942808
- Testing
- Periapical radiographs
- Where
- Lebanon
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Osteopenia, Prematurity
Proton Pump Inhibitor Therapy and Bone Density in Premature Infants
Previous research studies have shown that there may be a connection between proton pump inhibitor therapies and hip fracture in adults(1).
- Trial name
- PPI (NCT00888017)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Utah
Marginal Bone Loss
Efficacy of Implant Surface Characteristics in Patients With History of Periodontitis
The aim of the study is to evaluate in patients with history of periodontitis the clinical, microbiological and radiological outcomes of implants with a modified implant design consisting on a machined surface in the coronal…
- Trial name
- NCT05010382
- Testing
- Implant placement surgery
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
Bone Loss in Jaw, Dental Implant Failure Nos
Marginal Bone Loss Around Mandibular Implant-retaining Overdentures and Implant Supported Fixed Hybrid Prosthesis
Few if any studies have compared marginal bone loss (MBL) around implant-retaining overdentures (2 implants with locators) versus implant supported fixed hybrid prosthesis (over 4 implants) in the mandible.
- Conditions
- Bone Loss in Jaw, Dental Implant Failure Nos, Dental Implant Failed
- Trial name
- NCT06488599
- Testing
- Peri-apical radiographs on the implants
- Where
- Lebanon
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Periodontal Diseases, Periodontal Pocket
Comparison of Gingival Flap Procedure Using Conventional Surgical Loupes vs. Videoscope for Visualization
This study is being performed to compare different methods of visualization during routine gum surgery. The gum surgery is standard of care.
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontitis, Periodontal Inflammation
- Trial name
- NCT05932017
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Alveolar Bone Resorption, Alveolar Ridge Trauma
Vertical Ridge Augmentation Strategies
Guided Bone Regeneration (GBR) is an invaluable and beneficial surgical technique adopted when there is the need to augment an alveolar atrophy.
- Conditions
- Alveolar Bone Resorption, Alveolar Ridge Trauma, Alveolar Bone Loss, Complication of Surgical Procedure
- Trial name
- VARGAS (NCT06242782)
- Testing
- VRA + d-PTFE membrane, VRA + e-PTFE membrane, VRA + customised Ti-mesh
- Volunteers
- 148 people
- Sponsor
- University College, London
Marginal Bone Loss
Assessment of Marginal Bone Loss and Anterior Implant Stability in Immediate Versus Early Implant Placement
This study aims to determine the differences in implant stability and measurement of bone loss near implants between two different healing approaches used for teeth replacement in the front part of the upper jaw.
- Trial name
- NCT06985511
- Testing
- Immediate implant placement, Early implant placement
- Where
- Lebanon
- Volunteers
- 12 people
- Sponsor
- Yasser Ahmed
Osteoporosis
Study Evaluating Changes In Bone Mineral Density (BMD), And Safety Of Rhbmp-2/CPM In Subjects With Decreased BMD
The main purpose of this study is to assess whether a locally-administered rhBMP-2/CPM injection can rapidly increase bone mass in subjects at high risk for osteoporotic fractures of the hip.
- Trial name
- NCT00752557
- Testing
- rhBMP-2/CPM injection and bisphosphonates, calcium, and vitamin D (oral bisphosphonate therapy), bisphosphonates, calcium, and vitamin D
- Where
- 35 sites in United States, Belgium and 2 more
- Volunteers
- 50 people
- Sponsor
- Pfizer
Bone Atrophy, Alveolar
All-on-Four Implants With Ultrasonic
The objective of this observational study is the radiographic evaluation of marginal bone remodeling after surgical implant insertion in an immediate loading all-on-four technique with trans-sinusal titanium implants, correlating…
- Trial name
- Nobelsinus (NCT03357692)
- Testing
- all on four implant rehabilitation
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Dental Implants, Immediate Dental Implant Loading
Immediate Restoration of a New Implant With High Primary Stability
The main objective of this scientific study is to evaluate the short-term (1-year) survival and success rates of dental implants restored immediately compared to implants restored after a three-month healing period.
- Trial name
- CT (NCT07498556)
- Testing
- Control Group, Test group - Implant restoration with a temporary crown
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Universidade do Porto
Bone Loss
A Prospective, Multicentre, Open-label Randomised Controlled Study to Investigate the Effectiveness of Pamidronate in the Prevention of Bone Loss in de Novo Renal Transplant Patients.
The purpose of the study was to evaluate the effect of Pamidronate on bone mineral density loss and fracture rates up to 2 years, in post renal-transplant subjects on a Ciclosporin A and glucocorticoid based immunosuppressive…
- Trial name
- SMART (NCT00738257)
- Testing
- Pamidronate
- Where
- United Kingdom
- Volunteers
- 126 people
- Sponsor
- Novartis Pharmaceuticals
Tooth Loss, Edentulism
PMCF Study on the Effectiveness and Safety of BIODENTOSS® and DWC® Dental Implants and Superstructures
This prospective, single-center, interventional post-market clinical follow-up (PMCF) study aims to evaluate the early-term (24 months post-implantation) safety and efficacy of CE-marked BIODENTOSS® and DWC ® Dental Implants and…
- Trial name
- NCT07633665
- Testing
- BIODENTOSS Bone-Level Dental Implant and Superstructures, DWC Bone-Level Dental Implant and Superstructures
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Değirmenci Otomotiv ve Metal Endüstri A.Ş.
Healing Wound, Alveolar; Wound
Ultrasound for Socket Healing Evaluation
The design is a single blinded, dual comparative study of ultrasound versus micro-CT/LASCA in one study group. Up to a total of 140 subjects registered will be recruited.
- Conditions
- Healing Wound, Alveolar; Wound, Alveolar Bone Loss, Image
- Trial name
- NCT06017193
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Bone Loss, Missing Teeth
The Use of Bio-Oss Collagen for Sinus Augmentation Using the Transcrestal Approach.
To assess vertical bone height gain with Geistlich Bio-Oss Collagen used in conjunction with simultaneous implant installation in transcrestal approach sinus augmentation.
- Trial name
- NCT04581304
- Testing
- Geistlich Bio-Oss® Collagen, Geistlich Bio-Oss® Granules
- Where
- Israel
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Dental Implant, Bone Loss
Ridge Augmentation Using Allograft Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor
This study will compare two techniques to achieve increase in ridge dimensions as a preparation for dental implants using a resorbable barrier membrane and bone particulate allogenic graft hydrated with saline or a growth factor…
- Trial name
- NCT04954664
- Testing
- Allograft particles hydrated with rhPDGF, Allograft particles hydrated in a conventional way with saline.
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Periodontal Bone Loss
The Use of Chlorhexidine Gel Following EDTA Root Surface Etching as an Adjunctive to Open Flap Debridement in Treating Intra-Bony Defects
SUMMARY Chronic periodontitis is regarded as an inflammatory disease that affects the supporting tissues of teeth which could lead to bone destruction.
- Trial name
- NCT05170932
- Testing
- CHX gel 2 % + 24% EDTA
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Periodontitis, Dental Caries
Using Combination of Synthetic Bone Substitutes During Extractions
The study was designed to assess the effectiveness of conservation ridge preservation (horizontal and vertical dimension) after tooth extraction with and without combination of bone substitutes based on synthetic (calcium sulfate…
- Conditions
- Periodontitis, Dental Caries, Alveolar Bone Losses
- Trial name
- NCT01503593
- Testing
- Calcium Phosphate, Calcium Sulphate
- Volunteers
- 40 people
- Sponsor
- Rambam Health Care Campus
Rheumatoid Arthritis, Osteoporosis
A Study on the Prevention and Treatment of GIOP With Eldecalcitol
The study will be a multi-center, randomized, open label, parallel trial conducted in rheumatoid arthritis patients treated with glucocorticoids.
- Conditions
- Rheumatoid Arthritis, Osteoporosis, Osteopenia
- Trial name
- ELEGANT (NCT06385093)
- Testing
- Eldecalcitol capsules, Alfacalcidol tablets, Calcium carbonate tablets
- Where
- 7 sites in China
- Volunteers
- 314 people
- Sponsor
- Chinese SLE Treatment And Research Group
Alveolar Bone Loss
Evaluation of Short Implants' Success for Teeth Replacement in Atrophic Posterior Mandibular Ridge
The aim of this study was to evaluate clinically and radiographically the splinted short implants' and single short implants' stability and bone condition before and after loading, in atrophic posterior mandibular alveolar ridges.
- Trial name
- NCT04414709
- Testing
- Double short implant, Single short implant
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Alexandria University
TIBIA PSEUDOARTHROSES
Segment Transport Versus Acute Shortening In The Treatment of Tibial Pseudarthroses With Bone Loss
In this study the investigators are presenting the advantages as well as the disadvantages of ACUTE SHORTENING AND RELENGTHENINIG VS SEGMENT TRANSPORT methods.
- Trial name
- NCT01246934
- Testing
- ASR METHOD
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Bezmialem Vakif University