Clinical trials: Otolaryngology
Inferior Turbinate Hypertrophy, Chronic Rhinosinusitis (CRS)
Efficacy of Lavender Aromatherapy on Anxiety and Pain Reduction During Awake Otolaryngologic Procedures
The purpose of this study is to evaluate the efficacy of lavender aromatherapy in adult patients undergoing awake otolaryngologic procedures in the outpatient clinic setting.
- Conditions
- Inferior Turbinate Hypertrophy, Chronic Rhinosinusitis (CRS), Rhinitis, Vasomotor, Thyroid Nodules
- Trial name
- NCT07299474
- Testing
- Lavender Aromatherapy
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Anesthesia
Prediction of Hemodynamic Reactivity During Suspension Laryngoscopy Using Analgesia/Nociception Index (ANI)
The aim of this study is to evaluate the performance of Analgesia/Nociception Index for the prediction of hemodynamic reactivity in adult patients undergoing suspension laryngoscopy on general anesthesia.
- Trial name
- NCT01796210
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Emmanuel Boselli
Anxiety, Consumer Satisfaction
Effect of Preoperative Information to Parents Before Ear-nose-throat Pediatric Surgery
Children who will have surgery and need anesthesia, and their parents are often anxious and show signs of stress and discomfort.
- Trial name
- NCT03763292
- Testing
- Specific information brochure
- Where
- Norway
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Reflux Disease, Reflux, Gastroesophageal
One-stop-shop Endoscopy in Reflux-patients: Evaluation of ENT and GI Features
Patients suffering from gastroesophageal reflux may suffer from both esophageal and laryngeal irritations. The investigators developed an endoscopic technique called functional endoscopy to evaluate alterations in the larynx and…
- Conditions
- Reflux Disease, Reflux, Gastroesophageal, Reflux, Laryngopharyngeal
- Trial name
- ENTGI-reflux (NCT05634187)
- Testing
- Functional endoscopy
- Where
- Germany
- Volunteers
- 190 people
- Sponsor
- University Hospital Muenster
Medical Education, User-Computer Interface
The Effect of Virtual Simulation Training in Mastoidectomy
The purpose of this study is to investigate the effect of virtual simulation training on mastoidectomy dissection performance of otorhinolaryngology trainees, to explore performance assessment using a final-product analysis…
- Conditions
- Medical Education, User-Computer Interface, Clinical Skills, Motor Skills
- Trial name
- NCT02030873
- Testing
- Virtual simulation training
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Obstructive Sleep Apnea
Obstructive Sleep Apnea Non-PAP Outcomes and Viable Alternatives
OSANOVA is a non-randomized clinical trial which aims to compare outcomes of mandibular advancement device (MAD) and hypoglossal nerve stimulation (HGNS) therapies in moderate-to-severe OSA patients who fail, decline, or are…
- Trial name
- OSANOVA (NCT07074288)
- Testing
- MAD, HGNS
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Washington University School of Medicine
Anesthesia, Complication
Effect of Neutrophil Lymphocyte-platelet Lymphocyte Ratio on Complications in Pediatric Patients
The aim of this study was to investigate the relationship between NLR, PLR and postoperative complications in children undergoing adenotonsillectomy and adenoidectomy.
- Trial name
- NLOPEDI (NCT03756909)
- Where
- Turkey (Türkiye)
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Rehabilitation, Neck Cancer
Rehabilitation Nursing Program in Otolaryngology
The European Commission's current political guidelines demonstrate into a joint plan aimed at improving and controlling cancer disease. Head and neck cancer (HNC) are the sixth most common cancer worldwide.
- Conditions
- Rehabilitation, Neck Cancer, Otorhinolaryngologic Neoplasms
- Trial name
- NCT05246891
- Testing
- rehabilitation nursing
- Where
- Portugal
- Volunteers
- 151 people
- Sponsor
- University of Évora
Pain, Acute, Vocal Fold Polyp
Patient Augmented Reality and Vibratory Array Otorhinolaryngology Procedures
In-office procedures (IOPs) are a cost-effective, and safe alternative to many operating room procedure, with benefits such as reduced anesthesia risk.
- Conditions
- Pain, Acute, Vocal Fold Polyp, Vocal Cord Paralysis, Laryngeal Neoplasms
- Trial name
- PARVA (NCT06227039)
- Testing
- Vibroacoustic stimulation on, Augmented Reality on, Vibroacoustic stimulation off
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Pain, Postoperative
Liposomal Bupivacaine vs Standard Bupivacaine for Post-Rhinoplasty Analgesia
The purpose of this study is to find out which pain medication is more effective in reducing pain after nose surgery (rhinoplasty).
- Trial name
- NCT07689162
- Testing
- Standard Bupivacaine, Liposomal Bupivacaine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Washington University School of Medicine
All Adult Patients Undergoing an Otolaryngology Procedure With Inhaled Methoxyflurane as an Adjunct to Topical or Local Anesthesia
Penthrox in Otolaryngology
Our objective is to explore the use of methoxyflurane anesthesia as an adjunct analgesic to local anesthesia during in-office otolaryngology procedures in a prospective pilot study.
- Trial name
- PenthroxOTL (NCT07003880)
- Testing
- Methoxyflurane anesthesia
- Volunteers
- 50 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Head and Neck Neoplasms
A Pilot Study of the Use of the DaVinci Robotic System for Otorhinolaryngology-Head and Neck Surgery
1. Patients included will have benign or malignant lesions with treatment plan for endoscopic resection or resection by other minimally invasive techniques. 2.
- Trial name
- NCT00627562
- Testing
- robot assisted endoscopic head and neck surgery using the DaVinci Robotic Surgical System
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Montefiore Medical Center
CerebroSpinal Fluid (CSF) Leak, Chronic Otitis Media
Cone Beam CT for Diagnosis of Select Otorhinolaryngology (ENT) Indications at Lower Dose
The study objective is to compare the CBCT images generated by the CS 9300 to those generated by conventional CT.
- Conditions
- CerebroSpinal Fluid (CSF) Leak, Chronic Otitis Media, Otospongiosis, Otosclerosis
- Trial name
- CBCT-ENT (NCT01855425)
- Testing
- Radiation
- Where
- 3 sites in United States, Belgium and 1 more
- Volunteers
- 96 people
- Sponsor
- Carestream Health, Inc.
Olfactory Disorder, Taste Disorders
Prospective Registery of Smell/Taste Clinic Ear/Nose/Throat
Smell/taste disorders are common conditions with a significant impact on quality of life. In September 2021, a specific consultation for patients with smell and taste disorders was initiated at the ENT-HNS (ear, nose, and throat…
- Conditions
- Olfactory Disorder, Taste Disorders, Smell Dysfunction, Smell Disorder
- Trial name
- ProspeRo'Scent (NCT06456008)
- Testing
- Standard of care
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Rate of Infections, Operating Site
Postoperative Surgical Site Infection afterENT Bone Flap Surgery
In 2017, the French Society in anesthesia and reanimation published new recommendations on intraoperative antibiotic prophylaxis.
- Conditions
- Rate of Infections, Operating Site, Post-operative Surgery, Bone Flap Surgery
- Trial name
- SSI-flap (NCT04492826)
- Testing
- Postoperative infections rate
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Hospices Civils de Lyon
Postoperative Pain, Patient Satisfaction
Post Operative Analgesia and Patient Satisfaction
To understand how patients perceive the quality of care they receive when given different post-operative analgesic medications. Specifically the investigators want to assess whether patients who receive non-opioid analgesia…
- Conditions
- Postoperative Pain, Patient Satisfaction, Analgesia
- Trial name
- NCT04976387
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Nasofibroscopy
Evaluation of Topic Anaesthesia for Laryngoscopy With Fibroscopy During Paediatric Ear Nose Throat (ENT)Consultation
The purpose of this work is to estimate the efficiency in terms of pain of the application of a local anesthetic (xylocaïne viscous 2%®) during the realization of an examination in naso-fiberscopy in consultation of ENT at the…
- Trial name
- NCT01125332
- Testing
- Indirect laryngoscopy in the flexible nasofibroscope
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Ear Infection, Telemedicine
Examination of the Applicability and Performance of Otolaryngology Telemedicine, Telediagnostics in Establishing the Diagnosis and Therapy of Otolaryngology Diseases
System/Device name: Otoscopic recording and clinical data telemedicine software supporting its transmission and analysis. Characteristics of the medical device: The device is applied to an iPhone with a CE mark also from a…
- Trial name
- TMED_FOG_001 (NCT06781164)
- Testing
- telemedicine
- Where
- Hungary
- Volunteers
- 103 people
- Sponsor
- Szeged University
Nasal Neoplasm, Nasal Neoplasm Benign
Prospective Study of Sinonasal and Skull-base Tumours Management
This observational prospective clinical study aims to describe the epidemiology, management and outcome of patients with sinonasal and skull-base pathology (tumours and diseases with malignant clinical characteristics) in a…
- Conditions
- Nasal Neoplasm, Nasal Neoplasm Benign, Skull Base Neoplasms, Skull Base Osteomyelitis
- Trial name
- Sinonasal_Tu (NCT05607888)
- Where
- Slovenia
- Volunteers
- 120 people
- Sponsor
- University Medical Centre Ljubljana
Otorhinolaryngologic Diseases
Psychiatric Comorbidity
The goals of this project are aimed at the following: 1. Identifying psychiatric comorbidity in patients presenting to the HNSCS clinic 1F and Duke Otolaryngology of Raleigh clinic using the validated assessment tool Brief…
- Trial name
- NCT02927652
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 463 people
- Sponsor
- Duke University