Clinical trials: Out-of Hospital Cardiac Arrest
Out-Of-Hospital Cardiac Arrest
EXecution of Trans-Esophagus Echo Cardiogram in CardioPulmonary Resuscitation for Patients With Out-of-hospital Cardiac Arrest
The purpose of this single center, randomized clinical control trial is to determine that changing chest compression site during cardiopulmonary resuscitation according to the examination of the TEE could increase the level of…
- Trial name
- EXECT_CPR (NCT05907460)
- Testing
- transesophageal echocardiography examination during cardiopulmonary resuscitation
- Where
- Taiwan
- Volunteers
- 132 people
- Sponsor
- Far Eastern Memorial Hospital
Cardiac Arrest
Pragmatic Airway Resuscitation Trial
The primary objective of the trial is to determine if 72-hour survival after out-of-hospital cardiac arrest (OHCA) is improved with initial endotracheal intubation (ETI) over initial laryngeal tube (LT) airway management…
- Trial name
- PART (NCT02419573)
- Testing
- Endotracheal Intubation, Laryngeal Tube (King)
- Where
- 6 sites in United States
- Volunteers
- 3,004 people
- Sponsor
- University of Alabama at Birmingham
Out of Hospital Cardiac Arrest
Artificial Intelligence Cerebral Gray-white Matter Ratio Module Usage in Hsinchu District Hsinchu District Using an Artificial Intelligence Cerebral Gray-white Matter Ratio Module
This study aims to establish an electronic medical record and imaging database for out-of-hospital cardiac arrest (OHCA) patients at NTUH Hsinchu Branch.
- Trial name
- NCT06856018
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- National Taiwan University Hospital
Out-of-hospital Cardiac Arrest
CPR Quality Between Flexible Stretcher and Standard Stretcher in OHCA
This study aims to compare the quality of emergency medical services cardiopulmonary resuscitation between flexible stretcher and standard stretcher during ambulance transport to hospital among out-of-hospital cardiac arrest…
- Trial name
- ASIA-CPR (NCT02527694)
- Testing
- Flexible EMS stretcher cart, mechanical CPR
- Where
- South Korea
- Volunteers
- 49 people
- Sponsor
- Seoul National University Hospital
Cardiac Arrest
Refractory Out-Of-Hospital Cardiac Arrest Treated With Mechanical CPR, Hypothermia, ECMO and Early Reperfusion
Sudden out-of-hospital cardiac arrest (OHCA) is a leading cause of death in Australia. The most common cause of OHCA is a heart attack.
- Trial name
- CHEER (NCT01186614)
- Testing
- Automated CPR, ECMO, Coronary angiography
- Where
- 2 sites in Australia
- Volunteers
- 24 people
- Sponsor
- Bayside Health
Out of Hospital Cardiac Arrest, Neurologic Symptoms
Can Optic Nerve Sheath Diameter Measurement Predict Negative Neurological Outcome ?
This study is designed as a multicenter, prospective, cohort clinical study. The out of hospital cardiac arrest (OHCA) patients presenting to the adult emergency departments of the participating hospitals will render the study…
- Trial name
- NCT02637258
- Testing
- Ultrasonographic Measurements of Optic Nerve Sheath Diameter
- Where
- 19 sites in Turkey (Türkiye)
- Volunteers
- 203 people
- Sponsor
- Emergency Medicine Association of Turkey
Out-Of-Hospital Cardiac Arrest, Cardiac Arrest
Technological and Patient-tailored Innovations for Maximizing Effectiveness of Cardiac Arrest Resuscitation
Out-of-hospital cardiac arrest (OHCA) affects 275,000 people in Europe every year. In Italy alone, 50,000 people experience OHCA annually, with only 9% surviving. Half of the survivors suffer severe brain damage.
- Trial name
- TIME-CARE (NCT06538155)
- Testing
- Wearable device, Cardiopulmonary resuscitation, CT scan, TEE exam, or chest X ray
- Where
- 3 sites in Italy
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Out-Of-Hospital Cardiac Arrest
Systemic Evaluation of the Etiologies of Young Adults With Non-traumatic Out-of-hospital Cardiac Arrest
The goal of this observational study is to establish the protocol of systemic analysis of the causes of non-traumatic cardiac arrest in young patients.
- Trial name
- NCT06122337
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Education, Medical, Undergraduate, Out-of-Hospital Cardiac Arrest
Serious Game Versus Online Course to Pre-train Medical Students on the Management of an Adult Cardiac Arrest.
The objective of this study is to compare two forms of pre-training (an online narrative presentation and a serious game) to prepare 2nd year medical students for a hands-on training with physical simulators about out-of-hospital…
- Conditions
- Education, Medical, Undergraduate, Out-of-Hospital Cardiac Arrest, Simulation Training
- Trial name
- NCT02758119
- Testing
- Serious Game, Online course
- Where
- France
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Ilumens
Out-of-hospital Cardiac Arrest (OHCA), Emergency Medical Services
Telemedicine-Assisted vs Conventional Telephone Instruction in Cardiopulmonary Resuscitation
Out-of-hospital cardiac arrest (OHCA) is a life-threatening emergency where early cardiopulmonary resuscitation (CPR) by bystanders can significantly improve survival.
- Trial name
- TACTIC (NCT07546474)
- Testing
- Telemedicine-Assisted CPR (TA-CPR), Dispatcher-Assisted CPR (DA-CPR)
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Siriraj Hospital
Cardiac Arrest
Non-invasive Neurological Evaluation During CPR
Cardiac arrest remains a leading cause of death, currently affecting >250,000 Europeans outside the hospital each year. Manual cardiopulmonary resuscitation (CPR) provides between 15 to 30 % of normal blood flow to the heart and…
- Trial name
- Neuro-E-CPR (NCT02684955)
- Testing
- Cerebral spectroscopy, Pupillometry
- Where
- 2 sites in France
- Volunteers
- 112 people
- Sponsor
- University Hospital, Grenoble
Cardiac Arrest (CA)
Treatment Outcome in Patients After eCPR
This study consists of two parts - retrospective and prospective. The aim of this study is to assess the quality of life in bio-psycho-social dimensions in patients after eCPR (extracorporeal cardiopulmonary resuscitation), in…
- Trial name
- NCT07031466
- Testing
- Retrospective analysis of assigned treatment, Quality of Life (SF-36), Quality of Life (EQ-5D)
- Where
- 2 sites in Czechia
- Volunteers
- 74 people
- Sponsor
- University Hospital Ostrava
Out-of-Hospital Cardiac Arrest, Sudden Cardiac Death
The Effect of Chest Compression and Ventilation Coordination During Cardiopulmonary Resuscitation.
Airway management and maintaining adequate ventilation during cardiopulmonary resuscitation (CPR) are important. The rule of 30:2 compression-to-ventilation ratios before endotracheal intubation and keeping 1 breath every 6-8…
- Trial name
- NCT02056509
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Out-of-hospital Cardiac Arrest (OHCA)
Potassium Chloride in Out-of-hospital Cardiac Arrest Due to Refractory Ventricular Fibrillation
The purpose of this study is to evaluate, in patients presenting with out-of-hospital cardiac arrest (OHCA) by ventricular fibrillation, refractory to 3 external electric shocks, the efficacy of a direct intravenous injection of…
- Trial name
- POTACREH (NCT04316611)
- Testing
- Potassium chloride
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Out-Of-Hospital Cardiac Arrest
Clinical Trial of Sodium Nitrite for Out of Hospital Cardiac Arrest
In this clinical study, a total of 1500 patients with out-of-hospital cardiac arrest in Seattle/King County will be enrolled. This will be a randomized clinical trial and patients will receive either two different doses of IV…
- Trial name
- SNOCAT (NCT03452917)
- Testing
- sodium nitrite 45 mg, sodium nitrite 60 mg
- Where
- United States
- Volunteers
- 1,502 people
- Sponsor
- University of Washington
Out-Of-Hospital Cardiac Arrest
REmote COnditioning in Out-of-Hospital Cardiac Arrest
Out-of-Hospital Cardiac Arrest remains a major public health problem, resulting in high mortality largely related to multiple organ failure and poor neurological outcomes due to brain anoxia.
- Trial name
- RECO-OHCA (NCT06306625)
- Testing
- Remote ischemic conditioning, No remote ischemic conditioning
- Where
- 14 sites in France
- Volunteers
- 220 people
- Sponsor
- Hospices Civils de Lyon
Cardiac Arrest, Out-Of-Hospital
Drone Delivered Defibrillators (The 3D Project).
The goal of this observational study is to explore the optimisation and integration of a drone-delivered Automated External Defibrillator (AED) system into the pre-hospital response to out-of-hospital cardiac arrest.
- Trial name
- NCT06334718
- Testing
- Interviews and simulation
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Warwick
Cardiac Arrest (CA)
The Variation in Electrode Configuration for Termination of Out-of-Hospital Rhythms That Are Shockable in Cardiac Arrest Trial
The purpose of this study is to compare the effectiveness of two defibrillator pad placements, one where pads are placed on the front of the chest and back (anterior-posterior [AP]) and one where the pads are placed on the front…
- Trial name
- VECTORS (NCT07818785)
- Testing
- defibrillator electrode pads
- Volunteers
- 1,500 people
- Sponsor
- Oregon Health and Science University
Out-of-hospital Cardiac Arrest
Target Temperature Management After Cardiac Arrest
Experimental studies and previous clinical trials suggest an improvement in mortality and neurological function with hypothermia after cardiac arrest.
- Trial name
- TTM (NCT01020916)
- Testing
- Target temperature 36°C, Target Temperature 33°C
- Where
- 33 sites in Australia, Czechia and 8 more
- Volunteers
- 950 people
- Sponsor
- Niklas Nielsen
Out of Hospital Cardiac Arrest
Functional Outcome After Cardiac Arrest
Descriptive and prognosis study of the functional outcome after cardiac arrest for the patients awake within the first 15 days.
- Trial name
- HANOX (NCT02292147)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris