Clinical trials: Over Cancer
Healthy
Bioavailability Study of 300 mg Trazodone Hydrochloride (New Polymer) vs. 300 mg Trazodone Hydrochloride (Contramid® Prolonged-release Tablets) Under Fasting Conditions
This study was designed to investigate the bioequivalence of the test and reference products when administered as single oral doses in two consecutive study periods, under fasting conditions.
- Trial name
- NCT05136521
- Testing
- Trazodone HCl - new polymer, Trazodone HCl - Contramid®
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Human Papillomavirus Infection, Genital Warts
The Epidemiologic Study of Human Papillomavirus Infection and Related Diseases
primary purpose:Evaluate the prevalence and incidence of HPV infection and related diseases in subjects. Secondary purpose:Analyze risk factors of HPV infection and related diseases.
- Trial name
- NCT02188004
- Where
- China
- Volunteers
- 4,691 people, healthy volunteers welcome
- Sponsor
- Jun Zhang
Head and Neck Cancer
Magnesium Sulphate and Rocuronium in Patients Over 60
The purpose of this study is to evaluate the effects of MgSO4 administration on the pharmacodynamics of rocuronium in patients with 60 or more years of age.
- Trial name
- NCT01804205
- Testing
- Magnesium Sulfate
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Pedro Rotava
Breast Neoplasm
Giving Information on the Risks and Limitations of Mammography Screening (GIRLS)
To trial the provision of full information on the benefits and risks of mammography in women that are eligible for breast screening.
- Trial name
- GIRLS (NCT02914197)
- Testing
- Full information
- Where
- Canada
- Volunteers
- 608 people, healthy volunteers welcome
- Sponsor
- McMaster University
Lung Cancer
Efficacy and Safety of Omega 3 Fatty Acid Supplements on Heavy Smokers
The study duration is 12 months. The initial enrollment visit will take approximately one hour. The Month 1, 3, 6, 7, 9 and 12 visits will take approximately 30 minutes each.
- Trial name
- Omega (NCT03936621)
- Testing
- Omega 3 fatty acid
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- British Columbia Cancer Agency
Healthy, Men
Bioavailability of Legume Proteins in Differents Products
The use of pea proteins could be interesting in specific foods. Indeed, these proteins could have great nutritional quality, with good amino acid profile.
- Trial name
- LEG'UP (NCT06624033)
- Testing
- amino acids kinetics
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Leukemia (Both ALL and AML), Cancer of Lung
Changing Over Time of Ascorbic Acid After Chemotherapy
Rationale: Recent studies showed that ascorbic acid (AA) stimulates proliferation and maturation of T lymphocytes and NK cells. Chemotherapy results in depletion of those cells and thereby an increased infection rate.
- Conditions
- Leukemia (Both ALL and AML), Cancer of Lung, Myeloma
- Trial name
- NCT02931942
- Testing
- blood withdrawn
- Where
- Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Breast Neoplasms
Australian Screening Mammography Decision Aid Trial (ASMDAT)
The purpose of the study is to develop and evaluate a decision aid to assist women aged 70 years and over to make an informed choice about whether to continue screening mammography.
- Trial name
- NCT00247442
- Testing
- Decision aid
- Where
- Australia
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- University of Sydney
Cancer
Ipatasertib (GDC-0068) Study to Evaluate Formulation Change and Food Effect on Bioavailability in Healthy Subjects
This Phase I, open-label, randomized, 3-period crossover study was designed to determine the relative bioavailability of ipatasertib administered as capsule and tablet formulations to healthy volunteers.
- Trial name
- NCT02536391
- Testing
- Ipatasertib (capsule), Ipatasertib (tablet)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Genentech, Inc.
Hypercholesterolemia, Breast Cancer
Plant Sterol INtervention for Cancer Prevention (PINC)
Several types of human cells convert cholesterol into other molecules, including oxysterols. Oxysterols can promote breast cancer growth and help tumours to spread.
- Conditions
- Hypercholesterolemia, Breast Cancer, Obesity
- Trial name
- PINC (NCT04147767)
- Testing
- Cholesterol Reducing Strawberry Yogurt Drink (Tesco Ltd), Low Fat Strawberry Yogurt Drinks (Morrisons Ltd)
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Endometriosis, Endometrial Cancer
Serum Trace Element Levels in Some Gynecological Diseases
The aim of this clinical study is to measure the levels of various trace elements in the blood serum of women with various gynecological diseases and to compare them with healthy controls.
- Conditions
- Endometriosis, Endometrial Cancer, Over Cancer, Healthy Control
- Trial name
- NCT07210918
- Testing
- Blood Product
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Drug Interactions, Neoplasms
A Cross-over Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics (PK) of GSK525762 in Healthy Female Subjects of Non Child Bearing Potential
This is a Phase I, single center, two-part, randomized, open label, cross-over study. Part 1 of this study will evaluate the PK, safety, and tolerability of GSK525762 when administered alone and when co-administered following…
- Trial name
- NCT02706535
- Testing
- GSK525762 Besylate Tablets, Itraconazole 200 mg, Rifampicin 300 mg
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Lymphoma
A Relative Bioavailability Study of Different Processes of SHR2554 Tablets in Healthy Adult Subjects
TThe study is being conducted to evaluate the relative bioavailability, pharmacokinetics and safety of different tablet processes of SHR2554 in healthy adult subjects.
- Trial name
- NCT05049083
- Testing
- New Process SHR2554 tablet、Former Process SHR2554 tablet, Former Process SHR2554 tablet、New Process SHR2554 tablet
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Breast Cancer Screening
Messaging Strategies to Reduce Breast Cancer Over-screening in Older Women
This is an online survey experiment with data collection over 2 time points two weeks apart. This is Aim 2 of a three-aim R01 project; overall project goal is to better understand how messages from different sources interact to…
- Trial name
- NCT05821023
- Testing
- messages
- Where
- United States
- Volunteers
- 4,173 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cancer, Rectum
Converted Laparoscopic Resection of Upper Rectal Carcinoma T1-4 N0-1 in Obese Patients.
Background: laparoscopic resection (LAR) is a safe approach and widely used for rectal cancer after neoadjuvant chemo-radiotherapy, but short term and oncological outcome for converted cases to open surgery (cLAR), may be…
- Trial name
- NCT04401787
- Testing
- Anterior resection for upper rectal cancer in obese
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
Comparison of the Extent to Which the Drug Given as Two Different Capsule Sizes Becomes Available to the Body
Researchers are looking for a new way to treat women who have symptoms by hormonal changes, like those that happen in women during menopause. These symptoms can include hot flashes, night sweats, and changes in blood pressure.
- Trial name
- NCT04845841
- Testing
- Elinzanetant (BAY3427080) treatment A, Elinzanetant (BAY3427080) treatment B
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Bayer
Patient Educational Materials
Patient Educational Materials for Prostate Cancer Screening
Although the harms of screening for prostate cancer with the prostate-specific antigen (PSA) test outweigh the benefits, 560,000 Ontario men undergo PSA screening each year.
- Trial name
- NCT03222466
- Testing
- Co-created PEM
- Where
- Canada
- Volunteers
- 573 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Healthy
Relatively Healthy Male Veterans Observed Over Time to See What Types of Diseases Develop
The purpose of this study is to gather a mixed racial group of relatively healthy male Veterans (for example, White, African-American, and Hispanic), who are at least 50 years of age.
- Trial name
- ACTIVE Health (NCT00076141)
- Where
- 9 sites in United States
- Volunteers
- 991 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Neoplasms
ABSK021 Food Effect Study in Healthy Subjects
This is a randomized, open-label, two-sequence, two-cycle, cross-over study to evaluate the relative bioavailability of ABSK021 after single-dose fasting and high-fat postprandial administration in healthy subjects
- Trial name
- NCT05280483
- Testing
- ABSK021 with fed state, ABSK021 with fasted state
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Abbisko Therapeutics Co, Ltd
Functional Disability, Dementia
Aspirin in Reducing Events in the Elderly-Extension (ASPREE-XT)
ASPREE-XT is a post-treatment, longitudinal observational follow-up study of ASPREE participants. Although the ASPREE trial medication was ceased, the study activity was not stopped and ASPREE participants are continuing with…
- Conditions
- Functional Disability, Dementia, Heart Disease, Stroke
- Trial name
- NCT07224347
- Where
- 36 sites in United States, Australia
- Volunteers
- 19,114 people, healthy volunteers welcome
- Sponsor
- Anne Murray