Clinical trials: Overactive Bladder, completed
Overactive Bladder
TTNS vs PTNS in a County Hospital System.
The goal of this clinical trial is to study whether transcutaneous tibial nerve stimulation (TTNS) is a feasible and satisfactory treatment for overactive bladder in Urogynecology patients who receive their care at a county…
- Trial name
- NCT07353944
- Testing
- Tibial nerve stimulation
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Overactive Bladder
ADRB3, ROCK2 and GEF Levels in Overactive Bladder Patients
Aims: To evaluate changes in levels of ADRB3, ROCK2, and GEF which have key roles in the adrenergic and cholinergic pathways of contraction-relaxation harmony in voiding physiology, and to investigate the diagnostic potential of…
- Trial name
- NCT04626960
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Overactive Bladder
Transcutaneous Posterior Tibial Nerve Electrostimulation With Low Dose Trospium Chloride in OAB in Females
This study was done to verify whether the combination of transcutaneous posterior tibial nerve stimulation (TPTNS) with low dose trospium chloride in the treatment of females with overactive bladder (OAB) would be more effective…
- Trial name
- NCT03104101
- Testing
- TPTNS+Drug, TPTNS
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Overactive Bladder, Urge Incontinence
Lidocaine Patches Prior to Percutaneous Nerve Evaluation
The study will be a double-blind randomized control trial comparing 4% lidocaine patch placed over the sacrum 3 minutes prior to a percutaneous nerve evaluation (PNE) procedure to a placebo patch in patients already scheduled to…
- Conditions
- Overactive Bladder, Urge Incontinence, Fecal Incontinence
- Trial name
- NCT05783219
- Testing
- Lidocaine patch
- Where
- 2 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Overactive Bladder and Urge Urinary Incontinence
The New Possibility of Treating Overactive Bladder With Radiofrequency
A prospective, randomized, single-blind, placebo-controlled study was conducted from June 2023 to May 2025. The study enrolled 95 women (N=48 in the study group; N=47 in the placebo group) who presented with confirmed symptoms of…
- Trial name
- RF and OAB (NCT07398014)
- Testing
- radiofrequency - TECAR
- Where
- Slovenia
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University Maribor
Healthy Volunteer, Pharmacokinetics of YM178
A Study to Investigate the Safety and Effect of Food on the Pharmacokinetics of YM178 in Healthy Volunteers
The purpose of the study is to evaluate safety of YM178 and the effect of food intake on the pharmacokinetics of YM178 in healthy adult subjects.
- Trial name
- NCT01334905
- Testing
- YM178
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Overactive Bladder
Pilot Study: Is Overactive Bladder Caused by Subacute Urinary Tract Infections?
The purpose of this study is to look for evidence of bacteria in the urine or bladder of people with overactive bladder. Because you do not have overactive bladder, your participation in this study will be used as a comparison to…
- Trial name
- NCT00714792
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Overactive Bladder
Percutaneous Tibial Nerve Stimulation Maintenance: Monthly Therapy or Per Patient Requested Need
The overall objective of this study is to compare the efficacy of the standard monthly maintenance therapy for percutaneous tibial nerve stimulation (PTNS), to sessions as the patient needs (prn) between 2 weeks and 12 weeks…
- Trial name
- NCT03136601
- Testing
- PTNS maintenance
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Urge Incontinence, Overactive Bladder
Red Clover Isoflavones in Postmenopausal Women With Urge Urinary Incontinence and Overactive Bladder
The purpose of this study is to investigate the effect of red clover isoflavones in postmenopausal women with and without urge urinary incontinence and overactive bladder
- Trial name
- NCT05013593
- Testing
- Red Clover Extract (RCE)
- Where
- Denmark
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Regionshospital Nordjylland
Overactive Bladder, Urgency-frequency Syndrome
TEST-ON - Does iStim Reduce Urinary Urgency?
Overactive bladder (OAB) is a chronic disorder with an overall prevalence in the adult population of over 10%, but that may exceed 40% in elderly groups.
- Conditions
- Overactive Bladder, Urgency-frequency Syndrome, Urinary Frequency More Than Once at Night
- Trial name
- TEST-ON (NCT04957524)
- Testing
- iStim TENS unit and Transvaginal Probe
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Overactive Bladder
A Clinical Trial to Evaluate the Efficacy and Safety of DR-3001 in Women With Overactive Bladder
This is a multicenter study to evaluate the efficacy and safety of 2 different doses of DR-3001. For eligible subjects the duration of the study will be approximately 20 weeks; this will consist of a 4-week screening period, a…
- Trial name
- NCT00685113
- Testing
- DR-3001
- Where
- 84 sites in United States, Canada
- Volunteers
- 1,104 people, healthy volunteers welcome
- Sponsor
- Duramed Research
Overactive Bladder, Pharmacokinetics
A Clinical Study to Determine the Effect of YM178 on the Pharmacokinetics of Warfarin in Healthy Subjects
This study investigates whether YM178 has an effect on the pharmacokinetics of warfarin, to exclude any drug-drug interaction between YM178 and warfarin, and evaluates the safety and tolerability of warfarin alone and combined…
- Trial name
- NCT00856570
- Testing
- warfarin, YM178
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Overactive Bladder
Bacterial Genomic Sequencing in Overactive Bladder
No one really knows what causes overactive bladder syndrome (OAB). Urinary tract infection (UTI)causes similar symptoms to OAB with the difference being the presence of bacteria, as evidenced by routine microbiology cultures.
- Trial name
- NCT01642277
- Testing
- Solifenacin
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Loyola University
Detrusor Overactivity
Ultrasonographic Bladder Wall Thickness and Different Forms of Detrusor Overactivity
In the last decade, several authors proposed ultrasound measurement of Bladder wall thickness (BWT) for the screening of the voiding dysfunction and of the detrusor overactivity (DO).
- Trial name
- NCT01003457
- Testing
- ultrasonography
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Università degli Studi dell'Insubria
Endometriosis Related Pain, Overactive Bladder
A Trial to Learn How a New Liquid Form of BAY1817080 is Tolerated and Taken up by the Body of Healthy Male Participants (Part A). By Labeling BAY1817080 With a Radioactive Substance (Carbon 14) Researchers Want to Learn How the Study Drug is Processed and Excreted by the Body After Dosing (Part B)
Researchers are looking for a new way to treat people suffering either from a condition where the bladder is unable to hold urine normally (overactive bladder), or a condition in which tissue similar to the tissue that normally…
- Conditions
- Endometriosis Related Pain, Overactive Bladder, Diabetic Neuropathic Pain, Refractory or Unexplained Chronic Cough
- Trial name
- NCT04487431
- Testing
- BAY1817080, [14C]BAY1817080
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy Subjects, Overactive Bladder
Evaluate the Safety, Tolerability and PK of Different Formulations of Orally Administered Solabegron in Healthy Male Subjects
The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of different formulations of orally administered solabegron in healthy male subjects.
- Trial name
- NCT02938507
- Testing
- Formulation 1 solabegron, Formulation 2 solabegron
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Velicept Therapeutics, Inc.
Stress Incontinence, Female, Overactive Bladder
Mindfulness Exercises to Reduce Anxiety and Pain During Urodynamic Testing
In this pilot study the investigators attempt to answer the question, does mindfulness exercises before urodynamic testing reduce patient's perception of anxiety or pain?
- Conditions
- Stress Incontinence, Female, Overactive Bladder, Lower Urinary Tract Symptoms
- Trial name
- NCT03625843
- Testing
- Mindfulness exercises
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- San Antonio Uniformed Services Health Education Consortium
Lower Urinary Tract Symptoms
Symptoms of Lower Urinary Tract Dysfunction Phenotyping Study
The purpose of this study is to advance our understanding of people who experience urinary and bladder problems. We are interested in learning about people's experiences with urinary symptoms and how these symptoms will be…
- Trial name
- NCT02485808
- Testing
- None-observational, Magnetic Resonance Imaging (MRI), Multimodal Automated Sensory Testing System
- Where
- 6 sites in United States
- Volunteers
- 1,879 people, healthy volunteers welcome
- Sponsor
- Arbor Research Collaborative for Health
Overactive Bladder
Management of OAB in Female Patients .
The objective of this study is to compare the effectiveness of mirabegron, solifenacin, tadalafil (5mg), and their combination in relieving symptoms of overactive bladder (OAB) in a double-blinded prospective randomized…
- Trial name
- NCT06184334
- Testing
- Solfenacin, Mirabegron, Tadalafil 5mg
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Elsayed Abdelhalim Elsayed
Overactive Bladder
Hypnotherapy for Treatment of Overactive Bladder
The investigators purpose is to perform a pilot study evaluating the efficacy in hypnotherapy in treating women with Overactive Bladder Symptoms (urinary urgency symptoms and urinary frequency).
- Trial name
- NCT00793611
- Testing
- Behavioral therapy standard of care, hypnotherapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of New Mexico